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All Journal Global Medical and Health Communication Jurnal Keperawatan Padjadjaran Smart Medical Journal Indonesian Journal of Medicine Jurnal Biomedika dan Kesehatan Smart Society Empowerment Journal SmartComp Jurnal Info Kesehatan
Putri, Desy Puspa
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Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Dentistry Electrical & Electronics Engineering Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Correlation of Interleukin-6 Level with Neutrophil to Lymphocyte Ratio and Disease Severity in COVID-19 Patients Apriningsih, Hendrastutik; Prabowo, Nurhasan Agung; Reviono, Reviono; Anindita, Brigitta Devi; Myrtha, Risalina; Putri, Desy Puspa; Hermawati, Berty Denny
Global Medical & Health Communication (GMHC) Vol 11, No 1 (2023)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/gmhc.v11i1.9643

Abstract

Coronavirus disease 2019 (COVID-19) causes severe acute respiratory disease in humans and has spread rapidly worldwide since its first identification in December 2019. The neutrophil-to-lymphocyte ratio (NLR) describes the balance between the severity of inflammation and the immune system to be used as an important systemic inflammatory marker. Rapid progression of clinical deterioration is characterized by severe respiratory symptoms related to high levels of pro-inflammatory cytokines, like interleukin-6 (IL-6), indicating that the occurrence of cytokine storms leads to increased mortality. This study aims to assess the correlation between IL-6 and NLR in predicting the severity of COVID-19. This prospective cohort study was conducted at the COVID-19 ward of Universitas Sebelas Maret Hospital in August–September 2021. This study involved 66 COVID-19 patients >18 years old with asymptomatic to critical degree and Charlson Comorbidity Index (CCI) value ≤3. Examination of laboratory parameters and serum IL-6 was carried out when the patient entered the Emergency Room. Statistical test with Pearson’s correlation test, significant if p<0.05. There is no significant correlation between IL-6 and NLR with p=0.56 and r=0.08, and a strong correlation between IL-6 and disease severity with p=0.000 and r=0.454. The conclusion is that IL-6 does not correlate with NLR and strongly correlates with disease severity in COVID-19 patients.
A Rare Case Report of Gastric Adenocarcinoma with Pneumoperitoneum after Jejunostomy Feeding Sukmagautama, Coana; Asaduddin, Aiman Hilmi; Syahrizal, Maulana Firdaus; Khasan, Arif Nur; Putri, Desy Puspa
Indonesian Journal of Medicine Vol. 9 No. 3 (2024)
Publisher : Masters Program in Public Health, Sebelas Maret University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/theijmed.2024.9.3.704

Abstract

Background: Gastric cancer is the third highest cancer mortality globally. This malignancy can result in emergency complications such as gastric perforation which results in pneumo­peritoneum. Currently, there are not many case reports which describe pneumoperitoneum in gastric cancer. In this report, we describe a gastric adenocarcinoma with pneumoperitoneum following jejunostomy feeding. Case Presentation: A 54 years old male presented with abdominal pain, black-colored feces, and body weight decrease as much as 22 kg within a month. The physical examination revealed anemic conjunctiva, distended abdomen with abdominal pain, and pale skin. On the lab examination, the hemoglobin level was 9.9 mg/dL. The peripheral blood smear showed signs of iron deficiency anemia caused by chronic process. An endoscopic examination and biopsy showed a gastric mass with well-moderately differentiated gastric adenocarcinoma. The three positions abdominal x-ray incidentally found that the patient had pneumoperitoneum. Results: Patient was diagnosed with Adenocarcinoma Gaster based on a gastric mass biopsy with hematoxylin-eosin staining. Then, the patient was treated with jejunostomy feeding. Thoracic and 3-position abdominal X-ray examinations revealed incidental findings of pneumoperitoneum and small bowel obstruction. Conclusion: Jejunostomy feeding in gastric cancer patient may result in pneumoperitoneum as a complication. Gastric adenocarcinoma followed by iron deficiency anemia from chronic process post jejunostomy feeding was found with pneumoperitoneum complication.
Thrombosis of the inferior vena cava and acute kidney injury in dengue shock syndrome: A rare case with unique nursing challenges Prabowo, Nurhasan Agung; Sari, Yulia; Putri, Desy Puspa; Habibah, Sopia Nur; Rachmah, Azkia; Hartono, Hartono
Jurnal Keperawatan Padjadjaran Vol. 12 No. 3 (2024): Jurnal Keperawatan Padjadjaran
Publisher : Faculty of Nursing Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/jkp.v12i3.2641

