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All Journal Journal of Islamic Pharmacy Jurnal Biologi Tropis JURNAL PENDIDIKAN TAMBUSAI JOURNAL LA MEDIHEALTICO
Ginting, Indra
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Formulasi Sediaan Lulur Krim Dari Ekstrak Etanol Daun Pepaya (Carica papaya L.) Sebagai Pelembab Kulit Leny, Leny; Rudang, Singgar Ni; Ginting, Indra; Simanjuntak, Heppy Taruli
Journal of Islamic Pharmacy Vol 8, No 1 (2023): J. Islamic Pharm.
Publisher : Universitas Islam Negeri Maulana Malik Ibrahim Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18860/jip.v8i1.20793

Abstract

Pengelupasan kulit diperlukan dalam membuang atau mengangkat sel-sel permukaan kulit yang mati dan kering serta dapat membuat tekstur kulit menjadi merata dan halus. Eksfolian fisik seperti scrub bekerja untuk mengelupaskan kulit mati secara instan. Kebanyakan orang mungkin tidak cocok melakukan eksfoliasi setiap hari, karena dapat menyebabkan kulit menjadi kering dan mudah teriritasi. Untuk itu, senyawa alami yang digunakan dalam pembuatan lulur dapat menjadi pilihan yang lebih baik dalam mengangkat sel mati sekaligus menutrisi kulit dengan banyak senyawa antioksidan. Daun pepaya mengandung senyawa kimia yang bersifat antiseptik, antiradang, antijamur, dan antibakteri. Senyawa antibakteri yang terdapat pada daun pepaya antara lain tanin, flavonoid, alkaloid, terpenoid, dan saponin. Selain itu, daun pepaya mengandung vitamin C dan E (masing-masing 68,59 dan 39,78mg/100 g). Tujuan dari penelitian ini adalah memformulasi sediaan krim lulur ekstrak etanol 70% dari daun pepaya yang memiliki kemampuan dalam meningkatkan kelembaban. Penelitian dilakukan secara eksperimental, meliputi pembuatan simplisia, ekstrak, sediaan lulur krim dan pemeriksaan sediaan secara fisik maupun efektivitasnya terhadap kulit sukarelawan. Studi menunjukkan bahwa tidak ada perubahan bentuk, warna dan bau setelah 12 minggu penyimpanan; uji homogenitas menunjukkan preparat homogen; sediaan menunjukkan kisaran pH 6,5-6,9; jenis emulsi adalah fase minyak dalam air sehingga krim mudah diaplikasikan, menyebar dan didispersikan dengan air; tes iritasi menunjukkan tidak ada kemerahan, gatal dan panas pada kulit sukarelawan. Dapat disimpulkan bahwa ekstrak etanol 70% dari daun pepaya (Carica papaya L.) dapat diformulasikan sebagai krim lulur dan dengan konsentrasi 15% ekstrak daun pepaya memberikan efek terbaik dalam meningkatkan kelembaban kulit. 
Analysis of Drug Availability Management at the Regional General Hospital Pharmacy Installation Sani, Hapiz Arlanda; Asriwati, Asriwati; Nyorong, Mappeaty; Sari, Mayang; Ginting, Indra
Journal La Medihealtico Vol. 4 No. 2 (2023): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v4i2.837

