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Synthesis of Eco-Friendly Bioplastic from Banana Hump Starch and Sugarcane Bagasse Cellulose Filler with Fish Scale Chitosan Agustina, Ayu Safitri; Jumrah, Elfira; Abubakar, Andi Nur Fitriani
Jurnal Akta Kimia Indonesia (Indonesia Chimica Acta) Volume 16, No 2: December 2023
Publisher : Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70561/ica.v16i2.29891

This study aims to make environmentally friendly bioplastics. This is because the use of plastic creates a plastic waste problem which is very difficult to handle. After all, it is difficult to decompose. Excessive use of plastic will be bad for the safety of the earth in the future. One of the innovations to be developed is the synthesis of environmentally friendly bioplastics. The basic ingredients for making bioplastics come from starch, cellulose, and chitosan. The process of making bioplastics uses several formulations including A0 (control), A1, A2 and A3. The research results showed that the biodegradability test was good for the A3 formula and the water absorption test was 3.77% and water resistance was 96.2%.

Formulation of Watermelon Rind (Citrullus vulgaris schard) and Secang (Caesalpinia sappan L.) Jam as Functional Food Rich in Antioxidants Aziz, Rahmawati; Jumrah, Elfira; Agustina, Ayu Safitri; Abubakar, Andi Nur Fitriani; Zulkarnain, A. Mutiara
Indonesian Journal of Chemical Research Vol 11 No 2 (2023): Edition for September 2023
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598//ijcr.2023.11-rah

The body's immune system is one of the natural defenses in the human body, functioning to ward off various diseases, including those that emerged after the Covid-19 pandemic. One plant with potential as an antioxidant and easily found in the environment is watermelon. Jam made from watermelon rind and secang wood, with various formulations, namely 100% watermelon rind: 0% secang (F1), 90% watermelon rind: 10% secang (F2), 80% watermelon rind: 2% secang (F3), and 70% watermelon rind: 3% secang (F4), is expected to possess good antioxidant properties. A promising antioxidant formulation for watermelon rind jam and secang is the one with 70% watermelon rind and 30% secang (F4), having an IC50 value of 144.27 g/mL, which is classified as a moderate antioxidant. Among the four jam formulations, panelists preferred the jam formulation (F4) without the addition of sweetened condensed milk in terms of color and texture. However, for the jam formulation (F4) with the addition of sweetened condensed milk, panelists favored it in terms of aroma and taste. The jam formulation (F4) meets the quality standards for fruit jam based on INS 3746:2008, including total plate count, arsenic, and tin categories.

Formulation of Lahuna Leave (Eupatorium odoratum) and Sirih Leave Extract (Piper betle L.) as Antiseptic Liquid Soap Jumrah, Elfira; Abubakar, Andi Nur Fitriani; Agustina, Ayu Safitri; Karneng, Syahdam; Gusti, Herdie Idriawien
Indonesian Journal of Chemical Research Vol 10 No 3 (2023): Edition for January 2023
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598//ijcr.2023.10-jum

Infectious diseases caused by microorganisms are the main cause of high morbidity and mortality in the world. One of the plants that have the potential as an antiseptic is a lahuna leaf. Lahuna leaves contain active antibacterial compounds and the addition of betel leaf to the liquid soap formulations can strengthen the activity of the antiseptic produced. The purpose of this research is to test the effectiveness of liquid soap formulations of lahuna leaves and betel leaves as an antiseptic. The methods used include phytochemical screening, physical observation of liquid soap formulations, and antibacterial activity tests using agar diffusion methods. The results of the phytochemical analysis showed that lahuna leaves contain flavonoids, tannins, terpenoids, and alkaloids, while betel leaves contain flavonoids, saponins, tannins, terpenoids, and alkaloids. The liquid soap formulation of lahuna leaves and betel leaves has a clear yellow color, distinctive aroma, liquid form, rough taste, and lots of foam and has very strong inhibition against Staphylococcus aureus which is characterized by clear zones formed for each formulation I (22.4 mm), formulation II (21.8 mm) and formulation III (20.1 mm). These results indicate the potential of liquid soap formulations of lahuna leaves and betel leaves as antiseptic soap.

Comparison of Air Contact And Distilled Water Distribution Method in The Conversion of Cao to Ca(OH)2 As A Precursor Hydroxyapatite Synthesis Firnanelty, Firnanelty; Abubakar, Andi Nur Fitriani; Qurniawan, Anas; Syam, M. A.
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 8, No 3 (2023): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkpk.v8i3.78348

