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FORMULATION SALEP FENNEL LEAVES EXTRAC (Feoniculum vulgare Mill) WITH SALEP HIDROKARBON BASE VARIATION (VASELIN ALBUM) AND WATER BASE (PEG 6000) ON Staphylococcus aureus Riris Nurul Hidayah; Beta Ria Erika Marita Dellima; Mitta Aninjaya
STIKES DUTAGAMA KLATEN Vol 9 No 2 (2017): JURNAL ILMU KESEHATAN STIKES DUTA GAMA KLATEN
Publisher : STIKES DUTAGAMA KLATEN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.5737/v9i2.310

Abstract

Background: Fennel leaves (Feoniculum vulgare Mill) has potential as a medicine. The content of polyphenols, saponins, essential oils, and flavonoids found in the leaves show antibacterial effects. Fennel leaf extract is more perfect when formulated in ointment form. The use of ointment may allow direct contact with the skin. Objective: The objective of this research was to know the antibacterial activity and physical characteristic of fennel leaves extract (Feoniculum vulgare Mill) as inhibitor of Staphylococcus aureus. Research Method: This research is an experimental research by using One Group Pretest Posttest method. Fennel leaf extract (Feoniculum vulgare Mill) was obtained by maceration for 5 days. Furthermore fennel leaf extract identified active compounds contained therein. Then fennel leaf extract at concentrations of 20%, 25%, 30%, 35%, and 40% were tested for antibacterial activity of Staphylococcus aureus. Fennel leaf extract of 40% concentration is formulated in an ointment preparation with a hydrocarbon base (vaseline album) and water soluble base (PEG 6000). Testing of antibacterial activity using Staphylococcus aureus and physical properties of ointment. Testing of antibacterial activity using Staphylococcus aureus with agar diffusion method with sunuran technique, while for Tests physical properties of ointment include organoleptic test, homogeneity test, scattering, adhesion, power protection test, pH test. The data obtained were analyzed by Anova test statistic and Kruskal Wallis test. Result: The result of identification of active compound of fennel leaf extract have flavonoids, polyphenols, saponins. The base salt of hydrocarbon (vaseline album) and water soluble base (PEG 6000) showed that the spread of both ointment base did not show any significant difference and adhesion showed significant difference. The antibacterial activity of the hydrocarbon base ointment (vaseline album) and the water soluble base (PEG 6000) has a significant difference. Conclusion: The base used in this study has an effect on the physical quality of fennel leaf extract. This is seen from the scattering power value and the attachment power of both formulations. An ointment preparation with a hydrocarbon base (vaseline album) and a water soluble base (PEG 6000) affects the effectiveness of antibacterial ointment.
FORMULASI DAN EVALUASI SEDIAAN GEL INFUSA DAUN KELOR (Moringa oleifera Lam.) Beta Ria Erika Marita Dellima
JURNAL ILMU KESEHATAN BHAKTI SETYA MEDIKA Vol. 7 No. 1 (2022): Jurnal Ilmu Kesehatan Bhakti Setya Medika
Publisher : Politeknik Kesehatan Bhakti Setya Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (204.839 KB) | DOI: 10.56727/bsm.v7i1.79

