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All Journal Global Health Management Journal PREPOTIF : Jurnal Kesehatan Masyarakat Indonesian Journal of Applied Research (IJAR) JPM: JURNAL PENGABDIAN MASYARAKAT International Journal of Health and Pharmaceutical (IJHP) Jurnal Sehat Indonesia (JUSINDO)
Marfuati, Sri
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Antimicrobial Activity of Ethyl Acetate Fraction of Kersen Leaves Against Staphylococcus aureus and Escherichia coli Weni, Mustika; Marfuati, Sri
Indonesian Journal of Applied Research (IJAR) Vol. 5 No. 3 (2024): Indonesian Journal of Applied Research (IJAR)
Publisher : Universitas Djuanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/ijar.v5i3.531

Abstract

The underutilized leaves of the kersen plant contain secondary metabolite compounds that have antibacterial potential. The aim of this research was to test the antibacterial activity of the ethyl acetate fraction of kersen leaf against Escherichia coli and Staphylococcus aureus and determine the best concentration. Kersen leaf extraction method using the maceration method using ethanol solvent, fractionation method using ethyl acetate solvent and testing the antibacterial activity of kersen leaf against Staphylococcus aureus and Escherichia coli using the well diffusion method. The normality test used was the Shapiro-Wilk test and used the One-way Anova parametric statistical test. The results of the phytochemical screening of kersen leaf contain compounds phenols, saponins, tannins, alkaloids and triterpenoids. Concentration of 20% of the ethyl acetate fraction of kersen leaf can inhibit Escherichia coli by 8,817 mm in the medium category and Staphylococcus aureus by 7,987 mm in the medium category. The inhibitory power of the ethyl acetate fraction is higher in inhibiting Escherichia coli than Staphylococcus aureus.
Dampak Optimalisasi Kesehatan Remaja dengan Edukasi Bijak Dalam Penggunaan Obat Kepada Siswa SMP Marfuati, Sri; Weni, Mustika; Brajawikalpa, Rama Samara; Emallia Fitriani
JPM: Jurnal Pengabdian Masyarakat Vol. 6 No. 1 (2025): Juli 2025
Publisher : Forum Kerjasama Pendidikan Tinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47065/jpm.v6i1.2444

Abstract

Self-medication is increasingly common among the general public, including adolescents. However, a lack of proper understanding regarding drug use, storage, and disposal can lead to medication errors that pose serious health risks. This community service activity aimed to improve the knowledge of students at SMP regarding the proper and responsible use of medications through an educational session titled “Using Medicines Wisely.” The activity was conducted on May 24, 2025, by lecturers from the Faculty of Medicine, Universitas Swadaya Gunung Jati (UGJ), using a face-to-face method involving a pre-test, educational material delivery, interactive discussion, and a post-test. Pre-test results showed that only 22% of participants had good knowledge, which increased to 68% after the educational session with the meaning of value. These findings indicate that the activity effectively enhanced students’ understanding of responsible self-medication practices, particularly in recognizing drug types, usage instructions, proper storage, and safe disposal methods. This program is expected to foster wise medication habits from an early age and contribute to the development of a health-conscious society.
Analgesics Self-Medication Among Community In Cirebon District, Indonesia Marfuati, Sri; Pratiwi, Witri; Khasanah, Uswatun
Jurnal Sehat Indonesia (JUSINDO) Vol. 7 No. 2 (2025): Jurnal Sehat Indonesia (JUSINDO)
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jsi.v7i2.305

Abstract

Background: Self-medication with analgesics may cause inappropriate medication and potentially dangerous side effects. However, data on analgesic self-medication profiles in Cirebon, Indonesia, is still limited. Aims: This research aims to analyze the profile of self-medication with analgesics among the Cirebon District, Indonesia community. Methods An observational study with a cross-sectional approach was conducted in 5 pharmacies in the Cirebon District. The sample in this study was people who bought analgesics without a doctor's prescription at the pharmacy. Primary data were obtained through a questionnaire regarding sociodemographic characteristics, reasons for self-medication, and sources of information in choosing analgesics. Results: 470 respondents participated in this study, consisting of 35.96% male and 64.04% female. The majority of samples were 31-55 years old (54.9%), worked as housewives (36.60%), senior high school graduates (39.15%), married (74.68%), and had low income (60.43%). Only 13.83% of the sample has health insurance (private or national health insurance). Most of the samples performed self-medication with analgesic because they were used to doing it (34.25%). Most of the samples received information about analgesics they consumed from health workers (39.79%). Conclusion: Self-medication with analgesics among community in Cirebon Regency, Indonesia, is mainly carried out by low-income people because they are used to treating themselves. They get information about analgesics purchased from health workers. Prevention needs to be done through promotion and education to the public regarding the side effects of self-medicated analgesics so that they do not use them without consulting a doctor.
Comparison of the Effectiveness of Antihypertensive Drugs Captopril 25 mg and Amlodipine 5 mg in Lowering Blood Pressure in Hypertensive Patients Amal, Ichlasul; Marfuati, Sri; Istisakinah, Rini
International Journal of Health and Pharmaceutical (IJHP) Vol. 5 No. 4 (2025): November 2025
Publisher : CV. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51601/ijhp.v5i4.455

