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Journal : Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan

Analisis Kadar Logam Berat Timbal (PB) pada Makanan Kaleng Daging Giling Berbagai Merk Panji Ratih Suci; Muh. Latif 'Alim; Sulfika Oriza Nova Sativa
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 2 (2024): March : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i2.276

Abstract

Along with increasingly rapid technological developments in our country, the number of existing industries is increasing. Apart from producing useful products, this industry also produces waste. The waste produced contains a lot of heavy metals, one of which is the heavy metal lead. If the lead metal in the waste receives little treatment, this can cause pollution in the environment, even though this waste is present in small quantities, the lead condition is unstable and if it accumulates in the body, it can ultimately trigger cancer cells (carcinogenic) which can be dangerous for health. . In this research, adsorption of PB2+ ions was carried out on canned ground meat, where heavy metal contamination occurred in the ground meat. This research aims to determine the effectiveness of the absorption of heavy metals (Pb) contained in ground beef and their characteristics. The uptake of PB2+ ions in ground beef, measuring the concentration of PB2+ ions before and after receiving treatment, was carried out using an instrument, namely AAS, at a wavelength of 217nm. The research results showed that the effectiveness of ground beef in absorbing PB2+ ions in canned food was as high as brand a: 0.023; brand b: 0.009; brand c: 0.006
Efektivitas Sabun Cuci Tangan Ekstrak Daun Afrika ( Vernonia amygdalina Del.) Terhadap Bakteri Escherichia coli Panji Ratih Suci; Cikra Ikhda Nur H.S; Anita Candra Ningtyas; Annisa Lailatul Maghfiroh
OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 3 (2024): May : OBAT: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : Asosiasi Riset Ilmu Kesehatan Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/obat.v2i3.364

Abstract

African leaf plants (Vernonia amygdalina Del.) is one of tradisional medicine and has pharmacological contain secondary metabolite such as Flavonoids, Saponin, Tanin and Alkaloid. This study aimed to determine the antibacterial activity of African leaf extract (Vernonia amygdalina Del.) in handsoap formulation on the growth of Escherichia coli. African left extract was obtained from maceration process with ethanol and phytochrmical screening was carried out.This study uses concentration of 0,5%, 1% and 2%. Antibacterial activity testing using scratch and disc diffusion methods. Tis study also evaluated the pyshical quality of the preparation which included organoleptic observation, homogeneity test, high foam test and antibacterial activity test. Antibacterial activity testing using scratch and disc disfusion methods. African pyctochemical screening was carried out. The result showed that the percentage of African leaf extract yield was 24,958%. The pH test gets a pH of 10-11 and 5-6 cm foam height test. The highest concentration of positive control of preparation containing alcohol (Dettol) with an average number og 4,72 mm ± 1,45 mm. Liquid soap preparation 1% with a diameter of inhibition of 3,93 mm ± 1,97 mm. The result of this study inhibit the growth of Eshcherichia coli bacteria.