Abstract

Kelor (Moringa oleifera Lam.) merupakan tanaman yang mempunyai banyak manfaat. Pemanfaata tanaman kelor menjadi bentuk sediaan farmasetis dapat memaksimalkan pemanfaatan daun kelor. Gel merupakan bentuk sediaan semi padat yang dapat diaplikasikan pada kulit. Sifat fisik sediaan gel dipengaruhi oleh eksipien (bahan tambahan dalam formulasi). Salah satu eksipien yang dapat mempengaruhi sifat fisik sediaan gel adalah gelling agent. Penggunaan HPMC sebagai gelling agent dapat menghasilkan cairan yang lebih jernih, netral, tidak berwarna, tidak berasa, menghasilkan gel dengan viskositas yang baik dalam penyimpanan jangka lama, tidak beracun dan tidak mengiritasi kulit. Daun kelor diekstraksi menggunakan metode infundasi. Infusa daun kelor diidentifikasi kandungan fitokimianya. Infusa daun kelor diformulasikan dengan HPMC sebagai gelling agent dalam berbagai konsentrasi 2,5 %, 5% dan 7,5% membentuk sediaan gel. Gel yang dihasilkan kemudian dievaluasi sifat fisik sediaan yang meliputi : uji organoleptis, uji homogenitas, uji pH, uji daya sebar dan uji daya lekat, yang dibandingkan dengan nilai standar parameter fisik sediaan gel. Hasil penelitian menunjukkan bahwa infusa daun kelor mengandung senyawa fitokimia : vitamin C, alkaloid, triterpenoid, saponin dan polifenol. Dari ketiga formula gel infusa daun kelor, formula II dengan konsentrasi gelling agent HPMC 5% memberikan hasil paling baik dan memenuhi nilai standar parameter fisik sediaan gel. Kata kunci : daun kelor, infusa, gelling agent
PENENTUAN KADAR KAFEIN DALAM BUNGA, BIJI, KULIT BUAH DAN DAUN KOPI ARABIKA (Coffea arabica) WONOLELO MENGGUNAKAN SPEKTROFOTOMETER UV Putri, Mega; Beta Ria Erika Marita Dellima
JURNAL FARMASI DAN KESEHATAN INDONESIA Vol. 3 No. 2 (2023): Jurnal Farmasi dan Kesehatan Indonesia
Publisher : Universitas Kristen Immanuel

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61179/jfki.v3i2.413

Abstract

Arabica coffee is a type of coffee that is widely cultivated in Indonesia. Caffeine is one of the secondary metabolites contained in coffee with various biological benefits. Caffeine belongs to the class of alkaloids of the methylxanthine group. Caffeine is distributed in different parts of the coffee plant in the leaves, cotyledons and flowers. Various studies have proven that the caffeine content in each part of the coffee plant has varying levels. This study aims to determine which part of the Arabica coffee plant comes from Wonolelo, Temanggung with the highest caffeine content. Powder of flowers, leaves, seeds and fruit skins of Arabica coffee were extracted with distilled water and then extracted liquid-liquid with chloroform, the chloroform fraction obtained was evaporated to form crystals containing caffeine. The results were analyzed quantitatively by UV spectrophotometry. The absorbance results were obtained from UV spectrophotometric readings, then the caffeine content in the sample was calculated and analyzed using SPSS software. Quantitative test stated that the highest to the lowest caffeine content were fruit peels of 3.232%, seeds (0.771%), flowers (0.509%), and leaves (0.24%). The results of this study are different compared to previous studies. This can occur due to differences in extraction methods, sample age, roasting conditions, grinding degree, geographical origin, such as growing locations at different altitudes, soil types, rainfall, harvest time, and intensity of exposure to sunlight.
UJI EFEKTIVITAS SEDIAAN GEL EKSTRAK ANGUR LAUT (Caulerpa racemosa) TERHADAP BAKTERI Staphylococcus aureus PENYEBAB JERAWAT: Intan Meilani Loni, Beta Ria Erika Marita Dellima, Eni Kartika Sari loni, intanmeilani; Beta Ria Erika Marita Dellima; Eni Kartika Sari
JURNAL FARMASI DAN KESEHATAN INDONESIA Vol. 3 No. 2 (2023): Jurnal Farmasi dan Kesehatan Indonesia
Publisher : Universitas Kristen Immanuel

