Article Per Year (5 Year)
p-Index From 2020 - 2025
2.636
P-Index
This Author published in this journals
All Journal Molecular and Cellular Biomedical Sciences (MCBS) Jurnal Respirologi Indonesia Jurnal Respirasi (JR) AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Respiratory Science Jurnal Impresi Indonesia The Journal of Society Medicine (JSOCMED)
Tarigan, Setia Putra
Division Of Thoracic Oncology, Department Of Pulmonology And Respiratory Medicine, Faculty Of Medicine, Universitas Sumatera Utara/Haji Adam Malik General Hospital, Medan, Indonesia.
Religion Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

Published : 15 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 15 Documents
Search

 1   2 
The Characteristics of The General Population in Medan Undergoing Lung Cancer Screening with NARU Febiyanti, Mica; Tarigan, Setia Putra; Soeroso, Noni Novisari; Eyanoer, Putri Chairani
Journal of Society Medicine Vol. 3 No. 10 (2024): Oktober
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47353/jsocmed.v3i10.165

Abstract

Introduction: Indonesia introduced the NARU lung cancer screening form to assess individual risk levels for lung cancer, classifying them as low, medium, or high risk. This study aimed to analyze the characteristics of low, medium and high risk groups in Medan city. Methods: A quantitative, descriptive cross-sectional design was used, involving 100 individuals from primary health care facilities across 11 areas, who were evaluated using the 9-question NARU form. Evaluation concluded the individuals into low, medium, and high risk of lung cancer. Results: The  majority of the responded high-risk group for lung cancer, the majority were males aged 45-65 years. They had no personal or family history of cancer but were active smokers, worked in carcinogenic environments, and did not live in homes or environments with carcinogenic risks. Additionally, they had a history of COPD and/or TB. In the moderate-risk group, both males and females aged 45-65 years were included, with no personal or family cancer history. They were passive smokers, did not work in carcinogenic environments, and did not live in homes or environments with carcinogenic risks. None had a history of COPD or TB. In the low-risk group, the majority were females under 45 years. They had no personal or family cancer history, were non-smokers, did not work in carcinogenic environments, and did not live in homes or environments with carcinogenic risks. They also had no history of COPD or TB. Conclusion: The study concluded that in Medan, 48% of the population fell into the moderate-risk group for lung cancer, while 31% were in the low-risk group, and 21% were classified as high risk.
Thoracic CT Scan Image in Transudate and Exudate Pleural Effusion Cases at Haji Adam Malik General Hospital Medan in January - September 2024 Lokman, Yovita Belva; Putra, Dedy Dwi; Tarigan, Setia Putra; Malisie, Ririe Fachrina
Journal of Society Medicine Vol. 3 No. 12 (2024): December
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v3i12.185

Abstract

Introduction: Pleural effusion is the most common pleural disease, typically diagnosed through thoracentesis. However, thoracentesis carries risks of complications. Chest CT scans offer a non-invasive alternative to assess pleural effusion and distinguish between exudate and transudate types. Methods: This retrospective cross-sectional study was conducted on patients with pleural effusion at Haji Adam Malik General Hospital, Medan. A total of 80 patients were included. Statistical analysis was performed to evaluate the correlation between demographic, clinical, and thoracic CT findings with the type of pleural effusion. The Mann-Whitney test determined the efficacy of attenuation values in differentiating exudate and transudate. Results: Of the 80 patients, 57 (71.3%) had exudative pleural effusion and 23 (28.7%) transudative. The sample comprised 43 males (53.8%) and 37 females (46.3%), with a mean age of 48.44 ± 18.532 years (range: 2–84 years). Significant correlations were found between the etiology of pleural effusion and pleural nodules with effusion type (p = 0.000 and p = 0.023, respectively). No significant correlations were observed between age, gender, or other CT findings with effusion type (p > 0.05). Attenuation values on CT scans effectively distinguished exudative from transudative effusion (p = 0.000). A cutoff attenuation value of 17.5 Hounsfield Units (HU) demonstrated an AUC of 0.887, with 84.2% sensitivity and 82.6% specificity. Conclusions: Thoracic CT scans are effective for differentiating exudative and transudative pleural effusion. Significant differences were identified in etiology, pleural nodules, and attenuation values, supporting the use of CT imaging as a non-invasive diagnostic method
Effectiveness of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor (TKI) on Life Expectancy in Non-Small Cell Lung Cancer Patients in Medan City Harahap, Putri Wulandari; Tarigan, Setia Putra; Soeroso, Noni Novisari; Ashar, Taufik
Journal of Society Medicine Vol. 4 No. 2 (2025): February
Publisher : CoinReads Media Prima

