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Improved basic life support skills and patient transportation at ambulance drivers in Medan Tuntung and Medan Sunggal area to improve patient safety Yetty Machrina; Siregar, Kamal Basri; Nuraiza Meutia; Gema Nazri Yanni; Yunita Sari Pane
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 2 (2019): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

The technique of providing basic and quick life support (BHD) and transportation to patients with cardiac and pulmonary arrest can save a patient's life. An ambulance driver as one of the ambulance personnel should be equipped with the two forms of skills above. The aim of community service is to increase the capacity of ambulance drivers in terms of providing basic life support skills and patient transportation to improve patient safety. This training was held in September 2019, at the H. Adam Malik General Hospital Training Center Installation Medan, with 24 participants. The training is carried out with 2 methods, namely exposure to BHD theory and BHD skills training. The knowledge and skills of participants before and after the training were assessed. Pre and post assessment results were analyzed using paired t-test with a significance level of p <0.05 Ambulance drivers in the Medan Tuntung and Medan Sunggal area are mostly over 30 years old, with most working as ambulance drivers for more than 5 years. The most recent level of education is high school graduation or equivalent. The results of statistical analysis using paired t-test, obtained a significant difference in the knowledge of ambulance drivers about basic life support theory before and after training (p = 0.000). Likewise, ambulance driver skills in providing basic life support for adult patients, infants and children were significantly different before and after training (p = 0.000). Training in basic life support skills and patient transportation can increase the capacity of ambulance drivers in providing basic life support..

Melanocortin-4 Receptors (MC4R) Liza Arieska Saiful; Nuraiza Meutia
AVERROUS: Jurnal Kedokteran dan Kesehatan Malikussaleh Averrous, Vol.9 No.1 Mei 2023
Publisher : Fakultas Kedokteran Universitas Malikussaleh

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29103/averrous.v9i1.10935

Melanocortin 4 Receptors (MC4R) merupakan turunan senyawa G protein coupled-receptors (GPCRs). MC4R berperan dalam homeostasis energi, fungsi kardiovaskular, dan sistem reproduksi. Gen MC4R ini menyandi sekitar 332 asam amino dan terkespresi pada hipotalamus. MC4R salah satu protein transmembran dengan memiliki tujuh subtipe protein. Melanocortin-pathway berhubungan dengan pro-opiomelanocortin (POMC) dalam aktivasi leptin sehingga meningkatkan dan menurunkan nafsu makan. Mutasi yang ditemukan pada MC4R berbanding lurus dengan kejadian obesitas. Mutasi yang terjadi bisa karena munculnya defek pada struktur MC4R, ekspresi pada permukaan membran sel, ikatan dengan ligan dan jalur sinyal. POMC akan mengaktivasi atau inaktivasi MC4R sesuai dengan kebutuhan energi tubuh. MC4R akan berikatan dengan agonis α-MSH atau β-MSH dan antagonis AgRP. Kesimpulannya, pengaturan MC4R dalam tubuh meliputi fungsi kardiovaskular, aktivitas insulin dan sistem reproduksi. Sehingga saat ini menjadi target sebagai terapi antiobesitas.

Improving knowledge and attitude to tackle COVID-19 transmission in a health care facility of North Sumatra’s village Evita Mayasari; Lokot D. Lubis; Nuraiza Meutia; Cut A. Adella; Eka R. Megawati
Journal of Community Service and Empowerment Vol. 4 No. 2 (2023): August
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/jcse.v4i2.25205

COVID-19 hits Indonesia with massive social restrictions in many aspects of life. In some Indonesian rural areas, information related to the pandemic through online platforms and social media is accessible. However, most of the information is inaccurate. Improving individual knowledge is crucial to support the government’s campaign for COVID-19 prevention. This cross-sectional, pretest-posttest study aims to evaluate the knowledge and attitude of health personnel toward COVID-19 prevention in a primary healthcare facility in a rural area of North Sumatra. All twenty-two health personnel who worked in the hospital during the study were asked to fill in a two-sectioned questionnaire. The first section contained questions related to knowledge, and the second section was related to attitude toward COVID-19. Following the educational activity, each health personnel filled in the same questionnaire again. We analyzed the data statistically using two-way ANOVA (p<0.05, 95% CI). There were increases in knowledge (p < 0.001) and attitude (p = 0.0002) of the health personnel after the educational activity. Educational activity improves health personnel’s knowledge and attitude regarding COVID-19 prevention.

