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All Journal Jurnal Fitofarmaka Indonesia Window of Health : Jurnal Kesehatan Jurnal Abdi Insani Jurnal Pengabdian Masyarakat Sasambo Jurnal Masyarakat Madani Indonesia
Atmaja, Ratih Feraritra Danu
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences

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PEMBERDAYAAN MASYARAKAT DESA AWILA KECAMATAN MOLAWE DALAM BENTUK PEMERIKSAAN URINE RUTIN SERTA PELATIHAN PEMBUATAN JUS ALBEDO SEMANGKA SEBAGAI AGEN DETOKSIFIKASI GINJAL Orno, Theosobia Grace; Usman, Julianti Isma Sari; Atmaja, Ratih Feraritra Danu; Yuniarty, Tuty; Hasan, Aswiro; Sarita, Sultina
Jurnal Pengabdian Masyarakat Sasambo Vol 5, No 2 (2024): Mei
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jpms.v5i2.1487

Abstract

Kemandirian masyarakat merupakan salah satu tujuan program pemberdayaan masyarakat dalam bidang kesehatan. Desa Awila merupakan salah satu desa di Kecamatan  Molawe Kabupaten Konawe Utara yang memiliki masalah pada kesehatan ginjal. Kegiatan ini bertujuan untuk melakukan pemeriksaan urine rutin sebagai pemeriksaan laboratorium dasar fungsi ginjal, mengedukasi masyarakat tentang pentingnya menjaga kesehatan ginjal serta melatih masyarakat untuk secara mandiri membuat dan mengonsumsi jus albedo semangka yang terbukti secara ilmiah dapat meningkatkan laju filtrasi glomerulus ginjal. Hasil kegiatan pengabdian kepada masyarakat menunjukkan terdapat beberapa parameter pemeriksaan urine rutin yang abnormal diantaranya proteinuria sebanyak 69%, leukosituria dengan persentase 44%, hematuria dan glukosuria berturut-turut sebesar14% dan 6%. Terdapat peningkatan pengetahuan masyarakat pasca edukasi sebesar 92% disertai komitmen masyarakat untuk secara mandiri menerapkan pola konsumsi jus albedo semangka sehari-hari.  
Glomerular Filtration Rate in Prediabetic Subjects in Kendari City Orno, Theosobia Grace; Atmaja, Ratih Feraritra Danu; Supiati, Supiati; Hasan, Aswiro
Window of Health : Jurnal Kesehatan Vol 7 No 2 (April 2024)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/woh.vi.917

Abstract

Prediabetes is a condition of impaired blood glucose metabolism. However, it does not yet meet the criteria for diabetes mellitus, characterized by impaired fasting blood glucose (FBG) levels and the Oral Glucose Tolerance Test (OGTT). Chronic glucose intolerance can increase the workload of the kidney glomerulus in the filtration process and the tubules in the reabsorption process. The research aims to assess the Glomerular Filtration Rate (GFR) in prediabetic subjects in Kendari. This type of analytical observational research with a case-control design. The total sample was 90 samples consisting of 45 non-diabetic samples as the control group and 45 prediabetic samples as the case group. Characteristic data is presented as a frequency distribution and test data for differences between the control group and cases using an independent t-test with statistical test results said to be significant if the p-value is less than 0.05. The research results showed that the frequency distribution of subjects in the control group and cases based on gender was dominated by women, with the most extensive age range being 36-55 years. The FBG variable in the control group had a mean of 94±5.31 mg/dL, and in the case group, 110±8.09 mg/dL. The OGTT value in the control group was 118±12.78 mg/dL, and the case group was 139±23.90 mg/dL. The results of the calculation of the GFR showed a mean of 98.63±14.28 mL/min/1.73 m2 in the control group and 50.10±16.34 mL/min/1.73 m2 in the case group, different significant (p equal 0.000). There was a significant difference between GFR in the control group and the prediabetes case group. The results of the GFR assessment in the prediabetes group showed a mild decrease in renal function.
PEMBERDAYAAN MASYARAKAT SEBAGAI UPAYA PROMOTIF DAN PREVENTIF SINDROM METABOLIK PADA MASYARAKAT MELALUI PROGRAM MINCEU ANTI-MEARO Yuniarty, Tuty; Atmaja, Ratih Feraritra Danu; Orno, Theosobia Grace; Sari, Julianti Isma; Fauzi, Ahmad Zil; Putra, Ahmat Rediansya
Jurnal Abdi Insani Vol 12 No 7 (2025): Jurnal Abdi Insani
Publisher : Universitas Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/abdiinsani.v12i7.2629

