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All Journal Althea Medical Journal MNJ (Malang Neurology Journal) JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indian Journal of Forensic Medicine & Toxicology AKSONA
Ardhi, Mohammad Saiful
Department Of Neurology, Faculty Of Medicine, Universitas Airlangga; Dr. Soetomo General Academic Hospital, Surabaya, Indonesia
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience Public Health

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Epidemiologic Profile of Ischemic Stroke Patients with Dyslipidemia in Dr. Soetomo General Academic Hospital Patient Prakoso, Raditya Ardra Putra; Ardhi, Mohammad Saiful; Thamrin, Husin; Setyowatie, Sita
AKSONA Vol. 5 No. 1 (2025): JANUARY 2025
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/aksona.v5i1.64275

Abstract

Highlight: This study provides insights into the epidemiologic profile of ischemic stroke patients with dyslipidemia in Dr. Soetomo General Academic Hospital. The majority of patients had hypertension, the most common comorbidity with low HDL-C levels Most patients showed moderate stroke severity and high levels of consciousness, with a majority proportion demonstrating recovery.   ABSTRACT Introduction: Ischemic stroke is a major medical issue, especially in individuals with dyslipidemia, as it can elevate both the likelihood and severity of stroke incidents. This study is essential due to the rising prevalence of stroke and limited data regarding ischemic stroke patients with dyslipidemia in Indonesia. Understanding these traits is important for enhancing preventative and treatment strategies. Objective: This study intended to assess the epidemiologic profile of ischemic stroke patients with dyslipidemia in a tertiary hospital in Indonesia. Methods: This descriptive study assessed 116 medical records of ischemic stroke patients with dyslipidemia admitted to Dr. Soetomo General Academic Hospital in Surabaya, Indonesia, from January to June 2023. The collected data encompassed demographics, comorbidities, lipid profiles, and clinical outcomes. Dyslipidemia was defined based on the PERKENI guidelines, and stroke severity was assessed using the GCS and NIHSS scales. Results: The majority of ischemic stroke patients with dyslipidemia (77.6%) had low HDL-C levels. There were 64 males and 52 females; most of them were between the ages of 56 and 65. Hypertension was the most common comorbidity (64.7%), followed by diabetes (39.7%), heart disease (12.9%), and obesity (11.2%). Of 40 NIHSS-assessed patients, 26 had moderate, 8 mild, 2 moderate-to-severe, and 4 severe strokes. The majority of patients (70.7%) recovered. Conclusion:The majority of dyslipidemia-related ischemic stroke patients, aged 56 to 65, had low HDL-C levels. Hypertension was the main comorbidity, with many experiencing their first stroke. Most patients had high consciousness, moderate stroke severity, and showed improvements.  
Profile of Risk Factors for Hemorrhagic Stroke in Patients at the Neurological Inpatient Installation of Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, from January to June 2022 Surdji, Almuta'Aaliyati Nur; Ardhi, Mohammad Saiful; Parenrengi, Muhammad Arifin; Setyowatie, Sita
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 16 No. 2 (2025): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V16I22025.148-154

Abstract

Highlights: Modifiable risk factors of hemorrhagic stroke were hypertension, DM, dyslipidemia, and smoking history. Non-modifiable risk factors of hemorrhagic stroke were gender and age.   Abstract Introduction: Stroke is one of the top ten causes of death worldwide. Hemorrhagic strokes are more common in men, and their risks increase with age. This study aimed to determine the risk factor profile for hemorrhagic stroke (intracerebral hemorrhage/ICH and subarachnoid hemorrhage/SAH) among patients in the neurological inpatient installation of Dr. Soetomo General Academic Hospital, Surabaya, from January to June 2022. Methods: This study employed a descriptive observational method, utilizing secondary data obtained from the medical records of patients with hemorrhagic stroke at Dr. Soetomo General Academic Hospital, Surabaya, from January to June 2022. The data calculations were performed using the International Business Machines Corporation (IBM) Statistical Package for Social Sciences (SPSS) version 26. The variables examined in this study included the type of hemorrhagic stroke, non-modifiable risk factors, modifiable risk factors, and other risk factors. Results: In total, 50 medical records were retrieved. The type of hemorrhagic stroke was dominated by intracerebral hemorrhage. Among them, 29 (58%) patients were males, 35 (70%) patients were 46-65 years old, 41 (82%) patients had hypertension, 16 (32%) patients had diabetes mellitus (DM), 19 (38%) patients had dyslipidemia, 8 (16%) patients had a history of smoking, 14% of patients had aneurysms. Only 2% of patients had arteriovenous malformation (AVM). Conclusion: The dominant risk factors for hemorrhagic stroke were gender, age 46-65 years old, and hypertension.
RISK FACTOR PROFILE OF ISCHEMIC STROKE PATIENTS Divastuti, Kedyatasya Rae Fahirah; Setyowatie, Sita; Suryantoro, Satriyo Dwi; Ardhi, Mohammad Saiful
MNJ (Malang Neurology Journal) Vol. 11 No. 2 (2025): July
Publisher : PERDOSSI (Perhimpunan Dokter Spesialis Saraf Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.mnj.2025.011.02.16

