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All Journal MANAJEMEN HUTAN TROPIKA Journal of Tropical Forest Management Jurnal Lanskap Indonesia Jurnal Ilmu Tanah dan Lingkungan (Journal of Soil Science and Environment) Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Pendas : Jurnah Ilmiah Pendidikan Dasar JEMSI (Jurnal Ekonomi, Manajemen, dan Akuntansi) Jurnal Pengabdian Mandiri Jurnal Penelitian Ekonomi Manajemen dan Bisnis Journal of Economic Education and Entrepreneurship Studies
Andi Gunawan
medical student of brawijaya university
Agriculture, Biological Sciences & Forestry Humanities Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Environmental Science Languange, Linguistic, Communication & Media Social Sciences Other

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The Correlation Between IL-1β and IL-10 Levels in Estimating The Risk of Febrile Seizures Andi Gunawan; M Muid; Hidayat Suyudi; Barlianto wisnu; Krisni Subandiyah
Journal of Tropical Life Science Vol. 4 No. 2 (2014)
Publisher : Journal of Tropical Life Science

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Abstract

Febrile seizures are the most common forms of seizures in children with fever. A data from clinical and experimental studies suggest the potential role of immune generate products in their genesis. The balance between proinflammatory (IL-1β) and anti-inflammatory (IL-10) cytokines influences the regulation of infections and plays a role in the pathogenesis of febrile seizures. In existing literature, there is no research on the correlation between IL-1β and IL-10 levels as well as the ratio of IL-1β to IL-10 in estimating the risk of febrile seizures in seizure prone children aged between 3 months and 5 years. In this study, IL-1β, IL-10 levels and ratio of IL-1β to IL-10 in the risk of febrile seizures were investigated, and respondents were divided into three groups: febrile seizures, febrile without seizures and healthy children without histories of febrile seizure. This study has used A cross-sectional design, and each group had 17 co-respondents. IL-1β and IL-10 levels were measured by ELISA. Data were analyzed by SPSS 15. Findings showed there were significant differences between IL-1β and IL-10 as well as in the ratio of IL-1β to IL-10 between febrile seizure patients and healthy children. It was concluded that there were significant correlations between IL-1β and IL-10 levels as well as IL-1β to IL-10 ratios in estimating the risk of febrile seizures.
Co-Authors . Mariski A. Desi Vio Alvionita Andi Nur Fadillah Andi Nurazizah A Ardi Faiz Alfianshah Arlian Efrata Tarigan Asnimawati, Asnimawati Barlianto wisnu Dedy Darnaedi Durrotun Nafisah Dwiyani, Dwiyani Fitri Ramadani Gunarso Primada Aji Hadi S Alikodra Hidayat Suyudi Ilham Ilham Krisni Subandiyah Laksono Trisnantoro M Muid M. Fadel Alfayed Idham Meilani Purwanti Muh. Akbar Muhammad Alfi Maulana Ammas Muhammad Ardiansyah NIZAR NASRULLAH Rustan DM Sahrul Gunawan