Abstract

Pharmacy managerial activities are inseparable from the principles of drug availability management such as a series of needs planning activities, procurement, storage and distribution of drugs through hospital pharmacy installations. This study aims to analyze and obtain information on availability management at the Pharmacy Installation of the South Tapanuli Regional General Hospital. This type of research is qualitative with a descriptive approach using primary data and secondary data using the interview method. The informants interviewed at the pharmaceutical installation were the head of the pharmaceutical installation unit, the coordinator of pharmacy services, the head of the pharmaceutical warehouse/supplies, the coordinator of quality management and administration. Informants of this study were taken by purposive sampling and data analysis using triangulation and data reduction methods. The results of this study obtained that planning for drug needs uses the consumption method by looking at the need for previous use, but it has not been maximized, procurement has not gone well, drug shortages often occur, drug storage systems use the FIFO (First in First Out) and FEFO (First Expired First Out) systems. First Expired First Out). Storage is not up to standard, the waiting time for drug distribution to patients starting from the patient submitting the prescription to the delivery of the drug takes quite a long time for the drug to be finished. The conclusion is that the implementation of drug availability management has not run optimally according to standard operating procedures for services, so it is necessary to increase human resource knowledge through training related to drug planning.
Comparison of Effectiveness and Duration of Recovery in Acne Treatment Using a Topical Approach Systemics and Lasers Ginting, Indra; Mukhali, Hassan Basri Bin; Abas, Mohd Ihsanuddin Bin; Aji, Andrey; Rachelli, Rachelli; Dakhi, Tiwanto; Rudang, Singgar Ni
Jurnal Pendidikan Tambusai Vol. 9 No. 1 (2025)
Publisher : LPPM Universitas Pahlawan Tuanku Tambusai, Riau, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Jerawat adalah kondisi kulit kronis yang dapat memengaruhi kualitas hidup penderitanya. Penelitian ini bertujuan untuk membandingkan kemanjuran dan durasi pemulihan dari tiga metode pengobatan jerawat utama: topikal, sistemik, dan laser. Pendekatan retrospektif dilakukan dengan menganalisis data pasien yang menjalani perawatan di klinik dermatologi, menggunakan IGA (Investigator's Global Assessment) untuk menilai keparahan jerawat dan skor CADI (Cardiff Acne Disability Index) untuk mengevaluasi dampak terhadap kualitas hidup. Hasil penelitian menunjukkan bahwa terapi laser memiliki efektivitas tertinggi dengan penurunan skor CADI sebesar 90% dalam waktu 4 minggu dan durasi pemulihan rata-rata 8 minggu, lebih cepat dibandingkan terapi sistemik (10 minggu) dan topikal (12 minggu). Kepuasan pasien tertinggi tercatat pada kelompok terapi laser dengan skor 4,7, diikuti terapi sistemik dan topikal masing-masing 4,2 dan 3,8. Meskipun terapi laser lebih mahal, terapi sistemik tetap efektif untuk jerawat sedang hingga berat, dan terapi topikal lebih cocok untuk jerawat ringan meski membutuhkan waktu pemulihan lebih lama. Penelitian ini menyarankan agar pemilihan terapi didasarkan pada tingkat keparahan jerawat, durasi pemulihan, dan preferensi pasien, memberikan panduan bagi praktisi dermatologi dalam merancang pengobatan yang optimal.
Formulation of Natural Food Coloring Granules from Dragon Fruit Peel Extract (Hylocereus polyrhizus) and Effectiveness Test in Reducing Blood Glucose Levels Rudang, Singgar Ni; Ginting, Indra; Andry, Muhammad
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7635

Abstract

Anthocyanin is one of the many compounds in dragon fruit skin that can be used as an antioxidant. Dragon fruit skin can also lower blood glucose levels. The fact that cases of diabetes mellitus are increasing every year shows that this disease needs serious treatment. This study aims to make dragon fruit skin extract formulated in the form of granules and make dragon fruit skin extract granules that meet the requirements as natural food coloring and to determine the content and effectiveness of dragon fruit skin extract (Hylocereus polyrhizus) which can lower blood glucose levels. This research method is experimental. The One Way Anova test and the Tukey HSD post-hoc test were used to analyze the data. The outcomes showed that there were 9 granule recipes that met the assessment test necessities. After being induced by 20% fructose solution, the glucose level study revealed that the treatment of dragon fruit skin extract at 100, 200, and 400 mg / kgBW was able to lower blood glucose levels in test animals. Winged serpent natural product skin concentrate can be formed as granules. Equations 2 and 3 produce the best tone. The consequences of the review reasoned that winged serpent natural product skin remove (Hylocereus polyrhizus) at dosages of 100, 200 and 400 mg/kgBW was viable in decreasing blood glucose levels in guinea pigs prompted by 20% fructose arrangement and a portion of 200 mg/kgBW gave an impact of lessening blood glucose levels that was practically equivalent to the positive control.
Formulation and Evaluation of Facial Wash Gel Preparation from Celery Leaf Ethanol Extract (Apium graveolens L.) Against Staphylococcus aureus Bacteria Ginting, Indra; Mukhali, Hassan Basri bin; Abas, Mohd Ihsanuddin Bin; Aji, Andrey; Rachelli, Rachelli; Andry, Muhammad; Sibero, Jitasari Tarigan; Rudang, Singgar Ni
Jurnal Biologi Tropis Vol. 25 No. 1 (2025): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i1.8500

