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All Journal Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) The Journal of Palembang Nursing Studies
Khairi, Sabiah
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Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing

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Understanding obstructive sleep apnea Aini, Nur; Nguyen, Trung V.; Khairi, Sabiah
The Journal of Palembang Nursing Studies Vol. 3 No. 1 (2024): January 2024
Publisher : Palembang MediRose Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55048/jpns104

Abstract

Obstructive sleep apnea (OSA) is defined by repeated episodes of partial or complete upper airway collapse, obstructing breathing during sleep. OSA is a dangerous health condition with high mortality and morbidity. Due to the rising prevalence of obesity, OSA is on the rise in developing countries. Nevertheless, the exact number of OSA prevalence among Indonesian people is unrecognized for several reasons; for instance, low awareness of sleep disorder issues, unawareness of the symptoms and impact of OSA, limited access to polysomnography examinations, and considering snoring as a common condition. Long-term health effects, decreased sleep quality, psychological issues, and cognitive impairment are all linked to untreated OSA. Nurses can contribute to the management of OSA by conducting screening and assessment, providing health promotion to patients, and coordinating with other healthcare providers. This paper explores the prevalence of OSA, society’s perception of OSA, diagnostic or screening procedures, and treatment options for the effective management of OSA.
Identification of Biomarker for Stunting Through Prioritization of Gene-Assosiated Variants Wibowo, Anisa Devi Kharisma; Puspitaningrum, Anisa Nova; Ma’ruf, Muhammad; Irham, Lalu Muhammad; Supadmi, Woro; Kartikasari, Ayu Lifia Nur; Adikusuma, Wirawan; Chong, Rockie; Firman, Firman; Nugraha, Media Fitri Isma Isma; Siswanto, Lalu Muhammad Harmain; Khairi, Sabiah; Pranata, Satria
Media Farmasi: Jurnal Ilmu Farmasi Vol. 21 No. 1: March 2024
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v21i1.28297

Abstract

Stunting is a condition of impaired growth and development in children due to chronic nutritional disorders or infections. The risk factor for stunting is dominated by disease during 1000 days of life. The incidence of stunting in Indonesia is 21.6%, according to the Indonesian Nutrition Status Survey (SSGI) results. This study aimed to identify stunting biomarkers based on the priority scoring of gene variants. Identification of stunting risk genes used the Genome-Wide Association Studies (GWAS) approach and Haploreg v4.1. We found 33 genes that identifies as stunting risk gene. And then, we prioritize based on two functional annotation categories: missense-nonsense and cis-expression quantitative trait loci (cis-eQTL). Our analysis found 4 genes as biological stunting risk genes: MTRR, TTF1, CASP1, and CARD17. This research demonstrates the integration of genomic variants and bioinformatics approaches to reveal biological insights for stunting.
Co-Authors Chong, Rockie Firman Firman Heri Bahtiar Ilham Ilham Kartikasari, Ayu Lifia Nur Kusniyati Utami Lalu Muhammad Irham Ma’ruf, Muhammad Mulianingsih, Misroh Nguyen, Trung V. Nugraha, Media Fitri Isma Isma Nur Aini Pranata, Satria Puspitaningrum, Anisa Nova Siswanto, Lalu Muhammad Harmain Ulfiana, Ulfiana Wibowo, Anisa Devi Kharisma Winda Nurmayani M Wirawan Adikusuma Woro Supadmi