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Journal : The Journal of Society Medicine (JSOCMED)

Correlation of Bronchoscopy Visualization With Cell Type in Lung Cancer Patients at Haji Adam Malik Hospital Medan 2023 Fachrina, Intan; Bihar, Syamsul; Syarani, Fajrinur
Journal of Society Medicine Vol. 3 No. 10 (2024): Oktober
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i10.167

Abstract

Introduction: Lung cancer is defined as a tumor that originates in the lung parenchyma or is located around the bronchi. The two main types are Non Small Cell Lung Carcinoma (NSCLC) and Small Cell Lung Carcinoma (SCLC). When carrying out the procedure, several bronchoscopy visualizations are assessed, such as the bronchial lumen, bronchial mucosa, secretions and bronchial anatomy. Timely bronchoscopic intervention is important for rapid and accurate diagnosis. To determine the relationship between bronchoscopic visualization and carcinoma cell type characteristics from histopathology. Method: This study was conducted with an observational analytic design conducted in a cross-sectional manner, from October 2023 to May 2024. The subjects of this study were taken from the population of lung cancer patients who were hospitalized and outpatient in the hospital, were found to be 67 samples of Non Small Cell Lung Carcinoma (NSCLC). Data included bronchoscopic visualization with lung carcinoma cell type from histopathology, were analyzed univariately and bivariately to assess the relationship between bronchoscopy visualization and lung carcinoma cell type. Results: All patients had Non Small Cell Lung Cancer (100%) are Adenocarcinoma as much as 63% and Squamous Cell Carcinoma as much as 37%. Bronchoscopy visualization shows a central location (62%), partially closed lumen (65%), smooth mucosa (64.5%), mucoid secretion (83.8%), and most often in the right main bronchus (32.2%). Conclusion: There was a significant relationship between bronchoscopy location and type of lung cancer cell (P value 0.001), as well as between mucosa and cell type (P value 0.001).
Correlation Between Neutrophil to Lymphocyte Ratio (NLR) and Procalcitonin Levels in Sepsis Pneumonia Patients Purba, Angela Yurika; Bihar, Syamsul; Sinaga, Bintang Y.M.
Journal of Society Medicine Vol. 3 No. 11 (2024): November
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i11.175

Abstract

Introduction: According to the World Health Organization's global health estimates, lower respiratory infections are the fourth leading global cause of deaths and the deadliest communicable disease, causative for three million deaths worldwide in 2016. Despite the introduction of antibiotic therapies in the 1950s, pneumonia mortality has not decreased substantially, and sepsis, septic shock or acute pulmonary failure (eg acute respiratory distress syndrome, ARDS) are frequent secondary complications. To improve management and treatment of pneumonia, supporting microbiological and virological tests from throat swabs, sputum or blood cultures might be indicated to identify the responsible pathogen(s) and to allow targeted antimicrobial or antiviral therapy. To determine the relationship between procalcitonin level and neutrophil to lymphocyte ratio in sepsis pneumonia patients. Method: This study was conducted with an observational analytic design conducted in a cross-sectional manner, from January 2023 to December 2023. The subjects of this study were taken from the population of sepsis pneumonia patients who were hospitalized at intensive care unit, were found to be 132 samples. Data included procalcitonin level and neutrophil to lymphocyte ratio from laboratory findings, were analyzed with univariate and bivariate method to assess the relationship between procalcitonin level and neutrophil to lymphocyte ratio. Results: In this study, white blood cell, neutrophil and neutrophil/lymphocyte ratio values were found to be significantly higher in patients with elevated procalcitonin. Among the 132 samples, the mean of procalcitonin level was between ≥ 2 to 10 (39,39%) and neutrophil to lymphocyte ratio was between ≥ 11 to 17 (50%). Conclusion: There was no significant relationship between procalcitonin level and neutrophil to lymphocyte ratio in sepsis pneumonia patient at intensive care unit in Adam Malik Hospital Medan (P value 0.816).