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Prognostic Factor of H-Zone Area in Basal Cell Carcinoma Mawardi, Prasetyadi; Prihadi, Irfany Arafiasetyanto; Irawanto, Muhammad Eko
Budapest International Research and Critics Institute-Journal (BIRCI-Journal) Vol 4, No 4 (2021): Budapest International Research and Critics Institute November
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i4.3210

Abstract

The study data were taken from secondary data obtained from medical records of BCC patients in Dr. Moewardi Hospital. The data were categorized based on gender, age, occupation, predilection/ location of tumor based on Baxter criteria, which divided the area into H-zone dan non-H-zone. H-zone was described to cover temporal, auricular, orbital, nasal, upper mandibular. Whereas the tumor size was divided into two, less than 2 cm and more than 2 cm. H-zone is a predilection with a high risk toward tumor biological characteristics, such as recurrence risk, aggressivity risk, and tumor infiltrative. The study obtained an ethics clearance from Health Research Ethics Committee of Dr. Moewardi Hospital with number 762/VIII/HREC/2021. The analysis was conducted to test whether there was a correlation or effect between two variables or more. In the study, the researcher also conducted statistics test to measure the correlation intensity of two variables or more by using Chi-square (X2), statistics test was conducted by using SPSS 22 for Windows. 99 patients were obtained from the medical records however only 70 patients who met the study requirements, who were subsequently categorized based on gender, age, occupation, BCC location and size, disease duration. 29 patients were excluded due to incomplete medical records (BCC location, BCC size, and treatment history were not found) non-primary BCC, data duplication, patients with more than one medical records, the result of histopathological test did not indicate seborrheic keratosis and Squamosa Cell Carcinoma. Based on the study there were more female patients compared to male patients. it discovered 45 female patients and 25 male patients (64,3% compared to 35,7%), with the age range was from 22-90 years, the BCC tumor was endured for more than 2 years, based on the education most of the patients had primary education background (elementary school and junior high school), the majority occupation of the patients was farmer (30%), followed by housewife (28,57%).
Hand Eczema in Nurses in COVID-19 Treatment Room: Frequency of Handwashing, Hand Sanitizer, Moisturizer, and Duration of Latex Gloves Use Rosmarwati, Ervina; Widhiati, Suci; Novriana, Dita Eka; Rahma, Alfina; Kariosentono, Harijono; Irawanto, Muhammad Eko; Kusumawardani, Arie; Ellistasari, Endra Yustin; Oktavriana, Triasari
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 34 No. 2 (2022): AUGUST
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V34.2.2022.92-98

Abstract

Background: The COVID-19 pandemic causes health workers to use level 2 and level 3 personal protective equipment. Hand washing and the use of latex gloves are important in limiting the spread of COVID-19, but they can potentially induce hand eczema and skin pH disturbance if used too frequently. Purpose: Determine the correlation between the frequency of handwashing and duration of using hand sanitizer and moisturizer as well as skin pH level on the incidence of hand eczema in nurses in the COVID-19 treatment room at RSUD Dr. Moewardi Surakarta. Methods: This cross-sectional study was conducted in the COVID-19 treatment room at RSUD Dr. Moewardi Surakarta with 90 nurses as subjects. A validated questionnaire carried out the frequency of handwashing, hand sanitizer, moisturizer, duration of using latex gloves, and hand eczema complaints. The subject's pH assessment was conducted after 4-5 hours in the COVID-19 treatment room. Data were analyzed bivariately with a Spearman rank correlation test. Result: There was a significant correlation with the incidence of hand eczema with the frequency of handwashing with soap (r=0.305 and p=0.003) and the duration of using latex gloves (r=0.328 and p=0.002) with a weak category correlation (r=0.200-0.399). The frequency of using hand sanitizer, moisturizer, and skin pH did not correlate with the incidence of hand eczema. Conclusion: Frequency of handwashing and the duration of using latex gloves correlated with the incidence of hand eczema, meanwhile frequency of using hand sanitizer, using moisturizer, and skin pH didn't correlate with the incidence of hand eczema.
HUBUNGAN TRANSEPIDERMAL WATER LOSS TERHADAP DERAJAT KEPARAHAN PADA PASIEN PSORIASIS VULGARIS Oktafiani, Anindya; Irawanto, Muhammad Eko
Media Dermato-Venereologica Indonesiana Vol 51 No 3 (2024): Media Dermato Venereologica Indonesiana
Publisher : Perhimpunan Dokter Spesialis Kulit dan Kelamin Indonesia (PERDOSKI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33820/mdvi.v51i3.437

