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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Administrasi Kesehatan Indonesia Jurnal Pendidikan Ekonomi & Bisnis JURNAL TEKNOLOGI INFORMASI Gemakes: Jurnal Pengabdian Kepada Masyarakat Indonesian Journal of Nursing and Health Sciences (IJNHS) Hang Tuah Medical Journal Jurnal MedScientiae Jurnal Kedokteran Meditek
Santi Anugrahsari
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Journal : Jurnal MedScientiae

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Potensi Tepezza (Teprotumumab) dalam Pengobatan Penyakit Mata Tiroid Aktif (TED) Rukmana, Dewi Samudra Putri Aliffa; Ramzi, Rani Nurmala; Dhuarte, Jevon; Jaya, Fitra; Anugrahsari, Santi
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3010

Abstract

Abstract Active Thyroid Eye Disease (TED) is a medical condition involving swelling of the muscles, tissues, and fats around the eyes. This can lead to serious symptoms including double vision and vision loss. Tepezza (Teprotumumab) is an innovative therapy that inhibits the insulin-like growth factor 1 receptor (IGF-1R) and has been approved for TED treatment. Teprotumumab works by reducing inflammation and TED symptoms. Pharmacokinetic studies indicate that this drug can be effectively administered via intravenous infusion. Various studies have shown that teprotumumab can significantly reduce proptosis, diplopia, and clinical activity of TED. This therapy has proven effective in various patient groups, including those with long-standing TED and those unresponsive to other treatments. Teprotumumab holds a promising breakthrough in TED management, improving the quality of life for individuals affected by this disease. Further studies are needed to fully understand the mechanism and potential of teprotumumab in TED treatment.
Literature Review of the New Role of Atropine Eye Drop on Children's Myopia Progression Tanjung, Melita Novianne; Nikiyuluw, Renna Sara; Sombuk, Berlin Clara Yustinah; Anugrahsari, Santi
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3031

Abstract

Myopia is one of the most common refractive disorders, especially in children. It can increase the risk of degenerative eye diseases. Various studies have been conducted to date to show the potential of variations of atropine in inhibiting the progression of myopia. This scientific article summarizes the various research, mainly related to the effectiveness of atropine on myopia. The research method uses "Literature Review" by searching Pubmed and Google Scholar with the English keywords ((“Myopia” OR “Refractive error”) AND “Children” AND “Atropine” AND “Progression”), 2018 until 2023. The discussion summarizes the role of atropine in myopia and its effectiveness and safety. Future research is expected to explore, more specifically, the role of atropine in inhibiting the progression of Myopia.
Current Management of Fluorometholone Steroids in Pediatric Vernal Conjunctivitis: A Literature Review Fajar, Muhammad Fauzi; Siallagan, Maria; Nabighah, Gladis Salsabila Najla; Wijaya, Pande I Gede Indra; Anugrahsari, Santi
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3079

Abstract

Vernal conjunctivitis is a rare allergic eye disease, usually affecting children in the prepubertal years and can last between 5 to 10 years. Treatment of this condition is often challenging, requiring effective therapies to reduce symptoms. This literature review, conducted between 2015 and 2023, aimed to evaluate the effectiveness of fluorometholone steroid use in the treatment of pediatric vernal conjunctivitis. Recent studies comparing the effectiveness of Fluorometholone 0.1% in the treatment of Vernal Keratoconjunctivitis (VKC) were analyzed. The results showed that Fluorometholone was effective compared to Cyclosporine in reducing VKC symptoms. However, the use of Fluorometholone should be done with caution due to potential side effects such as increased intraocular pressure and risk of infection.Fluorometholone is an effective treatment option for vernal conjunctivitis in children. However, it is important to have close monitoring by an ophthalmologist to avoid serious side effects. With careful monitoring and proper dose adjustment, Fluorometholone can be a safe and effective therapy in managing this condition.  
Pengaruh Pemberian Steroid Topikal Terhadap Tekanan Intra Okular : Sebuah Tinjauan Pustaka Lauw, Jessica Amelia; Muthia, Annisa Sri Rachma; Pangaribuan, Beatric Ruth Fransiska; Anugrahsari, Santi
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3162

Abstract

The use of topical corticosteroids, especially in the periocular area, has been associated with increased intraocular pressure (IOP), potentially leading to glaucoma and other eye complications. This study evaluated the risk of IOP elevation due to topical corticosteroid use and its influencing factors. This study is a literature review investigating the relationship between topical corticosteroid use and IOP elevation. Data were collected from studies reporting the effect of topical corticosteroids on IOP, including the type of steroid, duration of use, frequency of administration, and patient age. The findings suggest that the use of topical corticosteroids can lead to a significant increase in IOP, with the risk varying depending on the type of steroid, duration, and frequency of use, as well as individual patient characteristics such as age. Although some studies showed a significant increase in risk, other results showed minimal risk, suggesting the need for close monitoring of IOP in patients using topical corticosteroids. The use of topical corticosteroids in the periocular area requires careful consideration of the potential risk of increased IOP. It is important to choose steroids with low anti-inflammatory potential and monitor IOP regularly to reduce the risk of IOP-related side effects. Further studies are needed to fully understand the risks associated with using periocular topical corticosteroids and develop guidelines for safe use.
Tinjauan Pustaka Penggunaan Gawai dengan Kejadian Miopia Anugrahsari, Santi; Nugraha, Abraham William; Septrilla, Gladys; Veronica Agrippina
Jurnal MedScientiae Vol. 3 No. 1 (2024): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i1.3164