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61179/jfki.v3i2.471

Abstract

ABSTRAK Ekstrak etanol anggur laut memiliki aktivitas antibakteri terhadap Staphylococcus aureus yang merupakan salah satu bakteri penyebab jerawat. Oleh karena itu, untuk mengetahui efektivitas kandungan senyawa aktif ekstrak etanol anggur laut yang berpotensi sebagai antibakteri, maka ekstrak etanol anggur laut diformulasikan dalam sediaan gel dengan gelling agent HPMC. Penelitian ini bertujuan untuk mengetahui pengaruh variasi konsentrasi ekstrak etanol anggur laut (Caulerpa racemosa) terhadap sifat fisik sediaan gel dan aktivitas antibakteri Staphylococcus aureus. Penelitian ini bersifat eksperimental dengan tahapan meliputi pembuatan ekstrak etanol anggur laut, skrining fitokimia, pembuatan gel ekstrak etanol anggur laut (Caulerpa racemosa) menggunakan gelling agent HPMC dengan konsentrasi 20%, 25%, 30% dan uji evaluasi sifat fisik sediaan. Selain itu, dilakukan uji aktivitas antibakteri terhadap Staphylococcus aureus. Pengamatan aktivitas antibakteri dilakukan dengan mengukur diameter zona hambat yang terbentuk di sekitar cakram. Data yang didapatkan berupa hasil sifat fisik dan zona hambat antibakteri yang dianalisis statistik dengan uji One Way ANOVA. Hasil penelitian ini menunjukkan bahwa gel ekstrak etanol anggur laut (Caulerpa racemosa) memenuhi syarat uji organoleptik, homogenitas, pH, daya sebar dan daya lekat. Selain itu, variasi konsentrasi ekstrak etanol anggur laut (Caulerpa racemosa) dalam sediaan gel mempengaruhi aktivitas antibakteri Staphylococcus aureus dengan hasil zona hambat formulasi 1 sebesar 4,36 mm (lemah), formulasi II sebesar 5,68 mm (sedang) dan formulasi III sebesar 8,05 mm (sedang). ABSTRACT Sea grape ethanol extract has antibacterial activity against Staphylococcus aureus, which is one of the bacteria that cause acne. Therefore, to determine the effectiveness of the active compound content of sea grape ethanol extract which has potential as an antibacterial, sea grape ethanol extract is formulated in gel preparations with HPMC gelling agent. This study aims to determine the effect of variation in concentration of ethanol extract of sea grape (Caulerpa racemosa) on the physical properties of gel preparations and antibacterial activity of Staphylococcus aureus. This research is experimental with stages including the preparation of ethanol extract of sea grape, phytochemical screening, gel preparation of ethanol extract of sea grape (Caulerpa racemosa) using HPMC gelling agent with concentrations of 20%, 25%, 30% and evaluation test of physical properties of the preparation. In addition, antibacterial activity test was conducted against Staphylococcus aureus. Observation of antibacterial activity was carried out by measuring the diameter of the inhibition zone formed around the disk. The data obtained in the form of results of physical properties and antibacterial inhibition zone were statistically analyzed with One Way ANOVA test. The results of this study indicate that sea grape (Caulerpa racemosa) ethanol extract gel meets the requirements of organoleptic, homogeneity, pH, spreadability and stickiness tests. In addition, variations in the concentration of ethanol extract of sea grape (Caulerpa racemosa) in gel preparations affect the antibacterial activity of Staphylococcus aureus with the results of the inhibition zone of formulation 1 of 4.36 mm (weak), formulation II of 5.68 mm (medium) and formulation III of 8.05 mm (medium).
UJI AKTIVITAS ANTIINFLAMASI EKSTRAK ETANOL DAUN SERAI WANGI (Cymbopogon nardus L.) SECARA IN VITRO DENGAN METODE HRBC (Human Red Blood Cell) Sari, Eni Kartika; Anantarini, Ni Putu Dea; Dellima, Beta Ria Erika Marita
Kartika : Jurnal Ilmiah Farmasi Vol 9 No 1 (2024)
Publisher : Fakultas Farmasi Universitas Jenderal Achmad Yani, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/kjif.v9i1.636

