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All Journal Global Medical and Health Communication Jurnal Keperawatan Padjadjaran Indonesian Journal of Medicine Jurnal Biomedika dan Kesehatan SmartComp Jurnal Info Kesehatan
Putri, Desy Puspa
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Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health

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Correlation of Interleukin-6 Level with Neutrophil to Lymphocyte Ratio and Disease Severity in COVID-19 Patients Apriningsih, Hendrastutik; Prabowo, Nurhasan Agung; Reviono, Reviono; Anindita, Brigitta Devi; Myrtha, Risalina; Putri, Desy Puspa; Hermawati, Berty Denny
Global Medical & Health Communication (GMHC) Vol 11, No 1 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v11i1.9643

Abstract

Coronavirus disease 2019 (COVID-19) causes severe acute respiratory disease in humans and has spread rapidly worldwide since its first identification in December 2019. The neutrophil-to-lymphocyte ratio (NLR) describes the balance between the severity of inflammation and the immune system to be used as an important systemic inflammatory marker. Rapid progression of clinical deterioration is characterized by severe respiratory symptoms related to high levels of pro-inflammatory cytokines, like interleukin-6 (IL-6), indicating that the occurrence of cytokine storms leads to increased mortality. This study aims to assess the correlation between IL-6 and NLR in predicting the severity of COVID-19. This prospective cohort study was conducted at the COVID-19 ward of Universitas Sebelas Maret Hospital in August–September 2021. This study involved 66 COVID-19 patients >18 years old with asymptomatic to critical degree and Charlson Comorbidity Index (CCI) value ≤3. Examination of laboratory parameters and serum IL-6 was carried out when the patient entered the Emergency Room. Statistical test with Pearson’s correlation test, significant if p<0.05. There is no significant correlation between IL-6 and NLR with p=0.56 and r=0.08, and a strong correlation between IL-6 and disease severity with p=0.000 and r=0.454. The conclusion is that IL-6 does not correlate with NLR and strongly correlates with disease severity in COVID-19 patients.
A Rare Case Report of Gastric Adenocarcinoma with Pneumoperitoneum after Jejunostomy Feeding Sukmagautama, Coana; Asaduddin, Aiman Hilmi; Syahrizal, Maulana Firdaus; Khasan, Arif Nur; Putri, Desy Puspa
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.704

Abstract

Background: Gastric cancer is the third highest cancer mortality globally. This malignancy can result in emergency complications such as gastric perforation which results in pneumo­peritoneum. Currently, there are not many case reports which describe pneumoperitoneum in gastric cancer. In this report, we describe a gastric adenocarcinoma with pneumoperitoneum following jejunostomy feeding. Case Presentation: A 54 years old male presented with abdominal pain, black-colored feces, and body weight decrease as much as 22 kg within a month. The physical examination revealed anemic conjunctiva, distended abdomen with abdominal pain, and pale skin. On the lab examination, the hemoglobin level was 9.9 mg/dL. The peripheral blood smear showed signs of iron deficiency anemia caused by chronic process. An endoscopic examination and biopsy showed a gastric mass with well-moderately differentiated gastric adenocarcinoma. The three positions abdominal x-ray incidentally found that the patient had pneumoperitoneum. Results: Patient was diagnosed with Adenocarcinoma Gaster based on a gastric mass biopsy with hematoxylin-eosin staining. Then, the patient was treated with jejunostomy feeding. Thoracic and 3-position abdominal X-ray examinations revealed incidental findings of pneumoperitoneum and small bowel obstruction. Conclusion: Jejunostomy feeding in gastric cancer patient may result in pneumoperitoneum as a complication. Gastric adenocarcinoma followed by iron deficiency anemia from chronic process post jejunostomy feeding was found with pneumoperitoneum complication.
Thrombosis of the inferior vena cava and acute kidney injury in dengue shock syndrome: A rare case with unique nursing challenges Prabowo, Nurhasan Agung; Sari, Yulia; Putri, Desy Puspa; Habibah, Sopia Nur; Rachmah, Azkia; Hartono, Hartono
Jurnal Keperawatan Padjadjaran Vol. 12 No. 3 (2024): Jurnal Keperawatan Padjadjaran
Publisher : Faculty of Nursing Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkp.v12i3.2641

