Claim Missing Document
Check
Articles

Found 2 Documents
Search
Journal : Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan

UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN MARKISA KUNING (Passiflora edulis var. flavicarpa degener) PADA BAKTERI Escherchia coli Panji Ratih Suci; Latiful Fauziyah; Pramudita Putra Dwi Ramadhan
Jurnal Ilmiah Manuntung Vol 9 No 1 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i1.658

Abstract

Diarrhea is a condition in which the body loses most of its fluids and electrolytes caused by defecating three or more times a day with a thick, fluid consistency. The purpose of this study was to determine the antibacterial activity of the ethanolic extract of passion fruit (Passiflora edulis var. flavicarpa Degener) to inhibit the growth of Escherichia coli bacteria. The extraction method used maceration with 70% ethanol solvent and then continued with the antibacterial activity test at a concentration of 10%, 20%, and 30% using the disk diffusion method with 3x replication. The results of the antibacterial activity test were analyzed by the method of one-way ANOVA followed by a post hoc test (Tukey). The results of data analysis showed that the ethanolic extract of yellow passion fruit leaves had activity to inhibit the growth of Escherichia coli bacteria with the average diameter of the inhibition zone at a concentration of 10% (3.85 mm), at a concentration of 20% (6.61 mm), at a concentration of 30% (11.69 mm), and in the data analysis test, a value (sig 0.05) was obtained, which means that there are differences in the antibacterial activity of each concentration and positive control.
FORMULASI DAN UJI ANTIBAKTERI SEDIAAN SABUN MANDI CAIR EKSTRAK DAUN RAMBAI PADI (Sonneratia caseolaris L.) TERHADAP Staphylococcus aureus Ghina, Adhila; Fitri Handayani; Achmad Kadri Ansyori; Panji Ratih Suci; Erna Fitriany
Jurnal Ilmiah Manuntung Vol 10 No 1 (2024): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v10i1.784

Abstract

Rampai padi (Sonneratia caseolaris L.) grows along the coast Mahakam River in Samarinda. It was identified to contain flavonoids with, high potential as antioxidants and antibacterials. Previous studies have explored the content, pharmacological activity, and development of preparations. This study aimed to formulate the ethanol extract of rambai padi leaves (EEDRP) in liquid bath soap and to determine its pharmacological activity as an antibacterial (Staphylococcus aureus). The sample used is EEDRP which is formulated in liquid bath soap in three formulations, A (5%), B (10%), and C (15%). The results of the phytochemical screening of EEDRP contained flavonoids, phenolics, tannins, saponins, and steroids. The EEDRP can be formulated into a liquid bath soap that is homogeneous, has a characteristic odor, and is blackish-brown to dark green-gray. The pH test results on the 1st, 3rd, and 7th day met the quality requirements, namely pH 4-10, the foam height test which met the foam height requirements of 1 - 10 cm. The total plate number test result was 0 colonies/g. The antibacterial activity of EEDRP liquid soap in formula A (5%) had an inhibition zone of 4.11 mm, formula B (10%) of 4.17 mm, and formula C (15%) of 6.38 mm.