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All Journal Indonesian Journal of Obstetrics & Gynecology Science Jurnal EduHealth
Susiawaty, Susiawaty
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Health Professions Public Health Veterinary

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Hubungan antara Kadar Hepsidin dan Kadar Hemoglobin pada Kehamilan dengan Obesitas Ratnaningsih, Andi Sri; Sunarno, Isharyah; Madya, Fatmawati; Hamid, Firdaus; Irianta, Trika; Susiawaty, Susiawaty
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.583

Abstract

Tujuan: Untuk menilai kadar Hepsidin dan kadar hemoglobin menggunakan sampel darah dan selanjutnya dianalisis dengan metode ELISA.Metode: Penelitian ini merupakan kohort prospektif pada perempuan hamil dengan obesitas dan pembanding non-obesitas pada trimester pertama dan kedua di RSUP Dr. Wahidin Sudirohusodo dan Rumah Sakit Pendidikan Jejaring pada periode Januari - Agustus 2022.Hasil: Penelitian dilakukan terhadap 44 sampel yang terdiri atas 22 sampel kelompok ibu hamil dengan obesitas dan 22 sampel ibu hamil dengan IMT normal. Pada pasien obesitas tidak didapatkan korelasi antara kadar Hepsidin dan kadar hemoglobin di trimester pertama dengan nilai p=0.097 sedangkan pada trimester kedua terdapat korelasi dengan nilai p=0.028. Pada pasien non obesitas tidak didapatkan korelasi antara kadar Hepsidin dengan kadar hemoglobin nilai p=0.489 di trimester pertama dan nilai p=0.906 di trimester kedua.Kesimpulan: Peningkatan kadar Hepsidin dan anemia dapat ditemukan pada wanita obese yang sedang hamil, terutama pada trimester kedua.The Relationship Between Hepcidin Levels And Hemoglobin Levels In Pregnancy With ObesityAbstract Objective: To compare hepcidin levels and hemoglobin levels using blood samples and further analyzed with ELISA method.Method: This study is a prospective cohort of obese pregnant women and a non-obese comparator in the first and second trimesters at RSUP Dr. Wahidin Sudirohusodo Hospital and Networking Teaching Hospitals in the period January - August 2022.Results: The study was conducted on 44 samples consisting of 22 samples of obese pregnant women and 22 samples of pregnant women with normal BMI. In obese sample, there was no correlation between hepcidin levels and hemoglobin levels in the first trimester with a value of p=0.097 while in the second trimester there was a correlation with a value of p=0.028. In non-obese patients, there was no correlation between hepcidin levels and hemoglobin levels, p = 0.489 in the first trimester and p= 0.906 in the second trimester.Conclusion: Increased hepcidin levels and anemia can be found in obese women in the second trimester of pregnancy.Key words: Hepcidin, Obesity, Hemoglobin
Risk factors for gestational hypertension at RSIA Sitti Khadijah 1 year 2019-2022 Ainun Jariah Fahay; Fadli Ananda; Nur Fatimah Sirajuddin; M. Hamsah; Susiawaty, Susiawaty
Jurnal EduHealth Vol. 15 No. 01 (2024): Jurnal eduHealt, Edition January - March, 2024
Publisher : Sean Institute

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Abstract

Gestational hypertension (also called transient hypertension) is hypertension that occurs in pregnancy without proteinuria. This research was conducted at RSIA Khadijah Makassar 1 year 2019-2022, using a retrospective descriptive method, using total quota sampling that met the inclusion criteria. The number of samples obtained was 32 samples with the characteristics of gestational hypertension occurring most frequently at the age of 20-35 years, namely 26 (81.25%), with grand multigravida, namely 13 (40.6%), BMI >25 kg/m2 27 ( 84.4%), and in patients without a history of hypertension, namely 17 (53.12%). Based on statistical tests, it was found that there is a relationship between gravida and the incidence of gestational hypertension with a p-value of 0.083, which is smaller than 0.10, meaning that pregnant women with primigravida and grand multigravida have a 9.3 times higher risk of developing gestational hypertension than pregnant women. with multigravida, while age, BMI, and history of hypertension had no significant relationship to the incidence of gestational hypertension at RSIA Sitti Khadijah 1. .
Co-Authors Ainun Jariah Fahay Fadli Ananda Hamid, Firdaus M. Hamsah Madya, Fatmawati Nur Fatimah Sirajuddin Ratnaningsih, Andi Sri Sunarno, Isharyah Trika Irianta