Abstract

Background: Dengue Shock Syndrome (DSS) is a severe complication of dengue fever that can lead to life-threatening conditions such as thrombosis and acute kidney injury (AKI). These rare complications highlight the importance of early recognition and multidisciplinary management to improve clinical outcomes. Purpose: This case study aims to report and discuss the clinical management and outcomes of a patient with DSS complicated by inferior vena cava thrombosis and AKI, focusing on nursing interventions and therapeutic strategies. Methods: This manuscript reports a case by utilizing the patient’s baseline data, clinical progression, and treatment outcomes. A middle-aged male patient presented to the emergency department with high fever, shock, and signs of plasma leakage. Laboratory and imaging findings confirmed DSS with AKI and inferior vena cava thrombosis. The patient received fluid resuscitation, inotropic support, anticoagulation therapy, and multidisciplinary care, including close nursing monitoring. Results: After seven days of hospitalization, the patient showed significant improvement, with resolution of shock, normalization of platelet count, and recovery of renal function. Comprehensive nursing care, including vital sign monitoring, medication management, and patient education, played a pivotal role in the recovery process. At a follow-up visit on day 12, the patient demonstrated full recovery with no complications. Conclusions: This case highlights the importance of early diagnosis and a multidisciplinary approach, including cautious anticoagulation therapy, to effectively manage DSS with thrombosis and AKI. Integrating nursing interventions and strict monitoring were crucial to achieving positive clinical outcomes. This report provides valuable insights into managing similar cases in endemic areas.
Implementasi Algoritma Naïve Bayes dan Certainty Factor pada Sistem Pakar Deteksi Penyakit Diabetes Mellitus Tahap Awal Ridwan, Alfian Junior; Atina, Vihi; Hartanti, Dwi; Putri, Desy Puspa
Smart Comp :Jurnalnya Orang Pintar Komputer Vol 14, No 2 (2025): Smart Comp: Jurnalnya Orang Pintar Komputer
Publisher : Politeknik Harapan Bersama

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30591/smartcomp.v14i2.7327

Abstract

Penyakit diabetes mellitus merupakan masalah kesehatan yang semakin memprihatinkan di Indonesia, termasuk di Kota Surakarta. Rumah Sakit Universitas Sebelas Maret Surakarta adalah salah satu rumah sakit yang memiliki visi untuk meningkatkan layanan kesehatan dalam pemeriksaan penyakit diabetes mellitus. Proses pemeriksaan dan deteksi penyakit diabetes mellitus di Rumah Sakit Universitas Sebelas Maret Surakarta biasanya dilakukan dengan cara mengumpulkan riwayat rekam medis, pemeriksaan dan tes medis serta pemeriksaan tambahan lainya. Data yang sudah terkumpul disimpan dalam catatan medis fisik dalam bentuk kertas yang disimpan dalam arsip. Sistem tersebut memiliki masalah dalam hal keterbatasan aksesibilitas serta membutuhkan ruang penyimpanan yang besar, data manual yang begitu banyak menyebabkan tidak efisien dalam hal analisis penyakit diabetes mellitus dengan cepat dan tepat. Tujuan penelitian ini adalah untuk mengembangkan sebuah sistem pakar yang menggunakan algoritma Naïve Bayes dan Certainty Factor dalam deteksi penyakit diabetes mellitus pada tahap awal dengan studi kasus di Rumah Sakit Universitas Sebelas Maret Surakarta. Penulis pada penelitian ini menggunakan Metode SDLC (System Development Life Cycle) model Waterfall, pada proses implementasi sistem pakar menggunakan bahasa pemrograman php dan basis data MySQL. Hasil dari penelitian ini adalah sebuah sistem pakar yang memiliki fitur manajemen data pasien, data pengguna, data gejala, data penyakit, basis pengetahuan, data training dan konsultasi pasien. Sistem pakar dapat membantu tenaga medis dalam melakukan manajemen sistem pada penyakit diabetes mellitus dan membantu pasien dalam mendeteksi penyakit diabetes mellitus secara mandiri dan memberikan pengetahuan tentang penyakit tersebut.
ST-Depresi pada Infark Miokard Akut dengan Elevasi Segmen ST–Pentingnya Perubahan Resiprokal pada Elevasi Segmen ST yang Minimal Myrtha, Risalina; Wijayanto, Matthew Aldo; Putri, Desy Puspa; Hermawati, Berty Denny
Jurnal Biomedika dan Kesehatan Vol 7 No 3 (2024)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2024.v7.339-344

