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All Journal Indonesian Journal of Global Health research Jurnal Pengabdian kepada Masyarakat Nusantara Jurnal Farmasi Jurnal Farmasi dan Sains Indonesia (JFSI) SITAWA : Jurnal Farmasi Sains dan Obat Tradisional JURNAL KESEHATAN YAMASI MAKASSAR Jurnal Kesehatan Kartika
Adiningsih, Retnowati
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TINGKAT KEPATUHAN MINUM OBAT ANTIDIABETES PASIEN DIABETES MELITUS TIPE II DI PUSKESMAS KARTASURA SUKOHARJO Ifki Isnaini; Adiningsih, Retnowati; Anita Mursiany
Jurnal Kesehatan Yamasi Makassar Vol. 8 No. 2 (2024): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v8i2.339

Abstract

Diabetes mellitus (DM) is a serious long-term (or chronic) condition that occurs when there is an increase in glucose levels in the blood because the body cannot produce enough of the insulin hormone, or cannot use the insulin it produces effectively. The aim of this study was to determine the level of compliance with taking oral antidiabetic medication in patients with type II diabetes mellitus at the Kartasura Sukoharjo Community Health Center. The research method uses descriptive quantitative with prospective data collection. The research was conducted at the Kartasura Sukoharjo Community Health Center in December 2023 - January 2024. The instrument used was MARS-5 which consists of 5 questions that describe the patient's level of medication adherence. The sampling technique used purposive sampling (non probability sampling) of 120 samples. Based on the research results obtained, it can be concluded that the level of compliance with taking antidiabetic medication for type II diabetes mellitus patients is in the high level of compliance category with 9 respondents (7.5%), the medium level of compliance category is 111 respondents (92.5%), category low compliance level of 0 respondents (0%).
Hubungan Kepatuhan Penggunaan Obat dengan Keberhasilan Terapi Antihipertensi di Instalasi Rawat Jalan Puskesmas Gajahan Surakarta Kartika Sari, Mutiara; Adiningsih, Retnowati; hartono
JURNAL KESEHATAN KARTIKA Vol. 17 No. 2 (2022): Jurnal Kesehatan Kartika
Publisher : Faculty of Health Science and Technology, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkkes.v17i2.237

Abstract

Tingginya angka kejadian hipertensi di Indonesia tidak diikuti dengan kepatuhan pasien dalam mengkonsumsi obat. Pengukuran tingkat kepatuhan pada penelitian sebelumnya dari 50 pasien hipertensi yang tidak patuh sebanyak 35 pasien. Penentu keberhasilan terapi yaitu adanya kepatuhan penggunaan obat. Tingkat kepatuhan rendah menyebabkan masalah seperti peningkatan angka penyakit kronis dan komplikasinya. Riskesdas tahun 2018 prevalensi hipertensi di Indonesia adalah 34,1%. Pada tahun 2019 Puskesmas Gajahan Surakarta menduduki peringkat ke-delapan dengan jumlah pasien hipertensi terbanyak yaitu 1.583 orang. Penelitian ini bertujuan untuk mengetahui hubungan tingkat kepatuhan dan keberhasilan penggunaan obat pada pasien hipertensi rawat jalan di Puskesmas Gajahan Surakarta. Penelitian ini bersifat retrospektif. Teknik sampling dilakukan dengan purposive sampling. Pengambilan data menggunakan kuesioner ASK-12 pada pasien hipertensi. Hasil penelitian kepatuhan penggunaan obat antihipertensi menunjukkan pasien dengan kepatuhan tinggi sebanyak 57% sedangkan kepatuhan rendah sebanyak 43%. Hasil penelitian tingkat keberhasilan tekanan darah terdapat 45% pasien yang berhasil dan 55% pasien tidak berhasil. Hasil analisis uji chi-square menunjukkan bahwa variabel tekanan darah sistolik di dapatkan nilai P value = 0,000 (P<0,05) dan variabel tekanan darah diastolik di dapatkan nilai P value = 0,000 (P<0,05). Kesimpulan terdapat hubungan yang signifikan antara kepatuhan penggunaan obat dengan keberhasilan terapi antihipertensi di instalasi rawat jalan Puskesmas Gajahan Surakarta.
Hubungan Tingkat Pengetahuan dengan Kepatuhan Penggunaan Obat Anti Tuberkulosis Pada Pasien Penderita Tuberkulosis Di Rumah Sakit Umum Pusat Surakarta Tyas, Jatining; Murtisiwi, Lusia; Adiningsih, Retnowati
JURNAL KESEHATAN KARTIKA Vol. 17 No. 2 (2022): Jurnal Kesehatan Kartika
Publisher : Faculty of Health Science and Technology, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkkes.v17i2.240

