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All Journal Jurnal Riset Biologi dan Aplikasinya Jurnal Medisains Kesehatan As-Shiha : Journal of Medical Research
Abeiasa, Muhammad Saka
Universitas Sumatera Barat
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Environmental Science Immunology & microbiology Medicine & Pharmacology Public Health

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Pengaruh Pemberian Ekstrak Pacar Kuku (Lawsonia inermis L) Untuk Penyembuhan Luka Bakar Pada Mencit Putih Elfia, Linda; Abeiasa, M Saka; Humaira, Vilma; Rahmi, Fatihatur
Jurnal Medisains Kesehatan Vol. 3 No. 2 (2022): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v3i2.251

Abstract

Burns are injuries caused by direct contact or exposure of the body to sources of heat, chemicals, electricity and radiation. Burns not only cause damage to the skin but can also affect the body's system. Therefore, burns require special attention in handling. Lawsonia inermis L. is a plant that contains compounds that play a role in wound healing such as flavonoids, saponins and tannins. This study aims to determine whether there is an effect of henna leaf extract on healing burns. Nail henna leaf extract was made by maceration using 96% ethanol as solvent. This study used male mice as test animals which were divided into 5 groups, the positive control group was not given treatment, the negative control group was given vaseline flavum and 3 groups were given henna leaf extract with concentrations of 20%, 40% and 60%. Burns were made by using preheated solder for 5 minutes. The intervention was carried out once a day. The results of the statistical analysis of the One Way ANOVA test showed that the concentration of fast burn healing was 40%.
Perbandingan Aktivitas Anti Bakteri Ekstrak Daun Pepaya (Carica Papaya L) Dan Daun Kelor (Moringa Oleifera L) Terhadap Bakteri Staphylococcus Aureus Abeiasa, M Saka; Gusnelti, Yesi; Warma Putri, Romi Yanti
Jurnal Medisains Kesehatan Vol. 3 No. 2 (2022): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v3i2.252

Abstract

This study aims to determine the comparison of papaya leaf extract (Caricapaya L) and Moringa leaf (Moringa oleifera L) against staphylococcus aureus bacteria. The type of research used is a laboratory experiment with a completely randomized design (CRD), using the nutrium agar method, namely using disk paper that already contains papaya leaf extract (Carica papaya L.) and Moringa leaf (Moringa oleifera L.) against staphylococcus aureus bacteria. the results of the inhibition zone of papaya leaf bacteria at a concentration of 25-100% experienced ups and downs, at a concentration of 25% with an average inhibition of 5.6mm and at a concentration of 50% increased with an average inhibition of 6mm then at a concentration of 75% decreased with an average of 5.8mm and at a concentration of 100% increased by an average of 6.6mm. Moringa leaves have the inhibitory activity of staphylococcus aureus bacteria from a concentration of 25% to 100% also experience an up and down phase, at a concentration of 25% with an average of 5.6 mm and at a concentration of 50% it increases with an average of 6.2 and at the concentration of 75% also increased with an average of 7 and the concentration of 100% decreased with an average of 6.5 so that Moringa leaves have an antibacterial inhibitory power. There is a difference between papaya leaf extract and Moringa leaf extract, namely at concentrations of 25%, 50% 75% and 100%
Perbandingan Aktivitas Daya Hambat Antibakteri Antara Ekstrak Daun Sirih Merah (Piper Crocatum Ruiz & Pav) Dengan Daun Sirih Hutan (Piper Aduncum L) Terhadap Streptococcus Mutans Abeiasa, M Saka; Humaira, Vilma; Ferdian, Heru
Jurnal Medisains Kesehatan Vol. 3 No. 1 (2022): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v3i1.258

