Article Per Year (5 Year)
p-Index From 2021 - 2026
1.066
P-Index
This Author published in this journals
All Journal Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia eJournal Kedokteran Indonesia The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Indonesian Journal of Medical Chemistry and Bioinformatics
Sri Suryo Adiyanti, Sri Suryo
Departemen Patologi Klinik, Fakultas Kedokteran Universitas Indonesia, Rumah Sakit Umum Pusat Nasional Cipto Mangunkusumo, Jakarta
Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

Published : 5 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 5 Documents
Search

 1 
The Role of Neutrophil Lymphocyte Ratio , Vitamin D, and NGAL as Cardiovascular Disease Marker in Chronic Kidney Disease Sri Suryo Adiyanti; Yusra Yusra; Suzanna Immanuel; Diana Aulia; Fify Henrika; July Kumalawati
eJournal Kedokteran Indonesia Vol 9, No. 3 - Desember 2021
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (154.048 KB) | DOI: 10.23886/ejki.9.35.192-6

Abstract

Chronic kidney disease (CKD) patients have higher risk to develop cardiovascular disease (CVD) than non-CKD patients. Neutrophil lymphocyte ratio (NLR) in CKD patients reflects inflammation status and role as complementary prognostic marker to evaluate cardiovascular risk in stage 3 to 5 CKD. High prevalence of vitamin D deficiency commonly found in CKD patients, leads to endothelial dysfunction and increase inflammation. NGAL is used as renal injury biomarker but nowadays NGAL has been known plays important role in CVD pathophysiology. CVD identification in CKD patients is necessary to obtain CVD risk and to stratify mortality earlier in CKD patients. This study aimed to obtain the differences and continued to obtain cut off of NLR, vitamin D and NGAL in CKD patients undergoing hemodialysis (HD) with and without CVD if the differences was significantly. A cross-sectional study was conducted in dr. Cipto Mangunkusumo National Hospital Jakarta, in December- February 2020. Total subjects were 83, consists of two groups with and without the CVD. There were no significant differences of NLR and vitamin D in CKD patients undergoing hemodialysis (HD) with and without CVD. The significant difference was found only in NGAL with cut off 5.64 ng/ml. NLR was lower, meanwhile vitamin D and NGAL were higher in CKD patients undergoing HD with and without CVD.
The Role of Various Laboratory Parameters and Imaging Associated with Obstructive Jaundice in Cholangiocarcinoma Sri Suryo Adiyanti; Rustadi Sosrosumihardjo
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 15, No 1 (2014): VOLUME 15, NUMBER 1, April 2014
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (4782.815 KB) | DOI: 10.24871/151201457-62

Abstract

Cholangiocarcinoma is the second most common primary liver malignancy with a global increase ofincidence and mortality. The mean age at presentation is 50 years. Patients with cholangiocarcinoma usuallywill have symptoms of obstructive jaundice followed with supporting laboratory and imaging findings. Thepredominant clinical feature of extrahepatic cholangiocarcinoma is biliary obstruction resulting in jaundice; while intrahepatic cholangiocarcinoma causes symptoms of intrahepatic mass including abdominal pain in right upper quadrant and other tumor-related symptoms such as cachexia and malaise. The diagnosis and stagingof cholangiocarcinoma require multidisciplinary approaches including laboratory, radiological, endoscopicapproaches and analysis on pathology. This case report describes a patient with a cholangiocarcinoma based on results of endoscopic retrogradecholangiopancreatography (ERCP) imaging. In addition to a diagnosis tool, ERCP can also be a therapeuticmodality for placing stent to reduce symptoms of cholestasis. There were supporting laboratory findings suchas increased bilirubin level, alkaline phosphatase (ALP) and gamma glutamyltransferase (GGT) levels as wellas increased level of tumor markers such as carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9and cytological examination.Keywords: cholangiocarcinoma, jaundice, obstructive, ERCP ABSTRAKKolangiokarsinoma merupakan keganasan hati primer kedua yang paling umum, dimana insiden danmortalitasnya meningkat secara global. Usia rata-rata timbulnya gejala adalah 50 tahun. Pasien dengankolangiokarsinoma pada umumnya mengalami gejala ikterus obstruktif disertai dengan hasil laboratoriumdan pencitraan yang mendukung. Gambaran klinis yang predominan dari kolangiokarsinoma ekstrahepatik adalah obstruksi bilier yang menyebabkan ikterus, sedangkan kolangiokarsinoma intrahepatik menimbulkan gejala adanya massa intrahepatik yang menyebabkan nyeri kuadran kanan atas abdominal dan gejala terkaittumor lainnya yaitu kakeksia dan malaise. Diagnosis dan staging kolangiokarsinoma memerlukan pendekatanmultidisipliner antara lain laboratorium, radiologis, endoskopi dan analisis patologi.Pada kasus berikut ini seorang pasien didiagnosa kolangiokarsinoma yang ditegakkan berdasarkan pencitraanendoscopic retrograde cholangiopancreatography (ERCP). Selain untuk diagnosis, ERCP menjadi modalitasterapi dengan dilakukan pemasangan stent untuk mengurangi gejala kolestasis. Pemeriksaan laboratoriumyang mendukung antara lain peningkatan bilirubin, alkalin fosfat dan gamma glutamil transferase (GGT),peningkatan penanda tumor seperti carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9, dan pemeriksaan sitologi.Kata kunci: kolangiokarsinoma, ikterus, obstruktif, ERCP
A Comparative Study of PTS and Manual Transportation for Platelet Count and Aggregation Test Sri Suryo Adiyanti; Bernadette Elvina Setiadi
INDONESIAN JOURNAL OF CLINICAL PATHOLOGY AND MEDICAL LABORATORY Vol. 29 No. 2 (2023)
Publisher : Indonesian Association of Clinical Pathologist and Medical laboratory