Abstract

Background: Stroke remains a leading cause of disability and mortality, with ischemic stroke being the most prevalent type. The high incidence of ischemic stroke is associated with various risk factors, both modifiable and non-modifiable. In Indonesia, limited public awarness and data availability contribute to the increasing burden of ischemic stroke. Objective: This study aims to identify the risk factor profile of ischemic stroke patients in the Inpatient Unit of Universitas Airlangga Hospital, Surabaya. Methods: This retrospective descriptive study utilized secondary data from medical records of patients diagnosed with ischemic stroke between January and December 2023. The variables analyzed included age, gender, hypertension, diabetes mellitus, dyslipidemia, and smoking habits. A total sampling method was applied to the medical records of ischemic stroke patients admitted to the Inpatient Unit of Universitas Airlangga Hospital, Surabaya, during the specified period. Results: Based on 412 collected medical records, the results showed that the most prevalent non-modifiable risk factor was male gender (55.1%), followed by age 45–60 years (44.42%). Meanwhile, the most common modifiable risk factor was dyslipidemia (71.04%), followed by hypertension (66.5%), diabetes mellitus (33.33%), and smoking habit (25.97%). Conclusion: Dyslipidemia was the most prevalent risk factor, followed by hypertension, male gender, age 45–60 years, diabetes mellitus, and smoking habit.
Correlation Between Lactate Dehydrogenase Levels and National Institutes of Health Stroke Scale Scores at the Onset of Acute Ischemic Stroke Fikriyah, Lathifatul; Ardhi, Mohammad Saiful; Setyowatie, Sita
Althea Medical Journal Vol 12, No 4 (2025)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/amj.v12n4.4391

Abstract

Background: In acute ischemic stroke, reduced oxygen supply may trigger metabolic acidosis and cellular injury. Lactate dehydrogenase (LDH), as an intracellular enzyme, helps generate energy by converting pyruvate to lactate in glycolysis. This study aimed to examine the correlation between serum LDH levels and the National Institutes of Health Stroke Scale (NIHSS) score at the onset of treatment among patients with acute ischemic stroke.Methods: This analytical observational study used cross-sectional design, involving patients with acute ischemic stroke hospitalized at Dr. Soetomo Surabaya Hospital, Indonesia, between February and May 2023. Participants were selected using consecutive sampling. Serum LDH levels and NIHSS score were measured upon admission. The correlation between LDH levels and NIHSS score was analyzed using the Spearman test, with statistical significance set at p<0.05. Results: A total of 30 patients were included, of whom 16 (53.3%) were male. A significant correlation was found between LDH levels and NIHSS scores (p=0.001). The correlation coefficient (r=0.785) indicated a strong positive correlation between serum LDH levels and stroke severity.Conclusions: This study demonstrates a strong positive correlation between LDH levels and NIHSS scores at the onset of acute ischemic stroke treatment. These findings suggest that LDH may serve as a practical early biomarker for assessing stroke severity. Integrating LDH measurement into initial evaluation may facilitate faster risk stratification and support timely clinical decision-making. Further studies with larger sample sizes are needed to validate its prognostic role in routine practice.
Co-Authors Achmad Firdaus Sani, Achmad Firdaus Aisyah Rizki Ramadhani Asra Al Fauzi Citra Amaniah Anhar Dedy Kurniawan Divastuti, Kedyatasya Rae Fahirah Fikriyah, Lathifatul Hermawan Susanto Kusuma, Nabila Divandra Mohammad Pratama Jauhar Putra Muh. Wildan Yahya Parenrengi, Muhammad Arifin Perdana, Philips Carel Prakoso, Raditya Ardra Putra Puji Lestari Puspa Wardhani, Soebagijo Adi Sihotang, Marselia Febriyanti Sita Setyowatie Subur Prajitno Sudibyo, Devi Ariani Surdji, Almuta'Aaliyati Nur Suryantoro, Satriyo Dwi Thamrin, Husin Triagung Arif Pratama Widodo Widodo Yetti Hernaningsih