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Yansen, Fatridha
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Aktivitas Antibakteri Ekstrak Etanol Kulit Buah Manggis Terhadap Bakteri Staphylococcus Epidermis Humaira, Vilma; Abeiasa, M. Saka; Yansen, Fatridha
Jurnal Medisains Kesehatan Vol. 4 No. 1 (2023): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v4i1.143

Abstract

Manggis dapat digunakan untuk mengobati asam urat, diare, disentri dan sariawan. Senyawa kimia dalam manggis mungkin memiliki sifat antibakteri, seperti flavonoid, xanthones, tanin, terpenoid dan saponin. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri ekstrak etanol kulit manggis terhadap bakteri Staphylococcus epidermis. Penelitian ini menggunakan desain penelitian eksperimen laboratorium (real eksperimen) dan metode post test only control group design. Ekstrak kulit manggis adalah 5% b/v (b/v), 10% b/v, 20% b/v, 40% b/v, 60% b/v dan 80% b/v. Sampel yang digunakan adalah Staphylococcus epidermidis. Kesimpulan dari penelitian ini adalah ekstrak etanol manggis (Gracinia mangostana) pada konsentrasi 20% b/v, 40% b/v, 60% b/v, 80% b/v dan 100% dapat menghambat pertumbuhan Staphylococcus manggis. Diameter resistor adalah 18,4 mm, 19,6 mm, 20,4 mm, 21,4 dan 21,6 mm. dan konsentrasi ekstrak etanol manggis menunjukkan perbedaan pertumbuhan Staphylococcus epidermis. dimana p = 0,000, yang lebih kecil dari nilai default, yaitu p
Perbandingan Uji Efektivitas Antibakteri Ekstrak Lengkuas (Alpinia Galanga) Dan Kunyit (Curcuma Domestica Val) Terhadap Bakteri Staphylococcus Aureus Agustri Gunawan, Ulfa; Abeiasa, M Saka; Yansen, Fatridha
Jurnal Medisains Kesehatan Vol. 4 No. 2 (2023): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v4i2.204

Abstract

Lengkuas(Alpinia galanga)merupakan salah satu tanaman biofarmaka. Lengkuas mengandung senyawa metebolit sekunder seperti flavonoid, tanin, saponin yang memiliki daya hambat bakteri. Kunyit (Curcuma domestica Val) merupakan salah satu komoditas pertanian di Indonesia, memiliki kandungan kurkumin yang cukup tinggi yang mampu menghambat bakteri Staphylococcus aureus. Penelitian ini bertujuan untuk membandingkan efektivitas antibakteri ekstrak lengkuas (Alpinia galanga) dan ekstrak kunyit (Curcuma domestica Val) terhadap bakteri Staphylococcus aureus. Penelitian menggunakan eksperimen laboratorium dengan rancangan acak lengkap (RAL) menggunakan metode paper disc pada zona hambat. Hasil penelitian menunjukkan bahwa kedua ekstrak mempunyai daya hambat yang signifikan terhadap bakteri Staphylococcus aureus, dan tidak terdapat perbedaan yang signifikan antara kedua ekstrak. Studi ini menyoroti potensi kedua ekstrak dalam meningkatkan sifat antibakteri bakteri.
The POTENSI BAKTERI ASAM LAKTAT Lactobacillus fermentum DIISOLASI DARI IKAN BILIH ( Mystacoleucus padangensis ) DANAU SINGKARAK TERHADAP PERFORMA PRODUKSI DAN PENURUNAN KOLESTROL PUYUH PETELUR Setya Prima, Heppy; Susalam, Malikil Kudus; Fajri, Fadhli; Maulana, Fajri; Yansen, Fatridha
Jurnal Peternakan Borneo Vol. 3 No. 2 (2024): Jurnal Peternakan Borneo
Publisher : Pusat Penelitian dan Pengabdian Kepada Masyarakat Politeknik Negeri Tanah Laut

