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All Journal Jurnal Gizi dan Pangan Wisanggeni : Jurnal Pengabdian Masyarakat
Binti Maulina
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The Effect of Combined Extracts of Sappan Wood (Caesalpinia sappan L.) and Gotu Kola (Centella asiatica L.) in Improving Diabetic Condition in Rats Binti Maulina; Wasita, Brian; Febrinasari, Ratih Puspita
Jurnal Gizi dan Pangan Vol. 17 No. 1 (2022)
Publisher : The Food and Nutrition Society of Indonesia in collaboration with the Department of Community Nutrition, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (308.931 KB) | DOI: 10.25182/jgp.2022.17.1.37-46

Abstract

This study aimed to determine the efficacy of combination of sappan (secang) wood and gotu kola extracts in reducing insulin resistance and Malondialdehyde (MDA) levels in diabetic rats induced by Streptozotocin (STZ) 65 mg/kg Body Weight (BW) and Nicotinamide (NA) 230 mg/kg BW. Forty-two male Sprague Dawley rats weighing ±200 g were divided into 7 groups: 1) control, 2) glibenclamide 0.45 mg/kg BW, 3) sappan wood extract (CS) 250 mg/kg BW, 4) gotu kola extract (CA) 500 mg/kg BW, 5) 1st combination of extracts of sappan wood and gotu kola (CSCA1) 125 mg/kg BW + 750 mg/kg BW, 6) 2nd combination (CSCA2) with 250 mg/kg BW + 500 mg/kg BW, and 7) 3rd combination (CSCA3) with 375 mg/kg BW + 250 mg/kg BW. The insulin resistance levels were measured using the HOMA-IR index based on fasting blood glucose and insulin. The Thiobarbituric Acid Reactive Substance (TBARs) method was used to measure MDA levels. All measurements were taken before treatment, 14 days after treatment, and 21 days after treatment. The group receiving CSCA3 showed significant reduction in insulin resistance (-3.32±0.05) and MDA levels (-2.04±0.37 nmol/ml) on Day 21 after treatment. The CSCA3 treatment did not show statistically different result compared to glibenclamide treatment (p>0.05). Hence, CSCA3 treatment was considered as the best proportion of sappan wood and gotu kola extracts mixture and the result is comparable to glibenclamide. This study shows that the combination of sappan wood and gotu kola extracts has the potential to be developed as a functional drink for people with diabetes.
Pemberdayaan UMKM Arang Briket Tempurung Kelapa bagi Masyarakat Desa Negara Agung Lampung Utara Eka Yuniasih; Apriza; Ardian Saputra; Ari Almansyah; Arif Bagas Sanjaya; Binti Maulina; Cahyani Wulandari; Chesia Afriza; Chintia Anggraini; Muhammad Amir Syuhada
Wisanggeni: Jurnal Pengabdian Masyarakat Vol. 5 No. 2 (2025): Desember (2025) Wisanggeni : Jurnal Pengabdian Masyarakat
Publisher : Institut Agama Islam Ma’arif NU (IAIMNU) Metro Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25217/wisanggeni.v5i2.6623

Abstract

Indonesia, as one of the largest coconut producers in the world, continues to face challenges in optimizing the economic potential of coconut shell waste, which is often discarded or used as low-value traditional fuel. In Desa Negara Agung, Lampung Utara, this issue is also evident, while the community simultaneously struggles with limited knowledge of production techniques, managerial capacity, and digital marketing strategies for developing coconut shell briquette enterprises. This community service activity, implemented through the Community Service Program (KKN), aimed to empower local MSMEs by transforming coconut shell waste into high-quality, eco-friendly briquettes. The program was grounded in empowerment theory and the Asset-Based Community Development (ABCD) approach, emphasizing active participation and utilization of local resources. Methodologically, it applied Participatory Action Research (PAR) with stages of problem identification, planning, action, evaluation, and reflection. The findings demonstrate improvements in briquette production skills, innovations in hygienic and attractive packaging, and the adoption of digital marketing platforms. These outcomes indicate that the program not only enhanced the economic capacity of local MSMEs but also supported environmental sustainability through the productive use of coconut shell waste.
Co-Authors apriza Ardian Saputra Ari Almansyah Arif Bagas Sanjaya Brian Wasita Cahyani Wulandari Chesia Afriza Chintia Anggraini Eka Yuniasih Muhammad Amir Syuhada Ratih Puspita Febrinasari