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Relationship between Quality of Life and Nutritional Status on Chronic Kidney Disease Patients with Dialysis Type Dewi, Ratih Tri Kusuma; Putranto, Wachid; Susanto, Agung; Suseno, Aryo; Purwanto, Bambang; Mangesti, Rini Dwi; Giani, Maia Thalia; Septian, Muhammad Raditia
Jurnal Penyakit Dalam Indonesia Vol. 7, No. 1
Publisher : UI Scholars Hub

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Global prevalence and contributing factors of transplant renal artery stenosis in renal transplant recipients: A systematic review and meta-analysis Tamara, Fredo; Fajar, Jonny K.; Gersom, Camoya; Wicaksono, Ramadi S.; Tupamahu, Alvira R.; Huda, Fariz N.; Sari, Fitria R.; Dela, Jamaludin A.; Putri, Irawati E.; Sutrisno, Muhammad A.; Putra, Riyantono; Dwinata, Michael; Friatna, Yudha; Albaar, Thoha M.; Susanto, Agung; Dewi, Ratih TK.; Suseno, Aryo; Samsu, Nur
Narra J Vol. 4 No. 3 (2024): December 2024
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v4i3.1782

Abstract

Transplant renal artery stenosis (TRAS) is a serious complication of renal transplantation, with its prevalence and associated factors remaining inconclusive. The aim of this study was to assess the global prevalence and risk factors associated with TRAS incidence in renal transplant recipients. We conducted a meta-analysis by collecting data on the prevalence and factors associated with TRAS from articles in Scopus, Embase, and PubMed. The prevalence of TRAS was determined using a single-arm meta-analysis. The factors associated with TRAS were determined using Mantel-Haenszel analysis or inverse variance analysis. Out of 28,599 articles from the searches, 31 of them were included in the analysis. The global prevalence of TRAS was 6% among renal transplant recipients. Diabetes mellitus, hypertension, longer duration of dialysis before transplant, deceased donor, acute rejection, delayed graft function, longer cold ischemic time, and prolonged peak systolic velocity were associated with an increased risk of TRAS. Age, gender, peripheral artery disease (PAD) comorbidity, causes of end-stage renal disease (ESRD), previous dialysis modality, and cytomegalovirus infection were not associated with TRAS incidence. In conclusion, the global prevalence of TRAS in renal transplant recipients is relatively high, and some of the contributing factors to the development of TRAS are preventable. These findings could serve as a guideline for informing the management of TRAS in the future.
Effect of MgSO4 Administration on The Incidence of Acute Kidney Injury and Renal Function in Lung Cancer Patients Receiving Cisplatin Chemotherapy Lestari, Nastiti; Setiadji, Ana Rima; Suseno, Aryo
Jurnal Respirologi Indonesia Vol 45 No 4 (2025)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v45i4.843

Abstract

Background: Platinum-based chemotherapy is the most common lung cancer therapy currently performed with satisfactory results, but the use of platinum-based chemotherapy, such as cisplatin, can cause cisplatin-induced nephrotoxicity (CIN). MgSO4 is a substance that has been studied and is known to have a protective effect on the kidneys. This study aims to determine the effect of MgSO4 administration on the incidence of CIN in lung cancer chemotherapy patients receiving cisplatin chemotherapy. Methods: This was a quasi-experimental study with a pre-test and post-test control group design. The study group received intravenous MgSO4 20 mEq, and the control group received standard therapy without MgSO4. The incidence of CIN was assessed based on the incidence of acute kidney injury (AKI) and renal function measured by the estimated glomerulus filtration rate (eGFR). Results: The incidence of AKI in the treatment group was 6.67%, whereas the control group had no incidence of AKI (P=0.32). Renal function (eGFR) showed no significant difference between the treatment and control groups (P=0.86), although both groups exhibited improved renal function post-chemotherapy. Conclusion: MgSO4 administration does not affect the incidence of AKI and renal function of lung cancer patients receiving cisplatin chemotherapy.