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All Journal Prosiding Seminar Nasional Sains Dan Teknologi Fakultas Teknik Nexus Kedokteran Klinik Jurnal Keterapian Fisik Indian Journal of Forensic Medicine & Toxicology Journal of Information Systems for Public Health Berita Kedokteran Masyarakat Jurnal Akademika Baiturrahim Jambi
Ari Probandari
Department of Public Health Sciences, Faculty of Medicine, Universitas Sebelas Maret, Surakarta 57126, Indonesia
Computer Science & IT Decision Sciences, Operations Research & Management Engineering Health Professions Medicine & Pharmacology Nursing Physics Public Health

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Journal : Nexus Kedokteran Klinik

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Efek Anestesi Inhalasi Sevofluran dan Isofluran Terhadap Frekuensi Nadi Aulia Nurul Fatimah; Mulyo Hadi Sudjito; Ari Probandari
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Anesthesia is an important part of the surgery. Sevoflurane and isoflurane are two inhalation anesthesia drugs have been commonly used. During anesthesia, one of indicators should be monitored is frequency of pulse. This research aimed to know the effects of these two drugs to the frequency of pulse. Methods: This research was an analytical observational research with the approach of cross sectional. The sample was taken by consecutive sampling after being selected based on the inclusion and exclusion criteria. Totally, 50 patients were divided into two groups of inhalation anesthetic sevoflurane and inhalation anesthetic sevoflurane and isoflurane. Data was analyzed with independent t test. Results: The p values on t-independent test in the early phase of the pulse frequency, phase induction and phase intubation were 0.04; 0.00; 0.02, and of the phase 5 of incision, 10of incision and 15of incision were 0.02; 0,0; 0.03. This results showed statistical significant of mean of pulse-frequency difference between sevoflurane and isoflurane in each of phase of inhalation anesthesia. Conclusions: Both sevoflurane and isoflurane influence the frequency of pulse. The mean of pulse frequency by isoflurane is higher than sevoflurane. However, inhalation anesthesia sevoflurane provides better stability than isoflurane. Keywords: Anesthetic Inhalation, Frequency of Pulse, Isoflurane, Sevoflurane
Comparison of Effect between Inhalative Anesthetics with Isoflurane and Sevoflurane on Oxygen Saturation Prabuwinoto Setiawan; M.H. Sudjito; Ari Probandari
Nexus Kedokteran Klinik Vol 2, No 1 (2013): Nexus Kedokteran Klinik
Publisher : Fakultas Kedokteran Universitas Sebelas Maret Surakarta

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Abstract

Background: Inhalative anesthesia with isoflurane and sevoflurane are known to lower the oxygen saturation in patients. Both of these agents reduce the ventilation response to hypoxia. The aim of this study was to compare the effect of giving inhaled anesthetics isoflurane and sevoflurane to changes in oxygen saturation. Methods: This study was an observational analytic study with cross-sectional approach. The study was conducted at the Central Installation of Surgery dr. Moewardi Hospital. Samples were taken by consecutive sampling. There were two groups in this study, the first group received isoflurane anesthesia, the other group received sevoflurane anesthesia. Changing of oxygen saturation during operation was observed for two groups used bedside monitor. The data which have been collected analyzed using the Mann Whitney test and Pearson correlation test. Results: This study revealed a decrease in oxygen saturation for both groups in the induction phase (sevoflurane = 97.42 0.90; isoflurane = 97.00 0.75; p = 0.113). However, the oxygen saturation of isoflurane group was more fluctuating than sevoflurane group after inducton phase (p intubation = 0.001; p incision 5 = 0.117; p incision 10 = 0.001; p incision 15 = 0.048). The further analysis showed no statistically significant difference in oxygen saturation between the isoflurane and the sevoflurane groups (p = 0.113). Conclusions: There are no significant differences in changing of oxygen saturation between the isoflurane and sevoflurane anesthesia on the induction phase, 5 minutes and 15 minutes after incision. Anesthesia with sevoflurane in oxygen saturation is more stable compared with isoflurane anesthesia on intubation phase until 15 minutes after incision. Keywords: inhalation anesthesia, sevoflurane, isoflurane, hemodynamic, oxygen saturation
Co-Authors Aprilia Kusuma Dewi Aulia Nurul Fatimah Chatarina Umbul Wahyuni Diffah Hanim Galuh Larasati Hari Kusnanto Heru Subaris Kasjono Khoiron M.H. Sudjito Manurung, Imelda Februati Ester Mulyo Hadi Sudjito Prabuwinoto Setiawan Prasetyo Catur Utomo Reni Wijayanti Risda Sari Rizka Fitri Ardiani Sri Budi Utami Sri Yatmi Mei Kristiani Sugiarto Sugiarto Sumardiyono Sumardiyono Sumardiyono Sumardiyono Titi Supriati Wiwik Setyaningsih Yodi Mahendradhata