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24293/ijcpml.v29i2.2010

Abstract

The transportation effect of the Pneumatic Tube System (PTS) on platelet activity remains controversial. This study aimed to analyze the effect of PTS in the platelet aggregation test in Dr. Cipto Mangunkusumo Hospital, Jakarta. This cross-sectional study was carried out in the Clinical Pathology Laboratory of Dr. Cipto Mangunkusumo Hospital (RSUPNCM) from March to April 2021. There were 50 subjects involved in this study, each of whom 6 sodium citrate blood tubes were extracted. Three tubes were sent through PTS while the rest were transported manually. All tubes were then tested for platelet count and platelet aggregation using ADP agonists of 1 uM, 5 uM, and 10 uM. There was a lower platelet count (p=0.046) and platelet aggregation in ADP 1 uM (p=0.037), ADP 5 uM (p <0.001), and ADP 10 uM (p <0.001) at PTS-transported samples. Eleven samples were interpreted distinctively as low platelet aggregation in PTS transportation became normal in manual delivery. Cohen’s Kappa value was 0.51 (p <0.001). A decreasing platelet count and platelet aggregation in PTS samples indicated that acceleration and deceleration during transportation could lead to platelet activation, thus resulting in a lower result after being added to an agonist. Cohen's Kappa test showed that manual transportation could not be replaced with PTS for the platelet aggregation test. Platelet count and platelet aggregation were found to be lower in PTS-transported samples. It was suggested to centralize specimen taking for platelet aggregation tests, thus manual transportation can be conducted more efficiently.
Prothrombin Time (PT), Activated Partial Thromboplastin Time (APTT), Fibrinogen, and D-dimer in Coronavirus Disease 2019 Outcome Atmaja, Fredy Wirya; Adiyanti, Sri Suryo; Kristanty, Diyah; Dwira, Surya; Kusmardi, Kusmardi
Indonesian Journal of Medical Chemistry and Bioinformatics Vol. 3, No. 1
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

COVID-19, caused by SARS-CoV-2 has been reported to be associated with coagulopathy and DIC. This study aimed to investigate the profiles and differences of PT, APTT, fibrinogen, and D-dimer in COVID- 19 outcome. This retrospective cohort was conducted at Central Laboratory Clinical Pathology Department of dr. Cipto Mangunkusumo Hospital from July – December 2020. Demographic, clinical, and laboratory data were extracted from EHR and compared between poor and good outcome. Ninety-seven subjects were confirmed positive COVID-19, 45 of whom (46.4%) were in poor outcome group, while 52 subjects (53.6%) were in good outcome group. Median of PT 11.0” (9.7-28.3), APTT 38.4” (23.9-121), fibrinogen 484.8 mg/dL (51.2-940.9), and D-dimer 1,800 µg/L (190-35,200). Longer PT, APTT, and higher D-dimer (p < 0.05), while lower fibrinogen (p > 0.05) was found in poor outcome group. There were significant differences of PT, APTT and D-dimer in COVID-19 outcome.
Sindrom Raynaud: Laporan Kasus Sanny Kusuma Sary; Sri Suryo Adiyanti
Majalah Kedokteran Indonesia Vol 74 No 1 (2024): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.74.1-2024-554

Abstract

Introduction: Raynaud’s phenomenon is a condition characterized by sudden discoloration of the skin on the fingers caused by vasospasm. It can occur either as a primary condition or secondary to other diseases, such as Sjogren’s syndrome. Laboratory tests play an essential role in diagnosing and treating Raynaud’s syndrome. Case Report: A 38-year-old woman with clinical Raynaud’s syndrome underwent Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) examinations, which resulted in prolonged values. The patient complained of pain and a black wound on the tips of the 2nd and 3rd fingers of the left hand. The patient was checked for PT, APTT, lupus anticoagulant (LA), antinuclear antibody (ANA), anticardiolipin antibody (ACA) IgG and IgM, Beta 2 GP IgG and IgM, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR) and ANA profile with fluctuating PT and APTT results, weak positive LA, indeterminate ACA IgG, fast ESR, increased CRP, ANA profile (++) Ro-52 recombinant.Discussion: Raynaud’s syndrome is a group of symptoms caused by vasospasm and is often associated with autoimmune diseases. The patient presented with typical complaints of Raynaud’s phenomenon and laboratory results of the ANA profile that support a diagnosis of Sjogren’s syndrome. Fluctuations in PT and APTT may be due to intravenous heparin therapy, warfarin, inflammatory conditions, or antiphospholipid antibodies.Conclusion: ANA profile results in patients corresponding to Sjogren’s syndrome, which underlies Raynaud’s syndrome. It is advisable to check mixing studies, liver synthesis function, and antiphospholipid antibodies with an interval of 12 weeks to look for other causes of prolonged PT and APTT.
Co-Authors Atmaja, Fredy Wirya Bernadette Elvina Setiadi Diana Aulia Fify Henrika, Fify Giantini, Astuti Indrasari, Nuri Dyah Kristanty, Diyah Kumalawati, July Kusmardi Nafisah Nafisah Nurhardini, Tammy Rustadi Sosrosumihardjo Rustadi Sosrosumihardjo Sanny Kusuma Sary Surya Dwira Suzanna Immanuel Timotius Alvonico Yudhistira Yudhistira YUSRA YUSRA Yusra Yusra Yusra, Yusra