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All Journal JOURNAL LA MEDIHEALTICO MAHESA : Malahayati Health Student Journal Journal of Social Research
Noviani, Laura
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Humanities Computer Science & IT Dentistry Economics, Econometrics & Finance Education Health Professions Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary

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Profile of Shingles Patients in Outpatient Settings Dermatology and Venereology Noviani, Laura; Kariosentono, Harijono; Yasmin, Aulia; Kusumasari, Nila
Journal La Medihealtico Vol. 5 No. 4 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i4.1498

Abstract

Herpes zoster (HZ) is a latent varicella zoster virus (VZV) reactivation has been related to aging and immunocompromised condition that affects the skin and mucosa. It becomes increasingly common. However, studies on the clinical profile of HZ in Indonesia are still lacking. Objective of the study is to describe clinico-epidemiological profiles of HZ in Dr. Moewardi General Hospital Surakarta, Indonesia in the period of January 2018 – December 2022. We conducted a retrospective study using the medical records of patients visiting Dermatovenereology Outpatient Clinic of Dr. Moewardi General Hospital Surakarta from January 2018 to December 2022. 48 subjects included in this study 31 of them are females (65%). The subjects were dominated by those aged >50 years old (n:30; 63%). Herpes zoster mostly occurred at thoracal dermatome (n:22: 46%). Top three comorbidities were hypertension (n:10; 21%) followed by autoimmune diseases (n:9: 18%) and malignancy history (n; 6; 13%). Antiviral drugs (n:33; 69%) and antibiotic ointment (n:33; 69%) were the most therapy. More than 50% of subjects received anticonvulsant gabapentin (n:28; 58%) and one-fourth of subjects received analgesic (n:12; 25%). Herpes Zoster most affects middle adulthood population invo involving thoracal dermatome. Hypertension, autoimmune disease and history of malignancy are the common comorbidity. The main therapy of HZ is antivirus in combination with anticonvulsant and analgesic.
Sukralfat as a Therapy for Reducing Itching and Repairing the Skin Barrier: A Systematic Review Alia, Vrenda; Widhiati, Suci; Oktavriana, Triasari; Lidjaja, Lifesia Natali; Noviani, Laura
Journal La Medihealtico Vol. 5 No. 4 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i4.1508

Abstract

Sucralate is an aluminum salt from sucrose octasulfate that is known for its anti-ulcer activity, mucosal protection, and anti-mucositis potential. Recently, sucralfat has been used topically for the healing of various epithelial wounds, including ulcers, inflammatory dermatitis, mucositis, and burns. This systematic review aimed to evaluate the effectiveness of sucralfat as a topical therapy in reducing itching (pruritus) and improving the skin barrier. The analysis method used is Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA). A literature search was conducted on studies from 2004 to 2024 using keywords such as "sucralfate", "pruritus", "dermatitis", and "skin barrier" on PubMed, ProQuest, Science Direct, and Scopus databases. Inclusion criteria include topic relevance, research design, human subjects, and United Kingdom-speaking studies. Of the 141 articles found, 7 articles met the inclusion criteria. These studies involved a total of 605 subjects from different countries and used clinical trial methods and randomized controlled trials. The results showed that topical sucralfat was effective in reducing itching and improving the skin barrier in various skin conditions such as diaper dermatitis, chronic ulcers, and postoperative wounds. Sukralfat shows great potential in wound healing and skin barrier repair through the mechanism of protective layer formation, increased expression of epidermal growth factors, and anti-inflammatory properties. This effect indirectly helps reduce pruritus which often occurs due to damage to the skin barrier. Topical succulthate is effective in reducing itching and repairing the skin barrier, making it a promising therapy for a variety of inflammatory and ulcerative skin conditions.
Profile of Generalized Pustular Psoriasis Inpatient Installation at Dr. Moewardi General Hospital Surakarta from January 2018-December 2022 Hidayati, Nurul; Mulianto, Nurrachmat; Noviani, Laura; Lidjaja, Lifesia Natali
Journal La Medihealtico Vol. 5 No. 4 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i4.1584