Abstract

Coronary artery disease remains the leading cause of mortality globally. Management of ST-elevation myocardial infarction (STEMI) starts from the point of first medical contact. Time delay to treatment influences the mortality in STEMI patients. The aim of this study is to underline the importance of reciprocal ECG changes in helping diagnosis STEMI with subtle ST elevation. We present an obese and hypertensive male patient with atypical symptoms of MI and was diagnosed as peptic ulcer. The ECG showed subtle ST elevation in inferior ECG leads and reciprocal changes in I and aVL. Highly sensitive troponin was elevated. Serial ECG showed evolution, thus revealed acute inferior MI. Successful percutaneous coronary intervention was performed. ECG is one of the most important diagnosis tools in STEMI and a cornerstone to direct the decision to immediate reperfusion therapy. Minimal ST-elevation often leads to inappropriate diagnosis, thus delayed the time to reperfusion. A study shows that 11-23% of STEMI do not reach the cutoff for accepted ECG criteria. In a study of infarctions with minimal ST-elevation, reciprocal changes are reported in 58% of all cases. Reciprocal ECG changes is extremely useful to help identifying STEMI in the absence of obvious ST-elevation on ECG
Comparison of Severity in Diabetic Ulcer Patients with and Without Sepsis Maydiana, Siti Roisya Aga; Nurhayatun, Evi; Putri, Desy Puspa
JURNAL INFO KESEHATAN Vol 22 No 2 (2024): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol22.Iss2.1221

Abstract

Diabetes mellitus patients in Central Java grow yearly. According to data provided by the Central Java Health Department in 2019, Diabetes mellitus ranks second as the largest non-communicable disease (NCD), covering 13,4% of the total NCD patients. The prevalence of diabetic ulcers is 15-25% of all diabetes mellitus patients in Indonesia, which concerns the author regarding the possible increase of the diabetic ulcer population in Central Java. The severity of diabetic ulcers depends on various factors, including infection and complications. The most common complication is sepsis, a systemic infection often arising from local infections that are not appropriately treated, causing progressive damage and increasing mortality rates. This study aims to examine the comparison of ulcer severity in diabetic ulcer patients with sepsis and non-sepsis complications using Meggitt Wagner's criteria. This study utilizes an analytic observational study using a cross-sectional approach. The author sampled 126 patients diagnosed with Diabetic Ulcers in 2022 at Dr. Moewardi General Hospital for this study, using a purposive sampling method. The research was conducted by looking at the patient's medical record data, and data analysis using SPSS software. The test used in this research includes a Parametric T-independent test and a Pearson bivariate relationship test. This study shows that the comparison of ulcer severity in diabetic ulcer patients with sepsis and without sepsis was statistically significant (p-value = 0.000002). The mean of the group with sepsis (3.4127) was greater than the group without sepsis (2.5238). In conclusion, the comparison of ulcer severity in diabetic ulcer patients with sepsis and without sepsis is significant. We recommend future researchers include patients’ comorbidities, total hospitalization time, and detailed information on drug use and patient adherence to treatment in their research for more nuanced findings.                 
Association Between Glycated Hemoglobin (HbA1c) Levels and Mean Platelet Volume (MPV) in Patients with Type 2 Diabetes Mellitus Utami, Aloysia Flower Lula; Prabowo, Nurhasan Agung; Hermawati, Berty Denny; Putri, Desy Puspa; Argaheni, Niken Bayu
JURNAL INFO KESEHATAN Vol 24 No 1 (2026): JURNAL INFO KESEHATAN
Publisher : Research and Community Service Unit, Poltekkes Kemenkes Kupang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31965/infokes.Vol24.Iss1.2334

