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All Journal JOURNAL LA MEDIHEALTICO MAHESA : Malahayati Health Student Journal Journal of Social Research QISTINA: Jurnal Multidisiplin Indonesia
Ivani, Ivani
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Journal : JOURNAL LA MEDIHEALTICO

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Cutaneus T-Cell Lymphoma in 53 Years Old Woman: Histopathological Features Ivani, Ivani; Murasmita, Alamanda; Mawardi, Prasetyadi; Oktavriana, Triasari
Journal La Medihealtico Vol. 5 No. 4 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i4.1495

Abstract

Cutaneous T-cell lymphomas (CTCLs) are clinically heterogeneous T-cell lymphomas that arise in the skin and are characterized by their clinical and pathological features. The pathogenesis of CTCL is not fully understood. The incidence of CTCL increases significantly with age, with a median age at diagnosis at about 55 years of age and a four-fold increase in incidence appreciated in patients over 70. A 53 year old woman presented with complaints of reddish spots and lumps on her left forearm and back which spread to her chest, stomach and legs. On examination, a lump the size of a golf ball was found on the left forearm and back as well as reddish spots that felt itchy and painful. Histopathological examination with HE staining showed proliferation of lymphoid follicles without a germinal center and monotonous cells of small to medium size partially surrounding the tubular glands in the dermis layer. Immunohistochemical examination revealed positive for CD 45 as well as CD 3 and negative for CD 20. A case of CTCL has been reported in a 53-year-old woman. Histopathological examination and immunohistochemistry are important to diagnose this disease.
Retrospective Study of Seborrhoic Dermatitis Patients at the Dermatology and Venereology Outpatient Installation Hidayati, Nurul; Irawanto, Muhammad Eko; Alia, Vrenda; Ivani, Ivani
Journal La Medihealtico Vol. 6 No. 1 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i1.1892

Abstract

Seborrheic dermatitis is a chronic superficial skin disorder occurs in 1-5% of the world's population with the symptom of erythematous plaque with slightly yellowish scaling and without clear border, it caused by multifactorial etiopathogenesis includes sebaceous gland secretion, Malassezia fungi colonization, and immune response. This study aims to determine the profile of seborrheic dermatitis patients in Dermatology and Venereology Outpatient Installation of Dr. Moewardi Surakarta General Hospital in January 2021 - December 2023 period. This study is a retrospective study using medical record data from seborrheic dermatitis patients who visited the Dermatology and Venereology Outpatient Installation of Dr. Moewardi Surakarta General Hospital from January 2021 to December 2023. The data collected included the number of cases, age group, gender, occupation, lesion location, and therapy options. Seborrheic dermatitis affected 76 people. Men are more likely to have seborrheic dermatitis than women; up to 43 patients (56.6%) and 30 patients (39.5%) are adults, the oldest age group with the condition. Up to 27 patients (35.5%) who suffer from this disease are private employees, 43 patients (56.6%) with comorbidities, and up to 65 patients (85.5%) frequently have lesion in their head. The most common therapy given was topical corticosteroid combined with anti-fungal in 38 patients (50.0%). In this study, the topical corticosteroids that were widely used were mometasone 0.1% cream and desoxymetasone 0.25% cream, topical antifungal that were widely used were ketoconazole 2% shampoo and ketoconazole 2% cream. Male adults are most likely to develop seborrheic dermatitis.
Co-Authors Alia, Vrenda Irawanto, Muhammad Eko Mulianto, Nur M Rachmat Murasih, Siti Murasmita, Alamanda Noviani, Laura Nurul Hidayati Prasetyadi Mawardi Refilina, Yenni Septiana, Riani Triasari Oktavriana