Abstract

Penggunaan jangka panjang dari obat steroid dan non steroid dalam mengobati inflamasi dapat memberikan efek samping yang merugikan. Daun serai wangi (Cymbopogon nardus L.) mengandung senyawa kimia flavonoid, alkaloid, tanin, saponin, steroid dan minyak atsiri yang bermanfaat sebagai antiinflamasi. Tujuan dilakukannya penelitian ini yaitu untuk mengetahui aktivitas antiinflamasi dari ekstrak etanol daun serai wangi dan untuk mengetahui pengaruh konsentrasi ekstrak etanol daun serai wangi terhadap aktivitas antiinflamasi. Uji aktivitas antiinflamasi ekstrak etanol daun serai wangi dilakukan secara in vitro dilihat berdasarkan pengaruhnya terhadap stabilitas membran sel darah merah menggunakan metode HRBC dengan darah yang dirusak larutan hipotonik sebagai media uji. Hasil penelitian menunjukkan bahwa ekstrak etanol daun serai wangi mempunyai efek antiinflamasi dari kemampuannya menjaga stabilitas sel darah merah, dimana semakin tinggi konsentrasi maka % stabilitas sel darah merah semakin besar pula. Nilai IC50 ekstrak etanol daun serai wangi dan aspirin secara berturut-turut adalah sebesar 9,302 ppm dan 15,070 ppm. Nilai IC50 ekstrak etanol daun serai wangi dan aspirin masuk ke dalam golongan aktivitas antiinflamasi sangat aktif dikarenakan nilai IC50 kurang dari 50 ppm. Hal ini menunjukkan bahwa aktivitas antiinflamasi ekstrak etanol daun serai wangi lebih tinggi dibandingkan aspirin sehingga berpotensi untuk dikembangkan sebagai agen antiinflamasi. Kata kunci: antiinflamasi, daun serai wangi, metode HRBC.   Abstract Long-term use of steroid and non-steroidal drugs in treating inflammation can have adverse side effects. Lemongrass (Cymbopogon nardus L.) leaves contain chemical compounds of flavonoids, alkaloids, tannins, saponins, steroids and essential oils which are useful as anti-inflammatories. The purpose of this study was to determine the anti-inflammatory activity of the ethanol extract of citronella leaves  and  to determine  how much influence the concentration of the ethanol extract of citronella leaves had on anti-inflammatory activity. The anti-inflammatory activity test of the ethanol extract of citronella leaves was carried out in vitro based on its effect on the stability of the red blood cell membrane using the HRBC method with blood damaged by a hypotonic solution as the test medium. The results showed that the ethanol extract of citronella leaves had an anti-inflammatory effect from its ability to maintain red blood cell stability, where the higher the concentration, the greater the % stability of red blood cells. The IC50 values of ethanol extract of citronella leaves and aspirin were 9.302 ppm and 15.070 ppm respectively. The IC50 value of ethanol extract of citronella leaves and aspirin is included in the class of very active anti-inflammatory activity because the IC50 value is less than 50 ppm. This shows that the anti-inflammatory activity of the ethanol extract of citronella leaves is higher than aspirin, so it has the potential to be developed as an anti-inflammatory agent. Keywords: anti-inflammatory, Cymbopogon nardus L., HRBC method.
UPAYA PENCEGAHAN STUNTING MELALUI EDUKASI DAN PENGOLAHAN PANGAN FUNGSIONAL BAGI WARGA DUSUN KRAPYAK KULON, PANGGUNGHARJO, SEWON, BANTUL Sari, Eni Kartika; Dellima, Beta Ria Erika Marita
Kumawula: Jurnal Pengabdian Kepada Masyarakat Vol 7, No 3 (2024): Kumawula: Jurnal Pengabdian Kepada Masyarakat
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/kumawula.v7i3.51496