PLASMA β-SECRETASE1 (BACE1) LEVELS AS MARKER OF COGNITIVE FUNCTION DECLINE IN ELDERLY Syahfira A Syahna; Muhammad Ichwan; Nuraiza Meutia; Jelita Siregar; Zulham Yamamoto
International Journal of Ecophysiology Vol. 5 No. 2 (2023): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v5i2.14129

BACE1 which forms amyloid plaques consisting of amyloid β peptides is a typical neuropathological lesion in the brain of Alzheimer's disease. Many studies have shown that β-amyloid is central to the pathophysiology of Alzheimer's disease and may play an early role in neurodegenerative disorders. The BACE1 enzyme forms amyloid β plaques. The BACE1 protein is detectable in plasma and its levels are significantly increased in patients with mild cognitive impairment and future Alzheimer's. This Aβ peptide accumulates into senile plaques causing the characteristics of Alzheimer's disease, can cause neuronal death and cognitive decline

Improved basic life support skills and patient transportation at ambulance drivers in Medan Tuntung and Medan Sunggal area to improve patient safety Yetty Machrina; Kamal Basri Siregar; Nuraiza Meutia; Gema Nazri Yanni; Yunita Sari Pane
ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat Vol. 4 No. 2 (2019): ABDIMAS TALENTA: Jurnal Pengabdian Kepada Masyarakat
Publisher : Talenta Publisher

The technique of providing basic and quick life support (BHD) and transportation to patients with cardiac and pulmonary arrest can save a patient's life. An ambulance driver as one of the ambulance personnel should be equipped with the two forms of skills above. The aim of community service is to increase the capacity of ambulance drivers in terms of providing basic life support skills and patient transportation to improve patient safety. This training was held in September 2019, at the H. Adam Malik General Hospital Training Center Installation Medan, with 24 participants. The training is carried out with 2 methods, namely exposure to BHD theory and BHD skills training. The knowledge and skills of participants before and after the training were assessed. Pre and post assessment results were analyzed using paired t-test with a significance level of p <0.05 Ambulance drivers in the Medan Tuntung and Medan Sunggal area are mostly over 30 years old, with most working as ambulance drivers for more than 5 years. The most recent level of education is high school graduation or equivalent. The results of statistical analysis using paired t-test, obtained a significant difference in the knowledge of ambulance drivers about basic life support theory before and after training (p = 0.000). Likewise, ambulance driver skills in providing basic life support for adult patients, infants and children were significantly different before and after training (p = 0.000). Training in basic life support skills and patient transportation can increase the capacity of ambulance drivers in providing basic life support..

The Relationship between Stress and Incidence of Sleep Disorder among Students at the Faculty of Medicine Universitas Sumatera Utara Ibnati Amira Hamdi Hamdi; Nuraiza Meutia; Sabri Ibrahim; Tasrif Hamdi
Sumatera Medical Journal Vol. 5 No. 2 (2022): Sumatera Medical Journal (SUMEJ)
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/sumej.v5i2.7988

Abstract. Stress is a non-specific response of the body to any form of changes. Stress is generally considered synonymous with distress. Long study duration and high academic achievement targets have the potential to cause stress in medical students. Prolonged stress can cause sleep disturbances in a person. Sleep disorders are a group of conditions that can disrupt sleep patterns. Objective. The purpose of this study was to determine the effect of stress on sleep disorders in undergraduate students at the Faculty of Medicine, Universitas Sumatera Utara. Methods. This research is an analytic study with a cross-sectional design. Respondents are undergraduate students at the Faculty of Medicine, University of North Sumatra, class of 2018-2021. Data was obtained through a questionnaire instrument. Results. Of the 103 respondents, 58 (56.3%) reported experiencing stressful events with sleep disturbances. Conclusion. There was a significant relationship (P = 0.047) between stress and sleep disorders in students at the Faculty of Medicine, University of North Sumatra. In majority, the type of their sleep disorder are nightmares.

