Article Per Year (5 Year)
p-Index From 2020 - 2025
1.908
P-Index
This Author published in this journals
All Journal Folia Medica Indonesiana Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Jurnal SainHealth JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Media Gizi Kesmas Ophthalmologica Indonesiana
Prastyani, Reni
Department Of Ophthalmology, Faculty Of Medicine, Universitas Airlangga, Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Other

Published : 11 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 11 Documents
Search

 1   2 
The CD4 Count and Viral Load Differences in HIV Patients with and without Infectious Posterior Uveitis at a Tertiary Hospital in Indonesia Hidayat, Shofa Annesa; Zuhria, Ismi; Arfijanto, Muhammad Vitanata; Prastyani, Reni
Current Internal Medicine Research and Practice Surabaya Journal Vol. 6 No. 2 (2025): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v6i2.65918

Abstract

Introduction: The human immunodeficiency virus (HIV) compromises the immune system, making the monitoring of cluster of differentiation (CD4) counts and viral loads critical for assessing disease progression and opportunistic infection risks. Eye-related manifestations, such as uveitis, are common among HIV patients. The purpose of this study was to investigate the differences in CD4 count and viral load between HIV patients with infectious posterior uveitis and those without at Dr. Soetomo General Academic Hospital, Surabaya, Indonesia. Methods: A retrospective study with an analytical observational design was conducted using the medical records of 75 HIV patients. The examined variables included CD4 count and viral load as independent variables, alongside the incidence and absence of infectious posterior uveitis as dependent variables. The inclusion criteria were HIV patients with regular follow-ups, thereby excluding those with irregular follow-ups. The analysis used the Mann-Whitney test, with p<0.05 indicating a statistically significant difference. Results: All 75 samples met the inclusion criteria for analysis. The majority of the patients were male (64%) and within the age range of 31 to 40 years (44%). Patients with infectious posterior uveitis had significantly lower CD4 counts (p<0.05) compared to those without the disease. However, no significant differences in viral loads (p>0.05) were observed between patients with posterior uveitis and those without. Conclusion: CD4 counts differ significantly between patients with infectious posterior uveitis and those without, while viral loads show no considerable differences.   Highlights: 1. This study highlights the differences in cluster of differentiation (CD4) lymphocyte count and viral load between HIV patients with infectious posterior uveitis and those without. 2. The findings may provide new insights into the immunological mechanisms underlying infectious posterior uveitis in persons living with HIV. 3. This work contributes to determining the factors that affect the development of infectious posterior uveitis and explores the potential use of CD4 lymphocyte count and viral load as biomarkers for the diagnosis and management of the disease.
Co-Authors Aghnaita, Safira Amelia Rahmah Kartika Anas Jatikusuma Atina Yustisia Lestari Delfitri Lutfi Dinda Zhafira Fariani Syahrul Firmansjah, Muhammad Hasna Shahida Amatlulloh Hidayat, Shofa Annesa Indriaswati, Dyah Kusworini Joni Susanto, Joni Kurniawati, Dian Prasasti Lely Retno W Maftuchah Maftuchah Muhammad Valeri Alhakiim Muhammad Vitanata Arfijanto, Muhammad Vitanata Nerissa Tamara Putri Nur Fitriana Corprianti Marchilia Prastiya Indra Gunawan Riza Noviandi Rozalina Loebis, Rozalina Safaryna, Alifia Merza Soelistijo, Soebagijo Adi Sunny Mariana Samosir Tjujitno, Aurellia Valmai Zuhria, Ismi