Abstract

Stunting is a growth disorder, metabolic disorder, brain development disorder, and affects children's intelligence. Until now, the problem of stunting still occurs in the community, including in Krapyak Kulon, Panggungharjo Village, Sewon, Bantul. On the other hand, natural ingredients that are quite often found in Panggungharjo Village are lemongrass and ginger, the use of which is not optimal even though they are rich in active ingredients. Therefore, efforts are needed to increase the use value of these ingredients, which in this case are ingredients for making functional food to prevent stunting. This service aims to increase knowledge about the dangers of stunting and alternative functional food to prevent stunting in the form of Sang Kukis. Sang Kukis is a cookie made from natural ingredients rich in nutrients, namely banana flour, green bean extract, ginger and lemongrass with an attractive shape for children. Service activities are carried out offline or face-to-face through counseling and direct practice in making Sang Kukis. Community knowledge was measured through a pretest before the activity and a posttest after being given counseling and practical food making practices by the service team. Based on the results of the pretest and posttest which were attended by 22 participants, it can be stated that there was an increase in respondents' understanding of the definition of stunting from 45.45% to 68.18%, material on understanding the characteristics of stunting from 50% to 81.81%, causes of stunting from 45.45%. % to 90.90%, understanding of the dangers of stunting from 40.90% to 90.90% and understanding of functional food processing to prevent stunting from 31.81% to 86.36%. Based on this data, it can be concluded that community service activities can increase public understanding about the dangers of stunting and alternative foods to prevent stunting.Stunting merupakan gangguan pertumbuhan, gangguan metabolisme, gangguan perkembangan otak, hingga mempengaruhi kecerdasan anak. Sampai saat ini, permasalahan stunting masih terjadi pada masyarakat termasuk di Krapyak Kulon, Desa Panggungharjo, Sewon, Bantul.  Di sisi lain, bahan alam yang cukup banyak ditemukan di Desa Panggungharjo adalah serai dan jahe yang pemanfaatannya belum optimal meskipun kaya kandungan bahan aktif. Oleh karena itu, perlu upaya peningkatan nilai guna bahan tersebut yang dalam hal ini menjadi  bahan pembuatan pangan fungsional pencegah stunting. Pengabdian ini bertujuan untuk meningkatkan pengetahuan tentang bahaya stunting dan alternatif pangan fungsional pencegah stunting berupa Sang Kukis. Sang Kukis adalah kukis yang terbuat dari bahan alam kaya nutrisi yaitu tepung pisang, ekstrak kacang hijau, jahe, dan serai dengan bentuk yang menarik untuk anak. Kegiatan pengabdian dilaksanakan secara offline atau tatap muka melalui penyuluhan dan praktik secara langsung pembuatan Sang Kukis. Pengetahuan masyarakat diukur melalui pre test sebelum kegiatan dan post test setelah diberikan penyuluhan dan praktik pembuatan pangan fungsional oleh tim pengabdi. Berdasarkan hasil pre test dan post test yang diikuti oleh 22 peserta, dapat dinyatakan bahwa terjadi peningkatan pemahaman responden tentang definisi stunting dari 45,45% menjadi 68,18%, materi pemahaman ciri stunting dari 50% menjadi 81,81%, penyebab stunting dari 45,45% menjadi 90,90%,  pemahaman bahaya stunting dari 40,90% menjadi 90,90% serta mengerti pengolahan pangan fungsional pencegah stunting dari 31,81%  menjadi 86,36%. Berdasarkan data tersebut dapat disimpulkan bahwa kegiatan pengabdian kepada masyarakat dapat meningkatkan pemahaman masyarakat tentang bahaya stunting dan alternatif makanan pencegah stunting.
Uji Aktivitas Antiinflamasi Ekstrak Etanol Daun Sereh Wangi (Cymbopogon nardus L.) Dengan Metode Denaturasi Protein Sari, Eni Kartika; Dellima, Beta Ria Erika Marita; Azizah, Fatimah Nur
Lumbung Farmasi: Jurnal Ilmu Kefarmasian Vol 6, No 1 (2025): Januari
Publisher : UNIVERSITAS MUHAMMADIYAH MATARAM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/lf.v6i1.19785