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34128/jpb.v3i2.36

Abstract

Bakteri Asam Laktat (BAL) akhir-akhir ini menjadi salah satu bagian dari pokok pembahsan bidang kesehatan, industri makanan, sains,.peternakan, pertanian. Penggunaan beberapa jenis BAL ini diketahui mempunyai manfaat yang  sangat bagus bagi ternak atau pada beberapa bahan pangan. Penelitian ini bertujuan untuk mengetahui interaksi antara dosis dan lama pemberian probiotik asal Ikan Bilih (M. padangensis) Danau Singkarak dalam mempengaruhi performa produksi dan menurunkan kadar kolesterol kuning telur puyuh. Metode yang digunakan adalah pemberian probiotik hasil isolasi kepada puyuh petelur menggunakan Rancangan Acak Lengkap (RAL) pola Faktorial 4 x 4 dengan 3 kali ulangan sesuai faktor A (dosis probiotik) dan faktor B (lama pemberian). Dosis probiotik yang diberikan adalah 0, 1, 2 dan 3 %, sedangkan lama pemberian adalah 10, 20, 30 dan 40 hari. Hasil menunjukkan pengaruh yang nyata (P<0,01) pada masing-masing faktor beserta nilai terbaik dimana pemberian dosis probiotik dan lama pemberian berpengaruh terhadap konversi ransum (17,11gr) pemberian dosis 3% dengan lama pemberian 30 hari, Produksi telur (73,88 %) pemberian dosis 3% dengan lama pemberian 20 hari, Berat telur (13,40 gr) pemberian dosis 3% dengan lama pemberian 20 hari, konversi ransum (2,21) pemberian dosis 3% dengan lama pemberian 30 hari dan kolestrol kuning telur (50,30 mg /dL) pemberian dosis 3% dengan lama pemberian 40 hari. Hasil menunjukkan terdapat interaksi antara dosis probiotik dan lama pemberian terhadap performa produksi dan penurunan kadar kolesterul puyuh petelur.
Learning Science for Pre-School and Elementary School Pupils Through Mini-Science Practicum at Rumah Pintar Mingguan Kreatif Ampang, Kuranji District, Padang yansen, fatridha
Pelita Eksakta Vol 8 No 01 (2025): Pelita Eksakta, Vol. 8, No. 1
Publisher : Fakultas MIPA Universitas Negeri Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/pelitaeksakta/vol8-iss01/203

Abstract

This activity aims to improve the ability and to increase the interest of children coming from low-income families at Rumah Pintar Mingguan Kreatif Ampang (RPM Ampang) to learn science through mini-science experiments. This practicum consists of two topics; the phenomenon of an erupting volcano and the inflation of a balloon without being blown up. This activity was attended by 31 pupils, and 5 RPM volunteers. The result of this community service activity is an increase in children's interest and motivation in the field of science, as well as an understanding of a topic through direct practicum using simple tools and materials to make learning more meaningful. In addition, RPM will make this mini science practicum activity a monthly routine activity in the RPM community with assistance from Universitas Sumatera Barat’s team to mentor their volunteers so that RPM can independently perform science experiments in the future. Keywords — Science experiment, Rumah Pintar, pre-school children, education disparity, chemistry
UJI AKTIVITAS ANTIBAKTERI EKSTRAK KULIT JERUK JESIGO  (Citrus nobilis Lour) TERHADAP BAKTERI Escherichia coli DAN Listeria monocytogenes Setya Prima, Heppy; Yansen, Fatridha
Jurnal Zarah Vol. 12 No. 1 (2024): Jurnal Zarah
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Listeria monocytogenes dan Escherichia  coli adalah bakteri penyebab berbagai infeksi pada manusia. Kulit jeruk JESIGO  (Citrus nobilis Lour) mengandung  senyawa kimia berupa flavonoid,  alkaloid,  saponin  dan  tanin yang  berfungsi  sebagai  antibakteri. Penelitian  ini  bertujuan  untuk  mengetahui  aktivitas ekstrak kulit jeruk JESIGO  (Citrus nobilis Lour) dalam menghambat pertumbuhan bakteri Escherichia coli dan  Listeria monocytogenes.  Penelitian ini merupakan eksperimental laboratorium  dengan metode  difusi  agar untuk mengetahui daya hambat terhadap bakteri Escherichia coli dan  Listeria monocytogenes melalui pembentukan zona inhibisi. Sampel  yang  digunakan adalah bakteri Escherichia coli dan  Listeria monocytogenes. Beberapa variasi konsentrasi ekstrak kulit jeruk JESIGO; 5%, 15%, 25%,  45%, digunakan dalam penelitian ini.  Amoxicilin  dan DMSO digunakan sebagai kontrol positif dan kontrol negatif. Berdasarkan hasil penelitian,  konsentrasi ekstrak kulit jeruk JESIGO konsentrasi 45% menunjukkan daya hambat terbaik terhadap E. coli O157 dengan diameter zona hambat sebesar 15,76 mm (kuat). Diameter zona hambat terbesar terhadap bakteri Listeria monocytogenes diperoleh dari ekstrak kulit jeruk JESIGO dengan kosentrasi 45% yaitu 19,98 mm (kuat). Hasil penelitian menunjukkan bahwa ekstrak kulit jeruk JESIGO  (Citrus nobilis Lour)  memiliki aktivitas antibakteri terhadap Escherichia coli dan  Listeria monocytogenes dalam kategori kuat.
PERBANDINGAN AKTIVITAS ANTI-HIPERURISEMIA EKSTRAK ETANOL SELEDRI (APIUM GRAVEOLENS L.) DAN DAUN SALAM (SYZYGIUM POLYANTHUM) PADA MENCIT YANG DIINDUKSI KAFEIN Yansen, Fatridha; Nanda Putra; Yesi Gusnelti; Heppy Setya Prima
Jurnal Zarah Vol. 13 No. 1 (2025): Jurnal Zarah
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Maritim Raja Ali Haji

