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All Journal Indonesian Journal of Medicine Journal of Health Policy and Management
Ambarsari, Anggraini
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Medicine & Pharmacology Public Health

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The Effectiveness of Health Management-Assisted Technology on Glycated Hemoglobin Levels in Patients with Type 2 Diabetes Mellitus: Meta-Analysis Novianto, Fajar; Amalin, Atika Mima; Handayani, Anggun Fitri; Ambarsari, Anggraini; Ode, Diana; Azizah, Alfi Makrifatul; Pamilih, Ayu Trisni; Damalita, Annisa Fitriana; Firda, Fathiyyatu Assa'diy; Mubarok, Ahmad Syauqi
Journal of Health Policy and Management Vol. 6 No. 2 (2021)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Given the number of patients failing to achieve control of Diabetes Mellitus (DM), it causes an increase in the incidence of DM complications. Along with the rapid deve­lopment of technology in this era, this study aimed to prove the effectiveness of technology-based health management compared to usual treatment for levels glycated hemoglobin (HbA1c) in type 2 diabetes mellitus patients.Subjects and Method: This was a meta-ana­lysis using a randomized controlled trial. Arti­cles were obtained from PubMed, Google Scholar, and ResearchGate databases. The arti­cles used in this study were those published from 2012-2021. The search article was carried out by considering the eligibility of the criteria determined using the PICO model. Population: type 2 DM patients (HbA1c>7%), Intervention: health management-assisted technology, Com­parison: usual care Outcome: HbA1c levels. There were 10 articles used with a sample size of 1693 people who were divided into two groups (845 people in the health management-assisted technology group and 848 people in the group usual care). Articles were analyzed using Review Manager 5.3 Appli­cation to determine the Standard Mean Diffe­rence (SMD) and heterogeneity of the study sample.Results: From 10 articles that were processed using RevMan 5.3, significant results were obtained, this is indicated by the overall effect (diamond) which does not touch the vertical line H0 (d= 0) and can also be seen from the 95% CI range of -0.62 to -0.13 which shows significant because it does not pass the number 0 (SMD= -0.37; 95% CI= -0.62 to -0.13; p= 0.003). The heterogeneity of the research data shows I2 = 82% so that the distribution of the data is very heterogeneous (random effects model).Conclusion: Using technology to help health management of patients with type 2 diabetes mellitus can reduce HbA1c levels compared to usual care.Keywords: Health management, technology, diabetes mellitus, HbA1cCorrespondence: Fajar Novianto. Center for Research and Deve­lopment of Medicinal Plants and Traditional Medicine, National Institute of Health of Health, Jl. Raya Lawu No. 11 Karanganyar, Central Java. Email: dr.fajarnovianto@gmail.­com.Journal of Health Policy and Management (2021), 06(02): 81-93https://doi.org/10.26911/thejhpm.2021.06.02.01 
Probiotics and Its Effects on the Cognitive Development in Children: A Meta-Analysis Ambarsari, Anggraini; Murti, Bhisma; Rahardjo, Setyo Sri
Indonesian Journal of Medicine Vol. 7 No. 2 (2022)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

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Background: Due to its high morbidity and mortality rate, diarrhea is still a major health problem among children, particularly toddlers, in developing countries. One of the causes of diarrhea in children is the side effect of antibiotics or known as antibiotic-associated diarrhea (AAD). Evidences of studies conducted in several countries indicated the high use of antibiotics among children that put the group at a high risk of enduring AAD. Probiotics has shown efficacy in preventing and curing various medical conditions, especially those involving digestive tract in children.Subject and Method: It was a systematic review and meta- analisis study. Data collection was conducted by obtaining from databases, namely: Google Scholar, PubMed, Scopus and Science Direct. The study was analyzed by using RevMan 5.3 software. Inclusion criteria used were full paper in English with Randomized controlled trial design during the period of 2000-2022. Keywords used were “Probiotic” AND “Antibiotic Associated Antibiotic” AND “Child” AND “Randomized Controlled Trial”.Results: Meta-analisis was conducted to 9 primary studies from several countries such as Poland, Italy, Korea, Iran, and Australia. Mata-analysis concludes that there were effects of probiotics toward antibiotic-associated diarrhea. Children who were given probiotics had one-third time risk of diarrhea episodes compared to those who were not given probiotics (RR= 0.32; 95% CI= 0.23 to 0.44; p<0.001). Heterogeneity of between-study effect estimates of the meta-analysis data was (I2= 0%; p= 0.096) therefore, calculation of effect estimates was written by using fixed effect approach. Funnel plot did not identify the occurrence of publication bias out of the meta-analysis. Therefore, the funnel plot did not identify the occurrence of publication bias.Conclusion: Probiotics have effects in reducing antibiotics-associated diarrhea incidences in children.Keywords: probiotics, diarrhea, antibiotics.Correspondence:Anggraini Ambarsari. Masters Program in Public Health, Sebelas Maret University. Jalan Ir. Sutami 36A, Surakarta 57126, Jawa Tengah, Indonesia. Email: Aanggraini.ambarsari29@gmail.com. Mobile: 085600184363Indonesian Journal of Medicine (2022), 07(02): 232-241https://doi.org/10.26911/theijmed.2022.07.02.11
Co-Authors Atika Mima Amalin Azizah, Alfi Makrifatul Bhisma Murti Damalita, Annisa Fitriana Firda, Fathiyyatu Assa'diy Handayani, Anggun Fitri Mubarok, Ahmad Syauqi Novianto, Fajar Ode, Diana Pamilih, Ayu Trisni Rahardjo, Setyo Sri