Abstract

Long-term use of steroid and non-steroidal antiinflammatory drugs (NSAIDs) will cause side effects such as liver damage, digestive disorders and other side effects. Therefore, alternative treatments are needed that utilize the potential of natural ingredients. Lemongrass leaves have active compounds of flavonoids, tannins, steroids, saponins and alkaloids which have the potential to act as antiinflammatory. This study aims to determine the antiinflammatory activity of ethanol extract of citronella leaves using the protein denaturation method. Bovine serum albumin (BSA) as protein for testing. The test was carried out in vitro based on its effect on the inhibition of protein breakdown using BSA as a test medium which was damaged by heating.The results showed that the ethanol extract of citronella leaves has antiinflammatory activity with its ability to inhibit protein breakdown, where the higher the concentration, the higher the % inhibition of inhibition of BSA protein damage. A % inhibition value of more than 20% can be said to have antiinflammatory activity. The IC50 value of the ethanol extract of citronella leaves is 19,608 ppm and diclofenac sodium is 29,124 ppm. The IC50 value of the ethanol extract of citronella leaves and diclofenac sodium is in the very active category because the IC50 value is less than 50 ppm. This indicates that the antiinflammatory activity of the ethanol extract of citronella leaves is higher than diclofenac sodium so that it has the potential to be used as an antiinflammatory agent.
UJI STABILITAS SIFAT FISIK GEL EKSTRAK KULIT BUAH KOPI DAN PENENTUAN KADAR VITAMIN C SERTA ANTOSIANIN: STABILITY TEST OF THE PHYSICAL PROPERTIES OF COFFEE FRUIT PEEL EXTRACT GEL AND DETERMINATION OF THE LEVELS OF ACTIVE COMPOUNDS Putri, Mega Karina; Dellima, Beta Ria Erika Marita; Sari, Eni Kartika
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol. 25 No. 1 (2025): Jurnal Kesehatan Bakti Tunas Husada Volume 25 Nomor 1 Tahun 2025
Publisher : LPPM Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v25i1.1444

Abstract

Kulit buah kopi merupakan salah satu bagian dari buah kopi yang dapat dimanfaatkan sebagai kosmetik herbal. Kulit buah kopi termasuk limbah yang dihasilkan dari proses pengolahan kopi dan belum dimanfaatkan secara optimal. Padahal kulit buah kopi mengandung senyawa vitamin C dan antosianin yang berfungsi sebagai antioksidan dan bermanfaat bagi kulit. Untuk mempermudah penggunaannya, kulit buah kopi dapat di ekstraksi dan diformulasikan menjadi suatu sediaan farmasi, salah satunya adalah gel. Penelitian ini bertujuan untuk formulasi sediaan gel ekstrak kulit buah kopi dan melakukan uji stabilitas sediaan tersebut. Selain itu, juga menentukan kadar vitamin C dan antosianin dari sediaan gel yang paling stabil. Penelitian ini dilakukan dengan metode eksperimental dengan tahapan : persiapan bahan, pembuatan ekstrak, pembuatan sediaan gel, uji stabilitas sifat fisik, analisis statistik, penentuan kadar vitamin C dan antosianin. Berdasarkan hasil uji stabilitas selama 3 bulan pada suhu ruang diketahui bahwa sediaan gel yang paling stabil adalah formula 4 dan formula 5. Formula 5 mempunyai kadar vitamin C dan antosianin tertinggi. Hal tersebut dikarenakan pada ekstrak 5 mengandung ekstrak kulit buah kopi tertinggi. Kadar vitamin C sediaan gel ekstrak kulit buah kopi sebanding dengan kadar vitamin C gel pembanding yang ada dipasaran. Sedangkan, kadar vitamin C sediaan gel ekstrak kulit buah kopi berbeda signifikan dengan kadar yang lebih tinggi dibandingkan vitamin C gel pembanding yang ada dipasaran.
Pemberdayaan Nasabah BWM Al Muna Berkah Mandiri, Bantul, Yogyakarta Dengan Pembuatan Bath Bomb Salt Putri, Mega Karina; Dellima, Beta Ria Erika Marita; Sari, Eni Kartika
Shihatuna : Jurnal Pengabdian Kesehatan Masyarakat Vol 5 No 1 (2025): Juni
Publisher : FKM UIN Sumatera Utara Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30829/shihatuna.v5i1.23653