Abstract

Infectious diseases remain a major public health concern due to their high morbidity and mortality rates, including conditions such as cardiovascular diseases, cancer, chronic respiratory diseases, and diabetes mellitus. Cardiovascular disease and diabetes are strongly associated with central obesity, dyslipidemia, elevated fasting blood glucose, and hypertension. Metabolic syndrome is defined as a constellation of complex metabolic abnormalities that significantly increases the risk of developing cardiovascular disease and type II diabetes mellitus. The key components implicated in the pathogenesis of metabolic syndrome include hypertension, central obesity, insulin resistance, and atherogenic dyslipidemia. This study aimed to educate the community about metabolic syndrome while simultaneously conducting early detection. The screening procedures included measurements of blood pressure, waist circumference, blood glucose levels, the measurement of total cholesterol, triglycerides, and low density lipoprotein (LDL) levels was performed using the Point of Care Testing (POCT) method. A total of 52 respondents participated in this activity, consisting of 57.7% (n=30) females and 42.3% (n=22) males. The results indicated that 92.3% (n=48) had normal blood glucose levels, 100% (n=52) had normal total cholesterol, and 21.2% (n=11) had normal LDL levels. Normal blood pressure was observed in 34.6% (n=18), while 67.3% (n=35) were found to have central obesity. Overall, 9.6% (n=5) of respondents were diagnosed with metabolic syndrome, whereas 90.4% (n=47) were not. Most respondents demonstrated metabolic risk factors such as hypertension, central obesity, and elevated LDL levels, despite having normal blood glucose and total cholesterol. These findings underscore the importance of continuous public health education and targeted interventions to prevent and reduce the prevalence of metabolic syndrome in the community.
Pengaruh Ekstrak Pogostemon cablin Benth terhadap Interleukin-6, Glukosa Darah, Hemoglobin dan Hematokrit pada Tikus Wistar yang Diinduksi Dietilnitrosamin Atmaja, Ratih Feraritra Danu; Yuniarty, Tuty; Misbah, Sitti Rachmi; Malik, Handayani
Jurnal Fitofarmaka Indonesia Vol 11, No 1 (2024): JURNAL FITOFARMAKA INDONESIA
Publisher : Faculty of Pharmacy, Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jffi.v11i1.1092

Abstract

Mortality and morbidity rates of hepatocellular carcinoma continue to rise worldwide. The role of inflammation, regulation of glucose metabolism, and anemia is widely studied concerning the development and life expectancy of patients with hepatocellular carcinoma. In several cancers, efforts to develop Pogostemon cablin benth plant potential drug candidates for hepatocellular carcinoma have been carried out at metabolomic, proteomic, and molecular levels. However, no studies have been found regarding the study of anti-inflammatory effects, metabolism, and anemic conditions of Pogostemon cablin benth intervention in hepatocellular carcinoma. This study is a pre-post experimental in-vivo study aimed at looking at the ability of Pogostemon cablin benth extract against interleukin-6 (IL-6) as an inflammatory marker, blood glucose levels as a marker of metabolic regulation and hemoglobin and hematocrit levels at as markers of anemia in hepatocellular carcinoma. A model of hepatocellular carcinoma was performed in 25 peritoneal-induced diethylnitrosamine-induced Wistar rats. The mice were divided into five groups, namely group 1 (K1), group 2 (K2), group 3 (K3), positive control (KP), and negative control (KN). Pogostemon cablin benth ethanol extract was administered orally to mice K1 40mg/kg body weight; K2:80mg/kg rat body weight; K3:120mg/kg body weight, while the positive control group was given Sorafenib. Interleukin-6 levels were measured using the enzyme-linked immunoassay principle, while glucose, hemoglobin, and hematocrit levels were measured using the enzymatic principle of glucose dehydrogenase-flavin adenine dinucleotide (GDH-FAD). The study showed no difference in blood glucose levels of mice between pre- and post-induction diethylnitrosamine. Induction of diethylnitrosamine obtained significantly led to a significant decrease in hemoglobin levels (15.54 g/dl ±1.28 vs. 14.31 g/dl ±1.11) and hematocrit (45.83% ±3.77 vs 42.20% ±3.25) levels between pre and post-induction. Mice in group 1 (K1) showed a significant increase in blood glucose levels between pre and post-oral Pogostemon cablin benth extract (p<0.05). There was no significant difference in hemoglobin and hematocrit levels in the treatment group between pre-intervention Pogostemon cablin benth extract. However, KN that did not receive Pogostemon cablin benth extract intervention significantly decreased hemoglobin and hematocrit levels (p<0.01). Decreased levels of the pro-inflammatory cytokine IL-6 occurred in K2 (p<0.05) after receiving oral Pogostemon cablin benth extract intervention. Based on this study, Pogostemon cablin benth extract may decrease IL-6 levels and is thought to influence hemoglobin and hematocrit levels in diethylnitrosamine-induced Wistar rats.
PEMBERDAYAAN MASYARAKAT DESA AWILA KECAMATAN MOLAWE DALAM BENTUK PEMERIKSAAN URINE RUTIN SERTA PELATIHAN PEMBUATAN JUS ALBEDO SEMANGKA SEBAGAI AGEN DETOKSIFIKASI GINJAL Orno, Theosobia Grace; Usman, Julianti Isma Sari; Atmaja, Ratih Feraritra Danu; Yuniarty, Tuty; Hasan, Aswiro; Sarita, Sultina
Jurnal Pengabdian Masyarakat Sasambo Vol. 5 No. 2 (2024): Mei
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jpms.v5i2.1487

