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All Journal Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Ophthalmologica Indonesiana
Ariesti, Andrini
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Computer Science & IT Health Professions Medicine & Pharmacology Public Health Social Sciences Other

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CORRELATION OF CENTRAL CORNEAL THICKNESS TO ACTUAL INTRAOCULAR PRESSURE IN MYOPIA PATIENTS Pandjaitan, Hadwer Wicaksono; Ariesti, Andrini
Majalah Oftalmologi Indonesia Vol 51 No 1 (2025): Ophthalmologica Indonesiana
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/journal.v51i1.101669

Abstract

Background : Central Corneal Thickness (CCT) is promote in the diagnosis and management of glaucoma, especially in myopic patients. Understanding the correlation between CCT and IOP (Intraocular Pressure) aids in glaucoma detection and control. The objective of this study is to determine the correlation between CCT and actual IOP in myopic patients. Methods : This research is an observational study with ethical committee approval, involving medical students from the Faculty of Medicine at Andalas University undergoing clinical clerkships at Dr. M Djamil Padang General Hospital. They were grouped into emmetropia, mild myopia, and moderate myopia. Data included visual acuity measurements, autorefraction, CCT measurements using OCT, and IOP with CCT correction. Samples with eye abnormalities, systemic conditions, myopia > 6D, a history of eye surgery, contact lens wear, and IOP > 21 mmHg were excluded. All data were analyzed statistically. Results : The study involved 78 eyes from 78 individuals, consisting of 26 eyes per group. The actual CCT and IOP values in mild myopia, moderate myopia and emmetropia are 506.31 ± 11,263 μm with 15.81 ± 1,234 mmHg, 533.96 ± 21,342 μm with 16.12 ± 1,336 mmHg, and 487.81 ± 28,272 μm with 15.35 ± 1.056 mmHg. There was a strong positive correlation between CCT and IOP (r=0.737, p=0.000), as well as a moderate negative correlation between CCT and actual IOP (r=-0.492, p=0.000). Conclusion : This research reveals a negative correlation between CCT and actual IOP in myopic patients, highlighting the importance of glaucoma screening for myopic patients due to their thinner corneas.
Screening Cataract and Other Visual Impairment by PELITA Cadre to Build Vision Center in Lima Puluh Kota Regency Ariesti, Andrini; Hendriati, Hendriati; Hidayat, Muhammad; Irayanti, Irayanti; Ilahi, Fitratul; Yuswir, Astria Rima Rara; Lonanda, Gama Agusto; Primasakti, Pattih; Roza, Silvia; Syafendra, Atika; Afelita, Tia; Putra, Heru Ardila; Suhery, Suhery; Irza, Metika Rahmasari; Lucyana, Lucyana; Maralaut, Azhardin; Zulferza, Jaka
Warta Pengabdian Andalas Vol 32 No 3 (2025)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.32.3.390-399.2025

Abstract

Eye diseases, particularly cataracts, are the leading cause of blindness worldwide. This community service program by the Department of Ophthalmology, Faculty of Medicine, Andalas University, was conducted at the Pangkalan Public Health Center, Lima Puluh Kota Regency, by empowering PELITA (Posyandu) cadres in early detection of cataracts. Methods included counseling, training, and eye examination simulations for 40 cadres, followed by community screening using visual acuity and anterior segment examinations. Evaluation was carried out with pre- and post-tests, satisfaction surveys, and follow-up on patients referred for surgery. The average cadre score improved from 68 (pre-test) to 74.5 (post-test), indicating increased knowledge. A total of 71 patients were screened, including 40 cataract and 8 pterygium cases; 26 cataract and 4 pterygium patients subsequently underwent surgery. Cadres reported high satisfaction with the training and expressed readiness to continue participation. This program demonstrates that cadre training is effective in improving early detection of cataracts and other visual impairments, and provides a foundation for establishing a Vision Center in Lima Puluh Kota.
THE EFFECT OF ORAL VITAMIN D ON TUMOR NECROSIS FACTOR-? EXPRESSION IN TRABECULAR MESHWORK OF WISTAR GLAUCOMA MODEL: Oral Presentation - Experimental Study - Resident ERINA, RIKHA; Ariesti, Andrini; Hendriati
Majalah Oftalmologi Indonesia Vol 49 No S2 (2023): Supplement Edition
Publisher : The Indonesian Ophthalmologists Association (IOA, Perhimpunan Dokter Spesialis Mata Indonesia (Perdami))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35749/vrszrr85

Abstract

Introduction & ObjectivesElevated intraocular pressure (IOP) is a risk factor for the development and progression of glaucomathat can induces inflammation in the trabecular meshwork through the production of proinflammatorycytokines such as TNF-?. Inflammation induce mechanical stress and changes in theextracellular matrix in the trabecular meshwork, resulting in hypertonicity and resistance toaqueous humor outflow. Vitamin D can modulate cytokine production by suppressing TH1 cellexpression and inducing TH2 cell expression. The production of pro-inflammatory cytokines can besuppressed by the presence of vitamin D. MethodsAn experimental study of 30 wistar glaucoma model were divided into 3 groups, non treatmentgroup ( A and B) and the oral vitamin D (1200 IU/kg/day) group (C) for 14 days. TNF-? expressionsin trabecular meshwork were measured by immunohistochemical staining. Group A was measuredon day 3, while group B and C were measured on day 14. The differences between the three groupswere analyzed statistically using one way ANOVA test. Significantly different if the p<0.05. ResultsThe mean expression of TNF- ? in the trabecular meshwork of wistar glaucoma model in group A, B,and C was 22,2 ± 2,51%, 39,1 ± 3.98%, 34.2 ± 3,19 % respectively. There was significantlydifference in TNF-? expressions between the three groups (p<0.001). ConclusionVitamin D per oral can decrease TNF-? expression in the trabecular meshwork of wistar glaucomamodel on day 14 . Studies in wistar and humans are still needed to assess the effect of vitamin D onothers pro-inflammatory cytokines in glaucoma.
Co-Authors Afelita, Tia Astria Rima Rara Yuswir ERINA, RIKHA Hendriati Hendriati, Hendriati Heru Ardila Putra Ilahi, Fitratul Irayanti, Irayanti Irza, Metika Rahmasari lonanda, Gama Agusto Lucyana Lucyana, Lucyana Maralaut, Azhardin Muhammad Hidayat Pandjaitan, Hadwer Wicaksono Primasakti, Pattih Roza, Silvia Suhery, Suhery Syafendra, Atika Zulferza, Jaka