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ANALYSIS OF APO-B SERUM LEVELS IN BALB/C MICE HYPERCHOLESTEROLEMIC AGAINST TEMULAWAK EXTRACT (Curcuma xanthoriza Roxb) Riyadatus Solihah; M. Shofwan Haris; Yogi Khoirul Abror
JURNAL INDONESIA DARI ILMU LABORATORIUM MEDIS DAN TEKNOLOGI Vol 1 No 1 (2019): The Value, Importance, and Oversight of Health Research
Publisher : Universitas Nahdlatul Ulama Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/ijmlst.v1i1.799

Abstract

APO–B Serum levels is the most predictive value for the incidence of atherosclerosis and coronary heart disease. Curcuma xanthorrhiza Roxb contains curcumin, which can be used as an antioxidant, anti–inflammatory and antihypercholesterol. The mechanism of curcumin contained in ginger to reduce cholesterol is due to its function as a cholagoga or bile stimulant. This study aims to determine the effect of temulawak extract on the levels of APO–B Serum in hypercholesterolemia mice. This research were a true experimental study with a post–test only control group design carried out in February 2018. The extraction As much as 25 mice were divided into 5 groups where are group consisted of 5 mice. Positive control group (K+) were treated with high cholesterol feed and water, negative control group (K–) were given standard feed and water, treatment group 1 (P1) were given high cholesterol food and 25mg/kg BW of curcuma extract for 14 days, treatment group 2 (P2) were treated with foods high in cholesterol and 50mg/kg BW of curcuma extract for 14 days and treatment group 3 (P3) treated with high cholesterol and ginger extract 75mg/kg BW for 14 days. Examination of APO–B levels were measured using the spectrophotometric method. Data were analyzed using One–Way Anova. The results showed that the average of APO–B level at (K+) was 209.7 ± 1.02 mg / dL, at (K–) 115.3 ± 1.04 mg / dL, at (P1) 180.4 ± 1.07 mg / dL, at (P2) 147.6 ± 1.12 mg / dL, at (P3) 119.1 ± 1.10 mg / dL. Based on the results of statistical test it was found that there was a significant decrease in APO–B levels with p–value= 0.001 at alpha 0.05 (p <α).
Tahu Sabar (Sari Bahari) Upaya Pemanfaatan Limbah Produksi Garam sebagai Tahu Bahan Organik Ramah Lingkungan bagi Penderita Stunting Rahmad Wahyudi; Harfina Indriani; M.Shofwan Haris
Amerta Nutrition Vol. 6 No. 1 (2022): AMERTA NUTRITION
Publisher : Universitas Airlangga, Kampus C, Mulyorejo, Surabaya-60115, East Java, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v6i1.2022.44-52