Abstract

Pendahuluan: Psoriasis Vulgaris (PV) yaitu penyakit kulit yang bersifat kronis residif, ditandai adanya bercak eritema berbatas tegas disertai skuama tebal berwarna putih mengkilap dengan predileksi di daerah siku, lutut, punggung, kuku jari dan kulit kepala. Skala pengukuran yang paling umum digunakan dalam mengidentifikasi keparahan psoriasis adalah nilai Psoriasis Area Severity Index (PASI). Kerusakan barier kulit dan penyakit sistemik seperti psoriasis dapat menyebabkan gangguan transepidermal water loss (TEWL). Tujuan: mengetahui nilai TEWL terhadap derajat keparahan PV berdasarkan skor PASI di Rumah Sakit Dr. Moewardi. Metode: Penelitian ini adalah penelitian observasional analitik dengan studi potong lintang dengan metode consecutive sampling yang dilakukan pada pasien dengan diagnosis PV di Poliklinik Kulit dan Kelamin RS Dr. Moewardi Surakarta. Foto klinis pasien dilakukan untuk menilai skor PASI serta pengukuran TEWL menggunakan alat tewameter setelah dilakukan aklimatisasi. Semua data dianalisis secara statistik menggunakan Statistical Package for the Social Scient (SPSS) versi 21 kemudian dilakukan uji korelasi Spearman rank dan nilai p <0,05 dianggap terdapat hubungan signifikan. Hasil: Dua puluh enam pasien memenuhi kriteria inklusi. Berdasarkan skor PASI didapatkan 12 pasien dengan derajat psoriasis berat, 3 derajat sedang, dan 11 derajat ringan. Nilai TEWL pada psoriasis ringan, sedang, dan berat masing-masing adalah 8,59+5,82, 9,60+5,27, dan 16,65+6,26. Analisis statistik memperoleh korelasi yang sangat kuat antara TEWL dan tingkat keparahan PV (r=0,621; p=0,001). Kesimpulan: Terdapat hubungan yang signifikan antara TEWL dengan derajat keparahan PV yang dinilai berdasarkan skor PASI. 
Retrospective Study of Seborrhoic Dermatitis Patients at the Dermatology and Venereology Outpatient Installation Hidayati, Nurul; Irawanto, Muhammad Eko; Alia, Vrenda; Ivani, Ivani
Journal La Medihealtico Vol. 6 No. 1 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i1.1892

Abstract

Seborrheic dermatitis is a chronic superficial skin disorder occurs in 1-5% of the world's population with the symptom of erythematous plaque with slightly yellowish scaling and without clear border, it caused by multifactorial etiopathogenesis includes sebaceous gland secretion, Malassezia fungi colonization, and immune response. This study aims to determine the profile of seborrheic dermatitis patients in Dermatology and Venereology Outpatient Installation of Dr. Moewardi Surakarta General Hospital in January 2021 - December 2023 period. This study is a retrospective study using medical record data from seborrheic dermatitis patients who visited the Dermatology and Venereology Outpatient Installation of Dr. Moewardi Surakarta General Hospital from January 2021 to December 2023. The data collected included the number of cases, age group, gender, occupation, lesion location, and therapy options. Seborrheic dermatitis affected 76 people. Men are more likely to have seborrheic dermatitis than women; up to 43 patients (56.6%) and 30 patients (39.5%) are adults, the oldest age group with the condition. Up to 27 patients (35.5%) who suffer from this disease are private employees, 43 patients (56.6%) with comorbidities, and up to 65 patients (85.5%) frequently have lesion in their head. The most common therapy given was topical corticosteroid combined with anti-fungal in 38 patients (50.0%). In this study, the topical corticosteroids that were widely used were mometasone 0.1% cream and desoxymetasone 0.25% cream, topical antifungal that were widely used were ketoconazole 2% shampoo and ketoconazole 2% cream. Male adults are most likely to develop seborrheic dermatitis.
The Correlation between Abdominal Circumference and Psoriasis Vulgaris Incidence Alia, Vrenda; Irawanto, Muhammad Eko; Noviani, Laura; Ivani; Hidayati, Nurul
Journal of Social Research Vol. 4 No. 7 (2025): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v4i7.2601