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71197/jsocmed.v4i2.193

Abstract

Introduction: Non-small cell lung cancer (NSCLC) is strongly linked to epidermal growth factor receptor (EGFR) mutations, with tyrosine kinase inhibitors (TKIs) serving as a primary treatment. While TKIs demonstrate substantial antitumor effects, resistance differs across generations. This study evaluates the impact of first- and second-generation EGFR TKIs on the survival outcomes of NSCLC patients in Medan. Method: A retrospective cross-sectional study was conducted on 67 EGFR-positive NSCLC patients treated with TKIs between 2017 and 2022. Medical records from four hospitals-Haji Adam Malik Hospital, Elisabeth Hospital, Prof. Dr. Chairuddin Panusunan Lubis USU Hospital, and Pirngadi Hospital-were analyzed. Patients aged >18 years with EGFR mutations (exon 18, 19, or 21) and complete records were included. Survival outcomes, including Progression-Free Survival (PFS), Median Survival Time (MST), and Overall Survival (OS), were compared using the Mann-Whitney test. Results: All 67 patients received either first- or second-generation TKIs. Statistical analysis revealed that patients treated with second-generation TKIs had significantly better PFS, MST, and OS than those receiving first-generation TKIs (p < 0.05). Conclusion: This retrospective study faced limitations due to incomplete data and did not assess adverse effects. However, findings indicate that second-generation EGFR TKIs provide superior survival benefits for NSCLC patients compared to first-generation TKIs. Further prospective studies are needed to validate these results and explore the impact of treatment-related toxicity.
Characteristic of Adenocarcinoma Lung Patients With Ros-1 Mutation Among North Sumatra Population Ritonga, Adewita; Soeroso, Noni Novisari; Tarigan, Setia Putra
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Volume 11 No.1 Mei 2025
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Lung cancer is expected to be the most frequent cancer by 2020, accounting for over 2 million diagnoses and approximately 1.8 million deaths globally. Lung cancer, the most prevalent cancer, is identified by histopathological characteristics such as ROS-1 mutations, which impact 0.9% to 2.6% of adenocarcinomas worldwide with no data from Indonesia. The aim of this study is to examine the clinical characteristics of patients with ROS-1-mutant adenocarcinomas. A study with a cross-sectional design. Clinical characteristics of patients include their gender, history of smoking, family history of cancer, clinical stage, and the histological grading of their adenocarcinoma in hospitals. ROS-1 using RT-PCR in conjunction with paraffin blocks. A total of 90 adenocarcinoma patients were included in the study. The majority of patients were male (66.7%), aged 41–60 years (55.6%), former smokers (67.8%), and had no family history of cancer (97.8%). The highest malignancy level was at stage IVA (82.2%), with poorly differentiated histopathological grading being the most common (53.3%). The detection of ROS-1 fusion in 2% of patients emphasizes the need for molecular analysis in assessing individual genetic risk. ROS-1 fusion detection was obtained in 2% of female patients who were younger (average age 50 years) and never smoked. Only 2% of patients in the North Sumatra region met the criteria for ROS-1 fusion, including being female, being younger than the average patient age of 50, and not smoking.
Correlation Between Fagerstrom Score and Brinkman Index With Spirometry Results in Lung Cancer Patients at Haji Adam Malik General Hospital and Prof. Dr. Chairuddin Panusunan Lubis Hospital University of North Sumatera Medan Pinem, Agung Haganta; Tarigan, Setia Putra; Tarigan, Amira P.; Ashar, Taufik
Jurnal Impresi Indonesia Vol. 4 No. 8 (2025): Indonesian Impression Journal (JII)
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/jii.v4i8.6944

Abstract

Lung cancer is one of the leading causes of cancer-related deaths globally. Cigarette smoking remains the primary risk factor. The Fagerstrom Test for Nicotine Dependence (FTND) and the Brinkman Index are used to assess nicotine addiction and smoking intensity, respectively. These indices are associated with pulmonary function, typically assessed through spirometry. Objective: To determine the relationship between Fagerstrom scores and Brinkman Index with spirometry results in lung cancer patients. Methods: This quantitative observational study applied a cross-sectional design involving 68 smoking lung cancer patients at RSUP Haji Adam Malik and RS Prof. CPL Universitas Sumatera Utara. Data were collected via FTND and Brinkman Index questionnaires and spirometry testing. Data were analyzed using the Kruskal-Wallis test with a significance level of p<0.05. Results: Most patients exhibited moderate nicotine dependence (44.1%) and moderate smoking history per Brinkman Index (52.9%). Spirometry results indicated a high prevalence of obstructive and restrictive impairments. There was a significant correlation between FTND/Brinkman Index and lung function (p<0.001). Conclusion: Both Fagerstrom scores and Brinkman Index show a strong relationship with spirometry outcomes, indicating impaired pulmonary function among lung cancer patients.
Co-Authors Arieta, Lydia Azizah Ghanie Icksan Darren Wan-Teck Lim Dedy Dwi Putra, Dedy Dwi Elizabeth Napitupulu Erna Mutiara Erna Mutiara Erna Mutiara Febiyanti, Mica Fotarisman Zalukhu Harahap, Putri Wulandari Hendra Taufik Hidayat Hidayat Lokman, Yovita Belva Lucia Aktalina Malisie, Ririe Fachrina Muhammad Harbi Praditya Muhammad Harbi Praditya Muntasir Abdullah Netty Delvrita Lubis Noni Novisari Soeroso Noni Novisari Soeroso Noni Novisari Soeroso Noni Novisari Soeroso Noni Novisari Soeroso Novia Nurul Faizah Novita Margaretta Ambarita Nurul Ramadhani Pinem, Agung Haganta Putri Chairani Eyanoer, Putri Chairani R.A Henny Anggriani Ritonga, Adewita Rosidah Hanum Hasibuan Rosita Juwita Sembiring Stephen Johan Prasetyo Tarigan, Amira P. Taufik Ashar Wan Betty Pratiwi Yahwardiah Siregar