Plasma Sirt-1 Level in Various Frailty Degree in Elderly Outpatients at Prof. Chairudin P. Lubis Hospital, Medan Fadhilah Hayati; Dedi Ardinata; Nuraiza Meutia; Ririe Fachrina Malisie; Muhammad Ichwan
International Journal of Ecophysiology Vol. 5 No. 2 (2023): International Journal of Ecophysiology
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijoep.v5i2.13681

Frailty is a physical aging syndrome characterized by health vulnerability. Diagnosis is established incorrectly based on three or more of the five criteria: weakness, decreased walking speed, fatigue, decreased physical activity, and weight loss. Sirtuin 1 plays a role in weakness, particularly in the elderly, acting as a protective factor during weakness, and its activation could provide a novel therapeutic approach. However, research in this area is still very limited. A cross-sectional method with observation or measurement of study subjects was employed in this research, involving a total of 118 elderly subjects selected through non-probability sampling. Pearson correlation test indicates a relationship between the polymorphism genotype (rs2273773) in the SIRT1 gene and the frailty scale (p-value < 0.05), while no relationship was found between plasma SIRT1 levels and the frailty scale (p-value > 0.05). Furthermore, the F-test reveals a significant simultaneous relationship between the polymorphism genotype (rs2273773) and plasma SIRT1 levels with frailty (p-value < 0.05).

Systematic Review Of Relationship Stunting With Intelligence Of Elementary School Children Alfira, Alfira; Keumalasari, Dina; Meutia, Nuraiza; Wahyuni, Arlinda Sari; Martony, Oslida; Harahap, Armansyah Maulana
BEST Journal (Biology Education, Sains and Technology) Vol 7, No 1 (2024): Juni 2024
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v7i1.9025

Satu dari tiga anak di Indonesia mengalami stunting. Stunting dapat berdampak pada perkembangan motorik dan verbal, meningkatkan penyakit degeneratif, morbiditas dan mortalitas. Selain itu, stunting akan menyebabkan pertumbuhan dan perkembangan sel neuron terhambat, sehingga mempengaruhi perkembangan kognitif pada anak. Dampak yang ditimbulkan oleh stunting terhadap perkembangan kognitif pada anak berbeda-beda, oleh karena itu penelitian ini bertujuan untuk mengetahui apa saja dampak stunting terhadap kemampuan kognitif pada anak. Metode yang digunakan adalah tinjauan literatur sistematis yang diambil dari jurnal nasional dan internasional. Berdasarkan hasil review, ditemukan bahwa stunting memiliki implikasi biologis terhadap perkembangan otak dan neurologis yang diterjemahkan ke dalam penurunan nilai kognitif. Stunting yang parah dengan Z-skor -3SD dari indeks panjang badan menurut umur atau tinggi badan menurut umur anak memiliki dampak negatif terhadap tumbuh kembang anak. Selain itu, anak yang mengalami stunting pada 2 tahun pertama kehidupannya cenderung memiliki IQ non-verbal di bawah 89 dan IQ 4,57 kali lebih rendah dari IQ anak yang tidak mengalami stunting. Disimpulkan bahwa stunting memberikan pengaruh negatif terhadap kemampuan kognitif anak yang berdampak pada prestasi belajar.