Abstract

Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia, which can trigger inflammatory responses contributing to various vascular complications. Inflammation plays a key role in the pathogenesis of DM-related complications through mechanisms involving oxidative stress and activation of NF-κB signaling, which influence platelet production and activity. Given inconsistent findings regarding the association between HbA1c and mean platelet volume (MPV) in previous studies, this study aims to investigate the relationship between HbA1c and MPV, a pro-thrombotic and inflammatory marker, in patients with type 2 diabetes mellitus. This study is an analytical observational study with a cross-sectional approach. Data were collected from the medical records of Universitas Sebelas Maret (UNS) Hospital, Indonesia, using purposive sampling. HbA1c and MPV data were obtained from patients’ medical records over the past year. Statistical analysis was performed using the Shapiro–Wilk normality test and Pearson correlation test. A total of 38 samples were included in the study. The mean HbA1c level was 10.37% (range: 6.50–16.10), while the mean MPV was 9.38 fL (range: 7.30–12.50). Pearson correlation test showed a significant relationship between HbA1c and MPV (r = 0.467; p = 0.003). There is a significant positive correlation between HbA1c and MPV in patients with type 2 diabetes mellitus.      
Case Report: Pneumonia Provocate Thyroid Storm in Graves Disease Hermawati, Berty Denny; Prabowo, Nurhasan Agung; Putri, Desy Puspa; Myrtha, Risalina; Apriningsih, Hendrastutik
Smart Medical Journal Vol 6, No 1 (2023): April
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v6i1.68166

Abstract

Introduction: A thyroid crisis is an endocrine emergency involving many organ systems and can be fatal to the patient's survival. Although cases of thyroid crisis are rare, the mortality rate is significant which reaches 20–50%. The presence of comorbidities such as pneumonia infection increases the risk of death dramatically. Infection is a factor that can trigger thyroid crisis and exacerbate thyrotoxicosis. This condition of thyroid crisis most often occurs in people with hyperthyroidism caused by Graves' disease. We present the case of a patient with Graves' disease, aged 22 years, who developed a thyroid crisis due to community-acquired pneumonia infection. This study aims to provide a case report regarding the thyroid crisis due to pneumonia.Results: We carried out a physical and some appropriate supporting examinations to confirm the diagnosis. Wayne's index was 26, indicating hyperthyroidism. Assessment with Burch-Wartofsky obtained a score of 45, indicating suspicion of a thyroid storm. Then supportive care was provided to the patient. The community-acquired pneumonia as a triggering factor was treated with antibiotics. Thyrotoxicosis conditions were treated with antithyroid, beta-blocker, and glucocorticoid drugs. The patient's condition improved after treatment.Conclusion: It is crucial to detect and treat thyroid storm as quickly as possible since it has a high mortality rate. Wayne's score is useful for identifying hyperthyroidism based on clinical symptoms. The Burch-Wartofsky Point Scale scores are used to diagnose thyroid storms. Thyroid storm should be managed according to PERKENI (Perkumpulan Endokrinologi Indonesia) and ATA (American Thyroid Association) recommendations. This case serves as an example of how to make a proper diagnosis and treatment to prevent morbidity and death due to thyroid crisis.
Thyroid Crisis and Diabetic Ketoacidosis in Uncontrolled Diabetes Putri, Desy Puspa; Prabowo, Nurhasan Agung; Hermawati, Berty Denny
Smart Medical Journal Vol 6, No 3 (2023): December
Publisher : Faculty of Medicine Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13057/smj.v6i3.66806

