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All Journal Jurnal Biologi Tropis JURNAL FARMASIMED (JFM) Jurnal Farmasi Sains dan Praktis Jurnal Kebidanan, Keperawatan dan Kesehatan (J-BIKES)
Khairani, Tetty Noverita
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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MORINGA LEAF (Moringa Oleifera L.) ETHANOL EXTRACT CLAY MASK FORMULATION AS ANTI-AGING Nurussakinah, Nurussakinah; Fhitriana, Suzan; Khairani, Tetty Noverita; Utari, Sri
Jurnal FARMASIMED (JFM) Vol 6 No 1 (2023): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jfm.v6i1.1193

Abstract

Aging is a human physical change caused by age, psychological, and social factors, especially on the face, neck, upper arms and hands. Aging is unavoidable and goes at different speeds, depending on one's genetics, environment and lifestyle. Synthetic antiocxidant products are many circulated in the market which have a negative impact on health. However Antioxidant compound are widely spread in nature expecially in plant. Moringa leaf is one of plants that contain abundant antioxidant, alkaloids, flavonoids, phenolics, triterpenoids/steroids and tannins. Many of people Switch to natural products. Mask from natural products are not causing irritation or less side effects. clay face mask are mostly used because of their skin rejuvenating abilities. Purpose: To know either Moringa leaf ethanol extract can be formulated in clay mask preparations and the optimal effect is to prevent aging or not. Methods: the research is including how to make clay mask with ethanol extract of Moringa leaves at concentrations of 6%, 8% and 10%. The evaluation of the physical quality of the preparation, testing the effectiveness of clay masks with ethanol extract of Moringa leaves as anti-aging. Result: the preparation is qualify the characteristic test, had a pH of 4.9-5.2, a drying time of 15-23.5 minutes, an o/w emulsion type, was stable for 12 weeks of storage, and was not caused irritation. The best result of anti-aging effectiveness test was at a concentration of 10% with 36.25 moisture content, 23.25 fineness content, 33.75 pores, 20.5 blemishes and 15.5 wrinkles. Conclusion: Moringa leaf ethanol extract can be formulated in clay mask , and is able to give the best anti-aging effect at 10% formula.
ANTIBACTERIAL ACTIVITY OF BASIL LEAVES EXTRACT TOWARDS BACTERIA STAPHYLOCOCCUS AUREUS AND STAPHYLOCOCCUS EPIDERMIDIS IN DEODORANT SPRAY Khairani, Tetty Noverita; Fitri, Khairani; Andry, Muhammad; Nasution, Muhammad Amin
Jurnal Farmasi Sains dan Praktis Vol 9 No 3 (September-December 2023)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/pharmacy.v9i3.7542

Abstract

Body odor is a significant problem and is often encountered in some individuals characterized by excessive odor. A deodorant spray made from basil leaf (Ocimum Basilicum L.) extract is a product used to treat body odor caused by Staphylococcus Aureus and Staphylococcus epidermidis bacteria. The purpose of this study is to assess the efficacy of deodorant spray and basil leaf extract on bacterial activity, as well as the optimal dose of deodorant spray for lowering the activity of these bacteria. Method the research was conducted experimentally, testing antibacterial activity using agar diffusion. The results of the deodorant spray preparation test showed that the preparation was homogeneous, organoleptically brown in color, had a distinctive smell, and had a liquid texture; the pH test results met the requirements for deodorant spray 4.5-6.5. The average diameter of the inhibition zones produced from each preparation were Staphylococcus epidermidis bacteria, positive control 7 mm, negative control 10.1 mm; formula 5% 12.3 mm; formula 10% 13.3 mm; formula 15% 12.7 mm maximum concentration in inhibiting bacteria is formula 10% by 13.3 mm, while the bacteria Staphylococcus Aureus positive control 13 mm, negative control 11.2 mm, 5% formula 13.1 mm; formula 10% 13.4 mm; 15% formula 13.9 mm maximum concentration in inhibiting bacteria is 15% formula 13.9 mm. Based on the inhibitory zone created by 10% basil leaf ethanol extract, Staphylococcus epidermidis bacteria had a 13.3 mm clean zone and Staphylococcus aureus bacteria had a 26.5 mm clean zone.
Uji Aktivitas Antijamur Ekstrak Etanol Umbi Bawang Batak (Allium Chinense G.Don) Terhadap Candida Albicans Dan Malasssezia Furfur Handayani, Sri; Nasution, Rizka Hasmi; Khairani, Tetty Noverita; Fadhillah, Annisa Nur
JURNAL KEBIDANAN, KEPERAWATAN DAN KESEHATAN (BIKES) Vol 4, No 2 (2024): J-BIKES NOVEMBER
Publisher : Mata Pena Madani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51849/j-bikes.v4i2.98