Abstract

Lifestyle changes during the pandemic has impacted the lives of almost every human being in the world. This lifestyle changes, especially the increase in the duration and frequency of gadget use for everyday routine can cause various unwanted side effects such as refractive disorders, especially myopia. This study aims to evaluate the correlation between gadget use and myopia and other relevant ocular biometric parameters such as axial length (AL) and spherical equivalent (SE). The literatures used in this study is taken from an electronic database using NCBI, ProQuest and Google Scholar with English keywords “Gadget”, “Myopia”, and “Vision Impairment” and in Indonesian “Gawai”, “Miopi”, dan “Kelainan Refraksi ”. The articles found was published between January 2012 and Juni 2022, which was then sorted according to the objective of this study and we found fifteen journals that we include in this study. The distance in which gadgets were used was found to have a correlation with myopia. Laying down while using gadgets was also found to be correlated with myopia. Meanwhile, the duration of gadget use has not been found to be correlated with myopia. Gadget use can be one of the risk factors for refractive disorders. Based on the literature we collected, it was found that gadget use distance less than 30 cm and laying down while using gadgets has a correlation with refractive disorders meanwhile the duration of gadget use was found to not be correlated with refractive disorders.
Effectiveness of Prednisolone Acetate Eye Drops 1% in Improving the Final Vision of Anterior Uveitis Patients Anugrahsari, Santi; Celine, Callysta; Saragih, Putri Arsya; Arsana, Gabriel Ferdinan
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3206

Abstract

Anterior uveitis is the most common classification of uveitis and can result in decreased vision, even blindness in sufferers. Therefore, this literature review was carried out to determine the effectiveness of topical steroids, namely prednisolone acetate 1%, in improving final vision in anterior uveitis patients. In this literature review, 6 articles were found from electronic databases in PubMed and Google Scholar, which were selected based on the specified inclusion and exclusion criteria. The study's results stated that prednisolone acetate 1% eye drops effectively improved final vision in anterior uveitis patients. Further research regarding the effectiveness of prednisolone acetate 1% needs to be carried out in a broader scope, with various patient characteristics, to make the research results more accurate.
The use of corticosteroid eye drops in patients post cataract surgey Ana Claudia; Rusanti, Putri Alivia; Sipangkar, Agnes Imelda; Anugrahsari, Santi
Jurnal MedScientiae Vol. 3 No. 2 (2024): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i2.3279

Abstract

The use of corticosteroid eye drops is one of the post-cataract surgery treatments aimed at reducing inflammation and preventing complications. This literature aims to review the effectiveness and safety of topical corticosteroid use in patients after cataract surgery. Reviewing several recent studies on this topic, this literature finds that topical corticosteroids effectively reduce inflammation and speed up post-operative healing. However, there are risks of side effects, such as increased intraocular pressure (IOP), that need to be considered. The literature also discusses comparisons between corticosteroids and non-steroidal anti-inflammatory drugs (NSAIDs), showing that while NSAIDs are also effective, corticosteroids provide better results in controlling inflammation. In conclusion, corticosteroid eye drops are recommended as the standard treatment after cataract surgery with close monitoring of IOP.
Hubungan Antara Screen Time dengan Angka Kejadian Miopia Pada Anak Sebelum dan Setelah Masa Pandemi Covid-19 : Sebuah Tinjauan Pustaka Anugrahsari, Santi; Shania Audrianisa; Cahya Virgin Septyany; Appy, Enjeline Grecielya; Rohy, Charlos Ivanly Jusuf
Jurnal MedScientiae Vol. 3 No. 3 (2024): Desember
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3047

Abstract

The COVID-19 pandemic policies, outdoor activity restrictions, and distance learning have significantly impacted the occurrence of myopia in children. These changes are associated with increased screen time, decreased outdoor activities, and insufficient sleep duration, indicating potential long-term effects on myopia prevalence and development. This literature review utilizes articles from research journal databases searched through the internet. The internet databases used include Google Scholar and PubMed, using keywords: "Children," "Epidemiology," "Risk Factor," and "Myopia." Inclusion criteria for this literature are English articles, published within the last 10 years, and research publication types. Exclusion criteria include duplications and articles with only abstracts or without full text. The combined findings of these studies consistently demonstrate that school-age myopia is influenced by genetic and environmental factors, with screen time, near work, and urban residence being significant risk factors. The protective role of outdoor activities against myopia is evident in various geographic regions. The COVID-19 pandemic has exacerbated this issue, emphasizing the need for interventions focused on reducing screen time and increasing outdoor activities to manage and prevent myopia progression.
Trabekuloplasti pada Glaukoma: Sebuah Tinjauan Pustaka Terkini Lily, Lia Listya; Kalangi, Geraldi Marcelino; Manufandu, Gracea Sintike; Anugrahsari, Santi
Jurnal MedScientiae Vol. 3 No. 3 (2024): Desember
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/JMedScientiae.v3i3.3360