Systematic Review Of Relationship Stunting With Intelligence Of Elementary School Children Alfira, Alfira; Keumalasari, Dina; Meutia, Nuraiza; Wahyuni, Arlinda Sari; Martony, Oslida; Harahap, Armansyah Maulana
BEST Journal (Biology Education, Sains and Technology) Vol 7, No 1 (2024): Juni 2024
Publisher : Program Studi Pendidikan Biologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/best.v7i1.9025

Satu dari tiga anak di Indonesia mengalami stunting. Stunting dapat berdampak pada perkembangan motorik dan verbal, meningkatkan penyakit degeneratif, morbiditas dan mortalitas. Selain itu, stunting akan menyebabkan pertumbuhan dan perkembangan sel neuron terhambat, sehingga mempengaruhi perkembangan kognitif pada anak. Dampak yang ditimbulkan oleh stunting terhadap perkembangan kognitif pada anak berbeda-beda, oleh karena itu penelitian ini bertujuan untuk mengetahui apa saja dampak stunting terhadap kemampuan kognitif pada anak. Metode yang digunakan adalah tinjauan literatur sistematis yang diambil dari jurnal nasional dan internasional. Berdasarkan hasil review, ditemukan bahwa stunting memiliki implikasi biologis terhadap perkembangan otak dan neurologis yang diterjemahkan ke dalam penurunan nilai kognitif. Stunting yang parah dengan Z-skor -3SD dari indeks panjang badan menurut umur atau tinggi badan menurut umur anak memiliki dampak negatif terhadap tumbuh kembang anak. Selain itu, anak yang mengalami stunting pada 2 tahun pertama kehidupannya cenderung memiliki IQ non-verbal di bawah 89 dan IQ 4,57 kali lebih rendah dari IQ anak yang tidak mengalami stunting. Disimpulkan bahwa stunting memberikan pengaruh negatif terhadap kemampuan kognitif anak yang berdampak pada prestasi belajar.

HUBUNGAN FAKTOR-FAKTOR GAYA HIDUP DENGAN TEKANAN DARAH PADA PENDERITA HIPERTENSI Musliana; Meutia, Nuraiza
Ibnu Sina: Jurnal Kedokteran dan Kesehatan - Fakultas Kedokteran Universitas Islam Sumatera Utara Vol. 21 No. 1 (2022): Januari 2022
Publisher : Faculty of Medicine Universitas Islam Sumatera Utara

Perubahan gaya hidup didalam masyarakat, seperti kebiasaan makan berlebihan, terlalu banyak aktivitas, banyak merokok, dan kurang istirahat menyebabkan meningkatnya prevalensi penderita hipertensi. Di Indonesia prevalensi hipertensi mencapai 25,8%. Hipertensi tidak dapat disembuhkan, namun penderita hipertensi dapat memiliki kualitas hidup yang baik dengan melakukan perubahan gaya hidup. Oleh karena itu penelitian ini dilakukan untuk mengetahui hubungan faktor-faktor gaya hidup berupa kebiasaan merokok, konsumsi kafein dan kualitas tidur dengan tekanan darah pada penderita hipertensi. Penelitian deskriptif analitik dengan desain cross sectional menggunakan data primer berupa kuesioner dan data sekunder dari rekam medik dengan jumlah responden 116 responden (79 perempuan dan 37 laki-laki) yang terdata sebagai pasien di Puskesmas Padang Bulan dan Puskesmas Teladan. Terdapat 74,1% responden dengan tekanan darah tidak terkontrol. Penelitian ini menunjukkan bahwa kebiasaan merokok didapat nilai (p) = 0,923. Kebiasaan konsumsi Kafein didapat nilai (p) = 0,0025. Kualitas Tidur didapatkan nilai (p) = 0,018. Kesimpulan : Kualitas tidur dan konsumsi kafein berhubungan dengan tidak terkontrolnya tekanan darah pada penderita hipertensi. Namun, pada kebiasaan merokok tidak didapatkan adanya hubungan dengan peningkatan tekanan darah pada penderita hipertensi.

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