Abstract

Background: Dengue Shock Syndrome (DSS) is a severe complication of dengue fever that can lead to life-threatening conditions such as thrombosis and acute kidney injury (AKI). These rare complications highlight the importance of early recognition and multidisciplinary management to improve clinical outcomes. Purpose: This case study aims to report and discuss the clinical management and outcomes of a patient with DSS complicated by inferior vena cava thrombosis and AKI, focusing on nursing interventions and therapeutic strategies. Methods: This manuscript reports a case by utilizing the patient’s baseline data, clinical progression, and treatment outcomes. A middle-aged male patient presented to the emergency department with high fever, shock, and signs of plasma leakage. Laboratory and imaging findings confirmed DSS with AKI and inferior vena cava thrombosis. The patient received fluid resuscitation, inotropic support, anticoagulation therapy, and multidisciplinary care, including close nursing monitoring. Results: After seven days of hospitalization, the patient showed significant improvement, with resolution of shock, normalization of platelet count, and recovery of renal function. Comprehensive nursing care, including vital sign monitoring, medication management, and patient education, played a pivotal role in the recovery process. At a follow-up visit on day 12, the patient demonstrated full recovery with no complications. Conclusions: This case highlights the importance of early diagnosis and a multidisciplinary approach, including cautious anticoagulation therapy, to effectively manage DSS with thrombosis and AKI. Integrating nursing interventions and strict monitoring were crucial to achieving positive clinical outcomes. This report provides valuable insights into managing similar cases in endemic areas.
Implementasi Algoritma Naïve Bayes dan Certainty Factor pada Sistem Pakar Deteksi Penyakit Diabetes Mellitus Tahap Awal Ridwan, Alfian Junior; Atina, Vihi; Hartanti, Dwi; Putri, Desy Puspa
Smart Comp :Jurnalnya Orang Pintar Komputer Vol 14, No 2 (2025): Smart Comp: Jurnalnya Orang Pintar Komputer
Publisher : Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/smartcomp.v14i2.7327

Abstract

Penyakit diabetes mellitus merupakan masalah kesehatan yang semakin memprihatinkan di Indonesia, termasuk di Kota Surakarta. Rumah Sakit Universitas Sebelas Maret Surakarta adalah salah satu rumah sakit yang memiliki visi untuk meningkatkan layanan kesehatan dalam pemeriksaan penyakit diabetes mellitus. Proses pemeriksaan dan deteksi penyakit diabetes mellitus di Rumah Sakit Universitas Sebelas Maret Surakarta biasanya dilakukan dengan cara mengumpulkan riwayat rekam medis, pemeriksaan dan tes medis serta pemeriksaan tambahan lainya. Data yang sudah terkumpul disimpan dalam catatan medis fisik dalam bentuk kertas yang disimpan dalam arsip. Sistem tersebut memiliki masalah dalam hal keterbatasan aksesibilitas serta membutuhkan ruang penyimpanan yang besar, data manual yang begitu banyak menyebabkan tidak efisien dalam hal analisis penyakit diabetes mellitus dengan cepat dan tepat. Tujuan penelitian ini adalah untuk mengembangkan sebuah sistem pakar yang menggunakan algoritma Naïve Bayes dan Certainty Factor dalam deteksi penyakit diabetes mellitus pada tahap awal dengan studi kasus di Rumah Sakit Universitas Sebelas Maret Surakarta. Penulis pada penelitian ini menggunakan Metode SDLC (System Development Life Cycle) model Waterfall, pada proses implementasi sistem pakar menggunakan bahasa pemrograman php dan basis data MySQL. Hasil dari penelitian ini adalah sebuah sistem pakar yang memiliki fitur manajemen data pasien, data pengguna, data gejala, data penyakit, basis pengetahuan, data training dan konsultasi pasien. Sistem pakar dapat membantu tenaga medis dalam melakukan manajemen sistem pada penyakit diabetes mellitus dan membantu pasien dalam mendeteksi penyakit diabetes mellitus secara mandiri dan memberikan pengetahuan tentang penyakit tersebut.
ST-Depresi pada Infark Miokard Akut dengan Elevasi Segmen ST–Pentingnya Perubahan Resiprokal pada Elevasi Segmen ST yang Minimal Myrtha, Risalina; Wijayanto, Matthew Aldo; Putri, Desy Puspa; Hermawati, Berty Denny
Jurnal Biomedika dan Kesehatan Vol 7 No 3 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.339-344

