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All Journal Jurnal Anestesiologi Indonesia JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) Syntax Literate: Jurnal Ilmiah Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Prima Medika Sains Infokes : Jurnal Ilmiah Rekam Medis dan Informasi Kesehatan JOURNAL LA MEDIHEALTICO Archives of The Medicine and Case Reports Bioscientia Medicina : Journal of Biomedicine and Translational Research Buletin Kedokteran dan Kesehatan Prima Jurnal Pendidikan Indonesia (Japendi) Eduvest - Journal of Universal Studies Ranah Research : Journal of Multidisciplinary Research and Development Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran JUKEJ: Jurnal Kesehatan Jompa
Simbolon, Boyke Marthin
Faculty Of Medicine, Universitas Prima Indonesia, Medan, Indonesia
Aerospace Engineering Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Transportation Veterinary Other

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Pengaruh komunikasi dan pemberian insentif terhadap kinerja perawat di RSU Royal Prima Medan Molek, Molek; Nasution, Sri Lestari Ramadhani; Simbolon, Boyke Marthin
Jurnal Prima Medika Sains Vol. 1 No. 1 (2019): Desember
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (334.515 KB)

Abstract

Nurse performance is one of the determinants of hospital success rate in providing health services. Efforts to improve nurse performance include paying attention to nurses' work stress. The purpose of this study was to determine the effect of communication and incentives for nurses' performance in the inpatient room at Royal Prima Hospital Medan. This type of cross-sectional research with an explanatory research method approach. The total population of 41 nurses and all nurses used as respondents (total sampling). Data were analyzed using the chi-square test and logistic regression was used to obtain an OR (Odds Ratio) value. The results showed nurses with good communication would increase performance by 6.7 times (p = 0.012: OR = 6.708) and the provision of incentives would increase performance by 6.6 times (p = 0.006; OR = 6.667).
Opioid and the usage in chronic non cancer pain Simbolon, Boyke Marthin
Jurnal Prima Medika Sains Vol. 5 No. 2 (2023): December
Publisher : Program Studi Magister Kesehatan Masyarakat Universitas Prima Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/jpms.v5i2.4613

Abstract

The use of opioid in various guidelines for chronic non-cancer pain is controversial because evidence of their long-term benefits is weak. The potential for serious adverse effects and local regulations warrant caution in both prescribers and users. However, opioids have a role in the management of chronic non-cancer pain in carefully selected patients with regular monitoring and as a part of multimodal therapy. Common adverse effects should be treated promptly to improve patient compliance. We believe that opioid therapy at low doses is beneficial in some patients. It should not be denied but carefully considered on a case-by-case basis.
Uji Keefektivitas Sedatif Hipnotik Ekstrak Daun Keji Beling (Strobilanthes Crispus) terhadap Gangguan Tidur (Insomnia) pada Mencit Immanuella Pinem; Muhammad Chairul; Boyke Marthin Simbolon
Jurnal Anestesi Vol. 3 No. 1 (2025): Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran
Publisher : Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59680/anestesi.v3i1.1630

Abstract

This study aimed to evaluate the sedative-hypnotic effectiveness of keji beling leaf extract (Strobilanthes crispus) on sleep disturbances (insomnia) in mice. The method employed was an experimental design with a completely randomized design (CRD). The study subjects were healthy male mice aged 2–3 months with body weights of 20–30 grams, divided into five treatment groups: negative control, positive control (diazepam), and three groups with EEDKB doses (100 mg/Kg BW, 300 mg/Kg BW, and 500 mg/Kg BW). The fireplace test method was used to assess sleep activity. Data were analyzed using a One Way ANOVA test. The results indicated a significance value of 0.000 (< 0.05), suggesting significant differences in sedative-hypnotic effectiveness among the control and treatment groups. In conclusion, EEDKB demonstrated significant sedative effects, with effectiveness increasing proportionally to the dosage
Comparison of Pain Scale and Duration of Early Mobilization after Cesarean Section Surgery Using Eracs Tap Block Method with Eracs without Tap Block Siburian, Tissa Priscillya Deabitha Br; Simbolon, Boyke Marthin; Chairul, Muhammad
Journal La Medihealtico Vol. 5 No. 5 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i5.1679

