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All Journal Jurnal Keperawatan dan Fisioterapi (JKF) IJOEP : International Journal of Ecophysiology Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Ririe Fachrina Malisie
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Agriculture, Biological Sciences & Forestry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Other

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Self-Perception of Co-Assistant Students Regarding The Covid-19 Pandemic Chairiza Muttaqien; Putri Chairani Eyanoer; Ririe Fachrina Malisie; Hemma Yulfi
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 3 No. 2 (2021): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (542.746 KB) | DOI: 10.32734/jetromi.v3i2.5826

Abstract

Background: At the beginning of 2020, the world was shocked by a new type of coronavirus (SARS-CoV-2) whose disease was called Coronavirus disease 2019 (COVID-19). The research aims to determine the self-perception of Co-Assistant students regarding the COVID-19 pandemic. Method: The study was designed cross-sectional, which was conducted via sharing online links. Respondents must Co-Assistant students from a medical faculty in Indonesia and participated in the questionnaire filling between June 2020 and October 2020. This research is a descriptive study with a cross-sectional approach and conducted using primary data (online questionnaire Results: One hundred forty-nine students (149) of Co-Assistant students from several medical faculties all over Indonesia met the inclusive criteria. The samples were dominated by female respondents at 103 students (69.1%), while the male respondent accounted for only 46 students (30.9%). The first year of the Co-Assistant program with 94 respondents (63.1%) followed by the second year of the Co-Assistant program with 55 respondents (36.9%). The highest mean score in the fear zone came from the "first year of Co-Assistant program" group and the highest mean score in the learning and growth zone came from the "second year of Co-Assistant program" group. Conclusion: The highest mean score in the fear zone came from the "first year of Co-Assistant program" group and the highest mean score in the learning and growth zone came from the "second year of Co-Assistant program" group.
The Etiologies of Pediatric Acute Respiratory Distress Syndrome (PARDS) in Patients Treated at The PICU of Haji Adam Malik Hospital Medan in 2017 – 2020 Dea Ayunda; Ririe Fachrina Malisie; Ahmad Yapiz Hasby
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 4 No. 1 (2022): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (809.706 KB) | DOI: 10.32734/jetromi.v4i1.8016

Abstract

Background. Pediatric Acute Respiratory Distress Syndrome (PARDS) is considered to occur due to direct lung injury and indirect lung injury. The research aims to describe the causes of PARDS in patients treated at the Pediatric Intensive Care Unit (PICU) of Haji Adam Malik Hospital Medan in 2017-2020. Method. This type of research is a retrospective descriptive study with a cross-sectional study design uses secondary data in the form of medical records. The population of this study were all PICU patients aged 1 month – 18 years at Haji Adam Malik Hospital Medan in 2017-2020 using consecutive sampling technique. Results. Of the 100 PICU patients, there were 55 male patients with the most age group was <12 months. The most common mode of ventilation used is 80 invasive mechanical ventilation and duration of ventilation used has a mean value of 17.72 days. A mean value of Length of stay (LOS) patient was 25.47 days. Based on the Oxygenation Index (OI), of the 80 patients with invasive mechanical ventilation, most patients were 57 at risk PARDS, meanwhile, based on Oxygen Saturation Index (OSI) categories, of the 20 patients with non-invasive mechanical ventilation, most patients were 15 at risk PARDS. Most caused by indirect lung injury, namely 51 (51%), direct lung injury 47 (47%), and due to complications of using a ventilator as much as 2 (2%). Conclusion. The most common direct lung injury factor is the primary pulmonary infection, aspiration, trauma, and other factors. The most common indirect lung injury factor is sepsis, then central nervous system (CNS) disorders, postoperatively, and other factors.
Plasma Sirt-1 Level in Various Frailty Degree in Elderly Outpatients at Prof. Chairudin P. Lubis Hospital, Medan Fadhilah Hayati; Dedi Ardinata; Nuraiza Meutia; Ririe Fachrina Malisie; Muhammad Ichwan
International Journal of Ecophysiology Vol. 5 No. 2 (2023): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v5i2.13681

Abstract

Frailty is a physical aging syndrome characterized by health vulnerability. Diagnosis is established incorrectly based on three or more of the five criteria: weakness, decreased walking speed, fatigue, decreased physical activity, and weight loss. Sirtuin 1 plays a role in weakness, particularly in the elderly, acting as a protective factor during weakness, and its activation could provide a novel therapeutic approach. However, research in this area is still very limited. A cross-sectional method with observation or measurement of study subjects was employed in this research, involving a total of 118 elderly subjects selected through non-probability sampling. Pearson correlation test indicates a relationship between the polymorphism genotype (rs2273773) in the SIRT1 gene and the frailty scale (p-value < 0.05), while no relationship was found between plasma SIRT1 levels and the frailty scale (p-value > 0.05). Furthermore, the F-test reveals a significant simultaneous relationship between the polymorphism genotype (rs2273773) and plasma SIRT1 levels with frailty (p-value < 0.05).
DNMT1 Level as Biomarker for Early Detection of Nasopharyngeal Carcinoma Raudah Putri Syari; Zulham Yamamoto; Farhat; Sry Suryani Widjaja; Ririe Fachrina Malisie
JURNAL KEPERAWATAN DAN FISIOTERAPI (JKF) Vol. 8 No. 1 (2025): Jurnal Keperawatan dan Fisioterapi (JKF)
Publisher : Fakultas Keperawatan dan Fisioterapi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/qwakjv41

Abstract

Introduction: Nasopharyngeal carcinoma (NPC) is a malignant disease often diagnosed at an advanced stage. Early detection of NPC is necessary to reduce morbidity and mortality of this disease. To date, early detection methods for NPC still have limitations, especially in terms of positive predictive value. Identification of DNA methylation abnormalities has been studied for its role as a marker for early detection of NPC. Objective: This review describes the potential of DNMT1, an enzyme involved in DNA methylation, as a biomarker for early detection of NPC. Methods: We conducted a literature search using PubMed and Google Scholar databases. The keywords used were "nasopharyngeal carcinoma AND DNMT1", nasopharyngeal carcinoma AND early detection, "nasopharyngeal carcinoma AND screening", nasopharyngeal carcinoma OR DNMT1, “DNMT1 OR Carcinoma”, nasopharyngeal carcinoma OR screening, and nasopharyngeal carcinoma OR early detection. Results: Increased DNMT1 expression is associated with global hypermethylation which is part of the early pathogenesis of NPC. LMP1, as an oncoprotein released by EBV, increases DNMT1 expression and activity. Conclusion: High DNMT1 expression in NPC indicates its potential as an early detection method for NPC.
Co-Authors Ahmad Yapiz Hasby Ardinata, Dedi - Chairiza Muttaqien Dea Ayunda Dina Keumala Sari Fadhilah Hayati Farhat Hemma Yulfi M. Ichwan Muhammad Ichwan Nuraiza Meutia Putri Chairani Eyanoer, Putri Chairani Raudah Putri Syari Widjaja, Sry Suryani Yamamoto, Zulham Yulia Putri Yunita Sari Pane