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All Journal Jurnal Manajemen Kesehatan Yayasan RS.Dr. Soetomo Jurnal SainHealth Jurnal Medik Veteriner JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL Media Gizi Kesmas Ophthalmologica Indonesiana Folia Medica Indonesiana
Prastyani, Reni
Department Of Ophthalmology, Faculty Of Medicine, Universitas Airlangga, Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Penetrating Ocular Injury Management in Intraocular Foreign Body (IOFB) and Traumatic Cataract Putri, Nerissa Tamara; Firmansjah, Muhammad; Prastyani, Reni
Folia Medica Indonesiana Vol. 58, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Highlight: • The management of penetrating ocular injury with IOFB and traumatic cataracts needs a thorough examination of the mechanism of injury, location, size, and composition of IOFB. • Endophthalmitis, retinal detachment, and development of PVR are potentially vision-threatment. Abstract: Most IOFB are metallic and found in males of productive age as a consequence of work-related accidents. A 45-year-old man complained of sudden blurred vision in the left eye (3/60 pinhole 5/12) after getting hit by a foreign body when cutting grass with a lawn mower. Anterior segment examination revealed a 10 mm long, one-plane, straight, full thickness, already sutured inferonasal corneal laceration, inferonasal traumatic iridectomy size 3x7 mm, and opaque lens. Head CT-scan revealed opacity with metallic density intraocularly. Ultrasonography revealed an echogenic lesion, particle-shaped with 100% RCS complex density, located at the inferonasal of the vitreous cavity. Focal laser photocoagulation was performed preoperatively because there was a tear at the superonasal of the retina. The patient underwent cataract extraction, intraocular lens implantation, vitrectomy, and IOFB extraction in a one-step procedure. IOFB was found at the inferonasal side of a vitreous cavity with size 3 x 1 mm, metallic, and not attached to the retina. Silicon oil tamponade was used as a precaution because there were retinal tears. Postoperatively, the left eye's visualacuity was 5/20. After 6 months, the silicon oil was evacuated and the visual acuity became 5/8.5.
UV-A–based intervention for mitigating myopia progression via retinal dopaminergic pathways in rabbits Aritonang, Christina; Irwanto; Prastyani, Reni
Jurnal Medik Veteriner Vol. 9 No. 1 (2026): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol9.iss1.2026.71-84

Abstract

The global rise in myopia, particularly among children and young adults, has stimulated increasing interest in environmental and light-based preventive strategies. This study investigated the protective effects of ultraviolet-A (UV-A) light exposure on myopia progression in a form-deprivation model and explored its potential mechanism via dopaminergic retinal signaling. In this experimental study, form-deprivation myopia (FDM) was induced in rabbits, which were randomly assigned to either a control group (n = 7) or a UV-A–treated group (375 nm, 12 h/day for 5 days; n = 6). Axial length, refraction, and ocular surface safety (Schirmer’s test and clinical observations) were evaluated before and after treatment. Retinal tissues were analyzed for tyrosine hydroxylase (TH) and dopamine receptors (D₁R and D₂R). Axial elongation was assessed within and between groups. UV-A–treated eyes demonstrated a shorter axial length and a greater hyperopic shift compared with controls (17.72 ± 0.14 mm vs. 23.12 ± 2.34 mm, p = 0.001; +4.58 ± 0.66 D vs. +2.64 ± 1.41 D, p = 0.001). Schirmer’s test revealed no significant differences (p = 0.40). TH and D₂R expression levels were significantly higher in the UV-A group (p = 0.013 and p = 0.009, respectively). Limitations of the study include the short experimental duration, small sample size, and the absence of a UV dose–response analysis. Overall, UV-A light exposure showed potential in inhibiting ocular axial elongation and reversing myopic shifts in a form-deprivation model, possibly through activation of retinal dopaminergic pathways, highlighting UV-A as a promising light-based intervention for myopia control.
Co-Authors Aghnaita, Safira Alhakiim, Muhammad Valeri Amatlulloh, Hasna Shahida Aritonang, Christina Atina Yustisia Lestari Fariani Syahrul Firmansjah, Muhammad Hasna Shahida Amatlulloh Hidayat, Shofa Annesa Indriaswati, Dyah Kusworini IRWANTO Jatikusuma, Anas Joni Susanto, Joni Kurniawati, Dian Prasasti Lely Retno W Lutfi, Delfitri Maftuchah Maftuchah Muhammad Valeri Alhakiim Muhammad Vitanata Arfijanto, Muhammad Vitanata Nerissa Tamara Putri Noviandi, Riza Nur Fitriana Corprianti Marchilia Prastiya Indra Gunawan Putri, Nerissa Tamara Rahmah Kartika, Amelia Rozalina Loebis, Rozalina Safaryna, Alifia Merza Samosir, Sunny Mariana Soelistijo, Soebagijo Adi Tjujitno, Aurellia Valmai Zhafira, Dinda Zuhria, Ismi