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The Relationship Between Anti-Tuberculosis Drug Therapy and Uric Acid and Creatinine Levels in Tuberculosis Patients in Kayong Utara District Selvianty, Selvianty; Indrawati, Ratih; Salim, Maulidiyah
MEDICA (International Medical Scientific Journal) Vol. 7 No. 2 (2025): MEDICA (Internasional Medical Scientific Journal)
Publisher : Borneo Scientific Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53770/medica.v7i2.513

Abstract

Pulmonary tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium tuberculosis. TB treatment involves five essential drugs: isoniazid, streptomycin, ethambutol, rifampicin, and pyrazinamide. Among these, pyrazinamide and ethambutol are known to potentially increase uric acid and creatinine levels as side effects. This study aimed to examine the relationship between anti-TB drug (OAT) therapy and levels of uric acid and creatinine in TB patients in Kayong Utara District. Using a cross-sectional design and purposive sampling, data were collected from 31 TB patients across three community health centers with the highest TB incidence. Results showed that 54.8% of patients had elevated uric acid levels, while 45.2% had normal levels. For creatinine, 93.5% had normal levels, and 6.5% had elevated levels. Chi-square analysis indicated a significant association between OAT therapy and uric acid levels (p = 0.045), but no significant relationship was found with creatinine levels (p = 1.000). These findings suggest that OAT therapy may affect uric acid levels in TB patients, highlighting the need for monitoring during treatment.  
Influence pH to Rate Anthocyanins Extract Senggani Fruit ( Melastoma malabathricum Auct, non Linn) Indrawati, Ratih; Jenny.R, Gervacia; Salim, Maulidiyah; Ihsan, Bagus Muhammad; Widiyantoro, Ari
Jurnal Penelitian Pendidikan IPA Vol 10 No 6 (2024): June
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i6.7267

Abstract

One of the plants that can be used as a natural dye is senggani fruit. This study aimed to determine the effect of acid pH on the anthocyanin levels of the senggani fruit extract. The method used in this study uses UV-Vis Spectrophotometry. The sample was senggani fruit extract, added with an acidic pH solution (1-6) with 3 repetitions for 18 samples. Based on the results of research that has been carried out, the average anthocyanin levels at pH 1 are 2.00% with a bright red color; pH 2 is 1.63% with a red-orange color, pH 3 is 1.45% with an orange color, pH 4 is 2.05 % with brownish red color, pH 5 is 1.38% with brownish orange color, and pH 6 is 1.11% with light brown color. Based on statistical tests using Simple Linear Regression, Ha was accepted so that it could be concluded that there was an effect of acid pH on the anthocyanin levels of the senggani fruit. Based on a study that has been done, it is known that the sourer the pH solution is, the taller the anthocyanin obtained. Matter happens Because absorbance is comparable with the rate of anthocyanin something sample.
PENYULUHAN PENGGUNAAN PEWARNA ALAMI DARI DAUN KELOR (Moringa oleifera) SEBAGAI SUMBER ANTIOKSIDAN PADA MAKANAN DALAM RANGKA MENINGKATKAN NILAI GIZI MASYARAKAT Ratnawaty, Gervacia Jenny; Indrawati, Ratih; Sungkawa, Hendra Budi
BUDIMAS : JURNAL PENGABDIAN MASYARAKAT Vol. 6 No. 1 (2024): BUDIMAS : Jurnal Pengabdian Masyarakat
Publisher : LPPM ITB AAS Indonesia Surakarta

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Abstract

Tanaman Kelor telah dikenal selama berabad-abad sebagai tanaman multi guna, padat nutrisi dan berkhasiat obat. Mengandung senyawa alami yang lebih banyak dan beragam dibanding jenis tanaman lainnya yang ada. Tanaman Kelor mengandung 46 anti oksidan kuat yang melindungi tubuh dari radikal bebas, mengandung 18 asam amino (8 diantaranya esensial) yang dibutuhkan tubuh untuk membangun sel-sel baru, 36 senyawa anti inflamasi, serta 90 nutrisi alami seperti vitamin dan mineral . Kelor merupakan bahan pangan yang kaya akan zat gizi makro dan mikro. Kandungan nilai gizi yang tinggi dalam daun kelor dapat dimanfaatkan untuk pemenuhan kebutuhan nutrisi pada ibu menyusui dan balita dalam masa pertumbuhan (Aminah et al, 2015). Pemberian daun kelor dapat meningkatkan Indeks Masa Tubuh (IMT) pada balita (Rahayu & Nurindahsari, 2018). Penelitian yang pernah dilakukan oleh Sari,(2019) menunjukkan bahwa penambahan tepung daun kelor yang lebih tinggi akan meningkatkan kadar abu, kadar protein dan kadar serat kasar pada tepung komposit. Selain itu daun kelor juga mengandung antioksidan yang tinggi yaitu pada bagian atas atau pucuk daun (SUGIANTO, 2016) . Metode pelaksanaan yang dilakukan adalah kunjungan ke lokasi mitra, demontrasi pelatihan pembuatan hasil olahan makanan menggunakan daun kelor, dan sosialisasi tentang kandungan gizi daun kelor di Desa Rasau Jaya Umum, Kabupaten Kubu Raya Kalimantan Barat.