Abstract

Tingkat kepatuhan pasien tuberkulosis paru dalam meminum obat anti tuberkulosis masih rendah. Berdasarkan penelitian di BKPM Pati tingkat kepatuhan pasien TB paru sebesar 26% (Dhewi, 2011) di Puskesmas Umbulsari sebesar 44,2% (Fauziyah, 2016). Salah satu faktor yang menjadi penyebab ketidakpatuhan adalah keterbatasan pengetahuan mengenai penyakit TB. Penelitian ini bertujuan untuk mengetahui hubungan tingkat pengetahuan dengan kepatuhan penggunaan OAT pada pasien penderita TB. Penelitian ini menggunakan rancangan studi cross sectional. Penentuan sampel menggunakan teknik purposive sampling. Besar sampel yang digunakan minimal 105 responden. Instrumen penelitian ini menggunakan kuesioner pengetahuan yang telah diuji validitas dan reliabilitas oleh Febriyanti (2020) dan kuesioner Medication Adherence Report Scale (MARS) yang telah diuji validitas dan reliabilitas oleh Zuhra (2019). Hasil penelitian menunjukkan pasien dengan pengetahuan baik sebesar 50,9% pengetahuan cukup sebesar 42,5% dan pengetahuan kurang sebesar 6,6%. Pasien dengan kepatuhan tinggi sebesar 87,7% dan kepatuhan rendah sebesar 12,3%. Uji analisis hubungan pengetahuan dengan kepatuhan penggunaan obat yang dilakukan dengan chi square menunjukkan adanya hubungan antara pengetahuan dengan kepatuhan didapatkan nilai P value = 0,004 (P<0,05). Hasil ini menunjukkan bahwa terdapat hubungan yang bermakna antara pengetahuan dengan kepatuhan penggunaan obat anti tuberkulosis.
Evaluasi Kepatuhan Penggunaan Obat Antidiabetik Oral Pada Pasien Rawat Jalan Diabetes Melitus Tipe 2 Di Rumah Sakit Universitas Sebelas Maret: EVALUATION OF ADHERENCE TO THE USE OF ORAL ANTIDIABETIC DRUGS IN OUTPATIENTS WITH TYPE 2 DIABETES MELLITUS AT THE UNS HOSPITAL Latipah, Ayu; Murtisiwi, Lusia; Adiningsih, Retnowati
JURNAL KESEHATAN KARTIKA Vol. 17 No. 2 (2022): Jurnal Kesehatan Kartika
Publisher : Faculty of Health Science and Technology, University of Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26874/jkkes.v17i2.242