Abstract

Latar Belakang: Stunting menjadi masalah kritis optimalisasi pertumbuhan dan perkembangan balita. Kurangnya asupan makanan yang mengandung zat gizi menjadi salah satu faktor penentu penyebab kejadian stunting. Tahu salah satu makanan yang menjadi solusi untuk pencegahan stunting. Produksi tahu sebagian besar masih menggunakan koagulan cuka yang tidak ramah lingkungan memberikan dampak buruk terhadap lingkungan dan kesehatan.Tujuan: Penelitian ini memanfaatan limbah produksi garam di wilayah madura sebagai tahu bahan organik ramah lingkungan bagi penderita stunting.Metode: Penelitian ini dilaksanakan di Laboratorium Stikes Ngudia Husada Madura Bangkalan dan PT. Angler Biochemlab Surabaya dengan mengambil sampel limbah produksi garam (sari bahari) yang berada di wilayah madura. Dilakukan pembuatan tahu dengan bahan dasar kedelai dengan koagulan berbeda. Tahu A dengan koagulan cuka sedangkan Tahu B dengan koagulan nigari atau sari bahari. Dilakukan proses pemanasan dan dilakukan proses pengepresan dan pencetakan tahu kemudian dilakukan uji analisis kandungan, uji pH sisa limbah perasan tahu, masa dan tekstur tahu.Hasil: penelitian menunjukan volume limbah sisa air perasan tahu cuka 225 ml lebih banyak dari pada tahu sari bahari 25 ml, pH tahu cuka cenderung asam dengan nilai 4,8 sedangkan tahu sari bahari cenderung basa dengan nilai 6,7. Uji kandungan tahu sari bahari dengan indikator protein (18,3 g), lemak (3,99 g) dan kadar air (73 g) lebih tinggi dari tahu cuka dengan nilai protein (17,4 g), lemak (10,9), kadar air (67,3 g).Kesimpulan: Makanan dengan kandungan protein tinggi diperlukan tubuh untuk membangun matriks tulang dan mempengaruhi pertumbuhan tulang.
ANALISIS KADAR APO-A1 SERUM PADA TIKUS PUTIH STRAIN WISTAR (Rattus novergicus) DISLIPIDEMIA TERHADAP PEMBERIAN EKSTRAK KULIT BUAH APEL [Malus sylvestris Mill] VARIETAS ROOM BEAUTY Riyadatus Sholihah; M. shofwan Haris
JURNAL MEDICAL P-ISSN : 2685-7960 e-ISSN : 2685-7979 Vol 1 No 1 (2019): MARET
Publisher : NHM PRESS

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Abstract

Dislipidemia adalah gangguan metabolisme lipid yang ditandai dengan peningkatan kadar kolesterol total, trigliserida, low density lipoprotein atau penurunan high-density lipoprotein dalam darah, sedangkan hiperlipidemia adalah kondisi dimana terjadi peningkatan kadar lipid yaitu trigliserida darah, kolersterol. atau keduanya. Keadaan ini tehadap resiko tinggi penyakit kardiovaskuler (CVD). Jika data normal dan homogen, maka dilanjutkan dengan uji annova satu jalan dengan tingkat signifikansi uji, pada varians p = 0,05. Uji varians diperoleh tingkat signifikan dengan Apo A1 diperoleh p = 0,001, data memiliki p <0,05 yang berarti ada pengaruh yang signifikan ekstrak Kulit Apo terhadap peningkatan kadar dan Apo A1 pada tikus. Ekstrak kulit apel mengandung pektin yang mengaktifkan d PPAR α dapat meningkatkan kadar Apo-A1 serum dalam sirkulasi yang merupakan fraksi protein utama dan terbesar yang berperan dalam transpor kolesterol.
Pengaruh Apoteker Pengelola Apotek (APA) Terhadap Kualitas Pelayanan Kefarmasian Di Apotek Kabupaten Bangkalan M. Shofwan Haris
DIA: Jurnal Administrasi Publik Vol 12 No 01 (2014): IMPLEMENTASI KEBIJAKAN
Publisher : Program Studi Doktor Ilmu Administrasi, FISIP, Universitas 17 Agustus 1945 Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (319.65 KB) | DOI: 10.30996/dia.v12i01.945

Abstract

Nowadays, the paradigm of pharmacy services has began into patient orientation and known as Pharmaceutical Care. The role of pharmacist is giving a consultation, information, and education related with medical therapy to patient, directing patient to do healthy lifestyle therefore it will supporting the medical process. Besides, it could monitor the medical theraphy’s result by the patient and also collaborate with other healthy proffesional to improve quality life of the patient. The objective of this research is to explore APA’s factor that affects the quality pharmacy services of pharmacies which has not been done at Bangkalan District by the pharmacist that the manager of the pharmacy (APA) and to determine the variables of APA’s factor the most influence on quality pharmacy services of pharmacies. This research used an observational framework of cross-sectional analytic and sample collecting methode by Simple Random Sampling towards 52 pharmacies at Bangkalan District. Type of data has been used was primary data based on give questioner and observation towards APA at Bangkalan District. The results using multiple linear regression. The results showed that the partial all of  APA’s factor that tangible, reliability, responsiveness, assurance, and emphaty had a significant impact on quality pharmacy service of pharmacies with level of significance under of α = 0,05. While simultaneously the APA’s factor significant influence on quality pharmacy service of pharmacies at Bangkalan District.Keywords: the Manager of the Pharmacy (APA), quality pharmacy service of pharmacies
Konseling Dagusibu Obat sebagai Upaya Peningkatan Pemahaman pada Remaja di SMPN Satap Bujur Barat Pamekasan April Nuraini; Riyadatus Solihah; M Shofwan Haris; Ratri Rokhani; Metta Kristina; Rizal Umar Rahmadani; Dianita Rahayu Puspitasari
Bubungan Tinggi: Jurnal Pengabdian Masyarakat Vol 5, No 1 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/btjpm.v5i1.7478