Abstract

One of the problems for pregnant women is dealing with pain and recovering quickly after surgery. This research focuses on observing pregnant women after surgery to compare the pain scale and duration of early post-operative mobilization using ERACS tap blocks and ERACS without tap blocks. This quantitative research was designed using a cross-sectional approach. The research sample was 40 respondents selected by purposive sampling. The pain scale was measured using the Visual Analog Scale (VAS) and Early Mobilization was measured using an observation sheet. Based on the results of statistical analysis. The p value in the results of the Mann-Whitney test analysis on the pain scale for both variables is VAS5 (24 hours) which has a p value of 0.028 which is lower than 0.05. Early mobilization shows that catheter removal has a p value of 0.002, lower than 0.05. It can be concluded that there is a significant difference between the pain scale and the duration of early mobilization using ERACS tap block and ERACS without tap block.
Perbandingan Shivering Pasien Pasca Operasi Sectio Caesarea Metode Eracs Tap Blok, Eracs Tanpa Tap Blok Dhillon, JagRoshen Singh; Simbolon, Boyke Marthin
JUKEJ : Jurnal Kesehatan Jompa Vol 4 No 3 (2025): JUKEJ: Jurnal Kesehatan Jompa
Publisher : Yayasan Jompa Research and Development

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57218/jkj.Vol4.Iss3.1999

Abstract

Shivering pasca anestesi spinal pada operasi sectio caesarea dapat meningkatkan konsumsi oksigen dan menurunkan kenyamanan pasien. Penelitian ini bertujuan menilai pengaruh penerapan Transversus Abdominis Plane (TAP) block dalam protokol Enhanced Recovery After Caesarean Section (ERACS) terhadap kejadian shivering pasca operasi. Penelitian dilakukan dengan desain observasional cross-sectional pada 40 pasien sectio caesarea dengan anestesi spinal yang dibagi menjadi dua kelompok, yaitu ERACS dengan TAP block (n = 20) dan ERACS tanpa TAP block (n = 20). Kejadian shivering dinilai menggunakan skala 0–4, dan data dianalisis dengan uji Chi-square atau Fisher’s Exact Test, serta ukuran asosiasi dinyatakan sebagai Prevalence Ratio (PR) dengan 95% Confidence Interval (CI). Hasil menunjukkan bahwa kejadian shivering lebih rendah pada kelompok ERACS dengan TAP block (45%) dibandingkan kelompok tanpa TAP block (85%) dengan PR = 1,89; 95% CI = 1,13–3,17; p = 0,02. Penerapan TAP block sebagai bagian dari protokol ERACS terbukti menurunkan risiko shivering pasca operasi sectio caesarea dan mendukung penggunaannya sebagai strategi analgesia multimodal yang efektif untuk meningkatkan kenyamanan dan pemulihan pasien.
Comparison Of Post-Cesarean Section Pain Medication With Spinal Anesthesia Method Eracs And Without ERACS Simbolon, Boyke Marthin; Akrom, Thoriq; Chairul, Muhammad
Eduvest - Journal of Universal Studies Vol. 4 No. 11 (2024): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v4i11.49923

Abstract

This study focused on the observation of pregnant women after surgery to determine the comparison of drugs and pain scales after surgery with the ERACS method and the method without ERACS. This study aims to determine the comparison of drugs and pain scales in patients after Sectio Caesarea surgery using the ERACS method and without ERACS. Currently, the Enhanced Recovery After Caesarian Surgery (ERACS) method as a perioperative program is popular, because it is considered to have a faster healing time and minimize pain so as to provide comfort to patients. This quantitative study was designed using a Cross-Sectional approach. The research sample was 40 respondents whose Pain Scale was measured using the Visual Analog Scale (VAS) measured with an observation sheet. Based on the results of statistical analysis. In the results of the Univariate test analysis on drug administration and pain scales of both VAS variables after (24 hours). It can be concluded that there is a difference between the amount of pain medication given and the pain scale with the ERACS method and the method without ERACS. The ERACS method has been shown to be more effective in reducing pain after Sectio Caesarea surgery and accelerating patient recovery compared to the method without ERACS. These findings support the use of the ERACS method as a standard of care to improve patient comfort and clinical efficiency
Test of The Effectiveness of Sweet Wood (Cinnamomum Burmanii) on Healing of Wood Wounds in Wistar Rats Chairul, Muhammad; Sinaga, Stevani Rose Br; Simbolon, Boyke Marthin
Eduvest - Journal of Universal Studies Vol. 5 No. 1 (2025): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i1.50271

