<![CDATA[ABSTRACT Pulmonary tuberculosis (TB) is an infectious disease that is still a public health problem, especially in developing countries, including Indonesia. The problems faced relate to disease, discovery, treatment, and also treatment failure. The aim of this study was to determine whether there was a relationship between respondent characteristics and biochemical assessment and the incidence of tuberculosis. This research uses a quantitative cross sectional method with purposive sampling technique. The research results were obtained from 76 respondents, most of whom did not experience pulmonary TB 46 (60.5%), most of them were of productive age 52 (68.4%), male 43 (56.6%), highly educated 40 (52, 6%), good knowledge 56 (73.7%), sputum BTA (+) 54 (71.1%), normal hemoglobin level 40 (52.6%), normal leukocytes 59 (77.6%) and normal platelets 65 (85.5%). There is a relationship between age (p-value = 0.045), gender (p-value = 0.032), education (p-value = 0.013), knowledge (p-value = 0.000), sputum BTA (p-value = 0.001), levels hemoglobin (p-value = 0.000), leukocyte levels (p-value = 0.007), platelet levels (p-value = 0.021) with the incidence of pulmonary TB. Knowledge is the variable most related to the incidence of pulmonary TB (p-value 0.001 and OR=10.105) Keywords: Tuberculosis, Biochemistry, Determinants, Respondents ABSTRAK Tuberkulosis (TB) paru merupakan penyakit menular yang masih menjadi masalah kesehatan masyarakat khususnya di negara berkembang, termasuk Indonesia. Tujuan dari penelitian ini adalah untuk mengetahui apakah ada hubungan antara karakteristik responden dan penilaian biokimia dengan kejadian tuberkulosis. Penelitan ini menggunkan metode kuantitatif cross sectional dengan Teknik purposive sampling. Hasil penelitian didapatkan dari 76 responden sebagian besar tidak mengalami kejadian TB paru 46 (60,5%), sebagian besar berumur produktif 52 (68,4%), berjenis kelamin pria 43 (56,6%), berpendidikan tinggi 40 (52,6%), berpengetahuan baik 56 (73,7%), sputum BTA (+) 54 (71,1%), kadar hemoglobin normal 40 (52,6%), leukosit normal 59 (77,6%) dan trombosit normal 65 (85,5%). Ada hubungan umur (p-value = 0,045), jenis kelamin (p-value = 0,032), pendidikan (p-value = 0,013), pengetahuan (p-value = 0,000), sputum BTA (p-value = 0,001), kadar hemoglobin (p-value = 0,000), kadar leukosit (p-value = 0,007), kadar trombosit (p-value = 0,021) dengan kejadian TB paru. Pengetahuan menjadi variabel yang paling berhubungan dengan kejadian TB paru (p- value 0,001 dan OR=10,105 Kata Kunci: Tuberkulosis, Biokimia, Determinan, Responden]]>
