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All Journal Paradigma: Jurnal Masalah Sosial, Politik, dan Kebijakan JURNAL SIMBOLIKA: Research and Learning in Communication Study Abdimas Talenta : Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Magister Pendidikan IPA Indonesian Journal of Pharmaceutical and Clinical Research International Journal Of Science, Technology & Management (IJSTM)
Sumaiyah
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Journal : International Journal Of Science, Technology

 1 
Testing Of The Cream Formula Turmina Right Extract Against The Inhibition Of The Development Of Melanoma Cells Vera, Vera Estefania Kaban; Jansen Silalahi; Sumaiyah
International Journal of Science, Technology & Management Vol. 3 No. 2 (2022): March 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i2.476

Abstract

Cancer is one of the biggest causes of death in the world and is still a health problem that still cannot be found the right treatment to overcome it. One of the cancers that cannot be ruled out is skin cancer, which occurs as a result of being exposed to direct sunlight for a long time and often without using skin protection or sunscreen. Cancer treatment that is currently being carried out is surgical therapy, chemotherapy which has adverse side effects for patients such as therapy that not only kills cancer cells but also healthy cells. The current therapy needed is the formulation of topical preparations that can be used to inhibit the growth of cancer cells. This study aims to make a cream preparation from turmeric extract to inhibit the growth of melanoma cells. This research was made experimentally by formulating turmeric rhizome extract into cream preparations at a concentration of 0.5%; 2.5% ; 5% ; 10% and 20% were tested against melanoma cell inhibition in vitro. Melanoma cell inhibition testing was carried out using the MTT Assay method by looking at the IC50 value of turmeric extract cream in inhibiting the growth of melanoma cells. The results showed that 20% turmeric rhizome extract cream was the formulation that gave the best IC50 value of 524.42 ± 5.2 g/mL.
Formulation and Evaluation of Liposome Moringa Oleifera Seed Oil (Moringa oleifera L.) as Anti-aging Hartini, Putri Tri; Sumaiyah; Hasibuan, Poppy Anjelisa Zaitun
International Journal of Science, Technology & Management Vol. 3 No. 4 (2022): July 2022
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v3i4.546

Abstract

Moringa oil is a natural vegetable oil obtained from the juice of the ripe kernels of the Moringa tree (Moringa oleifera L). Moringa seeds have an oil content of up to 40%, and have antioxidant activity with vitamin E content reaching 51% but have low stability. The purpose of this study was to find the best formulation as an anti-aging on liposome delivery system with a ratio of phosphatidylcholine soy lechitin and cholesterol. The method used is thin layer hydration (Thin Film Hydration). The results of the observation on the best formula are the 6th formula on organoleptic examination which is milky yellow in color, has a distinctive smell of lecithin and cholesterol and is in the form of a thick suspension, with a pH of 6.0, particle size 83.98nm using a particle size analyzer and entrapment efficiency of 96.8 % using a UV-Vis spectrophotometer.
Co-Authors Aminah Dalimunthe Anggi Wiraning Palupi Assyari Abdullah Desy Mairita Djendakita Purba Gulo, Jevon Three Kartika Hanum, Tengku Ismanelly Hartini, Putri Tri Hasibuan, Poppy Anjelisa Zaitun Jansen Silalahi JAYUS Karsono Latifha Padlani Maha, Hetty Lendora Masfria Muhammad Ramadhan Nazhifah, Nazhifah Nurfitriani Priwitaningrum, Dwi Lestari Santi Farmasari Situmorang, Sarah Melati Putri Vera, Vera Estefania Kaban Wiliantari, Selvia Zulfa Aulia Hasni