Abstract

Incised wounds are disruptions of skin integrity that require effective treatment to accelerate healing. Cinnamon (Cinnamomum burmanii), rich in secondary metabolites such as eugenol, cinnamaldehyde, and flavonoids, is known for its potential as an anti- inflammatory, antioxidant, and antibacterial agent. This study aims to evaluate the effectiveness of cinnamon extract ointment in healing incised wounds in Wistar rats. This experimental study used a post-test only control group design. A total of 30 Wistar rats were divided into five groups: a negative control (ointment base), a positive control (gentamicin ointment), and three treatment groups with cinnamon extract ointments at concentrations of 10%, 20%, and 40%. Observations of wound length and healing percentages were conducted over 14 days. Data were analyzed using the Kruskal-Wallis and Mann-Whitney tests. The results showed a significant reduction in wound length in the 40% cinnamon extract ointment group (19.6 mm) compared to the negative control (12.8 mm) and were close to the effectiveness of gentamicin ointment (20 mm). The highest wound healing percentage was also achieved in the 40% concentration group (98.2%), comparable to gentamicin ointment (100%). Cinnamon extract ointment at a concentration of 40% effectively accelerates the healing of incised wounds in Wistar rats, with effectiveness comparable to gentamicin ointment. Further research is needed to evaluate its safety and clinical potential.
Hubungan Hipertensi dengan Penurunan Glomerular Filtration Rate pada Pasien Gagal Ginjal Kronis Silaban, Wulantika; Tarigana, Elviyanti Br.; Simbolon, Boyke Marthin
Jurnal Pendidikan Indonesia Vol. 6 No. 12 (2025): Jurnal Pendidikan Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/japendi.v6i12.8978

Abstract

Gagal ginjal kronis (GGK) merupakan masalah kesehatan global dengan prevalensi yang terus meningkat. Hipertensi diidentifikasi sebagai salah satu faktor risiko utama terjadinya dan progresivitas GGK, dengan prevalensi mencapai 85-90% pada pasien GGK. Penurunan Glomerular Filtration Rate (GFR) merupakan indikator utama penurunan fungsi ginjal yang progresif. Penelitian ini bertujuan untuk menganalisis hubungan antara hipertensi dengan penurunan GFR pada pasien GGK di Rumah Sakit Khusus Ginjal Rasyida Medan. Penelitian ini menggunakan desain observasional analitik dengan pendekatan cross-sectional yang melibatkan 129 pasien GGK. Data dikumpulkan melalui rekam medis yang mencakup karakteristik demografis, status hipertensi, nilai GFR, dan komorbiditas lainnya. Analisis data dilakukan secara univariat dan bivariat menggunakan program SPSS. Dari 129 subjek penelitian, mayoritas adalah laki-laki (62,8%) dengan kelompok usia terbanyak 60-80 tahun (45,0%). Prevalensi hipertensi pada pasien GGK sangat tinggi mencapai 95,3%. Sebagian besar pasien berada pada stadium terminal G5 (67,4%). Diabetes melitus ditemukan pada 17,8% pasien. Analisis bivariat menunjukkan bahwa pada pasien dengan hipertensi, 82,2% berada pada stadium lanjut (G4-G5), mengonfirmasi hubungan yang kuat antara hipertensi dengan progresivitas GGK. Kelompok usia muda (25-42 tahun) menunjukkan proporsi tertinggi pada stadium terminal (88,9%), mengindikasikan progresivitas yang lebih cepat. Terdapat hubungan bidireksional antara hipertensi dan penurunan GFR pada pasien GGK. Hipertensi mempercepat penurunan fungsi ginjal melalui berbagai mekanisme patofisiologis, sementara penurunan fungsi ginjal memperburuk hipertensi, membentuk siklus yang saling memperkuat. Tingginya proporsi pasien pada stadium terminal menekankan pentingnya deteksi dini, kontrol tekanan darah yang optimal, dan penatalaksanaan komprehensif untuk memperlambat progresivitas GGK.
Efek Pemberian Ekstrak Daun Lidah Buaya (Aloe Vera) Terhadap Penyembuhan Luka Bakar Tikus Putih Jantan (Rattus Novergicus) Galur Wistar Simbolon, Boyke Marthin; Hutasoit, Maria Angelina Br; Tarigan , Elviyanti Br
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v11i1.63668

