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A Daya Terima Dan Kandungan Fitokimia ( Antioksidan, Serat, Indeks Glikemik, Dan Vitamin C) Pada Minuman Sehat Mar'ke Billar Sebagai Alternatif Pencegahan Obesitas: Daya Terima dan Uji Kandungan Fitokimia (Antioksidan, Serat, Indeks Glikemik, dan Vitamin C) pada Minuman Sehat Mar'ke Bilar sebagai Alternatif Pencegahan Obesitas Siahaan, Ginta; Tarigan, Novriani; Siregar, Ice Ratnalela
Amerta Nutrition Vol. 7 No. 2SP (2023): AMERTA NUTRITION SUPPLEMENTARY EDITION Special 3rd Amerta Nutrition Conferenc
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v7i2SP.2023.224-231

Abstract

Background: Obesity is a multifactorial disease that occurs due to excessive storage of fat tissues. The World Health Organization (WHO) states that obesity and overweight are risk factors for the fifth cause of death in the world. A nutritional status monitoring initiated by the Directorate of Community Nutrition of the Indonesian Ministry of Health in 2018 showed that the percentage of the obese adult population aged >18 years was 28.5%, and the 2018 Basic Health Research found 21.8% of the population. Obesity can be prevented by consuming fruits and tubers that are high in fiber, vitamin C, antioxidants, and low glycemic index (GI) value. Objectives: This study aims to determine the acceptability and phytochemical test of antioxidant, fiber, glycemic index, and vitamin C of Mar'ke Bilar, a healthy drink. Methods: Experimental research was conducted using a complete randomized design (CRD) consisting of three treatments and two repetitions. Antioxidant, vitamin C, fiber, and GI levels were assessed afterward. Results: The organoleptic test results show the highest acceptability obtained in formulation 2 consisting of 30 ml passion fruit, 50 ml persimmon, 50 ml purple sweet potato, and 70 ml water. Formulation 2 contained 39.73 mg/ml antioxidant, 4.0 g fiber, 62% GI, and 56.81 mg vitamin C. This means that Mar'ke Bilar can be used as an alternative to obesity prevention. Conclusions: Formulation 2 is the selected formulation in which the drink is purplish pink, not too thick, watery, refreshingly sweet, and slightly sour with a total antioxidant content of 39.73 mg/ml, 4.0 g of fiber, GI of 62%, and vitamin C of 56.81 mg.
Gambaran Hasil Pemeriksaan Hepatitis C Virus (HCV) Pada Pendonor Darah Di UDD PMI Kota Medan Dalimunthe, Afrina Yulia; Siregar, Ice Ratnalela; Rahmah, Lestari; Lubis, Nita Andriani
Jurnal Ilmu Kedokteran dan Kesehatan Vol 12, No 11 (2025): Volume 12 Nomor 11
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v12i11.21358

Abstract

Hepatitis C Virus (HCV) adalah virus yang menyerang hati dan ditularkan terutama melalui darah, termasuk melalui transfusi darah yang tidak aman. Penelitian ini bertujuan untuk mengetahui gambaran hasil pemeriksaan HCV pada pendonor darah di Unit Donor Darah (UDD) PMI Kota Medan. Penelitian ini menggunakan desain deskriptif dengan pendekatan survei. Penelitian dilakukan pada April 2025 di UUD PMI Kota Medan menggunakan metode CLIA. Sampel terdiri dari 87 pendonor darah yang diperiksa menggunakan metode Chemiluminescent Immunoassay (CLIA). Ditemukan 4 pendonor (4,6%) reaktif HCV dan 83 pendonor (95,4%) non-reaktif. Kasus reaktif lebih banyak ditemukan pada laki-laki (3 orang) dibandingkan perempuan (1 orang), dan pada usia dewasa antara 23 hingga 52 tahun. Meskipun telah melalui tahap seleksi awal, pendonor masih dapat membawa infeksi HCV. Skrining ketat Infeksi Menular Lewat Transfusi Darah (IMLTD) harus diterapkan secara menyeluruh. Hasil tersebut mengindikasikan bahwa skrining donor darah perlu diperketat dengan metode molekuler.
Sistemic Review and Meta-Analysis: PCR For Early Detection Of Infection Intrauterine And Prediction Obstetric Complications In High-Risk Pregnancy Evi Irianti; Siregar, Ice Ratnalela
Jurnal Teknokes Vol. 18 No. 4 (2025): Desember
Publisher : Jurusan Teknik Elektromedik, Politeknik Kesehatan Kemenkes Surabaya, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35882/jteknokes.v18i4.120

Abstract

Intrauterine infection is a major cause obstetric complications, including preterm birth, premature rupture of membranes (PROM), and low birth weight (LBW). Polymerase Chain Reaction (PCR) testing offers rapid and sensitive molecular detection compared to conventional diagnostic methods. This study is a systematic review and meta analysis conducted following the PRISMA 2020 guidelines, aimed at evaluating the effectiveness of PCR in detecting intrauterine infection and predicting performed using PubMed, Scopus, ScienceDirect, Wiley and SpringerLink (2020 - 2025). The pooled analysis demonstrated a sensitivity of 0.90, specificity of 0,93 and an Area Under the Curve (AUC) of 0,95 with a Diagnostic Odds Ratio (DOR) of approximately 120. Postive PCR results were significantly associated with an increased risk of preterm birth (OR 3,4), LBW (OR 2,8) and PROM (OR 2,2). PCR demonstrated high diagnostic accuracy and strong prognostic value, supporting its integration into risk based antenatal screening to reduce perinatal morbidity and mortality.