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Journal : Veterinary Biomedical and Clinical Journal

The Effect of Triponyl Sulphate on Fetuses Development and Placental Abnormalities in Inducing Preeclampsia of Rattus norvegicus animal model Purwatiningsih, Wawid; Aryani, Dhita Evi; Vidiastuti, Dian; Oktanella, Yudit; Firmawati, Aulia
Veterinary Biomedical and Clinical Journal Vol. 1 No. 1 (2019)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (672.49 KB) | DOI: 10.21776/ub.VetBioClinJ.2019.001.01.6

Abstract

Preeclampsia is one of the obstetrical problems that can cause maternal and fetal morbidity and mortality. Preeclampsia causes the fetus born prematurely and low fetal weight. This is caused by high blood pressure which causes decrease of blood delivery to the placenta, so the supply of oxygen and food to the fetus decreases. As a result, fetal development inhibits and trigger born prematurely. More fatal, this disease cause the release of placental tissue from the uterus prematurely. The aim of this study was to determine the effect of administration of triponyl sulfate as induction of increased blood pressure in preeclampsia animal models, fetal development with alizarin red staining and placental abnormalities. The experimental animals were rats Rattus norvegicus mated with male rats monomating , 4 months old and 250-300 grams body weigh. Pregnant female rats were induced by triponyl sulfate 70 mg / kg BW (k +) and without induced by triponyl sulfate (k-). The results of the study showed that there were formation of the sternal bone in k- and malformation of the sternum bone at k +. Placental abnormalities occured in k +, it could be seen in the presence of ghos villi in blood vessel abnormalities in the preeclampsia placenta caused by there was no invation of trophoblast cells in the whole or partial spiral arteries and the mean of blood pressure increased.
The Knowledge Enhancement of Al Huda MTS Students about The Use, Storage and Disposal of Animal Medicine through Educational Seminars and Demonstration Aryani, Dhita Evi; Herawati, Herawati; Oktavianie, Dyah Ayu; Permata, Fajar Shodiq
Veterinary Biomedical and Clinical Journal Vol. 2 No. 2 (2020)
Publisher : Faculty of Veterinary Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.VetBioClinJ.2020.002.02.1

Abstract

Currently, there are many pet shops, animal clinics, and animal lover communities in Malang. Data from UB's animal education hospitals showed an increasing number of patients visiting there. This reflects that the owner had considered his favorite animal as part of his family that must be treated if they are sick. Drugs medicine plays an important role in the treatment of animal diseases. Therefore, pet owners must know how to use and store drugs properly so that the efficacy of the drug does not change, and the results of treatment are achieved. When the drug is not used anymore, the owner must know how to properly dispose of the drug to prevent the drug from being mixed, polluting the environment, or even being used by irresponsible people. The aim of this community service was to provide additional knowledge about how to use, store and dispose of veterinary medicines. The theme we took was "Increasing Knowledge of Al-Huda MTS Students on the Use, Storage and Disposal of Animal Medicine through Educational Seminars and Demonstration". Community service methods used were counseling and seminars on the use, storage and disposal of veterinary medicines and demonstrations on how to give medicines to cats. The evaluation tools used were pretest and posttest. The pretest and posttest results showed an increase in the knowledge of MTS Al-Huda students about how to give medicines to pets - especially cats -, how to store and dispose of drugs that are not used. While the results of the questionnaire showed a very good response related to community service.