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Optimization of Energy for Proton Therapy with Pencil Beam Collimator Model in Craniopharyngioma Tumor Using MCNP6 Code Putri, Weni Antari; Riyatun, Riyatun; Darmanto, Darmanto; Suharyana, Suharyana; Arianto, Fajar
Journal of Physics and Its Applications Vol 6, No 1 (2023): November 2023
Publisher : Diponegoro University Semarang Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jpa.v6i1.18100

Abstract

Computational simulations of proton therapy with a pencil beam collimator for craniopharyngioma have been done using MCNP6. A pencil beam was radiated towards cube shaped tumor cells in size 1.2 cm, located at a 5.4 cm depth from the surface of the scalp. A 0.1 cm pencil beam was radiated from the left 19.6 cm from the scalp. The cube of tumor cell is divided into the front layer, middle layer, and back layer. Each layer of the tumor cell is divided into 9 cubicles, thus there are 27 cubicles. Using various energy from 108 MeV to 115 MeV and various intensity of energy for each irradiation, it produces the dose for each cubicle in unit MeV/gram per proton. The best isodoses occurred in 5 variations of energy which is 108.2; 111.2; 113.4; 114.7 and 115 MeV. The healthy organ that received the largest dose of the proton is the brain, it is (7.38±0.01)×10-2 MeV/gram per proton, or only 0.412% compared to the tumor cell dose.
Performance and Selection of Mutant Black Rice with High Lignin Handayani, Rizky; Nandariyah, Nandariyah; Parjanto, Parjanto; Riyatun, Riyatun; Sutarno, Sutarno
Agro Bali : Agricultural Journal Vol 7, No 3 (2024)
Publisher : Universitas Panji Sakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37637/ab.v7i3.1927

Abstract

Eating black rice can avoid the risk, reduce insulin in the body, bind free radicals, and reduce weight. However, black rice still has disadvantages, like long life, tall stems, less resistance to pests and diseases, and low yields. Activities were carried out from August 2023 to November 2023 in Pakahan Village, Jogonalan, Klaten. The planting materials used were selected M3 mutant black rice seeds irradiated with 200 Gy gamma rays and Cempo Ireng black rice as a control plant. Planting used a randomized complete block design without replication with the pedigree selection method. The parameters measured were harvest age, plant height, productive tillers, and seed weight per plant. Descriptive analysis was used and a 5% level T test was carried out to compare the characteristics of the M4 genotype with the control (without irradiation). The research results showed that 12 individuals containing high lignin were selected which could be further developed for the next generation. 
Lanthanum-substituted Cobalt Ferrite Established by the Co-precipitation Process: Annealing Temperature Adjustment of Structural, Magnetic, and Dye Removal Characteristics Rahmawati, Ramadona; Musadewi, Adiana; Prasetya, Nurdiyantoro Putra; Suharno, Suharno; Budiawanti, Sri; Rahardjo, Dwi Teguh; Riyatun, Riyatun; Utari, Utari; Iriani, Yofentina; Nuryani, Nuryani; Purnama, Budi
Bulletin of Chemical Reaction Engineering & Catalysis 2023: BCREC Volume 18 Issue 4 Year 2023 (December 2023)
Publisher : Masyarakat Katalis Indonesia - Indonesian Catalyst Society (MKICS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.9767/bcrec.19638

Abstract

Co-precipitation process was used for the synthesis of lanthanum-substituted cobalt ferrite nanoparticles at several annealing temperatures (Ta), i.e., 200 °C, 300 °C, and 400 °C, for 5 h. XRD spectral depicted that the produced nanoparticles sample indicates a single phase of fcc inverse spinel conforming to ICDD No 22-1086. The crystallite size (D) calculation at the strongest peaks shows the increase in enhancing the Ta i.e., 18.99 nm, 19.90 nm, and 23.21 nm for 200 °C, 300 °C, and 400 °C, respectively. The FTIR results showed absorption band at the tetrahedral site, v1 ~575 cm−1 and the octahedral site, v2 ~474 cm−1. The absorption bands indicate that the lanthanum ions have successfully replaced the Fe3+ cations in the original cobalt ferrite structure. According to the hysteresis loop, the coercive field's (HC) magnitude falls from 700 Oe down to 550 Oe as Ta increases. This result is consistent with the anisotropy constant which decreased from 0.77×104 erg/cm3 to 0.56×104 erg/cm3. The obtained nanoparticles also showed superior performance (much larger than 95%) for dye removal of Congo red. Copyright © 2023 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
Effect of sodium oxide (Na2O) glass modifier on physical properties and gamma shielding in tellurite glass systems TeO2-ZnO-PbO-Bi2O3 (TZPB) Marzuki, Ahmad; Ariyanti, Selvina; Alvyanti, Frisca Aulia; Kasy, Fransisca Indraningsih; Fausta, Devara Ega; Riyatun, Riyatun; Sari, Arum Luvita
Journal of Physics: Theories and Applications Vol 7, No 1 (2023): Journal of Physics: Theories and Applications
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jphystheor-appl.v7i1.71795