Abstract

Introduction: Thyroid crisis is a medical emergency that causes damage to various organs of the body so that proper diagnosis and immediate treatment are needed. Excess thyroid hormone also affects blood sugar metabolism, especially in diabetic patients. The occurrence of thyroid crisis in conjunction with diabetic ketoacidosis (DKA) is rare, and the exact pathogenesis is still being investigated. We report a case of thyroid crisis in a DKA patient.Case Presentation: A 35-year-old woman was brought by her family to the ER due to a loss of consciousness since 6 hours before admission to the hospital. The patient was said to have complained of fever, shortness of breath, palpitations since the previous day. The patient has a history of uncontrolled Type 2 Diabetes Mellitus (DM) since 5 years ago. Physical examination showed somnolence, blood pressure 120/72 mmHg, pulse rate 126 beats per minute, irregular, respiratory rate 28 breaths per minute, fast and deep breaths. Investigations showed blood sugar 320 mg/dL, uncompensated metabolic acidosis, ketonuria. The patient received DKA therapy, but her consciousness and pulse rate had not improved. TSH levels was low with an increase in fT4 levels, with the Burch-Wartofsky score supporting a thyroid crisis. The patient then received treatment for thyroid crisis and her clinical condition showed significant improvement.Conclusion: The occurrence of thyroid crisis along with DKA is a life-threatening emergency. Untreated hyperthyroid induce severe hyperglycemia and causes acute condition in both organs.  
Telusur Infeksi Tuberkulosis Laten pada Populasi Berisiko dan Investigasi Kontak pada Lingkup Puskesmas Gajahan Surakarta Apriningsih, Hendrastutik; Hapsari, Brigitta Devi Anindita; Siregar, Sihsusetyaningtyas Tiominar; Prabowo, Nurhasan Agung; Putri, Desy Puspa; Landiasari, Debby Andina; Mirshanti, Farahdila; ., Yunita; Fahmiati, Cahyani
Smart Society Empowerment Journal Vol 5, No 3 (2025): November
Publisher : Faculty of Medicine, Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/ssej.v5i3.105855

Abstract

Pendahuluan: Indonesia merupakan salah satu dari negara dengan beban Tuberkulosis (TB) tertinggi di dunia. Penemuan Infeksi TB laten (ITBL) dan pemberian Terapi Pencegahan Tuberkulosis (TPT) merupakan salah satu strategi dalam upaya menurunkan beban TB nasional. Program Penanggulangan TB merubah strategi penemuan pasien TB aktif secara intensif dan masif berbasis keluarga dan Masyarakat. Pelacakan populasi berisiko dan investigasi kontak memiliki peran penting pada strategi ini. Diagnosis ITBL saat ini menggunakan Tuberculin Skin Test (TST) atau Interferon Gamma-Release Assay (IGRA). Metode: Tujuan kegiatan pengabdian ini untuk memberikan penyuluham mengenai ITBL dan pemberian TPT, serta peningkatan penemuan kasus ITBL pada investigasi kontak dan populasi berisiko yaitu pasien Diabetes Melitus (DM) di lingkup Puskesmas Gajahan Surakarta. Dilakukan pre-test dan post-test untuk evaluasi kegiatan penyuluhan tersebut.Hasil dan pembahasan: Pemeriksaan tes tuberkulin pada 26 responden IK didapatkan 11 responden dengan hasil positif (42,3%) dan 25 responden dengan penyakit komorbid DM didapatkan 10 responden (40,0%) hasil positif.Kesimpulan: Kegiatan telusur ITBL pada investigasi kontak dan populasi DM sangat diperlukan untuk membantu penurunan angka kejadian TB aktif.
Co-Authors Anindita, Brigitta Devi Apriningsih, Hendrastutik Argaheni, Niken Bayu Asaduddin, Aiman Hilmi Atina, Vihi Dwi Hartanti Fahmiati, Cahyani Habibah, Sopia Nur Hapsari, Brigitta Devi Anindita Hartono Hartono Hermawati, Berty Denny Khasan, Arif Nur Landiasari, Debby Andina Maydiana, Siti Roisya Aga Mirshanti, Farahdila Myrtha, Risalina Nurhayatun, Evi Prabowo, Nurhasan Agung Rachmah, Azkia Ratih Puspita Febrinasari Reviono Reviono Ridwan, Alfian Junior Siregar, Sihsusetyaningtyas Tiominar Sukmagautama, Coana Syahrizal, Maulana Firdaus Tamaulina Br Sembiring Utami, Aloysia Flower Lula Wijayanto, Matthew Aldo Yunita .