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All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Jurnal Online Mahasiswa (JOM) Bidang Kedokteran Jurnal Kesehatan Melayu JBN (Jurnal Bedah Nasional) Acta Biochimica Indonesiana Bioscientia Medicina : Journal of Biomedicine and Translational Research Health and Medical Journal Unri Conference Series: Community Engagement Bioscientia Medicina : Journal of Biomedicine and Translational Research JMMR (Jurnal Medicoeticolegal dan Manajemen Rumah Sakit)
TB Odih Rhomdani Wahid
Universitas Riau
Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Pancreas-Sparing Mucosectomy for a Complex Gastric Duplication Cyst: A Case Report Filza Rifqi Aufa Aslam; Ismar Ibrahim; Tubagus Odih Rhomdani Wahid; Andrea Valentino; Salamullah; Indrajaya
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 9 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i9.1371

Abstract

Background: Gastric duplication (GD) is a rare congenital anomaly, representing 2–9% of all gastrointestinal duplications. These embryologic abnormalities are typically managed by complete surgical resection due to the risk of complications, including malignancy. However, this standard approach becomes perilous when the duplication cyst is intimately adherent to vital organs. We present a case where a large gastric duplication cyst was inseparable from the pancreas, necessitating a deviation from standard management. Case presentation: An 8-month-old female infant presented with a four-month history of non-bilious vomiting and progressive abdominal distension. A palpable, cystic, 8x5 cm mass was identified in the left upper abdomen. Abdominal ultrasound revealed a loculated, septated cystic lesion, and a barium study demonstrated a significant filling defect on the greater curvature of the stomach. Initial management was delayed as the family sought alternative medicine. Surgical exploration revealed a large gastric duplication cyst arising from the greater curvature, which was found to be densely adherent to the body and tail of the pancreas. To avoid catastrophic pancreatic injury, a complete resection was abandoned in favor of a pancreas-sparing mucosectomy. The entire mucosal lining of the duplication was excised, and the shared muscular wall was preserved and repaired. Postoperatively, the patient had a transient ileus but recovered well, with complete resolution of symptoms. At an 11-day follow-up, she was thriving, feeding well, and had gained significant weight. Histopathology confirmed a benign gastric duplication cyst. Conclusion: This case highlights that for complex gastric duplication cysts where resection would endanger vital structures, complete mucosal excision is a safe, effective, and organ-preserving surgical alternative. This technique successfully mitigates the risks of both the untreated anomaly and iatrogenic surgical complications, underscoring the importance of surgical judgment and adaptability in managing rare congenital anomalies.
Penanaman Mangrove di Kawasan Ekoeduwisata Bandar Bakau Dumai Sebagai Upaya Pencegahan Masalah Kesehatan Syahputra, Febrian; Soripada, Timotius Agung; Wahid, Tubagus Odih Rhomdani; Adli, Muhammad Faiz; Ramadhanti, Annisa Salsabila; Adinda, Irviana Tri; Adawiyah, Rabiatul; Putri, Reta Amelia; Nabila, Nabila; Indarwati, Citra Lestari; Desvira, Melinda; Aleem, Zellina Shaqueela; Khaifah, Noor Zakiyah; Vidi, Darrel Vania Putri
Unri Conference Series: Community Engagement Vol 7 (2025): Seminar Nasional Pemberdayaan Masyarakat
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat Universitas Riau