Abstract

Fasilitas dan informasi kesehatan yang minimal menyebabkan rendahnya pemahaman masyarakat mengenai informasi pengelolaan obat dan swamedikasi. Informasi pengelolaan obat yaitu dapatkan, gunakan, simpan, buang obat yang dikenal sebagai DAGUSIBU. Tujuan konseling ini yaitu mengenalkan DAGUSIBU obat di kalangan remaja. Peserta dari kegiatan ini sebanyak 34 siswa Sekolah Menengah Pertama Negeri (SMPN) Satap Bujur Barat Pamekasan yang dilaksanakan pada tanggal 10 Desember 2022. Peserta secara langsung mendapatkan leaflet yang berisi materi DAGUSIBU. Penjelasan materi dengan metode ceramah melalui media powerpoint yang didukung dengan perlengkapan peraga obat-obatan sebagai contoh penerapan DAGUSIBU. Pelaksanaan kegiatan ini meliputi pretest, konseling tentang DAGUSIBU obat, diskusi, tanya jawab dan ditutup dengan posttest. Dari hasil evaluasi konseling mengenai DAGUSIBU obat menunjukkan respon yang sangat baik, ditandai dengan atensi peserta melalui diskusi dan tanya jawab. Hasil dari kegiatan ini menunjukkan bahwa adanya peningkatan rata-rata skor pretest dan posttest yaitu sebesar 107%. Kesimpulan dari kegiatan ini menunjukkan bahwa adanya peningkatan pemahaman mengenai pengelolaan obat DAGUSIBU setelah diberikan konseling.Minimal health facilities and Information cause low public understanding of drug management information and self-medication. Drug management information, i.e. gets, uses, stores, and disposes of drugs, is known as DAGUSIBU. The purpose of this counselling is to introduce DAGUSIBU drugs among adolescents. The participants of this activity were 34 students of Satap Bujur Pamekasan Junior High School (SMPN), which was held on December 10, 2022. Participants directly received a leaflet containing DAGUSIBU material. Explanation of the material by the method of lectures through the media PowerPoint supported with props drugs as an example of the application of DAGUSIBU. The implementation of this activity includes a pretest, counselling about DAGUSIBU drugs, discussion, question and answer and closed with a posttest. The evaluation of socialization about DAGUSIBU drugs showed a very good response, marked by participants' attention through discussion and question and answer. This activity's results showed an increase in the average pretest and posttest scores of 107%. This activity's conclusion shows an increased understanding of DAGUSIBU drug management after counselling. 
RED BETEL LEAF EXTRACT SERUM (Piper ornatum) AS AN ALTERNATIVE ANTI-HEAD LICE TREATMENT Rizal Umar Z; Riyadatus Solihah; M Shofwan Haris
NURSING UPDATE : Jurnal Ilmiah Ilmu Keperawatan P-ISSN : 2085-5931 e-ISSN : 2623-2871 Vol 13 No 3 (2022): SEPTEMBER
Publisher : NHM PRESS

