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Obstetric Risk Factors and Anal Incontinence among Women with Previous History of Vaginal Delivery Nurdin, Azizah; Irianta, Trika; Tahir, Mardiah; Chalid, Maisuri T.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the obstetric risk factors of the analincontinence in mothers with previous history of vaginaldelivery.Methods: The was a case-control study conducted in the Obstetricsand Gynecology Department of Dr.Wahidin Sudirohusodo Hospital,Faculty of Medicine, Universitas Hasanuddin, Makassar, during theperiod of February 2015 through January 2016. The researchinstruments were used to evaluate obstetric risk factors and theanal incontinence was the self-administered questionnaire and FecalIncontinence Severity Index. The data were analyzed statisticallyusing the Chi-square test with the significant value of p<0.05.Results: A total of 300 subjects were recruited in this study. Theresearch results indicated that the parity of  3, the assisted vaginaldelivery history (vacuum extraction), and the prolong secondstage of labor had a significant correlation with the anal incontinencewith p value=0.026, OR (95% CI) = 1.8 (1.07-3.03), p=0.018with OR (95% CI) =3.65 (1.2-10.7) and p=0.006 with OR (95% CI)= 2.9 (1.2-6.7).The history of episiotomy and the delivery of thebaby  4000 gram had no correlation with the anal incontinence.Conclusion: Parity, vacuum delivery and prolong second stage oflabor have an association with anal incontinence among womenwho has history of vaginal delivery.Keywords: anal incontinence, obstetric risk factors, vaginal delivery

Tenascin-C is Strongly Expressed in the Anterior Vaginal Walls of Women with Pelvic Organ Prolapse Sulham, Risma N.; Irianta, Trika; Malinta, Umar
Indonesian Journal of Obstetrics and Gynecology Volume. 1, No. 4, October 2013
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objectives: To compare the expression of tenascin in the anterior vaginal wall in women with pelvic organ prolapse and without pelvic organ prolapse (POP). Method: This study was a cross sectional study. The study was conducted in RS Dr. Wahidin Sudirohusodo and other network hospitals of Obstetrics and Gynecology Department of Hasanuddin University, Makassar, from 1st January 2011 to 1st April 2012. This study assessed the expression of tenascin in 35 women with pelvic organ prolapse grade III and IV and the controls were 35 women without pelvic organ prolapse. Tenascin expression was assessed by immunohistochemical examination using tenascin antibody staining (mouse monoclonal antibody Novacastratenascin C, code NCLTenasC). Sampling was done by consecutive sampling. Data processed by the chi-square. The significance level used was 0.05. Result: The result of this research shows that with exception of history of bearing baby > 4000 gr weight (p=0.572); age, parity, menopausal status, and body mass index were significantly different between the group. This indicates that the variable does not affect the calculation of research data. While parity, menopausal status and body mass index (BMI), from an analysis of risk factors for POP were associated with increased intensity of tenascin is significant in postmenopausal status, and BMI > 25 (overweight) (p <0.05). Expression of tenascin in a sample of moderate (+ +) as many as 18 cases (51.5%) compared with controls expression of tenascin weaker (+) 25 cases (71.5%). Conclusion: Expression of tenascin robust anterior vaginal wall in women with POP and weak women without POP. Keywords: pelvic organ prolaps, risk factors, tenascin-C

Obstetric Risk Factors and Anal Incontinence among Women with Previous History of Vaginal Delivery Nurdin, Azizah; Irianta, Trika; Tahir, Mardiah; Chalid, Maisuri T.
Indonesian Journal of Obstetrics and Gynecology Volume 6. No. 1. January 2018
Publisher : Indonesian Socety of Obstetrics and Gynecology