Abstract

Hypertension is a major global health problem with increasing prevalence and significant risks of complications. This study aims to compare the effectiveness of Captopril 25 mg and Amlodipine 5 mg in lowering blood pressure among hypertensive patients. An analytical observational study with a cross-sectional design was conducted at Waruroyom Community Health Center, involving 70 patients divided equally into two groups. Data were collected using structured questionnaires, medication adherence sheets, and calibrated digital blood pressure monitors. Univariate and bivariate analyses were performed, including paired T-tests and Mann-Whitney tests. The results showed that both Captopril and Amlodipine effectively reduced systolic and diastolic blood pressure. However, Amlodipine 5 mg demonstrated a significantly greater reduction in diastolic blood pressure compared to Captopril 25 mg, while both drugs had similar effects on systolic blood pressure. The conclusion is that Amlodipine may be preferred for patients requiring greater diastolic blood pressure control, although both drugs are effective for systolic reduction.
Effectiveness of Gedong Gincu Mango Leaf Extract Gel (Mangifera indica L. var. Gedong gincu) on Cut Wound Healing in Male White Rats (Rattus norvegicus) of the Wistar Strain Loren, Azzahro Maharani; Wirandoko, Ignatius Hapsoro; Marfuati, Sri
GHMJ (Global Health Management Journal) Vol. 7 No. 3s (2024)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-741041

Abstract

Background: The Indonesia Basic Health Research data show the prevalence of wounds including incision/scratches/stab wounds reaches 20.1%. Natural herbal products play an important role in the wound healing process functioning as anti-inflammatories, antioxidants, antimicrobials, and collagen formation. Mango leaves are often considered waste even though they have many health benefits with the high content of coactive compounds, such as alkaloids, flavonoids, tannins, and saponins which are good for cut wound healing. The use of gel is more stable and controlled release compared to other topical preparations. Gedong Gincu mangoes originating from West Java have unique properties and they are marketed widely in some areas including Cirebon. Aims: This study aims to identify the most effective concentration of Gedong Gincu mango leaf extract on cut wound healing in male white rats (Rattus norvegicus) of the Wistar Strain. Methods: This study used a post-test-only control group design. The extract gel used three levels of concentration, namely 40%, 50%, and 60%. The positive control used 10% povidone iodine while the negative control used a gel base. The gel was applied to the cut wound twice a day for 14 days. Results: The average length of the cut wound was 0.916 cm, 0.912 cm, and 1.050 cm for concentration levels of 40%, 50%, and 60%. For the positive and negative controls, it reached 0.996 cm and 0.702 cm respectively. This indicates no significant difference in the length of the cut wound with a p-value of 0.121 (p>0.05). The wound healing process was effective at a concentration level of 60% as indicated by the disappearance of erythema and edema. Conclusion: Mango leaf extract gel (Mangifera indica L.var. Gedong Gincu) is effective in healing cut wounds with the disappearance of erythema and edema in male white rats (Rattus norvegicus) Wistar strain with a concentration of 60%. Received: 25 September 2024  |  Reviewed: 19 October 2024  |  Revised: 30 November 2024  |  Accepted: 15 December 2024.
The Relationship between Characteristics with Medication Adherence and Quality of Life among the Pulmonary Tuberculosis Patients at the Cirebon City Community Lung Health Center, Indonesia Dewi, Asri Permata; Zaidah, Niklah; Marfuati, Sri
GHMJ (Global Health Management Journal) Vol. 8 No. 3 (2025)
Publisher : Yayasan Aliansi Cendekiawan Indonesia Thailand (Indonesian Scholars' Alliance)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35898/ghmj-831245

