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Vaccination with the Incidence of Post-Acute Sequelae COVID-19 Aurelia, Daisy; En Masrika, Nur Upik; Rahman, Ismail
Jurnal Kesehatan Masyarakat Vol 19, No 3 (2024)
Publisher : Department of Public Health, Faculty of Sport Science, Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/kemas.v19i3.46447

Abstract

Post-acute sequelae COVID-19 (PASC) symptoms are present in the vast majority of COVID-19 survivors, even those who have received the COVID-19 vaccine. Until now, vaccines against PASC are still controversial. Some previous findings suggest that vaccines can reduce or worsen PASC symptoms. In addition, there has been no related research in North Maluku Province, especially in Ternate City. This study aims to determine the relationship between vaccine administration and PASC based on the total dose and type of vaccine obtained using a questionnaire-based cross-sectional design questionnaire. The study population was COVID-19 patients diagnosed with RT-PCR or RDT-Ag in 2020–2022, domiciled in Ternate City. The respondents were 133 people. Bivariate analysis showed no effect of vaccine dose administration on the incidence of PASC (P=0.111). Similarly, the type and dose of vaccine based on the did not affect (first dose, P = 1.000), (second dose P = 0.732), and (booster P = 0.434) PASC. In terms of the timing of booster doses, pre- and post-COVID-19, there was no significant effect (P=0.384). However, there was a higher incidence of PASC in responders who received the booster dose post-COVID-19. There is no association between vaccine administration and the incidence of PASC.
Identification of Gram Negative Bacteria in the Urine of Catheterized Patients at Referral Hospital in Ternate Waraningsih, Septiana; Do Toka, Wahyunita; Dahlan, Muhammad; Rachman, Ismail
Jurnal Kedokteran Brawijaya Vol. 33 No. 2 (2024)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jkb.2024.033.02.5

Abstract

Infections can occur anywhere and often occur usually sourced from hospitals. Nosocomial infection is an infection caused by various microorganisms, one of which is bacteria originating from the hospital environment. Gram-negative bacteria, especially the Enterobacteriaceae family, are the main bacteria that cause nosocomial infections. One of the common infectious diseases in health care is urinary tract infection and some UTIs are caused by catheter insertion. This research aimed to identify gram-negative bacteria in the urine of catheterized patients at RSUD Dr. H. Chasan Boesoirie, a referral hospital in Ternate. The research method is descriptive observational with a cross sectional approach using a total sampling technique obtained 83 samples from November 14, 2023 to December 17, 2023. The results showed that 7 samples (8.4%) were identified as positive for gram-negative bacteria with 7 types of bacterial species and the highest percentage of bacteria was Escherichia coli (33.4%). The use of urinary catheters was mostly female (55.4%) with the highest age in the age group 56-65 years (34.9%) and the duration of urinary catheter use was mostly in samples with a duration of <72 hours (90.4%). In conclusion, gram-negative bacteria were identified in the urine of catheterized patients.
SURVEILANS KESEHATAN MASYARAKAT PESISIR PULAU MAITARA (STUDI DI KECAMATAN TIDORE UTARA KOTA TIDORE KEPULAUAN) Husen, Abd Hakim; Rahman, Ismail
JURNAL ILMIAH OBSGIN : Jurnal Ilmiah Ilmu Kebidanan & Kandungan P-ISSN : 1979-3340 e-ISSN : 2685-7987 Vol 15 No 4 (2023): DESEMBER
Publisher : NHM PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36089/job.v15i4.1710

Abstract

Coastal areas are transition areas between land and sea ecosystems. The majority of coastal communities are fishermen, a group of people who are prone to poverty because their work is greatly influenced by weather conditions and seasons. Another problem that often arises in coastal areas is in the field of public health because they are transitional areas that can control sanitation in all physical factors of the human environment which may cause things that are detrimental to the physical development of human health and survival. This research aims to explore public health problems that occur on Maitara Island, North Tidore District, Tidore Archipelago City as one of the coastal cities in Indonesia. This research uses a descriptive survey conducted through field observations by directly observing the conditions and health problems that exist in coastal communities on Maitara Island, North Tidore District, Tidore Islands City.
Uji Standarisasi Parameter Spesifik dan Nonspesifik serta Penetapan Kadar Total Fenolik Ekstrak Daun Kelor (Moringa Oleifera) Rahmiyati Hi Samang; Fahmi Sadik; Ismail Rahman
Jurnal Syntax Admiration Vol. 6 No. 1 (2025): Jurnal Syntax Admiration
Publisher : Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jsa.v6i1.1622

Abstract

This study aims to standardize specific and non-specific parameters and determine the total phenolic levels in moringa leaf extract (Moringa oleifera) taken from Ternate. The standardization of specific parameters includes organoleptic, ethanol soluble juice content, and watersoluble juice content, while nonspecific parameters include drying shrinkage, moisture content, and ash content. The determination of total phenolic levels was carried out using the Folin-Ciocalteu method. The results of the study showed that moringa leaf extract met the requirements of standardization of specific and non-specific parameters according to the Indonesia Herbal Pharmacopoeia. The total phenolic content was expressed in Gallic Acid Equivalent (GAE) units of 206.36 mg GAE/g sample. This study shows that moringa leaf extract has good quality and safety in accordance with pharmaceutical standards.
UJI CEMARAN BAKTERI COLIFORM PADA DEPOT AIR MINUM ISI ULANG DI KECAMATAN TERNATE SELATAN Setiawan, Stefani Titis Evanda; Ismail Rahman; Dewi Darmayanti
Journal of Innovation Research and Knowledge Vol. 5 No. 7 (2025): Desember 2025
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