Objective: To investigate the obstetric risk factors of the analincontinence in mothers with previous history of vaginaldelivery.Methods: The was a case-control study conducted in the Obstetricsand Gynecology Department of Dr.Wahidin Sudirohusodo Hospital,Faculty of Medicine, Universitas Hasanuddin, Makassar, during theperiod of February 2015 through January 2016. The researchinstruments were used to evaluate obstetric risk factors and theanal incontinence was the self-administered questionnaire and FecalIncontinence Severity Index. The data were analyzed statisticallyusing the Chi-square test with the significant value of p<0.05.Results: A total of 300 subjects were recruited in this study. Theresearch results indicated that the parity of  3, the assisted vaginaldelivery history (vacuum extraction), and the prolong secondstage of labor had a significant correlation with the anal incontinencewith p value=0.026, OR (95% CI) = 1.8 (1.07-3.03), p=0.018with OR (95% CI) =3.65 (1.2-10.7) and p=0.006 with OR (95% CI)= 2.9 (1.2-6.7).The history of episiotomy and the delivery of thebaby  4000 gram had no correlation with the anal incontinence.Conclusion: Parity, vacuum delivery and prolong second stage oflabor have an association with anal incontinence among womenwho has history of vaginal delivery.Keywords: anal incontinence, obstetric risk factors, vaginal delivery

Hubungan antara Kadar Hepsidin dan Kadar Hemoglobin pada Kehamilan dengan Obesitas Ratnaningsih, Andi Sri; Sunarno, Isharyah; Madya, Fatmawati; Hamid, Firdaus; Irianta, Trika; Susiawaty, Susiawaty
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.583

Tujuan: Untuk menilai kadar Hepsidin dan kadar hemoglobin menggunakan sampel darah dan selanjutnya dianalisis dengan metode ELISA.Metode: Penelitian ini merupakan kohort prospektif pada perempuan hamil dengan obesitas dan pembanding non-obesitas pada trimester pertama dan kedua di RSUP Dr. Wahidin Sudirohusodo dan Rumah Sakit Pendidikan Jejaring pada periode Januari - Agustus 2022.Hasil: Penelitian dilakukan terhadap 44 sampel yang terdiri atas 22 sampel kelompok ibu hamil dengan obesitas dan 22 sampel ibu hamil dengan IMT normal. Pada pasien obesitas tidak didapatkan korelasi antara kadar Hepsidin dan kadar hemoglobin di trimester pertama dengan nilai p=0.097 sedangkan pada trimester kedua terdapat korelasi dengan nilai p=0.028. Pada pasien non obesitas tidak didapatkan korelasi antara kadar Hepsidin dengan kadar hemoglobin nilai p=0.489 di trimester pertama dan nilai p=0.906 di trimester kedua.Kesimpulan: Peningkatan kadar Hepsidin dan anemia dapat ditemukan pada wanita obese yang sedang hamil, terutama pada trimester kedua.The Relationship Between Hepcidin Levels And Hemoglobin Levels In Pregnancy With ObesityAbstract Objective: To compare hepcidin levels and hemoglobin levels using blood samples and further analyzed with ELISA method.Method: This study is a prospective cohort of obese pregnant women and a non-obese comparator in the first and second trimesters at RSUP Dr. Wahidin Sudirohusodo Hospital and Networking Teaching Hospitals in the period January - August 2022.Results: The study was conducted on 44 samples consisting of 22 samples of obese pregnant women and 22 samples of pregnant women with normal BMI. In obese sample, there was no correlation between hepcidin levels and hemoglobin levels in the first trimester with a value of p=0.097 while in the second trimester there was a correlation with a value of p=0.028. In non-obese patients, there was no correlation between hepcidin levels and hemoglobin levels, p = 0.489 in the first trimester and p= 0.906 in the second trimester.Conclusion: Increased hepcidin levels and anemia can be found in obese women in the second trimester of pregnancy.Key words: Hepcidin, Obesity, Hemoglobin

Hubungan 8 OHdG (8-Hydroxy-2- Deoxyguanosin) Urin Neonatus dan Preeklamsia Tannur, Sebastianus; Lukas, Efendi; Mailoa, Johnsen; Alasiry, Ema; Irianta, Trika; Chalid, Maisuri T.
Indonesian Journal of Obstetrics & Gynecology Science Volume 7 Nomor 1 Maret 2024
Publisher : Dep/SMF Obstetri & Ginekologi Fakultas Kedokteran Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/obgynia.v7i1.582

