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Nasution, Pandapotan
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Medicine & Pharmacology

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FORMULASI EKSTRAK TONGKOL JAGUNG (Zea mays L.) SEBAGAI TABIR SURYA DALAM SEDIAAN LOTION UNTUK WAJAH Silitonga, Maringan; Nasution, Pandapotan; Thaib, Cut Masyithah; Haloho, Mei Revolinda
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Corn cobs (Zea mays L.) can be used as sunscreen because it contains phenolic compounds. The purpose of this study was to determine the characteristics of the physical and chemical properties of sunscreen lotion preparations of corncob ethanol extract and the formula and concentration that had the highest effectiveness in the value of Sun Protection Factor (SPF). The lotion was chosen because it is a topical preparation that is often used by the community. Corn cob powder was extracted by the maceration method. The results were formulated with extract concentrations, formulation I (5%), formulation II (10%), and formulation III (15%). The three formulas were tested for organoleptic, pH test, homogeneity, and lotion type. The resulting data were analyzed descriptively. The results showed that all formulas with varying concentrations of extracts had good physicochemical characteristics during storage based on the results of pH, homogeneity, organoleptic, and emulsion-type tests. Corncob ethanol extract sunscreen lotion in Formula 1 (5%) has an SPF value of 2 (UV-A rays) and an SPF value of 7 (UV-B rays). Formula 2 (10%) has an SPF value of 2,3 (UV-A rays) and has an SPF value of 9 (UV-B rays) and Formula 3 (15%) has an SPF value of 3 (UV-A rays) and has a value of SPF 12 (UV-B Rays).
PEMERIKSAAN JAMUR PADA ROTI ISI KACANG HIJAU YANG DIPERJUALBELIKAN DI PASAR SEI SIKAMBING MEDAN Sinaga, Eka Margaretha; Nasution, Pandapotan; Maimunah, Siti; Yanti, Surfin Putri
Jurnal Farmanesia Vol 5 No 1 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v5i1.2727

Abstract

Green-bean filling bread is made from wheat flour and water and fermented with yeast. The presence of carbohydrates and sugar in bread causes mold to grow. This examination aims to determine the presence or absence of fungus on green bean sandwiches according to the SNI standard with no more than 104 microbial ingredients. The medium used in this examination is Potato Dextrose Agar (PDA) which has been added with 0.1% chloramphenicol. This examination uses an experimental method (parametric experiment). The sample in this examination is green bean stuffed bread traded in the Sei Sikambing market in Medan, the number of samples examined is 4 types from 2 shophouses in the Sei Sikambing market, Medan in 2015. The results of the examination showed the presence of fungal growth in all samples so the sample does not meet the requirements of SNI. To consume bread, you should pay attention to the condition of the bread at the time of buying.
PERBANDINGAN UJI AKTIVITAS ANTIDIABETES EKSTRAK DAUN LIDAH BUAYA DAN LIDAH MERTUA PADA MENCIT PUTIH JANTAN Sianipar, Artha Yuliana; Supartiningsih, Supartiningsih; Nasution, Pandapotan; Maimunah, Siti; Gloria, Rifka
Jurnal Farmanesia Vol 5 No 2 (2018): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v5i2.2734

Abstract

Diabetes mellitus (DM) is a disease whose prevalence is increasing from year to year. This increase was accompanied by an increase in the cost of treatment and the number of complications. The use of traditional medicine is an alternative for the community to control blood sugar levels (KGD). Considering that synthetic drugs have various side effects, one of the medicinal plants used as traditional medicine is aloe vera leaf and mother-in-law's tongue leaf which contain flavonoid compounds, alkaloids, tannins, saponins, and steroids/triterpenoids. The purpose of this study was to determine the antidiabetic activity of aloe vera leaf extract and mother-in-law's tongue and to compare the activities of the two. The results of the analysis of the glucose tolerance ANOVA test showed a significant difference in the percentage reduction at 60, 90, and 120 minutes for all treatment preparations. The alloxan induction test showed a significant difference in the percentage decrease from days 3, 5, 7, 9, 11, 13, and 15. Based on these results, it can be concluded that Aloe Vera Leaf Ethanol Extract (EEDLB) and LidahMertua Leaf Ethanol Extract (EEDLM) with each dose of 150 and 200 mg/kg BW and the combination of the two gave antidiabetic activity against mice as well as differences in effectiveness between samples of aloe vera leaf and LidahMertua leaf as well as a single dose with a combination.
PENETAPAN KADAR NATRIUM PADA BUAH PISANG EMAS (Musa acuminata Colla.) SECARA SPEKTROFOTOMETRI SERAPAN ATOM Simanjuntak, Nelson; Marpaung, Jon Kenedy; Nasution, Pandapotan; Pratiwi, Tiara
Jurnal Farmanesia Vol 7 No 1 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i1.2759

Abstract

Bananas are the most consumed fruit by the people of Indonesia. This fruit has many health benefits including improving digestion, treating anemia, healthy bones, and improving nerve function. The nutritional content contained in bananas is carbohydrates, sugar, dietary fiber, fat, protein, vitamins, and minerals such as sodium, calcium, magnesium, phosphorus, potassium, and zinc. This study aims to determine the sodium content in golden bananas. The assay was carried out using an air-acetylene flame atomic absorption spectrophotometer. Quantitative analysis of sodium was carried out at a wavelength of 589.6 nm. The results of the study concluded that the sodium content of golden bananas was 1.8647 mg/100g. The results of the relative standard deviation test are 15% and have good precision because the results obtained for analytes with levels of parts per million are not more than 16% (Harmita, 2004).
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAUN LEGUNDI (Vitextrifolia L.) TERHADAP PERTUMBUHAN Staphylococcus epidermidis Marpaung, Jon Kenedy; Sitorus, Panal; Nasution, Pandapotan; Yanti, Roma Devina
Jurnal Farmanesia Vol 7 No 2 (2020): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v7i2.2770