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Abstract

Celery plants (Apium Graveolens L) and bay leaves (Syzygium polyanthum) have been used as alternative medicine to treat Hyperuricemia. This study aimed to determine the effectiveness of administration of extracts from celery plants and bay leafs to decrease uric acid levels in blood. This research used a post-test control group only design. A total of 24 male mice (randomly divided into 4 groups; P0, P1, P2 and P3). P0 was the control group (induced with caffeine at a dose of 0.5 mg/kgBW). P1 was induced with caffeine 0.5 mg/kgBW+celery extract 35 mg/kgBW, P2 was induced by caffeine 0.5 mg/kgBW+bay leaf extract 35 mg/kgBW and P3 was induced by caffeine + a combination of celery plant extract and bay leaves 35mg/kgBW. Uric acid levels were measured using an easy touch GCU meter device. The results showed that average of uric acid level for P0, P1, P2 and P4 were 7.1mg/dl; 4.9 mg/dl; 4 mg/dl; and 5.2 mg/dl, respectively. The most significant antihyperuricemia activity was demonstrated by administering 35 mg/kgBW of bay leaf extract. The One Way ANOVA analysis described that the administration of extract ethanol generated significant effects (p-value <0.05). Based on post hoc LSD analysis, it was found that the administration of ethanol extract from bay leaves showed significant differences compared to combination (celery + bay leaves) in lowering uric acid levels. Therefore, it was concluded extract from celery and bay leaves can be used to lower the level of uric acid
Edukasi Pemanfaatan Tanaman Obat Keluarga (Toga) Di Lingkungan Smp/Sma It Pondok Pesantren Sahabat Cendekia Pariaman Yansen, Fatridha; Mossfika, Eldya; Elfia, Linda
Jurnal Pengabdian Masyarakat Vol. 2 No. 1 (2024): Jurnal Pengabdian Masyarakat
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/2024.v2i1/378/5/juramas

Abstract

Medicinal plants particularly grown by family in their own garden namely “Tanaman Obat Keluarga” (TOGA) can be used to prevent disease, promote and improve health condition and cure disease. In addition, TOGA also contributes in increasing family prosperity since medicinal plants have significant economic value. Female students known as “santriwati” who stay in Islamic boarding schools are vulnerable to diseases due to lack of hygiene and high residential density. Skin diseases, diarrhea, flu and fever are some of those diseases that students prone to be infected. Considering their conditions, which stay apart from their families, hence, independence and sufficient knowledge regarding health aspects are very necessary. This community service activity aimed to educate female students regarding the use of various types of medicinal plants (TOGA) to maintain health and treat various diseases. This socialization activity was carried out in the Islamic boarding school of the Sahabat Cendekia - Middle School/Senior High School, District of Central Pariaman, Pariaman City with 87 targeted female students. Santriwari are informed about the material related to the types of TOGA that can be planted in Islamic boarding school environments, the benefits of TOGA and how to process TOGA so that it can be used as an agent for disease prevention, health maintenance and illness treatment
Probiotic and Its Fundamental Role In Gastrointestinal Health: A Literature Review Yansen, Fatridha
Majalah Kedokteran Andalas Vol. 46 No. 3 (2023): Supplementary July 2023
Publisher : Faculty of Medicine, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/mka.v46.i11.p1851-1861.2024