Pendahuluan: Preeklamsia merupakan penyakit dengan berbagai teori (disease of theory) yang menggambarkan ketidakpastian patofisiologi dan penyebabnya. preeklamsia bukan hanya menyebabkan komplikasi terhadap maternal namun juga menimbulkan komplikasi terhadap janin, baik jangka pendek maupun jangka panjang. Peningkatan jumlah radikal bebas merupakan tanda terjadinya stres oksidatif pada kehamilan dengan preeklamsia. 8-OHdG adalah produk utama yang dibentuk dari radikal hidroksil pada residu guanine DNA.Metode: Penelitian ini merupakan penelitian analitik yang dikembangkan dengan desain penelitian cross-sectional. Sampel penelitian adalah neonatus yang lahir dari wanita hamil dengan dan tanpa didiagnosa preeklamsia. Pengambilan sampel dilakukan secara purposive sampling. dilakukan di Rumah Sakit Wahidin Sudirohusodo,dan rumah sakit jejaring pendidikan. Pengujian/running sampel dilakukan di unit Laboratorium Penelitian RSPTN Universitas Hasanuddin dengan metode Elisa. Data dianalisis dengan uji Chi squae, uji Mann whitney dan uji Kruskal wallis Hasil: Hasil penelitian yang telah dilakukan terdapat sebanyak 82 orang yang terbagi menjadi 41 orang sampel yang merupakan kelompok dengan preklamsia dan 41 orang sampel kelompok kontrol (normal). Berdasarkan hasil penelitian yang telah dilakukan mengenai kadar 8-OHdG urin neonatus (8-hydroxy-2- deoxyguanosin) pada kehamilan dengan Preeklamsia diperoleh nilai rerata kadar 8-OHdG urin neonatus pada kehamilan normal sebesar 3.79±1.99, sedangkan kehamilan dengan preeklamsia sebesar 14.25±16.81. uji statistik chi-square menunjukkan nilai p sebesar 0.00 dimana nilai p<0.05 yang artinya terdapat perbedaan kadar 8-OHdG urin neonatus terhadap kejadian preeklamsia dan ibu hamil normal pada penelitian ini. Kesimpulan: Terdapat perbedaan yang signifikan bermakna kadar 8-OHdG urin neonatus yaitu lebih tinggi kadar pada ibu hamil penderita preeklamsia daripada ibu hamil normal.Relationship Between 8 OHdG (8-Hydroxy-2- Deoxyguai›osine) in Neonate Urine and PreeclampsiaAbstractIntroduction: Preeclampsia is a disease with various theories (disease of theory) that describes the uncertainty of its pathophysiology and causes. Preeclampsia not only causes complications for the mother but also causes complications for the fetus, both short and long term. An increase in the number of free radicals is a sign of oxidative stress in preeclampsia. 8-OHdG is the main product formed from hydoxyl radicals in DNA guanine residues. Method: The research was an analytical study developed with a cross-sectional research design. The research sample was neonates born to pregnant women with and without a diagnosis of preeclampsia. The sample was determined by using purposive sampling technique carried out at Wahidin Sudirohusodo Hospital and educational network hospitals. Sample testing was carried out at Hasanuddin University RSPTN Research Laboratory unit using Elisa method. Data were analyzed using Chi square test, Mann Whitney test, and Kruskal Wallis test. Results: The research was carried out to 82 people who were divided into 41 samples in the group with preeclampsia and 41 samples in the control group (normal). Based on the results of research that has been carried out regarding the level of 8-OHdG in neonate urine (8-hydroxy-2-deoxyguanosine) in pregnancies with preeclampsia, the mean value of 8-OHdG level in neonate urine in normal pregnancies is 3.79 z 1.99, while the one in pregnancies with preeclampsia it is 14.25 z 16.81. The chi-square statistical test shows a p value 0.00 which p value <0.05, which means that there is a difference in the level of 8-OHdG in neonate urine in the occurrence of preeclampsia and normal pregnant women. Conclusion: There is a significant difference between the level of 8-OHdG in neonate urine, where the level is higher in pregnant women with preeclampsia than in normal pregnant women.Key words: 8-OHdG, neonate urine, preeclampsia

