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All Journal Global Health Management Journal Manuju : Malahayati Nursing Journal Tunas Medika Jurnal Kedokteran & Kesehatan
Herdwiyanti, Menik
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Nursing Public Health

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Journal : Global Health Management Journal

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Comparing Chest Radiograph Lesion Areas in Pulmonary Tuberculosis Patients with and without Diabetes Mellitus: A 2023 Study at Waled Hospital, Cirebon, Indonesia Fatihah, Hapsari Bunga; Latief, Muhammad Amar; Herdwiyanti, Menik
GHMJ (Global Health Management Journal) Vol. 8 No. 2 (2025)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-821161

Abstract

Background: The Global Tuberculosis Report emphasizes a significant number of TB cases, and Indonesia is the second country in Southeast Asia with the most TB cases. Prevalence of TB increases along with the increase of Diabetes Mellitus (DM) prevalence, which both are known to have a negative impact on each other. Clinical symptoms in TB with DM differ from those in TB without DM. However, whether there is any difference in radiology examinations is unknown. This can be a consideration for determining patient therapy based on differences in the chest radiographs. Aims: To determine the Lesion Area Difference on Chest Radiographs of Pulmonary Tuberculosis Patients with and without Diabetes Mellitus at Waled Hospital in 2023. Methods: There were 96 data points based on the first taken chest radiograph from both inpatient and outpatient data, which were obtained from medical records in 2023 at Waled Hospital, Cirebon. Statistical analysis was performed using the Chi-Squared comparative test in this observational study with a cross-sectional design. Results: There were 69 tuberculosis (TB) patients without diabetes mellitus (DM) and 27 TB patients with DM. Overall, patients had minimal lesions (14.6%), moderate lesions (26.0%), and far-advanced lesions (59.4%). The Chi-Square analysis from these samples showed a p-value of 0.870. Conclusion: There is no difference in lesion area on chest x-rays in pulmonary tuberculosis patients with or without diabetes mellitus. Further research is expected to include the type of TB and history of treatment for either TB or DM.
Correlation between Duration of Antiretroviral Therapy and Glomerular Filtration Rate in People Living with HIV/AIDS: A Cross-sectional Study in Cirebon, West Java, Indonesia Ayudhipasha, Tiara Sekar; Herdwiyanti, Menik; Sedayu, Sedayu
GHMJ (Global Health Management Journal) Vol. 8 No. 1s (2025): Special Issues
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-81s1182

Abstract

Background: West Java ranks the highest Province with Human Immunodeficiency Virus (HIV) case in 2023. An estimated 1.648 patients estimated receive antiretroviral therapy (ART). Kidney disease contributes mortality amongst people living with HIV/AIDS (PLWH). Tenofovir disoproxil fumarate (TDF)-based ART was associated as risk factor of kidney disorders, indicate by declining glomerular filtration rate (GFR). However, there is limited study whether kidney disease among PLWH were related to ART use in Indonesia. Aims: To determine correlation between duration of antiretroviral therapy and glomerular filtration rate (GFR) in people living with HIV/AIDS. Methods: This is an observational study with cross-sectional design. Eighty-nine HIV patients on antiretroviral therapy for at least three months with normal baseline GFR were studied. Estimated GFR calculated using the Cockcroft-Gault equation. Data obtained were analyzed with spearman correlation test. Results: Among 89 subjects, as many as 38 patients (42.7%) on therapy less than 12 months, 29 patients (32.6%) were on ART more than 24 months, and 22 patients (24.7%) 12-24 months. ART with normal kidney function were 62 patients (69.7%). Whereas 29.2% were mildly decrease GFR, and only 1.1% were mild to moderate decrease GFR. The analytical statistic showed a no significant between duration of antiretroviral therapy and GFR in PLWH with a p-value of 0.199 and Spearman’s r of 0.137. Conclusion: There was no significant correlation between duration of antiretroviral therapy and glomerular filtration rate in PLWH.
Glycated Hemoglobin Level and Body Mass Index Correlation with Peripheral Artery Disease in Patients with Type 2 Diabetes Mellitus at Waled Hospital, Cirebon, Indonesia Auliya, Tania; Amaliyah, Nihayatul; Herdwiyanti, Menik
GHMJ (Global Health Management Journal) Vol. 7 No. 3s (2024)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-741106

Abstract

Background: Peripheral Artery Disease (PAD) is a condition that reduces blood flow to the lower extremities and is primarily caused by atherosclerosis.  PAD is one of the complications of Diabetes Mellitus (DM). Diabetics have an 11.6 times more likely to develop PAD than those without diabetes. Glycated haemoglobin (HbA1c) levels >7% are at a higher risk of chronic complications. Obesity and overweight also raise the risk of developing PAD disease. However, research on the correlation between Body Mass Index (BMI) and PAD remains unclear and controversial. Aims: To analyze the correlation between HbA1c levels and BMI with the incidence of Peripheral Artery Disease in patients with type 2 Diabetes Mellitus at Waled Hospital.  Methods: This is an analytical observational study with a cross-sectional design. Data was collected on patients diagnosed with type 2 Diabetes Mellitus at the Internal Medicine Clinic at Waled Hospital in June - July 2024. A total sample of 77 was obtained using consecutive sampling. The inclusion criteria were type 2 DM, aged 19-60 years, and medical record data equipped with the HbA1c levels for at least the last 3 months prior to data collection. The exclusion criteria were patients with a history of diabetic ulcers, amputation and limb disability, Acute Coronary Syndrome, stroke, kidney failure, recurrent anaemia, and blood transfusions in the last 3 months. Primary data was gathered through an ABI examination, while secondary data was obtained from medical records. The data was analysed using the Spearman correlation test. Results: Patients had poor HbA1c control (51.9%), moderate HbA1c control (29.9%) and good HbA1c control (18.2%), with the majority of patients had normal BMI (39%) followed by obese I (22.1%), overweight and obese II (16.9%). Our study showed that the distribution of PAD levels was severe (0%), moderate (3.9%), mild (44.2%), normal (46.8%), and arteriosclerotic (5.2%). The correlation test showed p-0.789 (p> 0.05) for HbA1c levels with PAD and p- 0.653 (p>0.05) for BMI with PAD. Conclusion: There was no association between glycated hemoglobin or Body Mass Index values and the incidence of PAD in patients with type 2 Diabetes Mellitus at Waled Hospital, Cirebon, Indonesia. Received: 25 September 2024  |  Reviewed: 21 October 2024  |  Revised: 30 November 2024  |  Accepted: 11 December 2024.
Co-Authors Agustina, Dwi Rosa Eka Albab, Arthur Ulil Amaliyah, Nihayatul Anjani, Faizah Auliya, Tania Ayudhipasha, Tiara Sekar Canceryta, Sherly Fatihah, Hapsari Bunga Ignatius Hapsoro Wirandoko Indriyati, Rose Latief, Muhammad Amar Marfuati, Sri Octavrisa, Friska pamungkas, Nanda dwi Pitaloka, Amalia Dwi Ayu Rahayu, Esa Giri Rama Samara Brajawikalpa Romdhoni, Mohamad Sedayu, Sedayu Silvia, Indriani Widi Astuti