Abstract

Psoriasis is a chronic inflammatory skin condition that is often associated with various comorbidities, including cardiovascular disease, obesity, diabetes mellitus, and psoriatic arthritis. Obesity, particularly abdominal obesity, is known to impact the effectiveness of psoriasis treatment. This study aims to explore the relationship between abdominal circumference and the incidence of psoriasis in patients at the Dermatology and Venereology Polyclinic of Dr. Moewardi Hospital, Surakarta. The objective of this research was to determine whether abdominal circumference (waist circumference) is associated with the incidence of psoriasis in patients at the Dermatology and Venereology Polyclinic. A cross-sectional study was conducted with 30 psoriasis vulgaris patients treated at the clinic from July to August 2024. Waist circumference was categorized as high or normal. Data analysis was performed using the Mann-Whitney test and logistic regression analysis. The majority of participants (70%) had high waist circumference. Statistically, only age showed a significant relationship with psoriasis incidence (p = 0.015). Gender, BMI status, and waist circumference did not significantly correlate with psoriasis incidence (p = 0.069, p = 0.789, p = 0.284, respectively). This study suggests that waist circumference does not have a significant relationship with the incidence of psoriasis. Future research could explore other factors contributing to psoriasis exacerbation, such as metabolic syndrome or visceral adiposity.
The Clinical Relevance of Serum Interleukin-21 in Grading Acne Vulgaris Dewi, Ayu Kusuma; Irawanto, Muhammad Eko; Kusumawardani, Arie; Dharmawan, Nugrohoaji; Mulianto, Nurrachmat
Journal of Social Research Vol. 4 No. 10 (2025): Journal of Social Research
Publisher : International Journal Labs

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55324/josr.v4i10.2795

Abstract

Acne vulgaris (AV) is an inflammatory skin disorder with multifactorial pathogenesis involving genetics, hormones, and immune dysregulation. Interleukin-21 (IL-21), a pleiotropic cytokine mainly secreted by T follicular helper and Th17 cells, has been implicated in various inflammatory skin diseases. However, its role in AV remains unclear. This cross-sectional study included 46 patients with AV, classified into mild (n=19), moderate (n=16), and severe (n=11) groups. Serum IL-21 levels were measured using an enzyme-linked immunosorbent assay (ELISA). Baseline characteristics were compared across groups, and interobserver reliability of AV severity grading was evaluated using Cohen’s kappa test. One-way ANOVA was applied to assess differences in IL-21 levels among severity groups, with a significance level set at p<0.05. The mean serum IL-21 level was highest in the severe AV group (303.53 pg/mL), followed by the moderate (223.7 pg/mL) and mild (213.2 pg/mL) groups. Although there was a trend toward increasing IL-21 levels with higher AV severity, statistical analysis revealed no significant difference among the three groups (p=0.130). Serum IL-21 levels were elevated in AV patients compared with previously reported healthy controls but did not differ significantly across severity levels. These findings suggest that IL-21 may play a role in the pathophysiology of AV, though it is not a reliable marker of clinical severity. Further case-control and tissue-based studies are needed to clarify its role.