Abstract

Diabetes mellitus is a chronic disease that can cause complications, both microangiopathy and macroangiopathy if not treated properly. The success of diabetes mellitus therapy is influenced by patient compliance in drug use. The purpose of this study was to determine adherence to the use of oral antidiabetic drugs in outpatients with type 2 diabetes mellitus at Sebelas Maret University Hospital. This research is a non-experimental descriptive research. Sampling was done by purposive sampling in accordance with the inclusion criteria and exclusion criteria that have been determined. Compliance data retrieval using the Medication Adherence Report Scale questionnaire in Indonesian which has been tested for validity and reliability by Alfian (2017) which is distributed to patients. Data collection techniques were direct interviews with patients and filling out a questionnaire for patient data and the MARS-5 medication adherence questionnaire. Data analysis was carried out descriptively by describing the patient's characteristics. Analysis of the level of compliance in this study using a total scoring questionnaire MARS-5. This research has obtained a research permit with an ethical feasibility letter No: 788/VI/HREC/2022. Data collection was carried out in June-July 2022. The results showed that from 205 respondents, the level of adherence to the use of oral antidiabetic drugs included a low adherence rate of 50.2% and a high adherence rate of 49.8%.
Identifikasi Drug Related Problems (DRPs) Pada Kasus Diare Anak Pasien Rawat Jalan di UPT. Puskesmas X Kudus Setyoningsih, Heni; Latifah, Siti Nor; Adiningsih, Retnowati; Wijaya, Hasty Martha
Jurnal Farmasi & Sains Indonesia Vol 7 No 2 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no2p78-85

Abstract

Diarrhea is still a health problem in developing countries, including Indonesia. Diarrhea is a potential endemic disease of Extraordinary Events (KLB) accompanied by death that often occurs in Indonesia. Drug Related Problems (DRPs) are unwanted events experienced by patients and actually or potentially interfere with the desired therapeutic results. This study aims to determine Drug Related Problems (DRPs) including drug selection, drug form, dose selection, duration of treatment and drug interactions in cases of diarrhea in outpatients at UPT. X Kudus District Health Center for the period January - June 2020. Non-experimental research with observational methods conducted by collecting data retrospectively and analyzed descriptively quantitatively. The sampling technique used was total population sampling by purposive sampling with clear and complete inclusion criteria for outpatient medical records with a diagnosis of diarrhea aged 0-11 years at UPT. X Kudus District Health Center for the period January - June 2020. The results of the study obtained 79 patients who met the inclusion criteria. This study showed that the most common types of DRPs were drug interactions (12%), drug selection (10%), and dose selection (8%). The amount of drug use did not significantly affect the incidence of DRPs in the drug interaction category (P = 0.019). The results showed that there had been DRPs in pediatric diarrhea patients at UPT. X Kudus District Health Center for the period January - June 2020.
Evaluasi Penyimpanan Obat Di Apotek K-24 Setiabudi Solo Mursiany, Anita; Wahyu Ichsanudin, Muhammad; Adiningsih, Retnowati
SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Vol. 4 No. 2 (2025): SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Publisher : LPPM Akademi Farmasi Imam Bonjol Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62018/sitawa.v4i2.153

Abstract

Apotek merupakan sarana pelayanan kefarmasian yang dilakukan oleh apoteker yang telah berkembang dari product oriented menjadi patient oriented. Apotek memiliki fungsi pengelolaan sediaan farmasi terutama bagian penyimpanan. Penyimpanan di Apotek K-24 Setiabudi belum sesuai dengan FEFO sehingga ada obat kadaluarsa berdasarkan stock opname tahun 2024. Penyimpanan obat prekursor dan LASA masih berdekatan yang dapat berdampak terhadap keselamatan pasien yaitu pemberian obat yang tidak tepat. Tujuan penelitian ini untuk mengevaluasi penyimpanan obat pada Apotek K-24 Setiabudi Solo dengan Petunjuk Teknis Standar Pelayanan Kefarmasian di Apotek Tahun 2019 dan Peraturan Menteri Kesehatan No. 34 Tahun 2021 Tentang Standar Pelayanan Kefarmasian Klinik. Jenis penelitian ini adalah penelitian deskriptif observasional. Penelitian dilakukan pada tempat penyimpanan obat baik gudang maupun etalase display obat di Apotek K-24 Setiabudi Solo menggunakan lembar checklist pada semua bentuk sediaan dan semua golongan obat untuk mengetahui kesesuian penyimpanan dengan standar. Hasil checklist dipresentasikan dalam kategori nilai kriteria. Hasil penelitian ini menunjukkan kesesuaian untuk aspek sarana dan prasarana 78,6% masuk dalam kategori baik menggambarkan kelengkapan dan kelayakan sarana prasarana di apotek serta aspek penyimpanan 86,4% masuk kategori sangat baik menggambarkan kesesuaian sistem penyimpanan. Kedua hasil penelitian tersebut merupakan bukti bahwa penyimpanan obat telah sesuai dengan petunjuk teknis yang berlaku
Evaluation of the Rationality of Antibiotic Use in Child Diarrhea Patients in the Inpatient Care Installation Anggraini, Truly; Adiningsih, Retnowati; Logarithm, Khoirun Nisa
Indonesian Journal of Global Health Research Vol 7 No 4 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i4.6440