Abstract

Coronary artery disease remains the leading cause of mortality globally. Management of ST-elevation myocardial infarction (STEMI) starts from the point of first medical contact. Time delay to treatment influences the mortality in STEMI patients. The aim of this study is to underline the importance of reciprocal ECG changes in helping diagnosis STEMI with subtle ST elevation. We present an obese and hypertensive male patient with atypical symptoms of MI and was diagnosed as peptic ulcer. The ECG showed subtle ST elevation in inferior ECG leads and reciprocal changes in I and aVL. Highly sensitive troponin was elevated. Serial ECG showed evolution, thus revealed acute inferior MI. Successful percutaneous coronary intervention was performed. ECG is one of the most important diagnosis tools in STEMI and a cornerstone to direct the decision to immediate reperfusion therapy. Minimal ST-elevation often leads to inappropriate diagnosis, thus delayed the time to reperfusion. A study shows that 11-23% of STEMI do not reach the cutoff for accepted ECG criteria. In a study of infarctions with minimal ST-elevation, reciprocal changes are reported in 58% of all cases. Reciprocal ECG changes is extremely useful to help identifying STEMI in the absence of obvious ST-elevation on ECG
Comparison of Severity in Diabetic Ulcer Patients with and Without Sepsis Maydiana, Siti Roisya Aga; Nurhayatun, Evi; Putri, Desy Puspa
JURNAL INFO KESEHATAN Vol 22 No 2 (2024): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol22.Iss2.1221

Abstract

Diabetes mellitus patients in Central Java grow yearly. According to data provided by the Central Java Health Department in 2019, Diabetes mellitus ranks second as the largest non-communicable disease (NCD), covering 13,4% of the total NCD patients. The prevalence of diabetic ulcers is 15-25% of all diabetes mellitus patients in Indonesia, which concerns the author regarding the possible increase of the diabetic ulcer population in Central Java. The severity of diabetic ulcers depends on various factors, including infection and complications. The most common complication is sepsis, a systemic infection often arising from local infections that are not appropriately treated, causing progressive damage and increasing mortality rates. This study aims to examine the comparison of ulcer severity in diabetic ulcer patients with sepsis and non-sepsis complications using Meggitt Wagner's criteria. This study utilizes an analytic observational study using a cross-sectional approach. The author sampled 126 patients diagnosed with Diabetic Ulcers in 2022 at Dr. Moewardi General Hospital for this study, using a purposive sampling method. The research was conducted by looking at the patient's medical record data, and data analysis using SPSS software. The test used in this research includes a Parametric T-independent test and a Pearson bivariate relationship test. This study shows that the comparison of ulcer severity in diabetic ulcer patients with sepsis and without sepsis was statistically significant (p-value = 0.000002). The mean of the group with sepsis (3.4127) was greater than the group without sepsis (2.5238). In conclusion, the comparison of ulcer severity in diabetic ulcer patients with sepsis and without sepsis is significant. We recommend future researchers include patients’ comorbidities, total hospitalization time, and detailed information on drug use and patient adherence to treatment in their research for more nuanced findings.                 
Co-Authors Anindita, Brigitta Devi Apriningsih, Hendrastutik Asaduddin, Aiman Hilmi Atina, Vihi Dwi Hartanti Habibah, Sopia Nur Hartono Hartono Hermawati, Berty Denny Khasan, Arif Nur Maydiana, Siti Roisya Aga Myrtha, Risalina Nurhayatun, Evi Prabowo, Nurhasan Agung Rachmah, Azkia Reviono Reviono Ridwan, Alfian Junior Sukmagautama, Coana Syahrizal, Maulana Firdaus Tamaulina Br Sembiring Wijayanto, Matthew Aldo