Kegiatan Pengabdian Penyuluhan Kesehatan, Perawatan Antenatal, dan Pemeriksaan USG Obstetri Dasar Terbatas pada Ibu Hamil M, Nasrudin A; Mochtar, Shulhana; Makmun, Armanto; Faisal Syamsu, Rachmat; Irianta, Trika; Dewi M, Anna Sari; Hamsah, Hamsah; Asmi, Muh. Nurul; Avisha, Mirah; Ulfa, Nura; Satria, Anna; Hilman, Feisal; Usmiah Musa, Amelia; Ashlihati, Munifah
Jurnal Pengabdian Kedokteran Indonesia Vol 6 No 1 (2025): Maret 2025
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/jpki.v6i1.330

Kegiatan yang berorientasi kepada masyarakat merupakan salah satu tridarma perguruan dibidang pengabdian. Dalam rangka rangkaian acara Bakti Sosial Akbar, kami dari Fakultas Kedokteran UMI bekerjasama dengan Pemerintah Kabupaten Mamuju Tengah menyelenggarakan bantuan tenaga dan materi di lokasi wilayah Kabupaten Mamuju Tengah berupa penyuluhan, perawatan Antenatal dan Pemeriksaan USG obstetri dasar terbatas pada ibu hamil. Kegiatan ini diagendakan pada tanggal 21 September 2024 bertempatkan di Rumah Jabatan Bupati Kabupaten Mamuju Tengah. Pelaksanaan kegiatan Penyuluhan Kesehatan dengan judul Tanda-Tanda Bahaya Kehamilan, pemeriksaan anc dan pemeriksaan usg dengan jumlah peserta sebanyak 107 orang yang berasal dari 5 kecamatan dan lebih dari 15 desa. Tujuan utama dari bakti sosial ini adalah untuk meningkatkan kesehatan ibu dan bayi serta mengurangi angka kematian ibu (AKI) dan bayi (AKB) melalui deteksi dini kondisi kesehatan melalui USG. Dengan terselenggaranya kegiatan ini, diharapkan Mahasiswa Pendidikan Profesi Dokter Spesialis (MPPDS) Obstetri dan Ginekologi FK UMI dapat memahami kondisi sosial masyarakat dan menambah pengetahuan mereka tentang realitas kehidupan melalui interaksi dengan masyarakat, mahasiswa dapat mengembangkan sikap peduli, moralitas tinggi, dan jiwa kepemimpinan.

Ureteric Injury During Hysterectomy: A Case Report Ulfa, Nura; Irianta, Trika; Hamsah, M.; A.M., Nasrudin; Fujiko, Masita; Nulanda, Mona
Journal La Medihealtico Vol. 6 No. 6 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i6.2753

Ureteral trauma is an uncommon but serious iatrogenic complication of hysterectomy, with risk influenced by surgical indication, patient factors, and intraoperative conditions. A 50-year-old woman presented with oliguria six days after hysterectomy for uterine myoma. She had abdominal distension and mild tenderness, with laboratory findings showing impaired renal function. Ultrasonography revealed bilateral hydroureteronephrosis and intraperitoneal ascites. Emergency exploratory laparotomy identified approximately 1.5 liters of intraperitoneal urine, bilateral ureteral dilatation, and bilateral distal ureteral ligation with urine leakage. Surgical management included intraperitoneal drainage, bilateral ureteroneocystostomy, ureteral stenting, peritoneal lavage, and bladder drainage. Eight days later, the patient developed abdominal wound dehiscence and underwent bilateral ureterocutaneostomy in collaboration with a urology surgeon. At follow-up, the patient showed gradual improvement and was able to resume daily activities under regular outpatient monitoring. Management of ureteral trauma depends on the timing of diagnosis, extent of injury, and associated complications. Early recognition and appropriate surgical intervention are essential to preserve renal function and reduce morbidity. Bilateral ureteral ligation is a rare but severe complication of hysterectomy, often presenting with postoperative anuria or oliguria and requiring urgent urological management. Careful intraoperative identification of the ureters and close monitoring of urine output are critical to prevent and promptly detect ureteral injury.

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