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31258/unricsce.7.165-168

Abstract

Dumai City is located on the east coast of Sumatra, facing the Strait of Malacca. Dumai's coastal location puts it at risk of disasters such as tidal flooding. Tidal flooding is a phenomenon caused by sea tides exceeding normal levels, resulting in flooding. This disaster can be very detrimental because it causes infrastructure damage and can even lead to loss of life. Furthermore, this disaster can also significantly impact the health of coastal communities. One cause is dirty floodwater mixed with waste, which can have negative health effects, especially on skin health due to direct contact with polluted water. Some examples of problems that arise include itching, irritation, bacterial or fungal infections, and other skin diseases. Various efforts can be made to prevent this incident. One effort that can be done is to prevent tidal flooding by planting mangroves and educating coastal communities about various skin problems that arise from tidal flooding. Planting mangroves is one form of prevention against seawater overflowing onto land. Mangrove ecosystems are forests that grow in coastal areas with brackish or salty water. Mangroves have strong roots that extend into the mud, providing a remarkable natural defense against tidal flooding and coastal erosion. Therefore, actions such as planting mangrove seedlings in areas adjacent to the sea can be taken as a form of environmental awareness and to anticipate tidal flooding. Based on these issues, a community service activity was carried out, namely planting 12 mangrove seedlings as a form of effort to prevent skin diseases and tidal flooding.
Putative and pretreatment drug resistance mutations in reverse transcriptase gene among untreated chronic hepatitis B patients at Arifin Achmad Regional District Hospital, Riau, Indonesia Arfianti, Arfianti; Djojosugito, Fauzia Andrini; Maisaroh, Maisaroh; Asputra, Hendra; Sari, Dita Kartika; Wahid, Tubagus Odih Rhomdani
Acta Biochimica Indonesiana Vol. 5 No. 1 (2022): Acta Biochimica Indonesiana
Publisher : Indonesian Society for Biochemistry and Molecular Biology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32889/actabioina.68

Abstract

Background: Mutations within the hepatitis B virus (HBV) reverse transcriptase (RT) gene have been associated with drug resistance against nucleos(t)ide analogs (NAs). Objective: This study aimed to identify mutations in the RT gene among patients with chronic hepatitis B (CHB) before receiving antiviral therapy and its relationship with the HBV genotypes. Methods: A total of 26 HBV DNA was extracted from the blood plasma of CHB patients. HBV RT gene was amplified and sequenced using the Sanger dideoxy sequencing method. The HBV genotype was determined through phylogenetic analysis using the Maximum Likelihood method. Results: The study subjects comprised 14 CHB patients without complications and 12 CHB patients with cirrhosis/hepatoma. CHB patients with cirrhosis/hepatoma were older than those without complications. The HBV genotypes comprised 15 (57.7%) genotype C and 11 (42.3%) genotype B. All treatment-naïve CHB patients did not demonstrate any classical NA resistance mutations within the RT gene. However, several putative and pretreatment resistance mutations, including F221Y, N238H, and V224I, were high frequency in more than 40% of study subjects. In addition, F221Y and N238H/Q mutations were frequently observed in genotype B, while V224 I was only found in patients infected with genotype C (p=0.000). Conclusions: There was no evidence of classical RT gene mutations associated with NA resistance in treatment-naïve patients with CHB. However, several putative and pretreatment mutations were identified as genotype-specific mutations and may contribute to antiviral resistance against NAs.
Co-Authors Abdur Rahman Hamid Adinda, Irviana Tri Adli, Muhammad Faiz Aleem, Zellina Shaqueela Arfianti Arfianti Ari Alvaren Asputra, Hendra Dedi Affandi Desvira, Melinda Dita Kartika Sari Fauzia Andrini Filza Rifqi Aufa Aslam Guntur Surya Alam Heru Ardila Putra Huriatul Masdar Indarwati, Citra Lestari Indra Jaya Indrajaya Ismar Ibrahim Ismar Ismar Khaifah, Noor Zakiyah Laode Burhanuddin Laode Burhanuddin Mursa Lofina Mutia Dewi Maisaroh Maisaroh Mitra Mitra Nabila, Nabila Putri Sari Putri, Reta Amelia Rabiatul Adawiyah Ramadhanti, Annisa Salsabila Rohadi Rohadi Salamullah Sari, Dita Kartika Soripada, Timotius Agung Syahputra, Febrian Valentino, Andrea Vidi, Darrel Vania Putri Wahyu Jati Wibowo Wendy Desrullah Prada Widya Cahya Purnama Wiwit Ade Fidiawati Yolla Fitri Elmi Yuliaji Narendra Putra Zainal Abidin