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All Journal Jurnal Ilmu dan Teknologi Kesehatan Borneo Journal of Medical Laboratory Technology Muhammadiyah Journal of Midwifery (MyJM) Jurnal Laboratorium Khatulistiwa Jurnal Kesehatan Cendikia Jenius
Prasetyorini, Tri
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Veterinary

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Hubungan Antara Kadar Magnesium Serum Dengan HbA1c Pada Penderita Diabetes Mellitus Tipe 2 Di RSUP Fatmawati Jakarta: Correlation between MagnesiumSerum and HbA1c Levels in Patients with Type 2 Diabetes Mellitus at Fatmawati General Hospital Jakarta Prasetyorini, Tri; Lestari, Diah; Putri, Wandira Nur Eka
Borneo Journal of Medical Laboratory Technology Vol. 6 No. 1 (2023): Borneo Journal of Medical Laboratory Technology
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjmlt.v6i1.6089

Abstract

Diabetes Mellitus (DM) is a collection of symptoms that arise in a person caused by an increase in blood glucose levels due to a progressive decrease in insulin secretion. magnesium (Mg) plays an important role in insulin secretion, insulin binding, and homeostasis. Mg Serum level is an important factor in the etiology and development of macrovascular and microvascular complications in diabetes mellitus patients. HbA1c in DM patients is used to monitor glycemic control and predict the progression of diabetes complications. The purpose of this study was to determine the relationship between serum magnesium and HbA1c levels in patients with type 2 diabetes mellitus. The design of this study was an analytical observational study with a cross-sectional design. The data used are secondary data obtained from patients with type 2 diabetes mellitus at Fatmawati General Hospital for the period 2019 – 2020. The research sample used was 84 data for patients with type 2 diabetes mellitus. Analysis of the data used includes descriptive analysis and then hypothesis testing using the Spearman correlation test. The result of this study showed an association between serum magnesium and HbA1c levels with a value of p = 0,000 (p ≤ 0,05) and r = 0,513. The conclusion obtained in this study is that there is a strong negative pattern relationship between serum magnesium and HbA1c levels in type 2 diabetes mellitus.
PENURUNAN ANGKA KUMAN SEBELUM DAN SESUDAH BERKUMUR DENGAN POVIDONE IODINE Lestari, Diah; Ananda, Liandry Dea Dwi; Setiawan, Heru; Prasetyorini, Tri
Jurnal Ilmu dan Teknologi Kesehatan Vol 11 No 2 (2024): Maret 2024
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v11i2.1449

Abstract

Povidone-iodine is considered to have the broadest spectrum of antimicrobial action compared with other common antiseptics. Based on the application protocol of commercial Povidone Iodine (PVP-I) mouthwash to support a healthy lifestyle, PVP-I is commonly used in concentrations of 1.0% with a contact time of 30 seconds. The higher the concentration of antiseptic, the smaller the time needed to kill microbes, but the maximum limit of concentration and contact time needs to be considered to minimize the toxicity effects to remain safe, effective, and efficient. This study aims to determine the comparison of germ numbers before and after gargling with povidone-iodine mouthwash based on variations in the concentration of 0.2%, 0.4%, 0.6%, 0.8%, and 1% with variations in contact time of 15 and 30 seconds. The method of this research was an actual experiment with a pre-post-test design. Based on the Non-Parametric Friedman test with a confidence level of 95% (α = 0,05), there is a significant difference between the germs number before and after gargling with PVP-I in every variation of concentration and contact time (p-value = 0.00). This study concludes that PVP-I 0.2% concentration variation with 15 seconds of contact time has been effective in decreasing the number of germs.
Hubungan Antara Lama Penggunaan Kontrasepsi Suntik Depo Medroxy Progesteron Acetate (DMPA) dengan Kadar Kolesterol Total pada Akseptor KB Prasetyorini, Tri; Islami, Yasyavia Hatifah; Fajrunni’mah, Rizana; Karningsih, Karningsih
Muhammadiyah Journal of Midwifery Vol 1, No 2 (2020): Muhammadiyah Journal of Midwifery (MyJM)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (271.728 KB) | DOI: 10.24853/myjm.1.2.37-44