Abstract

One of the diseases caused by Streptococcus mutans bacteria is dental caries. Dental caries is a condition where there is damage to the tooth-forming tissue structure caused by bacterial activity. The process of dental caries begins with the demineralisation of teeth by the presence of lactic acid and other organic acids that accumulate or accumulate on the surface of the teeth through plaque.This study aims to compare the antibacterial activity of red betel leaf extract (Piper crocatum Ruiz & Pav) and forest betel leaf extract (Piper aduncum L) against Streptococcus mutans bacteria, the cause of dental caries. The research method used was laboratory experiment with statistical analysis using One-Way ANOVA test and Post Hoc LSD test. The results showed that both extracts had antibacterial activity against Streptococcus mutans, with forest betel leaf showing higher activity than red betel leaf. Significant differences were seen at concentrations of 25%, 50%, 75%, and 100%. The forest betel leaf extract had a larger inhibition zone diameter compared to the red betel leaf extract. Nonetheless, both extracts were still less effective than the Amoxicillin control. In conclusion, red betel leaf extract and forest betel leaf extract have potential as antibacterial agents against Streptococcus mutans. However, forest betel leaf extract showed higher activity in inhibiting the growth of these bacteria compared to red betel leaf extract. Therefore, the use of forest betel leaf extract can be an effective alternative in the treatment of dental caries.
Perbandingan Aktivitas Antibakteri Ekstrak Bonggol Nanas (Ananas comosus L.) dan Getah Pepaya (Carica papaya) Terhadap Bakteri Stapylococcus Aureus Mossfika, Eldya; Abeiasa, M. Saka; Putra, Doli Juanda
Jurnal Medisains Kesehatan Vol. 5 No. 1 (2024): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v5i1.294

Abstract

Penelitian ini bertujuan untuk mengetahui perbandingan aktivitas antibakteri ekstrak limbah bonggol nanas (Ananas comosus L.) dan getah pepaya (Carica papaya) terhadap baktei Stapylococcus aureus. Jenis penelitian yang digunakan adalah eksperimen laboratorium dengan rancangan acak lengkap (RAL), menggunakan metode nutrium agar yaitu megunakan kertas disk  yang sudah terkandung  esktrak limbah bonggol nanas dan getah pepaya  terhadap bakteri Stapylococcus aureus dengan konsentrasi 25%, 50%, dan 75%. Hasil daya hambat pada getah pepaya mengalami naik turun pada  konsentrasi pada konsentrasi 25% dengan rata-rata daya hambat 5,5 mm, pada konsentrasi 50% dengan rata-rata daya hambat 3,4 mm, dan 75% dengan rata-rata daya hambat 4,2 mm. Pada ekstrak limbah bonggol nanas mengalami kanaikan pada setiap konsentrasi dengan rata-rata daya hambat pada konsentrasi 25% dengan rata-rata daya hambat 2,9mm, pada konsentrasi 50% dengan rata-rata daya hambat  3,2 mm, dan pada konsentrasi 75% dengan rata-rata daya hambat  5,6 mm. Dari data yang diperoleh menunjukan hasil terbaik terdapat pada ektrak bonggol nanas konsentrasi 75% dengan nilai rata-rata daya hambatnya 5,6 mm karna luasnya zona hambat yang tebentuk. Maka dapat disimpulkan bahwa ekstrak getah pepapya dan bonggol nanas berpotensi menghambat bakteri Stapylococcus aureus yang ditandai dengan terbentuknya zona hambat.
Evaluasi Penggunaan Obat Glimepirid Pada Pasen Diabetes Melitus Tipe 2 Di RS Tamar Medical Centre Pariaman Humaira, Vilma; Gusnelti, Yesi; Abeiasa, M. Saka; Fadya Syafitri, Aqilla
Jurnal Medisains Kesehatan Vol. 5 No. 1 (2024): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v5i1.340