Abstract

Kemandirian masyarakat merupakan salah satu tujuan program pemberdayaan masyarakat dalam bidang kesehatan. Desa Awila merupakan salah satu desa di Kecamatan  Molawe Kabupaten Konawe Utara yang memiliki masalah pada kesehatan ginjal. Kegiatan ini bertujuan untuk melakukan pemeriksaan urine rutin sebagai pemeriksaan laboratorium dasar fungsi ginjal, mengedukasi masyarakat tentang pentingnya menjaga kesehatan ginjal serta melatih masyarakat untuk secara mandiri membuat dan mengonsumsi jus albedo semangka yang terbukti secara ilmiah dapat meningkatkan laju filtrasi glomerulus ginjal. Hasil kegiatan pengabdian kepada masyarakat menunjukkan terdapat beberapa parameter pemeriksaan urine rutin yang abnormal diantaranya proteinuria sebanyak 69%, leukosituria dengan persentase 44%, hematuria dan glukosuria berturut-turut sebesar14% dan 6%. Terdapat peningkatan pengetahuan masyarakat pasca edukasi sebesar 92% disertai komitmen masyarakat untuk secara mandiri menerapkan pola konsumsi jus albedo semangka sehari-hari.  
Pemeriksaan Sedimen Urine Sebagai Upaya Deteksi Dini Kejadian Batu Ginjal Masyarakat Desa Awila Kabupaten Konawe Utara Orno, Theosobia Grace; Fauzi, Ahmad Zil; Usman, Julianti Isma Sari; Atmaja, Ratih Feraritra Danu; Yuniarty, Tuty; Rosanty, Anita
Jurnal Masyarakat Madani Indonesia Vol. 3 No. 2 (2024): Mei
Publisher : Alesha Media Digital

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59025/js.v3i2.209

Abstract

Batu ginjal merupakan salah satu utama masalah kesehatan ginjal di dunia termasuk Indonesia. Penegakan diagnosa batu ginjal secara laboratorium klinis dilakukan melalui pemeriksaan sedimen urine. Kegiatan ini bertujuan untuk deteksi dini kejadian batu ginjal masyarakat desa Awila kecamatan Molawe sesuai dengan keluhan masyarakat yang merujuk  pada gangguan fungsi ginjal. Hasil pemeriksaan sedimen urine menunjukkkan mayoritas masyarakat mengalami batu ginjal dengan variasi jenis batu kalsium oksalat, kalsium fosfat maupun kristal asam urat selain adanya sel epitel abnormal sebagai indikasi infeksi saluran kemih. Intervensi berupa edukasi person to person bagi masing-masing masyarakat sesuai hasil pemeriksaan. Diharapkan agar masyarakat lebih meningkatkan self awareness terhadap kesehatan ginjal. Peran pihak puskesmas diharapkan dapat membantu dalam penegakan diagnosa lebih lanjut disertai terapi sesuai gejala klinis  dan  hasil  pemeriksaan laboratorium medis.
Co-Authors Anita Rosanty, Anita Hasan, Aswiro Malik, Handayani Misbah, Sitti Rachmi Orno, Theosobia Grace Putra, Ahmat Rediansya Sari, Julianti Isma Sarita, Sultina Supiati Supiati Theosobia Grace Orno Tuty yuniarty, Tuty Usman, Julianti Isma Sari Zil Fauzi, Ahmad