Abstract

Glaucoma is a progressive optic neuropathy that can lead to irreversible blindness, where intraocular pressure (IOP) serves as the only modifiable risk factor for disease control. Among the various treatment modalities, laser trabeculoplasty, especially Selective Laser Trabeculoplasty (SLT), has gained popularity as it improves aqueous humor outflow and reduces IOP. This review combines recent studies comparing SLT with other modalities such as Micropulse Laser Trabeculoplasty (MLT) and their clinical outcomes. The purpose of thisliterature review is to highlight the efficacy of Selective Laser Trabeculoplasty (SLT) in managing intraocular pressure (IOP)in glaucoma patients, especially primary open angle glaucoma (POAG), both as first-line therapy and as adjunctive therapy. Literature sources were selected through an internet search using articles in research journal databases on Google Scholar and Pubmed and 30 literatures were selected from these methods. The literature revealed that SLT, as a first-line therapy or adjunct to medical treatment, effectively lowers IOP and can be repeated safely with continued efficacy. In addition, SLT offers an alternative for patients who are unresponsive to topical treatment, providing a non-invasive optionthat may eliminate the need for surgery. This review also examines the role of SLT in long-term glaucoma management, its comparison with newer techniques, and the effectiveness of repeated treatments in maintaining IOP control. Further studies are recommended to validate the long-term outcomes of SLT, especially for various applications and its comparison with newer laser therapies.
Kontribusi Artificial Intelligent dalam Diagnostik dan Manajemen Penyakit Mata Anugrahsari, Santi; Umboh, Teresa Gracia; Tjandra, Aldo Elyada
Jurnal MedScientiae Vol. 4 No. 1 (2025): April
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i1.3557

Abstract

Artificial intelligence (AI) has come a long way since its introduction in the 1950s. In the past few decades, especially with the advent of machine learning (ML) and deep learning (DL), AI has been able to analyze complex data, learn independently, and have made a major impact on the medical field. Ophthalmology has been one of the major beneficiaries of this technology, thanks to its integration with digital techniques such as Optical Coherence Tomography (OCT), fundus photography, and visual field testing. This study was conducted through a comprehensive literature review using major databases, such as PubMed, Scopus, and Google Scholar. Inclusion criteria included publications in the last five years that were relevant to innovations in AI-based diagnostics and management of eye diseases. A total of 25 journals were selected for analysis, providing insight into the current trends in AI applications for ophthalmology. We found that AI has provided efficiencies in the diagnosis, treatment, and management of eye diseases, as well as expanded access to healthcare through telemedicine. However, challenges such as data validation and algorithm standardization require attention. Through cross-disciplinary collaboration and further development, AI has the potential to revolutionize ophthalmology services to be more inclusive and affordable.
Co-Authors ADHE WILLIAM FANGGIDAE Adrian, Verry Ana Claudia Andarusito, Nurcahyo Andri Lesmana Anindita, Petra Damiana Appy, Enjeline Grecielya Arsana, Gabriel Ferdinan Benu, Inne Eunike Br Tobing, Naomi Regina P Cahya Virgin Septyany Celine, Callysta Desra, Safira Cantika Dhuarte, Jevon Fajar, Muhammad Fauzi Fitra Jaya Fransiskus Sawan Hendarto, Dino Jak, Yanuar Kainama, Chrisella Michelle Kalangi, Geraldi Marcelino Koloay, Gisselle Angeli Marchella Korwa, Daniela Dirgantari Kumala Sari, Ni Putu Winda Kusumaningrum, Dietha Lallo, Ary Kristanto Lauw, Jessica Amelia Lethulur, Shindie Dona Kezia Lily, Lia Listya M, Gabriel Manufandu, Gracea Sintike MAWAR Muthia, Annisa Sri Rachma MUTIARA NOVARINDA ISKAYATI PUTRI Nabighah, Gladis Salsabila Najla Nikiyuluw, Renna Sara Nugraha, Abraham William Pangaribuan, Beatric Ruth Fransiska Prakarsi, Griyanti Purna Ragustri, Jasmine Nazer Ramzi, Rani Nurmala Ratna, Setyarini Dwi Rohy, Charlos Ivanly Jusuf Rukmana, Dewi Samudra Putri Aliffa Rusanti, Putri Alivia Saragih, Putri Arsya Septrilla, Gladys Shania Audrianisa Shendy , Shendy Siallagan, Maria Siceria, Putri Denova Sipangkar, Agnes Imelda Sombuk, Berlin Clara Yustinah Sopian, Silvester Rionoviyanus Temiang Sumidjatun, Sumidjatun Suryadi Tanjung, Melita Novianne TASYA NADHIRATUL HUSNA Teterissa, Shirley Eleonora Gusmariny THOMAS AQUINAS MICHI ALVIYANTO TIARA AGUSTINA Tjandra, Aldo Elyada Umboh, Teresa Gracia Veronica Agrippina Wijaya, Pande I Gede Indra Yulianti, Elys