Abstract

Latar belakang: jumlah penduduk terbanyak di dunia posisi ke-4 adalah Indonesia. Upaya untuk menekan jumlah pertumbuhan penduduk yaitu dengan program Keluarga Berencana (KB). Secara nasional pengguna KB yang paling banyak adalah KB suntik Depo Medroxy Progesteron Acetate (DMPA) yaitu lebih dari 50% dari jumlah peserta KB aktif. DMPA yang mengandung hormon Progesteron dapat mempengaruhi metabolisme lemak, khususnya lipoprotein. Lama pemakaian kontrasepsi suntik lebih dari 1 tahun akan mengakibatkan ketidak seimbangan hormon estrogen dan progesteron yang berakibat penurunan HDL dan peningkatan LDL sehingga akan meningkatkan kadar kolesterol total. Tujuan: diketahuinya hubungan antara lama penggunaan kontrasepsi suntik DMPA dengan kadar kolesterol total pada akseptor KB DMPA. Metode: jenis penelitian yang digunakan observasional analitik cross sectional dengan jumlah sampel sebanyak 35 responden. Uji statistik yang digunakan adalah uji chi-square dengan tingkat kepercayaan 95%.  Hasil: menunjukan bahwa nilai p sebesar 0,011 (p0,05). Hal ini berarti bahwa terdapat hubungan antara lama penggunaan kontrasepsi suntik Depo Medroxy Progesteron Acetate (DMPA) dengan kadar kolesterol total pada akseptor KB. Sehingga semakin lama penggunaan kontrasepsi DMPA maka semakin meningkatkan kadar kolesterol. Kesimpulan: terdapat hubungan antara lama penggunaan kontrasepsi suntik DMPA dengan kadar kolesterol total.
GAMBARAN KADAR UREUM DAN KREATININ PENDERITA GANGGUAN JIWA YANG MENDAPAT TERAPI OBAT ANTIPSIKOTIK DI RSKD DUREN SAWIT JAKARTA TIMUR Prasetyorini, Tri; Salbiah, Salbiah; Purwanti, Angki; Pani, Silvia Septi
Jurnal Laboratorium Khatulistiwa Vol 8, No 2 (2025): Mei 2025
Publisher : poltekkes kemenkes pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30602/jlk.v8i2.1861

Abstract

Gangguan jiwa masih menjadi masalah sosial dan kesehatan yang jumlahnya masih banyak di Indonesia khususnya di Jakarta. Banyak dari penderita gangguan jiwa belum memiliki akses terhadap perawatan efektif dan juga banyak yang mengalami stigma dan diskriminasi. Gangguan jiwa umumnya ditandai dengan kerusakan emosi, pikiran dan perilaku, oleh karena itu penderita gangguan jiwa akan mendapatkan terapi obat antipsikotik untuk mengurangi gejala kekambuhan, namun konsumsi obat dengan dosis besar dan jangka waktu yang lama dapat berpengaruh terhadap penurunan sistem fungsi ginjal yang ditandai dengan kenaikan kadar ureum dan kreatinin. Penelitian ini bertujuan untuk mengetahui gambaran kadar ureum dan kreatinin penderita gangguan jiwa yang mendapat terapi obat antipsikotik di RSKD Duren Sawit. Metode penelitian ini bersifat deskriptif kuantitatif dengan mengambil 110 data sekunder dari catatan rekam medik di RSKD Duren Sawit periode Januari 2023 – April 2024. Hasil penelitian menunjukkan bahwa sebagian besar penderita gangguan jiwa adalah laki-laki (73%) dengan rentang usia 21-40 tahun (51%), penderita gangguan jiwa sebagian besar sudah mengkonsumsi obat lebih dari 6 tahun (52%), penderita gangguan jiwa sebagian besar mengkonsumsi jenis obat antipsikotik atipikal (92%). Hasil penelitian dapat disimpulkan dari 110 penderita gangguan jiwa kadar ureum sebagian besar masih normal (77%) dan hasil penelitian kadar kreatinin sebagian besar juga kadarnya masih normal (82%).Gangguan jiwa masih menjadi masalah sosial dan kesehatan yang jumlahnya masih banyak di Indonesia khususnya di Jakarta. Banyak dari penderita gangguan jiwa belum memiliki akses terhadap perawatan efektif dan juga banyak yang mengalami stigma dan diskriminasi. Gangguan jiwa umumnya ditandai dengan kerusakan emosi, pikiran dan perilaku, oleh karena itu penderita gangguan jiwa akan mendapatkan terapi obat antipsikotik untuk mengurangi gejala kekambuhan, namun konsumsi obat dengan dosis besar dan jangka waktu yang lama dapat berpengaruh terhadap penurunan sistem fungsi ginjal yang ditandai dengan kenaikan kadar ureum dan kreatinin. Penelitian ini bertujuan untuk mengetahui gambaran kadar ureum dan kreatinin penderita gangguan jiwa yang mendapat terapi obat antipsikotik di RSKD Duren Sawit. Metode penelitian ini bersifat deskriptif kuantitatif dengan mengambil 110 data sekunder dari catatan rekam medik di RSKD Duren Sawit periode Januari 2023 – April 2024. Hasil penelitian menunjukkan bahwa sebagian besar penderita gangguan jiwa adalah laki-laki (73%) dengan rentang usia 21-40 tahun (51%), penderita gangguan jiwa sebagian besar sudah mengkonsumsi obat lebih dari 6 tahun (52%), penderita gangguan jiwa sebagian besar mengkonsumsi jenis obat antipsikotik atipikal (92%). Hasil penelitian dapat disimpulkan dari 110 penderita gangguan jiwa kadar ureum sebagian besar masih normal (77%) dan hasil penelitian kadar kreatinin sebagian besar juga kadarnya masih normal (82%).
Pengaruh Minum Air Putih terhadap Hasil Pemeriksaan Mikroskopis (Sedimen) Urin Prasetyorini, Tri; Purwanti , Angki; Djayaningrat, Husyain; Putri, Tasha Dwisarah
Jurnal Kesehatan Cendikia Jenius Vol. 1 No. 2 (2024): April
Publisher : CV. CENDIKIA JENIUS INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70920/jenius.v1i2.41