Abstract

Legundi leaves (Vitextrifolia L.) contain flavonoid compounds, alkaloids and saponins, tannins, steroids/triterpenoidsthatact as antiseptic substancesandaid in the wound healing process. Staphylococcusepidermidis (Gram positive) is a mild skin infection-causing bacteria that accompanies the formation of abscesses. As for the purpose of this study To know the absence of antibacterial activity from concentrations of 10%, 15%, 20%, 25% legundileaf extractagainst Staphylococcus epidermid is bacteria and know the effective concentration of legunleaf extract in in hibiting the growth of Staphylococcus epidermidis bacteria. This research methoduses experimental methods and legundileaf extract with concentrations of 10%, 15%, 20%, 25%. The resultsshowedthatconcentrationsof 10%, 15%, 20%, 25% of legundileaf ethanol extract had antibacterial activity against the growth of Staphylococcus epidermidisindicated with a blockable zone diameter of 8 mm, 8.84 mm, 9.84 mm, 10.54 mm, respectively. Base dont here search that has beendone can be concluded that legundileaf extractcan inhibit the growth of bacteria Staphylococcus epidermidis, because around the discpaperthere is a clear zone that indicates the absence of bacterial growth.
PEMBUATAN PATI DARI RIMPANG LENGKUAS, TEMULAWAK, TEMUKUNCI SERTA KARAKTERISASINYA Nasution, Pandapotan; Suharyanisa, Suharyanisa; Situmorang, Manahan; Manihuruk, Nurpita Putri
Jurnal Farmanesia Vol 8 No 2 (2021): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v8i2.2791

Abstract

The rhizome is part of the plant for food reserves, including storing carbohydrates (starch), therefore rhizomes of Galangal, Curcuma, Fingerroot rhizome can be used as a source of starch. This study used an exploratory method which included isolation of starch from Galangal, Curcuma, Fingerroot Rhizome, macroscopic examination, microscopic examination, sample collection, sample processing, and examination of the characterization of starch. The results of starch characterization obtained yields for Galangal starch 2.6%, Curcuma starch 5.4%, Fingerroot rhizome starch 4.1%; determination of total ash content for Galangal starch 1.4%; Curcuma starch 2.0%, Fingerroot rhizome starch 1.0%; determination of drying shrinkage for 1.8% Galangal starch, 2.4% Curcuma starch, 3.2% Fingerroot rhizome starch; determination of acid-insoluble ash content for 0.6% Galangal starch, 0.7% Curcuma starch, 0.7%Fingerroot rhizome starch.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK BUNGA KECOMBRANG (Etlingera elatior) TERHADAP PERTUMBUHAN BAKTERI Salmonella thypi Nasution, Pandapotan; Marpaung, Jon Kenedy; Suharyanisa, Suharyanisa; Sitanggang, Rolastri
Jurnal Farmanesia Vol 9 No 1 (2022): Jurnal Farmanesia
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51544/jf.v9i1.3430

Abstract

Kecombrang (Etlingera elatior) is a type of spice that has long been known and used by humans as medicine. Kecombrang flower parts contain several chemical compounds, namely: alkaloids, flavonoids, and saponins. In addition, kecombrang flowers can also inhibit the growth of Salmonella typhi bacteria. This study aims to determine the concentration of ethanolic extract of kecombrang flower (Etlingera elatior) which is effective in inhibiting the growth of Salmonella typhi bacteria. The research sample was Kecombrang Flowers purchased at the Tarutung traditional market. This research was carried out experimentally including sampling, drying simplicia, maceration using 70% ethanol solvent, making extracts made using a rotary evaporator, and testing the antibacterial activity of kecombrang flowers using the disc diffusion method. Data analysis was conducted to see the effect of kecombrang flower ethanol extract on the activity of Salmonella typhi bacteria. The results of the study found that the results of phytochemical screening showed simplicia and ethanol extract of kecombrang flower leaves contained alkaloids, flavonoids, and saponins. While the results of the antibacterial activity test of the ethanolic extract of kecombrang flower leaves have antibacterial properties against Salmonella typhi at extract concentrations of 45%, 50%, 55%, and 60% with inhibition zone diameters of 9.4 mm, 12.2 mm, 14.8 mm, respectively. , 16.3mm. The most effective concentration of ethanol extract to inhibit the growth of Salmonella typhi was at a concentration of 60% with a larger inhibition zone diameter of 16.3 mm.
Co-Authors Eka Margareta Sinaga Gloria, Rifka Haloho, Mei Revolinda Manihuruk, Nurpita Putri Marpaung, Jon Kenedy Nelson Simanjuntak Sianipar, Artha Yuliana Silitonga, Maringan Sitanggang, Rolastri Siti Maimunah Sitorus, Panal Situmorang, Manahan Suharyanisa Supartiningsih - - Thaib, Cut Masyithah Tiara Pratiwi, Tiara Yanti, Roma Devina Yanti, Surfin Putri