Abstract

TZPB glasses with the composition 55TeO2-(41-x)ZnO-2Bi2O3-2PbO-xNa2O (x= 2; 2.5; 3; 3.5 mol%) have been fabricated and characterized to determine the physical properties and gamma radiation shielding parameters. The method of glass fabrication is melt quenching with the holding temperature at 900˚C for 30 minutes and the annealing temperature at 256˚C for 6 hours. The result of the characterization of the density and gamma shielding parameters was calculated using Phy-X PSD software. The glass density was measured using Archimedes's principle and showed a decrease from 5.79 to 5.73 g/cm3. The molar volume increased from 23.3 to 23.6 g/mol with the addition of Na2O concentration. Gamma radiation shielding parameters, LAC, MAC, MFP, HVL, and TVL simulated with the energy range were 10-3-105 MeV. The results of Phy-X/PSD software showed an increasing MAC, MFP, HVL, and TVL and decreasing in LAC with an increase in Na2O concentration.
Analisis Distribusi Dosis Serap Glioma Cerebri pada Gamma Knife dengan Simulasi MCNP6 Afifah, S.A.P.S.; Suharyana, Suharyana; Riyatun, Riyatun; Darmanto, Darmanto
Prosiding SNFA (Seminar Nasional Fisika dan Aplikasinya) 2021: Prosiding SNFA (Seminar Nasional Fisika dan Aplikasinya) 2021
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/prosidingsnfa.v5i0.71816

Abstract

Abstract. A brain tumor (Glioma Cerebri) is an abnormal growth and division of cells in the skull cavity. There are many tumor therapies, namely surgery, chemotherapy, and radiotherapy. Gamma knife is effective radiotherapy in brain tumours and requires a careful Treatment Planning System (TPS) regarding the absorbed dose. This study reports the results of simulations using software MCNP6 by modelling tumour cells in the shape of a ball with a diameter of 1 cm and located in the centre of the brain. The source of the -radiation is the isotope Co-60, emitting from the source point with isotropically, the distance from the source to the phantom surface (SSD) is 40.1 cm. The phantom is a head and neck containing material that makes up soft tissue and bone. The proton beam guiding collimator has a size according to the helmet collimator diameter, namely 1.25 mm, 2.5 mm, 4.25 mm, and 5.3 mm. The simulation resulted in the absorbed doses in tumour cells (6.17±0.37) mGy, (10.73±0.45) mGy, (10.87±0.45) mGy, and (10.89±0.45 ) mGy. The amount of scattered dose outside the tumour cells has been measured, and the enormous value is in the brain organ with a hefty dose (25.60±1.96) mGy, (122.29±1.41) mGy, (398.20±7.75) mGy, and (597.65±6.18) mGy. Evaluation of the organ dissipated dose is in the safe category. The total irradiation time required is (40.5±2.4) minutes, (23.4±1.0) minutes, (23.0±1.0) minutes, and (22.9±0.9) minutes.Abstrak: Tumor otak (Glioma Cerebri) merupakan suatu pertumbuhan dan pembelahan sel yang tidak wajar pada rongga tengkorak. Terdapat banyak terapi tumor yaitu pembedahan, kemoterapi, dan radioterapi. Gamma knife merupakan radioterapi yang efektif pada tumor otak dan memerlukan Treatment Planning System (TPS) yang teliti terkait dosis serap. Penelitian ini melaporkan hasil simulasi dengan software MCNP6, dengan memodelkan sel tumor berbentuk bola berdiameter 1 cm dan terletak pada pusat otak. Sumber radiasi-γ berasal dari isotop Co-60, memancar dari sumber titik dengan secara isotrop, jarak sumber ke permukaan fantom (SSD) 40,1 cm. Fantom adalah kepala dan leher berisi material penyusun jaringan lunak dan tulang. Kolimator pengarah berkas proton memiliki ukuran sesuai dengan diameter kolimator helm yaitu 1,25 mm, 2,5 mm, 4,25 mm, dan 5,3 mm. Simulasi menghasilkan dosis serap pada sel tumor adalah (6,17±0,37) mGy, (10,73±0,45) mGy, (10,87±0,45) mGy, dan (10,89±0,45) mGy. Besar dosis hambur di luar sel tumor telah diukur, nilai terbesar adalah pada organ otak dengan besar dosis (25,60±1,96) mGy, (122,29±1,41) mGy, (398,20±7,75) mGy, dan (597,65±6,18) mGy. Evaluasi pada dosis hambur pada organ adalah kategori aman. Lama waktu total penyinaran yang dibutuhkan (40,5±2,4) menit, (23,4±1,0) menit, (23,0±1,0) menit, dan (22,9±0,9) menit.
Analisis Distribusi Dosis pada Terapi Proton untuk Karsinoma Nasofaring Menggunakan Perangkat Lunak MCNP6 Khoirunnisa, Asma Fadhila; Suharyana, Suharyana; Riyatun, Riyatun
Prosiding SNFA (Seminar Nasional Fisika dan Aplikasinya) 2021: Prosiding SNFA (Seminar Nasional Fisika dan Aplikasinya) 2021
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/prosidingsnfa.v5i0.71817