Abstract

Generalized pustular psoriasis (GPP) is a form of psoriasis characterised by the presence of sterile pustules. Its prevalence is between 2 and 3.5% of the population worldwide and in Indonesia it is 2.5% of the population. It can cause severe physical and psychosocial distress affecting the patient's quality of life. Objective: To describe the profile of GPP patients treated in the inpatient installation of Dr. Moewardi Hospital, Surakarta in the period of January 2018-December 2022. A retrospective descriptive study was conducted using the secondary data of medical records of GPP patients treated in the inpatient installation of Dr. Moewardi Hospital from January 2018 to December 2022. Results: In the 5-year period, there were 23 GPP inpatients, predominated by female (78.26%) with the age ranged from 5 to 74 years old. Generalised pustular psoriasis mostly affected the age group of 41- 50 years old (26.04%). Most patients were hospitalized for 6–10 days (39.13%). The most common therapy was immunosuppressant (65.2%) followed by oral corticosteroids (26.1%) and zinc (17.4%). Most patients also received moisturizer therapy (56.5%). Generalised pustular psoriasis mostly affects people aged between 41 and 50 years old. Females are more prone to GPP. The therapy given are oral immunosuppressive regimens, oral corticosteroids, zinc, topical corticosteroids and moisturizers.
The Correlation between Abdominal Circumference and Psoriasis Vulgaris Incidence Alia, Vrenda; Irawanto, Muhammad Eko; Noviani, Laura; Ivani; Hidayati, Nurul
Journal of Social Research Vol. 4 No. 7 (2025): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v4i7.2601

Abstract

Psoriasis is a chronic inflammatory skin condition that is often associated with various comorbidities, including cardiovascular disease, obesity, diabetes mellitus, and psoriatic arthritis. Obesity, particularly abdominal obesity, is known to impact the effectiveness of psoriasis treatment. This study aims to explore the relationship between abdominal circumference and the incidence of psoriasis in patients at the Dermatology and Venereology Polyclinic of Dr. Moewardi Hospital, Surakarta. The objective of this research was to determine whether abdominal circumference (waist circumference) is associated with the incidence of psoriasis in patients at the Dermatology and Venereology Polyclinic. A cross-sectional study was conducted with 30 psoriasis vulgaris patients treated at the clinic from July to August 2024. Waist circumference was categorized as high or normal. Data analysis was performed using the Mann-Whitney test and logistic regression analysis. The majority of participants (70%) had high waist circumference. Statistically, only age showed a significant relationship with psoriasis incidence (p = 0.015). Gender, BMI status, and waist circumference did not significantly correlate with psoriasis incidence (p = 0.069, p = 0.789, p = 0.284, respectively). This study suggests that waist circumference does not have a significant relationship with the incidence of psoriasis. Future research could explore other factors contributing to psoriasis exacerbation, such as metabolic syndrome or visceral adiposity.
Decubital Candidiasis Mimicking Molluscum Contagiosum in an Unconscious Patient Noviani, Laura; Widhiati, Suci; Kariosentono, Harijono; Hidayati, Nurul; Alia, Vrenda
MAHESA : Malahayati Health Student Journal Vol 4, No 10 (2024): Volume 4 Nomor 10 (2024)
Publisher : Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/mahesa.v4i10.16573

Abstract

ABSTRACT Decubital candidiasis is a rare type of candidiasis often found in bedridden patients. Unlike decubital ulcer, it is also characterized with pustules and papules along with erythema, erosions, and scales. This lesion usually develops in the posterior thorax, lumbosacral, and gluteal region. In this case report, a patient was referred to us with generalized papules that was initially thought to be molluscum contagiosum after being admitted to intensive care unit (ICU). Keywords: Decubital Candidiasis, Candidiasis Miliaria, Candidiasis, Bedridden, Molluscum Contagiosum
Co-Authors Alia, Vrenda Aulia Yasmin, Aulia Irawanto, Muhammad Eko Ivani Kariosentono, Harijono Lidjaja, Lifesia Natali Nila Kusumasari Nurrachmat Mulianto Nurul Hidayati Triasari Oktavriana Widhiati, Suci