Abstract

Facial wash is a facial cleansing soap that can clean oil and cosmetics that stick to the face. Usually facial wash has a low pH or close to the skin's normal pH, namely 4.5-6.5 and contains milder detergent. Researchers are to determine which celery leaf extract (Apium graveolens L.) is being evaluated as a facial wash preparation and to determine which facial wash preparation has inhibitory power for the growth of Staphylococcus aureus bacteria. This research is experimental using the maceration method. The sample used in this research was 10 kilograms of celery leaves. Results : Testing the pH of the celery leaf ethanol extract facial wash gel preparation for each F0, F1, F2 and F3 showed that the pH of the celery leaf ethanol extract facial wash gel preparation decreased due to the presence of acid compounds in celery leaves, causing the pH to decrease slightly but still within the pH range. topical, namely 4.5-7.0 and the pH of the celery leaf ethanol extract facial wash gel preparation above shows a relatively neutral pH which is still safe for the skin. The facial wash gel preparation of ethanol extract of celery leaves (Apium graveolens L.) has an inhibitory zone containing Staphylococcus aureus bacteria in K(+), K(-), F1 (5%), F2 (10%) and F3 (15%) with strong inhibition zone category. Researchers found that the ethanol extract of celery leaves can be formulated in the form of a facial wash gel. It is recommended that further research be carried out on the effectiveness of celery leaves with different concentrations and methods.
Formulation and Evaluation of a Sheet Mask with Ethanol Extract of Mengkudu (Morinda citrifolia L.) as a Moisturizing Agent Ginting, Indra; Mukhali, Hassan Basri bin; Abas, Mohd Ihsanuddin Bin; Aji, Andrey; Rachelli, Rachelli; Rudang, Singgar Ni
Jurnal Biologi Tropis Vol. 25 No. 1 (2025): Januari - Maret
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i1.8551

Abstract

Facial skin often faces issues such as acne, dullness, and dryness. Sheet masks are one of the cosmetic care products that can help maintain facial skin hydration. Noni leaves (Morinda citrifolia L.) contain secondary metabolite compounds such as alkaloids, tannins, saponins, and flavonoids, which can act as antioxidants.  To determine whether noni leaf ethanol extract can be formulated into a sheet mask preparation and its effectiveness as a moisturiser. The research involved several steps: plant identification/determination, sample collection, extraction using the maceration method with 70% ethanol solvent, formulation of the sheet mask preparation, and evaluation, including organoleptic tests, homogeneity, pH, stability, irritation, and moisture effectiveness testing using a skin analyser. Sheet mask preparations with 5%, 7%, and 10% concentrations were found to be thick, homogeneous, with pH ranging from 4.42 to 5.72, non-irritating, stable during storage, and increased skin moisture by 78.94% for F1, 84.0% for F2, and 85.15% for F3. Noni leaf ethanol extract can be formulated into sheet mask preparations and is effective in moisturising the skin. Keywords: Noni leaf extract, sheet mask, moisture.
Co-Authors Abas, Mohd Ihsanuddin Bin Aji, Andrey Asriwati, Asriwati Dakhi, Tiwanto Leny Leny, Leny Mappeaty Nyorong Mayang Sari Muhammad Andry Mukhali, Hassan Basri bin Rachelli, Rachelli Rudang, Singgar Ni Sani, Hapiz Arlanda Sibero, Jitasari Tarigan Simanjuntak, Heppy Taruli