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Abstract

Lice (Pediculus humanus capitis) or known as head lice are ectoparasites that live on the human scalp, the main symptom felt is itching on the scalp caused by lice bites on the scalp. Lice are often found in children aged 7-10 years and also in adults, lice can live on the scalp, body and hair of the pubic area, and can cause itching, scabs, loss of concentration, lack of sleep, and lack of confidence. One way to overcome this is to use anti-lice shampoo. Some studies state that betel leaf extract can kill head lice. Thus, article aims to find out what serum concentration of red betel leaf extract (Piper ornatum) is effective against the death of head lice (Pediculus humanus capitis).
Profil Pengetahuan dan Persepsi Orang Tua terhadap Penggunaan Antibiotik pada Anak di Apotek Bangkalan April Nuraini; M. Shofwan Haris; Dianita Rahayu Rahayu; Ratri Rokhani
JOPS (Journal Of Pharmacy and Science) Vol 6 No 2 (2023): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v6i2.3426

Abstract

Antibiotik merupakan terapi utama pada penyakit infeksi yang disebabkan oleh bakteri. Penggunaan antibiotik pada anak seringkali menimbulkan masalah karena penyalahgunaanya.Tujuan dilakukannya penelitian ini adalah untuk mengetahui profil pengetahuan dan persepsi terhadap penggunaan antibiotik yang didasarkan pada teori Health Belief Model. Penelitian dilakukan pada orang tua pasien anak yang mendapatkan resep antibiotik di Apotek Bamara Medika Bangkalan. Penelitian ini merupakan penelitian cross sectional menggunakan alat bantu kuesioner. Analisis dilakukan secara deskriptif. Total terdapat 96 responden yang terlibat dalam penelitian ini, sebanyak 24% responden pria dan 76% responden wanita. Secara umum pengetahuan responden berada pada kategori cukup cenderung tinggi. Persentase cukup 36,5% dan tinggi 31,3%. Topik pengetahuan dengan nilai tertinggi berada pada topik aturan pakai dan pengertian antibiotik namun rendah pada topik resistensi. Persepsi responden didapatkan dari nilai 4 perceived yang diperhitungkan yaitu perceived benefit, perceived barrier, perceived threat dan perceived self-efficacy. Hasil persepsi responden menunjukkan kategori cukup dengan persentase perceived benefit 41,7%, perceived barrier 39,6%, perceived threat 66,7% dan perceived self-efficacy 40,7%.
PERBEDAAN SEDIMEN URINE Ca-OKSALAT PADA KONSUMEN AIR SUMUR DAN AIR MINERAL DI DUSUN KEMEREH DEJEH Riyadatus Solihah; Yogi Khoirul Abror; M. Shofwan Haris
JURNAL RISET KESEHATAN POLTEKKES DEPKES BANDUNG, Online ISSN 2579-8103 Vol 15 No 1 (2023): Jurnal Riset Kesehatan Poltekkes Depkes Bandung
Publisher : Poltekkes Kemenkes Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34011/juriskesbdg.v15i1.2108