Eggshells containing CaCO3 have potential as bioceramics for several tissue engineering applications. The content of CaCO3 converted into Ca(OH)2 can be used as a precursor to implant material. The purpose of the study was to compare two methods of converting CaO into Ca(OH)2 as the primary material for making hydroxyapatite. The method used is direct contact with air and dissolution with water. Hydroxyapatite synthesis using Ca(OH)2 is calcined from CaCO3 with a sintering temperature of 900 °C. The result of calcination is in the form of CaO. The stages of obtaining Ca(OH)2 by converting CaO using two methods, namely direct contact with air and dissolution with water. The XRD characterization results obtained that Ca(OH)2 results from direct contact with air show the formation of phase (portlandite), which is characterized by its presence at the highest typical 2θ angles = 18.18°, 28.68°, 34.30°, 47.40°, 50.92°, 54.16°, and 62.62°. The XRD Ca(OH)2 pattern with the distilled water distribution process shows the formation of a phase (portlandite) characterized by its presence at angles of 2θ = 18.18°, 28.68°, 34.30°, 47.40°, 50.92°, 54.16°, and 62.62 °. The results of FTIR Ca(OH)2 characterization of air contact and water dissolution showed strong O-H functional groups at wave numbers 3643 cm-1 and 3642 cm-1, C-O groups at 1487 cm-1 and 1483 cm-1. This suggests that both methods can convert CaO to Ca(OH)2, which synthesizes hydroxyapatite. The hydroxyapatite characterization results obtained have met the standard.

Testing Antibacterial Activities and Characterization of Chemical Compounds Composing Essential Oil from Lemo Cuco Fruit Peel (Citrus sp.) Febryanti, Amalyah; Ilyas, Asriani; Abubakar, Andi Nur Fitriani
Pharmaceutical Journal of Indonesia Vol. 10 No. 1 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2024.010.01.10

Lemo Cuco (Citrus sp.) is one of the plant species of Rutaceae grown in the districts of Bone and Sinjai, South Sulawesi. This fruit is commonly used for food as scent, cough reliever and as fishy and meaty deodorizing. The peel has a special scent indicating presence of essensial oil components. This study aims to evaluate antibacterial activities and and to characterize compounds in ethanol extract dan n-hexane extract Lemo Cuco (Citrus sp.). This study used the soxhletation, and fitokimia text and the characterization of components in extracts with GC-MS and antibacterial activities using the disc diffusion method. The results obtained from the study were testing the antibacterial activities of Lemo Cuco (Citrus sp.) peel extract against the Staphylococcus aureus and Salmonella typhi bacteria. Inhibition of ethanol and n-hexane extract against the bacteria S. aureus included weak, medium, and strong category according to the concentrations (20%, 10%, 5%, 2.5% and 1.25%), whereas inhibitory against S. typhi bacteria in n-heksane included weak, medium, and strong category, whereas ethanol extract included medium and weak category, even not active. Based on the results of phytochemical identification of the Lemo Cuco (Citrus sp.), peel extract indicated existence of flavonoids, phenolic, steroids, terpenoids, alkaloids and saponins compound. n-heksane exctract contained special fraction saponins, whereas ethanol exctract was nothing. Characterization using GC-MS indicated existence of monoterpenoid and sesquiterpenoid compound. Thus, ethanol and n-hexane extracts of lemon cuco fruit skin have the potential to inhibit Staphylococcus aureus bacteria.

Testing Antibacterial Activities and Characterization of Chemical Compounds Composing Essential Oil from Lemo Cuco Fruit Peel (Citrus sp.) Febryanti, Amalyah; Ilyas, Asriani; Abubakar, Andi Nur Fitriani
Pharmaceutical Journal of Indonesia Vol. 10 No. 1 (2024)
Publisher : Brawijaya University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.pji.2024.010.01.10

Lemo Cuco (Citrus sp.) is one of the plant species of Rutaceae grown in the districts of Bone and Sinjai, South Sulawesi. This fruit is commonly used for food as scent, cough reliever and as fishy and meaty deodorizing. The peel has a special scent indicating presence of essensial oil components. This study aims to evaluate antibacterial activities and and to characterize compounds in ethanol extract dan n-hexane extract Lemo Cuco (Citrus sp.). This study used the soxhletation, and fitokimia text and the characterization of components in extracts with GC-MS and antibacterial activities using the disc diffusion method. The results obtained from the study were testing the antibacterial activities of Lemo Cuco (Citrus sp.) peel extract against the Staphylococcus aureus and Salmonella typhi bacteria. Inhibition of ethanol and n-hexane extract against the bacteria S. aureus included weak, medium, and strong category according to the concentrations (20%, 10%, 5%, 2.5% and 1.25%), whereas inhibitory against S. typhi bacteria in n-heksane included weak, medium, and strong category, whereas ethanol extract included medium and weak category, even not active. Based on the results of phytochemical identification of the Lemo Cuco (Citrus sp.), peel extract indicated existence of flavonoids, phenolic, steroids, terpenoids, alkaloids and saponins compound. n-heksane exctract contained special fraction saponins, whereas ethanol exctract was nothing. Characterization using GC-MS indicated existence of monoterpenoid and sesquiterpenoid compound. Thus, ethanol and n-hexane extracts of lemon cuco fruit skin have the potential to inhibit Staphylococcus aureus bacteria.