Abstract

Chronic Kidney Disease (CKD) is a kidney disorder characterized by abnormalities in kidney structure or function. Based on research results, cases of kidney failure experienced by adults are caused by kidney stones and urinary tract infections which can be caused by foods containing purine, drinking water containing hard water, frequent holding in urination and lack of fluids in the body which can result in dehydration. The aim of this study was to determine whether or not there was an effect of drinking water on urine sediment examination. This research was conducted at the Matraman Community Health Center, the research design in this study was Pre-Experimental, namely a study by carrying out experimental activities to determine the effect of drinking water on the results of microscopic examination (sediment) of urine by providing 2 liters of water or minerals/day once. administered before and after drinking water. This study used the Federer formula with 35 respondents and the results showed no significant differences between urine sediment examination before and after administering 2 liters of water, except for calcium oxalate crystals and uric acid. In conclusion, drinking 2 liters of water for one day has no effect on the results of microscopic examination (sediment) of urine and there are no significant differences between urine sediment examination before and after giving 2 liters of water/day, except for calcium oxalate and uric acid crystals in urine. It is recommended that further research follow up on any factors (influences) that can influence the microscopic examination (sediment) of urine.
Profile of Serum Creatinine Levels with Creatinine Clearance Test (CCT) of Patients with Type 2 Diabetes Mellitus at Budhi Asih Hospital in 2021 Prasetyorini, Tri; Lestari, Diah; Anzalinna, Aliffiya; Suratun, Suratun
Jurnal Ilmu dan Teknologi Kesehatan Vol 10 No 1 (2022): September 2022
Publisher : Poltekkes Kemenkes Jakarta III

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32668/jitek.v10i1.865

Abstract

Diabetes Mellitus (DM) is a group of metabolic diseases with hyperglycemia characteristics that can lead to kidney complications. One of them is Diabetic Nephropathy which is a complication of microvascular damage and its monitoring is done by checking serum creatinine and creatinine clearance test (CCT). The purpose of this study was to determine the relationship between serum creatinine levels and creatinine clearance test (CCT) in patients with type 2 DM. Perform a serum creatinine examination which is used as the basis for calculating CCT. From 53 data on type 2 DM patients who had high serum creatinine levels, 49 (92.5%) people, 51 (96.2%) people with low CCT levels. The results of Spearman's correlation statistical test showed a correlation between serum creatinine levels and CCT. The strength of the correlation is moderate, and the correlation shows a negative direction with a correlation coefficient (r) of -0.389. It can be concluded that the higher the serum creatinine level, the lower the CCT value, so DM patients must control blood glucose regularly in order to prevent a decrease in kidney function that can lead to complications.
Co-Authors Ananda, Liandry Dea Dwi Angki Purwanti, Angki Anzalinna, Aliffiya Diah Lestari, Diah Djayaningrat, Husyain Fajrunni’mah, Rizana Heru Setiawan Islami, Yasyavia Hatifah Karningsih Karningsih Pani, Silvia Septi Purwanti , Angki Putri, Tasha Dwisarah Putri, Wandira Nur Eka Salbiah Salbiah, Salbiah Suratun Suratun