Abstract

Background: Tuberculosis (TB) is one of the top ten causes of death worldwide, caused by the Mycobacterium tuberculosis germ. Adherence to medication is a key factor in successful treatment and efforts to improve the quality of life of TB patients. Aims: Analyzing the relationship between characteristics with medication adherence and quality of life of pulmonary TB patients at the Cirebon City Community Lung Health Center. Methods: This study used an analytic observation method with a Cross Sectional design. The measuring instruments used were medical records and questionnaires that had been tested for validity and reliability, with a total of 131 respondents of pulmonary TB patients at the Cirebon City Community Lung Health Center (BKPM). Results : The most common characteristics were adult age 90.8%, female gender 56.5%, secondary education 50.4%, student 28.2%, length of treatment at the advanced stage 59.5%, adherent to taking medication 87.0%, good quality of life 54.2%. Based on the Chi-Square test, the relationship between characteristics and drug compliance from age p-value=0.189, gender p-value=0.320, education p-value=0.447, occupation p-value=0.594, length of treatment p-value=0.014. The relationship between characteristics and quality of life from age p-value=0.688, gender p-value=0.550, education p-value=0.838, occupation p-value=0.519, length of treatment p-value=0.604. Based on the logistic regression test, the relationship between characteristics and drug compliance from age p-value=0.058, length of treatment p-value=0.006. Conclusion: There is no relationship between age, gender, education, and occupation with medication adherence (p>0.05). Whereas in the length of treatment there is a relationship with adherence to taking medication. There is no relationship between characteristics and quality of life of pulmonary TB patients (p>0.05). The characteristic most associated with adherence to taking medication is length of treatment (p=0.006). Future researchers are advised to explore other factors that may be related to medication adherence and quality of life in patients with pulmonary TB.
UJI AKTIVITAS DAYA HAMBAT FRAKSI N-HEKSAN, ETIL ASETAT, DAN BUTANOL BIJI MANGGA (MANGIFERA INDICA L.) VARIETAS GEDONG GINCU DALAM MENGHAMBAT AKTIVITAS BAKTERI STAPHYLOCOCCUS AUREUS ATCC 29213 Nasution, Aulia Ananta; Brajawikalpa, Rama Samara; Marfuati, Sri
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 9 No. 3 (2025): DESEMBER 2025
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v9i3.50563

Abstract

Kandungan metabolit sekunder didalam biji mangga (Mangifera indica L.) varietas gedong gincu memiliki banyak potensi yang belum diteliti secara maksimal, salah satunya sebagai antibakteri yang berpotensi menjadi salah satu alternatif pengobatan antibakteri Sehingga, diperlukan skrining fitokimia dan mengetahui efektivitas dari fraksi n-heksan, etil asetat, dan butanol biji mangga (Mangifera indica L.) varietas gedong gincu dalam menghambat pertumbuhan bakteri Staphylococcus aureus ATCC 29213. Penelitian eksperimental dengan rancangan post-test only control group design. Pembuatan konsentrasi dari fraksi n-heksan, etil asetat, dan butanol biji mangga (Mangifera indica L.) varietas Gedong Gincu (0,5%, 1%, 2%, 4%, dan 6%) diuji ke bakteri Staphylococcus aureus ATCC 29213 menggunakan metode pourplate untuk mengetahui daya hambat bakteri, yang kemudian dilakukan analisis statistik menggunakan uji normalitas Shapiro Wilk, uji parametrik One Way ANOVA, dan uji lanjutan PosHoc LSD. Senyawa metabolit sekunder yang terdapat pada fraksi n-heksan, etil asetat, dan butanol yaitu, flavonoid, alkaloid, tanin, steroid, saponin. Konsentrasi 6% dari masing-masing fraksi biji mangga (Mangifera indica L.) varietas gedong gincu memiliki rerata hasil pourplate yang signifikan dalam menghambat pertumbuhan bakteri (p<0,05). Fraksi etil asetat biji mangga (Mangifera indica L.) varietas gedong gincu konsentrasi 6% memiliki daya hambat paling efektif dibandingkan dengan fraksi lainnya dalam menghambat pertumbuhan bakteri Staphylococcus aureus ATCC 29213.
Co-Authors Amal, Ichlasul Dewi, Asri Permata Emallia Fitriani Hery Widijanto Ignatius Hapsoro Wirandoko Istisakinah, Rini Loren, Azzahro Maharani Nasution, Aulia Ananta Rama Samara Brajawikalpa Weni, Mustika Witri Pratiwi Zaidah, Niklah