Abstract

Abstract:. Proton characteristics in simulation of proton therapy in nasopharyngeal carcinoma were performed using MCNP6 software simulation. The nasopharyngeal carcinoma cell was modelled as a sphere with a diameter 1,56 cm. The proton beam energy used was 103 – 109 MeV fired at the carcinoma cell from two different directions, right and left. From the simulation result, the equivalent dose of cancer cells was (0,247 ± 0,002) Sv with a dose distribution in the facial skeleton, soft tissue, skin, skull, spine, and brain. The results were still within the safe limits of Organ At Risk (OAR). With the current used of 10 nA, the total duration of three treatment time for therapy was (8,10 ± 0,01) minutes.Abstrak: Karakteristik proton untuk simulasi terapi proton pada karsinoma nasofaring dilakukan dengan simulasi perangkat lunak MCNP6. Sel karsinoma nasofaring dimodelkan berbentuk bola dengan diameter 1,56 cm. Energi berkas proton yang digunakan adalah 103 – 109 MeV ditembakkan pada sel kanker dari dua arah yang berberda, yaitu kanan dan kiri. Dari hasil simulasi diperoleh dosis ekuivalen pada sel kanker sebesar (0,247 ± 0,002) Sv dengan distribusi dosis pada sel sehat yaitu kerangka wajah, jaringan lunak, kulit, tengkorak, tulang belakang dan otak yang hasilnya masih dalam batas aman Organ At Risk (OAR). Dengan arus yang digunakan sebesar 10 nA diperoleh lama waktu tiga kali penyinaran untuk terapi adalah sebesar (8,10 ± 0,01) menit.
Inisiasi Implementasi Zenius sebagai Aplikasi Pembelajaran Online di SD Muhammadiyah Wonorejo Anwar, Fuad; Soeparmi, Soeparmi; Cari, Cari; Riyatun, Riyatun; Suharyana, Suharyana; Yunianto, Mohtar; Darmanto, Darmanto
SEMAR (Jurnal Ilmu Pengetahuan, Teknologi, dan Seni bagi Masyarakat) Vol 10, No 2 (2021): November
Publisher : LPPM UNS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/semar.v10i2.52163

Abstract

Telah dilakukan inisiasi implementasi zenius yang merupakan aplikasi pembelajaran online di SD Muhammadiyah Wonorejo yang  diikuti 17 Guru. Dalam kegiatan tersebut dibagi menjadi 2 tahap, tahap pengenalan Aplikasi berbasis Desktop untuk menu pengunjung, Guru, Murid dan Orang tua. Untuk menu Guru dilatih untuk mengelola kelas, mengunggah materi pembelajaran, membuat soal, melakukan penilaian siswa serta melakukan pelaporan nilai ke orang tua. Tahap berikutnya adalah pengenalan Aplikasi berbasis Android, di latihkan untuk menu Murid, berisi lihat materi pembelajaran, presensi, mengerjakan soal ujian dan mengetahui hasil ujian. Sebelum dilakukan pelatihan sebagian besar tidak memahami aplikasi pembelajaran online, setelah dilakukan pelatihan semua peserta memahami dan akan mengimplementasikan dalam proses pembelajaran di kelas. 
Diseminasi Riset Kecerdasan Buatan Untuk Diagnosis Medis Berbasis Elektrokardiogram di Universitas Duta Bangsa Nuryani, Nuryani; Purnama, Budi; Legowo, Budi; Utari, Utari; Riyatun, Riyatun; Suharno, Suharno; Yunianto, Mohtar; Lestari, Wiji
SEMAR (Jurnal Ilmu Pengetahuan, Teknologi, dan Seni bagi Masyarakat) Vol 12, No 2 (2023): November
Publisher : LPPM UNS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/semar.v12i2.75521

Abstract

Kegiatan pengabdian masyarakat ini memaparkan diseminasi riset yang bertujuan untuk memperkenalkan konsep kecerdasan buatan (artificial intelligence/AI) dalam diagnosis medis berbasis elektrokardiogram (EKG) kepada para dosen di Fakultas Ilmu Komputer, Universitas Duta Bangsa. Kegiatan ini bertujuan untuk meningkatkan pemahaman para dosen tentang potensi aplikasi AI dalam bidang kesehatan dan memberikan wawasan baru mengenai penggunaan EKG dalam diagnosis gangguan kesehatan. Para dosen diajak untuk mempelajari aplikasi AI dan teknik-teknik yang digunakan dalam analisis EKG. Hasil dari kegiatan ini menunjukkan bahwa para dosen memiliki minat yang tinggi dalam menerapkan kecerdasan buatan dalam bidang medis, khususnya dalam diagnosis penyakit jantung melalui EKG. Mereka memahami potensi besar yang dimiliki oleh AI dalam meningkatkan akurasi dan kecepatan diagnosis, serta membantu dalam pengambilan keputusan klinis yang lebih baik.