Abstract

The gastrointestinal tracts are hosts to a wide variety of microorganisms known as intestinal microbiota. This gut microbiome may get disrupted that will influence the human health. Probiotics can restore the balance of gut microbiota by changing its composition and promoting its stability. Objective: This review aims to compile the role of probiotics in maintaining gastrointestinal health based on evidence-based through the modulation of the human gut microbiome.  Method: This article is structured based on a literature review method by collecting and reviewing papers published in PubMed, Scopus, ScienceDirect, Springer, and Google Scholar.  Results: The administration of probiotics have successfully shown evidenced beneficial health effects to prevent or treat for several main these several diseases including diarrhea, lactose intolerance and intestinal bowel diseases. Conclusion: Probiotics have been demonstrated to play key functions in the digestive system and to considerably reduce the symptoms of a variety of illnesses.
Effect of drying methods on total flavonoid content of Scurrula ferruginea (Jack) Danser (Loranthaceae) leaf extracts parasitizing jengkol (Pithecellobium jiringa) Yansen, Fatridha; Mossfika, Eldya; Prima, Heppy Setya
Science, Technology, and Communication Journal Vol. 6 No. 1 (2025): SINTECHCOM Journal (October 2025)
Publisher : Lembaga Studi Pendidikan dan Rekayasa Alam Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59190/stc.v6i1.339

Abstract

Scurrula ferruginea (Benalu) is a hemiparasitic plant with potential as a raw material for traditional medicine due to its high flavonoid content. The concentration of flavonoids is substantially determined by the specific drying technique applied. Studies investigating the use of the stir-frying method remain limited, and there is no standardized protocol has yet been established to recommend an appropriate method for preserving the total flavonoid content in S. ferruginea leaves. This study aims to compare the total flavonoid content (TFC) in ethanol extracts of Benalu leaves on the Jengkol dried using three different methods: air-drying, oven-drying, and stir-frying drying. All samples were subsequently powdered and subjected to maceration using ethanol solvent, followed by analysis of their total flavonoid content using spectrophotometry UV-Vis at maximum wavelength at 431 nm. Statistical analysis of one-way ANOVA showed that different drying methods generated significant effects on TFC level of Benalu leaves extracts with significance value = 0.001 (p-value <= 0.05). The results indicated that air-drying yielded the highest flavonoid content with 7.37 ppm, followed by stir-frying (4.93 ppm) and oven-drying (2.88 ppm). These findings highlight the critical importance of selecting an appropriate drying method to preserve flavonoid levels, thereby enhancing the pharmacological efficacy and quality of herbal products derived from S. ferruginea leaves.
Perbandingan Aktivitas Antidiare Ekstrak Etanol Daun Seledri Dan Biji Pinang Pada Mencit Terinduksi Minyak Jarak Putri, Sami Mardiah; Yansen, Fatridha; Humaira, Vilma
Jurnal Medisains Kesehatan Vol. 6 No. 1 (2025): Jurnal Medisains Kesehatan
Publisher : Universitas Sumatera Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59963/jmk.v6i1.522

Abstract

Diarrhea remains a significant health problem in Indonesia, especially among children. The use of medicinal plants as alternative therapy continues to grow due to their milder side effects compared to synthetic drugs. This study aimed to compare the antidiarrheal activity of ethanol extracts of celery leaves (Apium graveolens L.) and areca nuts (Areca catechu L.) on mice (Mus musculus L.) induced with castor oil. The experiment was conducted in a laboratory using a post-test only control group design involving 27 male mice divided into three groups: control, celery leaf extract (20 mg/kgBW), and areca nut extract (350 mg/kgBW). One Way ANOVA showed significant differences among groups in defecation frequency and diarrhea onset (p < 0.05; p = 0.000). The mean defecation frequency was 16 times in the control group, 13 in the celery extract group, and 8 in the areca extract group. Diarrhea onset occurred at 69.25 minutes, 51.75 minutes, and 37.5 minutes, respectively. The areca nut extract at 350 mg/kgBW was the most effective antidiarrheal agent, reducing defecation frequency and delaying diarrhea onset. This effect is attributed to secondary metabolites such as flavonoids, tannins, saponins, and alkaloids, which which act as natural antidiarrheals
Co-Authors Abeiasa, Muhammad Saka Agustri Gunawan, Ulfa Eldya Mossfika Elfia, Linda Fadhli Fajri fajri maulana Heppy Setya Prima Maharani, Silvia Nanda Putra Putri, Sami Mardiah Raden Mohamad Herdian Bhakti Vilma Humaira Yesi Gusnelti