Abstract

According to WHO and UNICEF, diarrheal disease occurs around 2 million cases and 1.9 million children die each year with a prevalence of 78% in developing countries. The treatment used is antibiotics. Irrational use of antibiotics can cause less effective treatment, decreased drug safety levels, high treatment costs and increased resistance. The purpose of this study was to evaluate the rationality of antibiotic use in pediatric diarrhea patients at UNS Hospital using the Gyssens method for the period January - September 2023. This study was conducted as an observational study with a descriptive design with retrospective sampling, the sample of this study was 80 patients and included in the inclusion category of 33 samples, then a descriptive analysis was carried out using the Gyssens assessment. The reference used is the Indian guidelines Academy of Pediatrics (IAP) 2022, DIH, MIMS, and UNS Hospital Drug Formulary. Data collection began with observation of medical records of pediatric diarrhea patients at UNS Hospital. The research data was obtained from UNS Hospital medical records for the period January - September 2023, then analyzed using the Gyssens method which was categorized as 0 - 6 descriptively and presented in the form of a percentage.This study shows the results of the rationality of antibiotics for pediatric diarrhea patients in the inpatient department of UNS Hospital using the Gyssens method for the period January - September 2023 proving that 71.73% of patients received rational antibiotic therapy (category 0), as many as 28.27% of patients received irrational antibiotic therapy including 10.87% category IVC, namely there are cheaper alternatives, 6.53% category IIIB, namely the duration of antibiotic use is too short, 10.87% category IIB, namely the interval of antibiotic administration is not appropriate.
ANALISIS TINGKAT KEPUASAN PASIEN TERHADAP PELAYANAN KEFARMASIAN DI APOTEK TASIKMADU KARANGANYAR Anisa; Hartono; Adiningsih, Retnowati
Jurnal Kesehatan Yamasi Makassar Vol 9 No 2 (2025): Jurnal Kesehatan
Publisher : Akademi Farmasi Yamasi Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59060/jurkes.v9i2.389