Synthesis and Characterization of Nickel Nanoparticles: Biological and Photocatalytic Properties Fadliah, Fadliah; Raya, Indah; Ahmad, Ahyar; Taba, Paulina; Burhanuddinnur, Muhammad; Gaffar, Maming; Putri, Tri Widayati; Nur, Arfiani; Abubakar, Andi Nur Fitriani; Munadi, Rachmin; Majid, Ahmad Fudhail; Pratama, Irham; Yasser, M.; Jarre, Sulistiani; Karim, Harningsih
Indonesian Journal of Chemistry Vol 25, No 1 (2025)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.90034

The potential uses of ecologically benign nickel nanoparticle manufacturing in various sectors, such as biomedicine, energy storage, and catalysis, have garnered much interest. This paper covers green approaches to nickel nanoparticle manufacturing, which integrate natural substances as stabilizing and reducing agents with eco-friendly processes. Phytochemicals derived from bacteria, microorganisms, and plant leaf extracts can convert nickel ions (Ni2+) into nickel nanoparticles. Room temperature is used for the synthesis procedure, and neither dangerous compounds nor unusual reaction conditions are used. Using a variety of analytical methods, the resultant nickel nanoparticles were characterized. We also investigate the possibility of using the generated nickel nanoparticles as a cytotoxic, photocatalytic, antioxidant, and antibacterial agents. The antimicrobial activity of nickel nanoparticles demonstrates their potent antibacterial properties, while their antioxidant activity demonstrates their capacity to combat free radicals effectively. Furthermore, nickel nanoparticles' cytotoxic activity demonstrates their capacity to kill cancer cells, and their photocatalytic activity demonstrates their efficiency in breaking down organic contaminants. This review highlights the value of ecologically benign synthetic methods and creates new avenues for developing nickel nanoparticle applications in health and the environment.

Skrining Fitokimia dan Uji Aktivitas Antibakteri Sediaan Lotion Ekstrak Daun Lahuna (Chromolaena odorata) Terhadap Bakteri Staphylococcus aureus Alda, Nurfadhilah; Astuti, Kartika Novi; Jumrah, Elfira; Abubakar, Andi Nur Fitriani
CERATA Jurnal Ilmu Farmasi Vol 16 No 1 (2025): Cerata Jurnal Ilmu Farmasi
Publisher : Universitas Muhammadiyah Klaten

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61902/cerata.v16i1.1418

Daun lahuna atau yang dikenal dengan nama ilmiah Chromolaena odorata adalah tumbuhan digunakan secara tradisional untuk mengobati luka, obat batuk, dan penyakit kulit. Tujuan dari penelitian ini adalah mengetahui potensi ekstrak daun lahuna sebagai sumber senyawa aktif dan aktivitas antibakteri sediaan lotion ekstrak daun lahuna terhadap bakteri Staphylococcus aureus. Pada skrining fitokimia, senyawa metabolit sekunder yang terdapat pada ekstra etanol daun lahuna adalah fenolik, flavonoid, saponin, tanin, dan alkaloid. Formulasi sediaan lotion dibuat tiga variasi konsentrasi yaitu 2 gram (F1), 3 gram (F2), dan 4 gram (F3). Hasil menunjukkan bahwa aktivitas antibakteri pada bakteri Staphlococcus aureus setelah diformulasikan dalam sediaan lotion memiliki zona hambat berturut-turut 12.428 mm, 12.89 mm, dan 14.255 mm.

Formulation and Evaluation of Balm Stick Preparations from the Essential Oil of Eucalyptus resinifera Leaves Ramadhan, Eka Sujisno; Wulan, Mustika Candra; Marsandah, Marsandah; Abubakar, Andi Nur Fitriani; Agustina, Ayu Safitri; Karneng, Syahdam Safitri; Yuliana, Hasri Safitri
Jurnal Beta Kimia Vol 5 No 2 (2025): Volume 5 Number 2, November 2025
Publisher : Universitas Nusa Cendana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35508/jbk.v5i2.24366

Balm is one of the pharmaceutical products with an ointment base that uses essential oils as one of the ingredients in its formulation. One of the essential oils found in Indonesia is Eucalyptus resinifera essential oil. In Indonesia, the use of E. resinifera leaf essential oil in balm stick formulations has not yet been reported. The purpose of this study was to formulate and characterize a balm stick preparation from E. resinifera leaf essential oil for the development of health products. The methods used included the formulation of E. resinifera essential oil balm with four essential oil concentrations (0%, 15%, 20%, and 25%) and evaluation of the preparations through homogeneity, spreadability, adhesion, pH, and skin irritation tests. The results showed that the best formula was Formula III, containing 20% essential oil, which met the requirements for a good balm preparation based on the results of the homogeneity test (homogeneous), spreadability test (3.9 cm), adhesion test (>1 minute), pH test (4.6), and skin irritation test (no irritation observed), and was also the most preferred according to the organoleptic test.

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