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Weaning Difficulty in Patient with End Stage Renal Disease Acute with Respiratory Failure due to Pulmonary Edema and Pneumonia Bangun, Primta; Suwarman, Suwarman
Journal of Society Medicine Vol. 2 No. 2 (2023): February
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (365.731 KB) | DOI: 10.47353/jsocmed.v2i2.29

Abstract

Introduction: End Stage Renal Disease (ESRD) 5D patient have potential to respiratory failure due to excess fluid, thus increasing the incidence of repeated hospital admissions. Deaths were reported in about 15%– 30% cases, where 50%–60% of patients needed respiratory support with mechanical ventilation. About 30%– 40% of patients had complications in the weaning process from mechanical ventilation. Prolonged mechanical ventilation increased mortality and morbidity, the length of stay periods and costs. Case Report: This case report will discuss the difficult weaning from mechanical ventilation in patients with ESRD 5D who have respiratory failure due to edema pulmonary and pneumonia who were hospitalized at the Intensive Care Unit (ICU) of Hasan Sadikin Hospital - Bandung for 20 days Conclusion: Weaning difficulty due to accumulation positive fluid balance during hospitalization lead to longer use of mechanical ventilation and pulmonary infection get heavier. A positive cumulative fluid balance could be one factor of weaning difficulty
Sunscreen Effect of Andaliman Methanol Extract Nano Gel on The Amount of Melanin in Wistar Rats Exposed to UV-B Light Vera, Vera; Chiuman, Linda; Ginting, Chrismis Novalinda; Nasution, Atika Rimalda; Bangun, Chrismas Gideon; Bangun, Primta
Jurnal Kesehatan Vol 15 No 3 (2024): Jurnal Kesehatan
Publisher : Poltekkes Kemenkes Tanjung Karang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26630/jk.v15i3.4486

Abstract

Excessive exposure to UV-B rays can increase melanin production, potentially causing skin damage, making it necessary to prevent this through the use of natural-based sunscreens, such as nano gel from methanol extract of andaliman, to protect the skin from the harmful effects of UV-B radiation. This study aims to evaluate the sunscreen effect of andaliman methanol extract nanogel on the amount of melanin in Wistar rats exposed to UV-B light. The method used was a laboratory experimental study with a randomized posttest only with a control group design using mice as the research subjects. The results of the study showed that the SPF values of andaliman extract at concentrations of 2%, 3.5%, and 5% were 2.11, 2.49, and 2.45, respectively, which are considered low for sunscreen protection standards. Additionally, the amount of melanin obtained from each treatment group was also categorized as small, indicating that the andaliman extract in nano gel form did not significantly reduce melanin production in Wistar rats exposed to UV-B rays. In conclusion, there is no sunscreen effect of andaliman methanol extract nanogel on the amount of melanin in Wistar rats exposed to UV-B light. This could be due to factors such as the low SPF value, the lack of stability of the active ingredients in the nano gel, or the need for an increased dosage. The implications of these findings suggest the need for further research to optimize the formulation or explore other more effective ingredients in preventing melanin production caused by UV-B exposure.
Combination of Vitamin D and Vitamin E Against Bacterial Infections Bangun, Primta; Rusip, Gusbakti; Mutia, Maya Sari
JAI (Jurnal Anestesiologi Indonesia) Vol 17, No 2 (2025): JAI (Jurnal Anestesiologi Indonesia)
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v0i0.69122

Abstract

Bacterial infections are a significant health problem worldwide, caused by various microorganisms that can infect different parts of the human body. Bacteria are single-celled microorganisms that can be found in various environments, including in the human body, and most of them are harmless. However, some species of bacteria can cause serious infections and inflammation that require proper medical attention. Some examples of bacteria that cause infections include Streptococcus pneumoniae, Pseudomonas aeruginosa, Salmonella typhi, Vibrio cholerae, Mycobacterium tuberculosis, Escherichia coli, and Staphylococcus aureus. A sufficient vitamin D level in the body can enhance antimicrobial activity against various pathogens, including bacteria, viruses, and fungi. Vitamin E is known to be a powerful antioxidant and has a positive effect on the immune system. It plays a role in protecting immune cells from oxidative damage and enhancing the immune response to infection. The combination of vitamins D and E offers significant potential in the prevention and management of bacterial infections, as both contribute to improved immunological function through different and complementary mechanisms.
The Effect of Sleep Quality On The Grade Point Average of Medical Students At Prima Indonesia University Class of 2023 Sakthi, Yudhisthira; Bangun, Primta; Abrar Harahap, Alvin
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.459