Abstract

Air merupakan kebutuhan penting bagi makhluk hidup dimuka bumi, terutama bagi manusia. Mayoritas masyarakat yang hidup di desa memiliki kebiasaan mengkonsumsi air sumur. Kondisi geografis yang relatif tandus dan kering serta berada pada hamparan batuan kapur membuat kondisi air sumur mengandung butiran-butiran kapur yang dapat menimbulkan permasalahn kesehatan seperti batu ginjal akibat penumpukan sedimen pada nefron. Tujuan dari penelitian ini adalah mengetahui perbedaan hasil sedimen urine Ca-oksalat pada konsumen air sumur dan air mineral. Metode penelitian yang digunakan dalam penelitian ini adalah eksperimental dengan desain penelitian cross sectional. Teknik sampling yang digunakan purposive sampling dengan populasi 233 responden dan didapat 25 responden konsumen air sumur dan 25 responden konsumen air mineral di Dusun Kemereh Dejeh. Hasil yang didapatkan dari 25 sampel urine konsumen air sumur menunjukkan 9 sampel (36%) positif Ca oksalat, sedangkan 16 sampel (64%) negatif Ca oksalat. 25 sampel konsumen air mineral negatif Ca oksalat karena tidak ditemukan Ca oksalat. Hasil uji statistika yang dilakukan dengan dengan uji Wilcoxon didapatkan nilai signifikan 0,003 (p ≤ 0,05) sehingga dapat disimpulkan terdapat perbedaan hasil sedimen urine Ca oksalat pada konsumen air sumur dan air mineral.
OCCURRENCE OF GLAUCOMA INCIDENCE AND DIABETES MELLITUS AT KMU MADURA EYE CLINIC Riyadatus Solihah Solihah; M. Shofwan Haris; Rizal Umar
INTERNATIONAL JOURNAL OF NURSING AND MIDWIFERY SCIENCE (IJNMS) Vol 7 No 2A (2023): VOLUME 7 ISSUE 2A: SPECIAL ISSUE - HEALTH SCIENCE 2023
Publisher : Departement Research and Community Engagement Bina Sehat PPNI Institute of Health Science, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29082/IJNMS/2023/Vol7/Iss2A/526

Abstract

Glaucoma is a disease of the eye characterized by increased intraocular pressure, atrophy of the optic nerve papillae, and reduced vision. Glaucoma can be caused by systemic disease or local disease of the eye. One of the systemic disorders that can trigger glaucoma is diabetes mellitus (DM). The purpose of this study was to determine the relationship between the incidence of glaucoma and a history of diabetes mellitus at the KMU Madura eye clinic. This research was conducted using analytic observational method with a case-control design using a retrospective approach. The sample in this study was obtained by quota sampling technique with a total of 557 patients. Patient data was taken within a period of 12 months from January 2022 – December 2022. Based on the results of observational analysis, it was found that 203 patients (36.44%) had glaucoma with a history of diabetes mellitus, while 354 patients (63.56%) had glaucoma without a history of diabetes mellitus. The results of the Chi-Square test between the prevalence of Glaucoma and a history of Diabetes Mellitus showed a p value = 0.000 (p≤0.05) and the results of the Fisher test between each type of Glaucoma and a history of Diabetes Mellitus only Primary Open Angle Glaucoma only showed there was relationship with the value of p value = 0.004 (p <0.05). The results of this study can be concluded that there is a significant relationship between the prevalence of glaucoma and a history of diabetes mellitus.
PEMERIKSAAN DINI GOLONGAN DARAH PADA SANTRI PONPES TAHFIDZIL QURAN AL-ASROR M Shofwan Haris
JURNAL PARADIGMA (PEMBERDAYAAN & PENGABDIAN KEPADA MASYARAKAT) Vol 1 No 1 (2019): JURNAL PARADIGMA VOLUME 1 NOMOR 1 APRIL 2019
Publisher : STIKES NGUDIA HUSADA MADURA

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Abstract

Blood is one of the most important components in the body, considering its function as a means of transportation. Lack of blood in the body can spur a number of diseases starting from anemia, hypotension, heart attacks, and several other diseases. Law number 36 of 2009 concerning health states that a health service facility is a tool and / or place used to carry out promotional, preventive, curative and rehabilitative health service efforts which are carried out by the government, local government and / or the community (Kemenkes RI , 2015). Based on a survey through interviews with students of SMKN 2 Bangkalan that had been conducted, it was found that many students at SMKN 2 Bangkalan still did not know their blood type. The method used to carry out community service is by collecting data on the number of students at SMKN 2 Bangkalan, then conducting interviews with students about their blood group and then making a time contract with the students. The activity was continued with a blood group examination for santri santri who did not know their blood type. The participants of the activity were 37 students at SMKN 2 Bangkalan who took part in the blood group examination. While participating in the activities, the students were very enthusiastic about the activities being carried out. The results of the activities most of the gender of the students were male as many as 21 people (56.8%). And, most of the students' blood groups were O as many as 13 people (35.2%)