Abstract

Patient satisfaction is an important and crucial indicator of service quality and pharmacy performance. Therefore, pharmacies must be oriented towards patient satisfaction and patient safety in every service provided. Continuous improvement needs to be done in order to maintain service quality. Periodic and continuous evaluation is a must carried out by pharmacies. The purpose of this study was to determine the performance of pharmacies in their pharmaceutical services to patients. This research design is descriptive quantitative with observational methods through prospective studies. The population and sample were customers who had experienced the services of Tasikmadu Pharmacy from February - March 2025 by giving questionnaires to 100 patients of Tasikmadu Pharmacy. Measurement of satisfaction based on servqual dimensions, namely assurance, empathy, responsiveness, physical facilities (tangible), and reliability. Data analysis using Likert scale. Based on the results of the analysis, the level of satisfaction with services in the guarantee dimension at Tasikmadu Pharmacy is very satisfied with a score of 90.91%, the empathy dimension is very satisfied (90.5%), the responsiveness dimension (89.5%), the physical facilities dimension (88.43%), and the reliability dimension (87.17%). The achievement of a satisfaction score of 89.30% in the five dimensions of service indicates that the services at the Tasikmadu Pharmacy are considered very satisfying by patients. However, it is necessary for pharmacies to continue to strive to improve their performance in providing services to patients, especially in the reliability dimension.
Pengaruh Kombinasi Emulgator CMC dan Tween 80 Terhadap Stabilitas Fisik Emulsi Minyak Ikan Adiningsih, Retnowati
Jurnal Farmasi (Journal of Pharmacy) Vol. 3 No. 1 (2014): Jurnal Farmasi (Journal of Pharmacy), October 2014
Publisher : Jurnal Farmasi (Journal of Pharmacy)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Cod-liver oil emulsion in standard formula using gum arabic as emulsifying agent is considered to be “true” emulsifier. The disadvantage of gum arabic is it cannot be stored in along time because the emulsifier effect will vanish, so it has to be combined with other emulsifying agent such as CMC and Tween 80. The aim of the experiment was to study the influence of CMC and Tween 80 emulsifiers combination on physical stability of cod liver oil emulsion and the optimal concentration of CMC and Tween 80 emulsifiers to prepare a stable cod liver oil emulsion, indicated by there was no significant damage of the emulsion during the experiment. The experiment used 4 formulas which contain emulsifiers combinations: 0,25% CMC; 0,25% CMC : 10% Tween 80; 0,25% CMC : 20% Tween 80; 20% Tween 80. The observation of emultion stability includes emulsion type, separation percentage at room temperature, at 40° - 50°C temperature, at 3000 rpm centrifugally, viscosity and particle size determination. The result of the experiment indicated there was various stability of cod liver oil emulsion in each emulsifier combination. The statistic result indicated that CMC 0,25% had significant influence on separation percentage at room temperature, at 40° - 50°C, 3000 rpm centrifugally, viscosity and particle size of cod liver oil. Emulsion with emulsifiers combination of 0,25% CMC : 20% Tween 80 was the most stable emulsion because at the separation percentage examination, the viscosity and particle size had the best physical stability compared with other formula.
HUBUNGAN KARAKTERISTIK DENGAN PENGETAHUAN TENAGA TEKNIS KEFARMASIAN DALAM REKONSTITUSI INJEKSI ANTIBIOTIK DI RAWAT INAP RS UNS Dwi Utari, Septiyani; Adiningsih, Retnowati
Jurnal Farmasi (Journal of Pharmacy) Vol. 11 No. 2 (2022): Jurnal Farmasi (Journal of Pharmacy), October 2022
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/j5ww7h55

Abstract

Reconstitution is the process of mixing the solvent medium into a dry powder mass to produce suspended or dissolved substances. Mixing injection drugs, including reconstitution of antibiotic injections, should be formulated by pharmacists, in fact all of them are still made by non-pharmaceutical health workers, apart from lack of correlation, it also gives the impression that the hospital is violating the rules. To prevent errors in compounding, pharmaceutical staff attend aseptic technique training to minimize contamination during compounding. The purpose of this study was to examine the relationship between characteristics and knowledge of pharmaceutical technicians in reconstitution of antibiotic injections at UNS Hospital inpatients. Descriptive research with correlation studies the relationship between two or more variables. Data collection is done.total.sampling. Retrieval of data used a questionnaire and processed with SPSS 21.0 For.Windows application. The results of this study indicate that the characteristics include gender, p value = 0.014, at = 0.05 (p<α), education p value = 0.961, at = 0.05 (p>α), length of work p value = 0.719, at =0.05 (p>α). The conclusion obtained is that there is no significant relationship between education and length of work. There is a significant relationship between gender in the knowledge of pharmaceutical technicians in reconstitution of antibiotic injections at UNS Hospital inpatients.
Co-Authors Aminuyati Andini, Elisabeth Septia Anggraini, Truly Anggraini, Truly Dian Anisa Anita Mursiany Anita Mursiany, Anita Dwi Utari, Septiyani Dzaki Fikri Firdaus Bakri Hapsari, Eliza Dian Hartono Hartono Hasty Martha Wijaya Ifki Isnaini Iwan Setiawan Kartika Sari, Mutiara Latifah, Siti Nor Latipah, Ayu Logarithm, Khoirun Nisa Murtisiwi, Lusia Setyoningsih, Heni Tyas, Jatining Wahyu Ichsanudin, Muhammad