Abstract

Burn injuries are a major cause of morbidity and mortality worldwide, accounting for approximately 180,000 deaths annually. Conventional treatments for burns often cause side effects such as allergic reactions and antibiotic resistance. Aloe vera has been traditionally used as a natural remedy for burns due to its bioactive compounds. This study aims to investigate the effect of aloe vera leaf extract administration on burn wound healing in male Wistar rats (Rattus norvegicus). This experimental research employs a post-test only control group design with 12 rats divided into four groups: negative control, positive control (silver sulfadiazine), and two treatment groups receiving different doses of aloe vera extract. Second-degree burns were induced using a heated iron plate. Parameters observed include wound diameter, healing time, and histopathological analysis of skin tissue. Aloe vera leaf extract contains bioactive compounds such as vitamins A, C, E, flavonoids, saponins, and tannins that play roles in wound healing through anti-inflammatory, antibacterial activities, and collagen synthesis stimulation. This research is expected to provide scientific evidence regarding the effectiveness of aloe vera as a safe, affordable, and accessible natural treatment alternative for burns in the community.
Antidiabetic potential of andaliman: Histopathological and glycemic improvements in diabetic rats Simbolon, Boyke Marthin; Lina, Juliana; Saragih, Ayu Theresia; Bangun, Chrismas Gideon; Nasution, Muhammad Fauzi; Rosari, Anita; Dewani, Yunita; Syahputra, Imam; Silalahi, Todung Donald Aposan
Buletin Kedokteran & Kesehatan Prima Vol. 5 No. 1 (2026): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v5i1.7891

Abstract

Background: Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia and pancreatic dysfunction, particularly involving the Islets of Langerhans. Andaliman (Zanthoxylum acanthopodium) is a plant rich in flavonoids and antioxidants, which are believed to have antidiabetic effects. This study aimed to evaluate the effectiveness of the ethanol extract of Andaliman fruit on pancreatic histopathology in alloxan-induced diabetic rats. Methods: This study employed a true experimental design with a pre-test and post-test control group structure. Twenty-four male Wistar rats were randomly assigned to six groups: a normal control, a positive control (metformin 9 mg/kg), a diabetic control (alloxan 90 mg/kg), and three treatment groups induced with alloxan followed by administration of Andaliman extract at doses of 150, 250, and 350 mg/kg body weight, respectively. Treatments were administered for 14 days, after which blood glucose analysis (pre- and post-treatment) and pancreatic histopathological assessments were performed. Results: Statistical analysis revealed a significant reduction in blood glucose levels following treatment (p = 0.001). Histopathological examination showed that Andaliman extract ameliorated alloxan-induced damage to the Islets of Langerhans. The 350 mg/kg body weight dose resulted in the most pronounced tissue regeneration compared to the other treatment groups. Conclusion: The ethanol extract of Andaliman fruit effectively improves pancreatic histopathology and lowers blood glucose levels in diabetic rats.
Co-Authors Akrom, Thoriq Bangun, Chrismas Gideon Br Ginting, Masita Unjuk Chairul, Muhammad Dewani, Yunita Dhillon, JagRoshen Singh Herisa Putri Anggraini Herisa Putri Anggraini Hutasoit, Maria Angelina Br Immanuella Pinem Larisma Simanullang Lina, Juliana Mei Riauly Wira Meldawati Meldawati Molek, Molek Mual Kristian Sinaga Muhammad Chairul Nasution, Muhammad Fauzi Novita Dwi Febrianty Novita Dwi Febrianty Petri Lumban Gaol Raynard A.K., Panta Leon Riris Grace Aprilia Riyani Susan Bt. Hasan Riyani Susan Bt. Hasan Riyani Susan Bt. Hasan Rosari, Anita Saragih, Ayu Theresia Siburian, Tissa Priscillya Deabitha Br Silaban, Wulantika Sinaga, Stevani Rose Br Sionia Delaroza Doloksaribu Sitompul, Christian Michael Oloan Sri Lestari Ramadhani Nasution Sukma, Triza Via Syahputra, Imam Tarigan, Elviyanti Tarigana, Elviyanti Br. Todung Donald Aposan Silalahi Wijaya, Wendi Yohania Premita