Abstract

Bath bombs are an example of a bath salt product. Using bath bombs can help moisturize the skin and brighten it, as a relaxant, so it can help reduce stress, tension and fatigue suffered by the body. By making easily from these ingredients, a cosmetic product that is useful and has high economic value can be obtained. This service program is expected to provide knowledge and skills to housewives and young women who are among the customers of BWM Al Muna Berkah Mandiri about making bath bombs with affordable capital and can develop their business products. Material presentation activities by resource persons from the service team, namely: apt. Mega Karina Putri, M. Pharm. Sci., and continued with a training session on making bath bomb salt and questions and answers. Apart from that, a pre-test and post-test were also carried out to measure participants' understanding before and after the event. Based on the results of the pretest and posttest, it was concluded that there was an increase in participants' knowledge. Participants in the very good category experienced an increase of 12% and good there was an increase of 16%, while participants in the fair category experienced a decrease of 12% and poor there was a decrease of 16%. The training participants and participant representatives expressed their gratitude because this activity was very useful in providing participants with an understanding of the steps for making bath bomb salt
UJI STABILITAS SIFAT FISIK GEL EKSTRAK KULIT BUAH KOPI DAN PENENTUAN KADAR VITAMIN C SERTA ANTOSIANIN: STABILITY TEST OF THE PHYSICAL PROPERTIES OF COFFEE FRUIT PEEL EXTRACT GEL AND DETERMINATION OF THE LEVELS OF ACTIVE COMPOUNDS Putri, Mega Karina; Dellima, Beta Ria Erika Marita; Sari, Eni Kartika
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol 25 No 1 (2025): Jurnal Kesehatan Bakti Tunas Husada Volume 25 Nomor 1 Tahun 2025
Publisher : LPPM Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v25i1.1444

Abstract

Kulit buah kopi merupakan salah satu bagian dari buah kopi yang dapat dimanfaatkan sebagai kosmetik herbal. Kulit buah kopi termasuk limbah yang dihasilkan dari proses pengolahan kopi dan belum dimanfaatkan secara optimal. Padahal kulit buah kopi mengandung senyawa vitamin C dan antosianin yang berfungsi sebagai antioksidan dan bermanfaat bagi kulit. Untuk mempermudah penggunaannya, kulit buah kopi dapat di ekstraksi dan diformulasikan menjadi suatu sediaan farmasi, salah satunya adalah gel. Penelitian ini bertujuan untuk formulasi sediaan gel ekstrak kulit buah kopi dan melakukan uji stabilitas sediaan tersebut. Selain itu, juga menentukan kadar vitamin C dan antosianin dari sediaan gel yang paling stabil. Penelitian ini dilakukan dengan metode eksperimental dengan tahapan : persiapan bahan, pembuatan ekstrak, pembuatan sediaan gel, uji stabilitas sifat fisik, analisis statistik, penentuan kadar vitamin C dan antosianin. Berdasarkan hasil uji stabilitas selama 3 bulan pada suhu ruang diketahui bahwa sediaan gel yang paling stabil adalah formula 4 dan formula 5. Formula 5 mempunyai kadar vitamin C dan antosianin tertinggi. Hal tersebut dikarenakan pada ekstrak 5 mengandung ekstrak kulit buah kopi tertinggi. Kadar vitamin C sediaan gel ekstrak kulit buah kopi sebanding dengan kadar vitamin C gel pembanding yang ada dipasaran. Sedangkan, kadar vitamin C sediaan gel ekstrak kulit buah kopi berbeda signifikan dengan kadar yang lebih tinggi dibandingkan vitamin C gel pembanding yang ada dipasaran.