According to the World Health Organization (WHO) and the American Public Health Association (APHA), drinking water quality is determined by the presence and number of bacteria, with Coliform bacteria commonly used as microbiological indicators of contamination and potential presence of pathogenic microorganisms such as Escherichia coli. In 2022, the highest incidence of diarrhea in Ternate City was reported in Kalumata Village, South Ternate District, raising concerns regarding the microbiological quality of refill drinking water consumed by the community. This study aimed to determine the presence of Coliform bacteria contamination in refill drinking water depots in South Ternate District. A laboratory-based experimental study was conducted by collecting 18 refill drinking water samples from different depots, which were examined using the Most Probable Number (MPN) method. The results showed that 14 of 18 samples (77.78%) were positive for Coliform bacteria, with MPN values exceeding 0 per 100 mL. In conclusion, Coliform bacteria contamination was found in the majority of refill drinking water depots in South Ternate District, indicating that several depots did not meet the microbiological quality standards for drinking water.
The Immunomodulatory Potential of Ethanolic Extract of Blue Butterfly Pea Flower (Clitoria ternatea) on Non-Specific Immune Mechanisms Ermalyanti Fiskia; Muhammad Azhar A Karim; Muhammad Fakhrur Rajih Hi Yusuf; Rufaidah Azzahra; Ismail Rahman
Jurnal FARMASIMED (JFM) Vol 8 No 2 (2026): Jurnal Farmasimed (JFM)
Publisher : Fakultas Farmasi Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/s67fbc03

Abstract

The immune system is a complex mechanism consisting of cells, tissues, and organs that work in coordination to protect the body from exposure to pathogens. However, pathogens also possess strategies to counteract immune defenses, thereby necessitating external substances to support immune enhancement. One such substance is antioxidants. Butterfly pea flower (Clitoria ternatea) is a potential candidate as an immunomodulator due to its high antioxidant content, which functions to prevent lipid peroxidation and combat free radicals. This study aims to investigate the immunomodulatory potential of the ethanol extract of butterfly pea flower using the carbon clearance test in mice. The research method was experimental, employing 30 BALB/c mice as test animals, which were divided into six groups: Butterfly Pea Flower Extract (EBTB) at doses of 150, 300, and 600 mg/kg BW, levamisole 25 mg and methylprednisolone 4 mg as comparison groups, and sodium CMC as the negative control group. The substances were administered orally for seven consecutive days, followed by intravenous induction of carbon ink on day 8. The obtained serum was measured for absorbance using UV-Vis spectrophotometry at 650 nm. Parameters observed included the phagocytic index (PI) and lymphoid organ index (liver, spleen, and thymus). Based on the phagocytic index calculation, EBTB at doses of 150 and 300 mg/kg BW yielded values of 2.990 and 2.929, respectively, indicating strong immunostimulant activity, while BPFE at 600 mg/kg BW showed moderate immunostimulant activity with a PI value of 1.423. Results for the lymphoid organ index in the BPFE 150 group did not show significant differences (P > 0.05) compared to the control group. In conclusion, the ethanol extract of butterfly pea flower demonstrates potential as an immunomodulator for nonspecific immune responses.
Study of Coastal Community Health in North Maluku in the Utilization of TOGA Liasari Armaijn; Nur Upik En Masrika; Amran Nur; Ismail Rahman; Muhammad Fakhrur Rajih; Abdul Hamid Siragih
SAINTIFIK@: Jurnal Pendidikan MIPA Vol 11 No 1 (2026): SAINTIFIK@: Jurnal Pendidikan MIPA EDISI MARET 2026
Publisher : Universitas Khairun

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33387/saintifik.v11i1.10951

Abstract

Background: This study aims to examine the profile of Family Medicinal Plant (Tanaman Obat Kelaurga (TOGA) utilization among coastal communities on Hiri and Guaeria Islands as part of local wisdom-based health improvement efforts. Method: The study employed a mixed methods design involving 210 respondents. Quantitative data were obtained through questionnaires regarding knowledge, attitudes, and practices regarding TOGA utilization, while qualitative data were obtained through in-depth interviews and observations of medicinal plant processing and use practices in households. The results indicate that community knowledge of TOGA is in the fair category (53%), with an average score of 2.13. The community is generally familiar with several types of medicinal plants, such as ginger, turmeric, lemongrass, and betel leaf, for minor treatments. However, utilization practices remain limited, particularly in terms of sustainable processing and maintenance of medicinal plants. The main obstacles include limited land, knowledge of formulations, and lack of support from health workers. Conclusion: Overall, TOGA in coastal areas still has significant potential for development as part of a health promotion strategy and the resilience of traditional medicine communities. Community-based interventions are needed to increase community capacity in sustainable TOGA cultivation, processing, and utilization.