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Husnayanti, Ana
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Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences

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Journal : Pharmacy Reports

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Aromatherapy candle formulation from Citrus microcarpa peel Meryta; Husnayanti, Ana; Sinulingga, Syamsul Rizal; Sudirman, Muhammad Seto
Pharmacy Reports Vol. 2 No. 2 (2022): Pharmacy Reports
Publisher : Indonesian Young Scientist Group and UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51511/pr.49

Abstract

Candles can serve a dual purpose of not only providing light but also acting as a means of aromatherapy. Aromatherapy, which involves the use of essential oils, such as calamansi peel (Citrus x microcarpa Bunge), is an alternative form of treatment. The objective of this study was to determine the optimal concentration of essential oil, evaluate the characteristics of aromatherapy candles, and assess their appeal. The pre-experimental technique employed a one-time case study/post-test design, with soy wax used as the candle's wax base. The preference test for aromatherapy candles involved 30 untrained individuals. The candles exhibited a uniform color, with no cracks, defects, fractures, or air bubbles. The candle with a 3% formulation demonstrated the longest burning time and quickest melting point. Furthermore, candles containing 3% essential oil were preferred both before and during burning. Additionally, this formulation displayed the fragrance promptly, with the quickest perceived effect time.
Characteristic and taste test of aromatherapy candle from essential oil of Cananga odorata Kumalasari, Desy; Husnayanti, Ana; Pratiwi, Auronita Puspa
Pharmacy Reports Vol. 3 No. 2 (2023): Pharmacy Reports
Publisher : Indonesian Young Scientist Group and UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51511/pr.52

Abstract

Kenanga or ylang-ylang (Cananga odorata) is renowned in the pharmaceutical domain for its essential oil, which boasts therapeutic properties. This study aims to investigate the feasibility of utilizing C. odorata essential oil in the production of aromatherapy candles. It focuses on examining the oil’s characteristics, candle properties, and consumer preferences. The oil extraction employed the enfleurage method, while purification was achieved using a rotary evaporator. We adhered to the SNI 06-3949-1995 standards for analyzing the essential oil and the resultant candle characteristics. Consumer preferences were evaluated through surveys conducted with 30 panelists. The study’s results revealed an oil yield of 48.5%, consistent with the established standards. Optimally, the formula with 25% essential oil concentration demonstrated superior performance in aromatherapy candles, exhibiting a burn time of 8 hours, 30 minutes, and 30 seconds, and a melting point ranging from 51°C to 53°C. This concentration also elicited positive responses from participants in terms of the candles' appearance, aroma (both before and after burning), and therapeutic impact. Notably, the candles with a 25% essential oil concentration were most effective in rapidly delivering therapeutic benefits, predominantly inducing relaxation. The study concludes that ylang-ylang essential oil is highly promising for aromatherapy candle production, with the 25% concentration formula demonstrating optimal results in terms of standard compliance, burn time, and user satisfaction.
Dermatological properties of Cosmos caudatus Kunth for photoprotection, anti-aging, and skin brightening applications Husnayanti, Ana; Sugiyanto; Kintoko; Nurhayati
Pharmacy Reports Vol. 5 No. 2 (2025): Pharmacy Reports
Publisher : Indonesian Young Scientist Group and UPN Veteran Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51511/pr.114

Abstract

Cosmos caudatus Kunth, a tropical medicinal herb traditionally used across Southeast Asia, has emerged as a promising botanical ingredient for cosmeceutical applications. This narrative review systematically synthesizes current evidence on its dermatological properties through comprehensive literature search of Scopus and PubMed databases (2015-2025), yielding 25 studies meeting inclusion criteria for skin-relevant bioactivities. Phytochemical characterization consistently identifies flavonoid glycosides, particularly quercetin derivatives (quercitrin, isoquercitrin, rutin), as major bioactive constituents responsible for multifaceted skin benefits. In vitro studies demonstrate potent antioxidant activity (IC₅₀ 17.77-163.6 μg/mL in DPPH assay), significant inhibition of collagenase, elastase, and matrix metalloproteinases underlying anti-aging effects, and superior tyrosinase inhibition (IC₅₀ 6.803 μg/mL) for skin brightening. Photoprotective capacity exhibits remarkable formulation-dependent enhancement, progressing from minimal protection in raw extracts (SPF 3.26) to ultra-protection in optimized cream formulations (SPF 45.59). Advanced delivery systems including nanotechnology (particle size 160-176 nm) and microencapsulation (79.67% flavonoid retention) further enhance stability and bioavailability. Additional antimicrobial activity against Propionibacterium acnes positions C. caudatus uniquely for acne-hyperpigmentation management. Despite robust in vitro evidence, clinical validation through human trials remains a critical research priority. This review establishes C. caudatus as a scientifically validated, multifunctional botanical ingredient with substantial commercial potential in the natural cosmeceutical market.
Co-Authors chaerani, erni Febriansyah, Ricky Harindra Kintoko Kumalasari, Desy Meryta Nurhayati Oktavia, Liana Devi Pratiwi, Auronita Puspa Siburian, Christine Handayani Sinulingga, Syamsul Rizal Sudirman, M. Seto Sudirman, Muhammad Seto SUGIYANTO Tajudin Tajudin