Abstract

Background: Medical students are exposed to high academic demands, which often lead to poor sleep quality and may impact cognitive function and academic achievement. This study aimed to analyze the relationship between sleep quality and grade point average (GPA) among medical students at Prima Indonesia University, class of 2023. Methods: A quantitative analytic approach with a cross-sectional design was used. The population included all active students from the 2023 cohort, with 162 respondents selected by simple random sampling. Sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI), and GPA data were obtained from official academic records. Data analysis involved univariate and bivariate statistics, with normality tested using Kolmogorov–Smirnov and correlation assessed by Spearman's rank test. Results: The majority of students (63.6%) had poor sleep quality (PSQI > 5), and the average GPA was 3.29. Spearman analysis showed a moderate negative correlation (rₛ = –0.505, p < 0.05) between sleep quality and GPA, indicating that poorer sleep quality was associated with lower academic achievement. Conclusion: Poor sleep quality significantly affects academic performance in medical students, highlighting the need for sleep hygiene education and time management interventions.
Inflammatory Marker Profile of Sepsis Patients at Royal Prima General Hospital Lenny; Bangun, Primta; Harahap, Alvin Abrar
Jurnal Penelitian Pendidikan IPA Vol 11 No 10 (2025): October
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i10.12745

Abstract

Sepsis is a serious complication that remains a leading cause of death worldwide, especially among young children and the elderly. Delayed diagnosis remains a major challenge, highlighting the need to develop accurate diagnostic modalities, including inflammatory markers derived from routine blood counts. This study aimed to describe the profile of inflammatory markers in sepsis patients at Rumah Sakit Umum Royal Prima Medan in 2024. This observational study employed a cross-sectional design, analyzing 81 medical records of sepsis patients from Royal Prima General Hospital in 2024, selected using simple random sampling. The variables measured included socio-demographic characteristics (age and sex), leukocyte profile (total leukocyte count, eosinophils, basophils, neutrophils, lymphocytes, and monocytes), and inflammatory indices (NLR, PLR, PNR, LMR, and NLPR). Most sepsis patients were male (50.6%) in the early elderly age group (33.3%), with median leukocyte counts of 17,350 cells/µL, neutrophils at 14,660 cells/µL, and lymphocytes at 1,279 cells/µL. The inflammatory marker indices showed trends of NLR 13.21, PLR 290.74, LMR 1.30, PNR 21.50, and NLPR 0.004. These results support the potential of routine blood inflammatory markers as indicators for sepsis progression.
Hubungan World Federation of Neurosurgical Societies (WFNS) Subarachnoid Hemorrhage (SAH) Grading Scale dan Mortalitas Pada Pasien Cedera Kepala dengan Perdarahan Subaraknoid di RS Royal Prima Medan Damanik, Agnes Marwaty; Harahap, Alvin Abrar; Bangun, Primta
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i11.62394

Abstract

Head injuries are one of the leading causes of morbidity and mortality in the world, with Subarachnoid Hemorrhage (SAH) being one of the most frequent complications that can increase the risk of death. The World Federation of Neurosurgical Societies (WFNS) Subarachnoid Hemorrhage (SAH) Grading Scale is used to assess the severity of SAH patients and predict their prognosis. This study aims to determine the relationship between WFNS SAH Grading Scale and mortality in head injury patients with SAH at Royal Prima Hospital Medan. The research method used an analytical observational approach with a cross-sectional design. The research sample amounted to 47 patients who met the inclusion criteria, using medical record data for the period January 2023 to August 2025. Data analysis was carried out using the Chi-Square test. The results showed that the majority of patients were in Grade I (38.3%) and Grade IV (27.7%), with a mortality rate of 23.4%. Statistical tests showed a value of p = 0.001 which means that there is a significant relationship between the WFNS SAH Grading Scale and the mortality of SAH patients. The lower the patient awareness level (GCS), the higher the risk of death. This study emphasizes the importance of using the WFNS SAH Grading Scale in assessing prognosis and determining the priority management of SAH patients in hospitals.
Hubungan Antara Skor Intracerebral Hemorragahe (ICH) dengan Mortalitas Pasien Perdarahan Intracerebral di RSU Royal Prima Medan Sari, Dian Puspita; Harahap, Alvin Abrar; Bangun, Primta
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i11.62527

Abstract

Intracerebral hemorrhage (ICH) is a form of hemorrhagic stroke with a high mortality rate. Assessment of severity using the ICH score is crucial for predicting prognosis and determining patient treatment priorities in hospitals. This study aims to determine the distribution of ICH patients based on the Glasgow Coma Scale (GCS) score, ICH volume, the presence of intraventricular hemorrhage (IVH), age, and location of the hemorrhage, and to analyze the relationship between ICH scores and patient mortality at Royal Prima Medan Hospital. This study used an observational-analytical design with a cross-sectional approach. The study population was all patients diagnosed with ICH during the study period, while a sample of 96 patients was obtained using the Lameshow formula. Data were collected through medical records and analyzed univariately and bivariately using the Chi-Square test. The results showed that most patients had a mild GCS score (53.1%), mild ICH volume (33.3%), and no intraventricular hemorrhage (52.1%). The largest age group was >60 years (56.3%), with the most common bleeding location being the right parietal (13.5%). The mortality rate reached 50%. Statistical tests showed no significant association between ICH score and mortality (p = 0.101), although clinically there was a trend towards an increased risk of death as the ICH score increased. Most patients presented with mild clinical conditions, but mortality remained high in more severe ICH scores. This study recommends improved early detection, more comprehensive radiological recording, and routine application of the ICH score as a prognostic tool in the management of patients with intracerebral hemorrhage.