Abstract

Evaluation of the use of diabetes mellitus type 2 drugs at Tamar Medical Center Pariaman Hospital aims to determine usage patterns and evaluate the rationality (appropriateness) of using antidiabetic drugs. The research method used is descriptive with direct data sampling. A total of 30 samples were evaluated, the conclusion of this research is that from the first ten points regarding the correct dose, from 30 respondents, 80.64% (25 people) had used the correct dose of medication and 19.36% (5 people) had not used the correct dose at Tamar Hospital. medical pariaman and from the second ten points about the right way to use it, from 30 respondents 59.31% (18 people) had the right way to use the drug glimepiride, 40.69% (12 people) did not use the medicine correctly and from the third ten points about the right time 85.62% (27 people) were on time when using glimepirid, 14.38% (3 people) were not using glimepiride on time)
PENGERUH WAKTU KERJA TERHADAP KADAR HEMOGLOBIN DAN JUMLAH SEL DARAH MERAH PETUGAS SHIFT MALAM SPBU JATI PARIAMAN Muhammad Saka Abeiasa
As-Shiha : JOURNAL OF MEDICAL RESEARCH Vol. 1 No. 1 (2020)
Publisher : Sekolah Tinggi Ilmu Kesehatan (STIKes) Piala Sakti Pariaman

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Based on reports from the World Health Organization (WHO), the prevalence of anemia in the world is still quite high with an incidence rate of 2.3 billion, in Asia it is known that the prevalence of anemia is still very high, it is known that 85% of anemia sufferers are women and children, about 50% of these events are iron deficiency anemia. This research uses descriptive analytic method using a cross sectional approach to see the relationship of events at one time. The study was conducted in March 2018 at the Pariaman city gas station. The sample was taken using a total sampling method with a total sample of 15 Jati gas station operators with night shift work. The data collection method begins with observing and interviewing the operator to get operator schedule data. Afterwards, each operator who is on a night shift is examined by taking a sample of peripheral blood through the fingertips. The blood obtained was analyzed using the Neubeur technique to see the number of red blood cells, while for Hb levels using the EasyTouch GCHb tool. From the results of the above table, it is known that the p value (0.00) shows that the time of night work has an influence on hemoglobin levels and the number of red blood cells in the Pariaman gas station. It can be concluded that there is a significant influence between the time of night work on hemoglobin levels and the number of red blood cells at the jati gas station night shift operator.
Perbandingan Efektivitas Antipiretik Ekstrak Etanol Daun Kapuk dan Daun Kembang Sepatu Pada Mencit Terinduksi Pepton Maharani, Silvia; Abeiasa, M. Saka; Yansen, Fatridha
Jurnal Medisains Kesehatan Vol. 6 No. 1 (2025): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v6i1.525

Abstract

Fever is a physiological response of the body to infection, characterized by an increase in temperature due to the activation of endogenous pyrogens. Herbal plants such as kapok (Ceiba pentandra) and hibiscus (Hibiscus rosa sinensis) are traditionally used as antipyretics due to their active compounds such as flavonoids, tannins, and saponins. This study aims to compare the antipyretic efficacy between ethanol extracts of kapok leaves and hibiscus in mice (Mus musculus) induced with fever using 10% peptone intravenously. The study design was a post-test only control group with 24 white male mice divided into three groups: P1 (negative control, only inducing peptone without treatment), P2 (induced by peptone and given kapok leaf extract 300 mg/kgBW), and P3 (induced by peptone and given hibiscus leaf extract 300 mg/kgBW). Body temperature was measured at 30 to 180 minutes after treatment. The results showed a decrease in average body temperature to 38.1°C at P2 and 36.7°C at P3, while P1's body temperature remained high above 39°C. One-Way ANOVA test showed significant differences between groups (p<0.05). Although both extracts showed significant antipyretic effects, hibiscus extract produced a greater decrease in temperature.
Co-Authors Agustri Gunawan, Ulfa Ardika, Eche Eldya Mossfika Elfia, Linda Endang Sari Fadya Syafitri, Aqilla Ferdian, Heru Gusnelti, Yesi Maharani, Silvia Putra, Doli Juanda Rahmat Yuza, Ibnu Rahmi, Fatihatur Vilma Humaira Warma Putri, Romi Yanti Yansen, Fatridha Yuza, Novendra