Abstract

Jamur adalah suatu organisme heterotrop artinya untuk hidupnya memerlukan zat-zat organik dari organisme lainnya. Jamur dapat menyebabkan penyakit akut dan subakut di mulut, vagina, kulit, kuku, paru-paru dan pencernaan. Penyakit ini dapat mempengaruhi semua kelompok umur baik laki-laki maupun perempuan. Obat tradisional digunakan sebagai pengobatan alternatif karena berasal dari tanaman, termasuk bawang batak (Allium chinense G.Don) yang memiliki sifat antijamur. Penelitian ini bertujuan untuk mengetahui efektivitas antijamur ekstrak etanol umbi bawang batak terhadap jamur Candida albicans dan Malasssezia furfur. Metode penelitian ini dilakukan secara eksperimental, untuk menguji ekstrak umbi bawang batak (Allium chinense G.Don) dengan beberapa variasi konsentrasi terhadap pertumbuhan jamur Candida albicans dan Malassezia furfur serta zona hambatnya. Hasil ekstrak dan simplisia umbi bawang batak mengandung senyawa kimia, flavonoid, alkaloid, saponin dan triterpenoid. Ekstrak umbi bawang batak memiliki aktivitas antijamur terhadap jamur Candida albicans dan Malasssezia furfur dengan nilai rata-rata Candida albicans (10%) sebesar 8,6 mm, (20%) sebesar 9,2 mm, (30%) sebesar 10,9 mm dan Malasssezia furfur (10%) sebesar 8,3 mm, (20%) sebesar 10,1 mm, (30%) sebesar 11,9 mm.
Antifungal Activity Test of Jamaican Cherry Leaf (Muntingia calabura l.) Ethanol Extract in Inhibiting Growth of Fungi Malassezia furfur and Pityrosporum ovale Khairani, Tetty Noverita; Neswita, Elfia; Nurasni, Nurasni; Fitri, Khairani; Amanda, Asri
Jurnal Biologi Tropis Vol. 25 No. 3 (2025): Juli-September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i3.9510

Abstract

The plant species known as Jamaican Cherry Leaf (Muntingia calabura L.) belongs to the Muntingiaceae family. Flavonoid compounds, tannins, saponins, and steroids are all found in Jamaican cherry leaves. One of them has antifungals that can stop Pityrosporum ovale and Malassezia furfur from growing, and it is utilized as a traditional medication. This study aimed to determine the antifungal activity and the most effective concentration of Jamaican cherry leaves in inhibiting the growth of Malassezia furfur and Pityrosporum ovale fungi. Methods research is an experimental research. The research phase includes sampling, making simplicia, extract making, testing the characteristics of simplicia and extract, testing the inhibitory power of ethanol extract of Jamaican cherry leaf against fungi (Malassezia furfur and Pityrosporum ovale) by comparing the 2% ketoconazole antibiotic. The results showed the inhibition of ethanol extract of Jamaican cherry leaf (Muntingia calabura L.) against the growth of Malassezia furfur at F1 (7.2 mm), F2 (9.8 mm), F3 (11 mm) with and F4 (6.8 mm). mm) while against the growth of the fungus Pityrosporum ovale at F1 (7.0 mm), F2 (9.11 mm), F3 (10.2 mm) and F4 (6.3 mm). The best inhibition zone was formed at 30% concentration treatment with strong category. The conclusion shows that the ethanol extract of Jamaican cherry leaf (Muntingia calabura L.) can inhibit the growth of Malassezia furfur and Pityrosporum ovale fungi.
Anti-Fungal Activity Testing of Purple Cabbage (Brassica oleracea Linn.) Ethanol Extract in Inhibiting The Fungi Growth Candida albicans and Malassezia furfur Khairani, Tetty Noverita; Fitri, Khairani; Andry, Muhammad; Sarumaha, Paska Eli
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.8009

Abstract

One of the plants that has the potential to be utilized as medicine is purple cabbage (Brassica oleracea Linn.). Commensal fungi like Candida albicans and Malassezia furfur can be found in the genitourinary tract, vagina, urethra, skin, fingers, and toes, among other places on the body. The purpose of: The study aimed to learn more about the antifungal properties of the ethanol extract of purple cabbage in preventing the growth of Malassezia furfur and Candida albicans. This study used an experimental design to examine the independent variables of the purple cabbage extract with various doses of the growth activity test of Candida albicans and Malassezia furfur, as well as their inhibition zones. Purple cabbage contains steroids, saponins, tannins, and flavonoid compounds. With concentrations of 10%, 20%, 30%, and positive control, the average diameter of the inhibitory zone for Candida albicans was 4.83 mm, 7.2mm, 8.75mm, and 6.21mm. The concentrations of Malassezia furfur at 10%, 20%, 30%, and the positive control were 4.61mm, 6.36mm, 8.83mm, and 6.15mm, respectively. As a negative control, DMSO failed to exhibit an inhibitory zone. Statistics revealed a substantial difference, indicating that the concentration had an impact on how the inhibition zone developed. The ethanol extract of purple cabbage has antifungal action, and the treatment with the 30% extract concentration forms the optimal concentration. It is advised that more research be done on the antifungal activity of purple cabbage extract against various kinds of fungus and that dosage forms be created for it.
Co-Authors Amanda, Asri Fadhillah, Annisa Nur Fhitriana, Suzan Fitri, Khairani Handayani, Sri Khairani Fitri Muhammad Amin Nasution Muhammad Andry Muhammad Andry Nasution, Rizka Hasmi Neswita, Elfia nurasni, nurasni Nurussakinah, Nurussakinah Sarumaha, Paska Eli Utari, Sri