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All Journal Jurnal Veteriner Jurnal Anestesiologi Indonesia Journal of Tropical Biodiversity and Biotechnology Journal of Health Sciences Journal Orthopaedi and Traumatology Surabaya (JOINTS) Jurnal Layanan Masyarakat (Journal of Public Service) Jurnal Syntax Transformation Jurnal Neuroanestesi Indonesia Jurnal Widya Medika

Hamzah Hamzah

Departemen Anestesiologi Dan Reanimasi Universitas Airlangga, Rumah Sakit Dr. Soetomo Surabaya

Author-ID : 2409100

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Articles

The Difference of Results in Abdomen and Anus Area Measurement With Non-Contact Infrared Thermometer Anna Surgean Veterini; Nancy Margarita Rehatta; Hamzah Hamzah; Widijiati Widijiati; Sarmanu Sarmanu; Subijanto Marto Soedarmo; Widodo Jatim Pudjirahardjo; Annis Catur Adi; Heni Rachmawati; I Ketut Sudiana
Jurnal Veteriner Vol 22 No 2 (2021)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

Study about sepsis is chalenging to get the right therapeutic method. One clinical signs of the sepsis mice model is changes in body temperature. An easy way to examine body temperature is using infrared non-contact thermometer. The aim of this study is to compare the body temperature obtained from infrared non-contact thermometer at the abdomen and anus area. We used male Mus musculus mice, body weight of 25–30 grams, were divided into 2 groups (control and treated groups). In the control group, mice were injected with NaCl 0.9% solution, with the amount of NaCl volume equal to LPS. In the treated group, mice were injected with 2.5 mg/kgBW of LPS intraperitoneally. Body temperature measurement was measured in abdomen (tabd) and anus (tan) area. Body temperature was measured at 8th and 24th hour after LPS or NaCl injection. Body temperature value result using tabd was higher than tan. LPS injection to mice produced an increase in body temperature but was not significant when compared to the control group (8th and 24th hour). The mean difference between tabd and tan in 8th hour control groups respectively were 2.12oC. The mean difference between tabd and tan in 24th hour control groups 4.6oC. The mean difference in treated groups (8th hour) was 4.66oC, while it was 4.77oC in the 24th hour treated groups. LPS could caused vasodilation of the vessels, the measurement area of non contact-infrared thermometer will be the most important factor to be considered; tan may closer to the physiology condition.

The Effectiveness of Intraoperative Ketamine and Fentanyl as Preemptive Analgesia Assessed with qNOX Score Wilesing Gumelar; Hamzah Hamzah; Christijogo Sumartono
JAI (Jurnal Anestesiologi Indonesia) Vol 13, No 2 (2021): Jurnal Anestesiologi Indonesia
Publisher : Perhimpunan Dokter Spesialis Anestesiologi dan Terapi Intensif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jai.v13i2.31900

Background: Inadequate management of intraoperative pain poses a risk of postoperative chronic pain complications. The use of preemptive analgesia before the onset of surgical incision stimulation was considered to prevent central sensitization. Clinical research around the terms of preemptive analgesia needs to be proven by nociception-based intraoperative monitoring. An objective modality with EEG guidance can provide information on noxious stimuli.Objective: To determine the effectiveness of ketamine and fentanyl administration as preemptive analgesia measured by qNOX scores through the CONOX tool.Methods: This study is a single-blinded randomized experiment with the division of two groups: control and treatment. The control group received preemptive fentanyl, and the treatment group received preemptive ketamine and fentanyl. Then the qNOX score was assessed during operation.Result: The qNOX score of the treatment group in minute-15 and 30 was lower than the control group (p = 0.007; p = 0.025), while in the minute-90 it was higher than the control group (p = 0.001). The mean first 1-hour qNOX score was lower in the treatment group (p <0.001), while in the second 1-hour was higher in the treatment group (p = 0.003). The mean total dose of fentanyl supplementation in the treatment group was lower than in the control group (71.3 ± 25.1 grams vs. 92.0 ± 28.3 grams; p = 0.044).Conclusion: The administration of combined ketamine and fentanyl as preemptive analgesia is more effective in the first hour of surgery compared to single preemptive fentanyl measured by qNOX score. Preemptive ketamine and fentanyl decrease the total dose of intraoperative fentanyl supplementation compared with single-dose preemptive fentanyl administration.

Biomass Production of Root and Shoot of Talinum paniculatum Gaertn. by Liquid and Solid Ms Medium with Plant Growth Hormone IBA Muhammad Hamzah Solim; Y. S. Wulan Manuhara
Journal of Tropical Biodiversity and Biotechnology Vol 1, No 2 (2016): December
Publisher : Universitas Gadjah Mada

Talinum paniculatum Gaertn. is one of traditional medicinal plant in Indonesia which has benefits such as for vitality and maintain blood circulation. The aim of this research is to obtain biomass production of root and shoot of T. paniculatum Gaertn. by liquid and solid MS medium with IBA. This research conducted to provide biomass as raw material for secondary metabolites test. Stems as explant were induced with four treatments (liquid MS, solid MS, liquid MS + 2 ppm IBA and solid MS + 2 ppm IBA) with five repetitions. Observation did for 28 days. The parameters are the percentage of explants which formed the root and shoot, morphology, fresh and dry biomass. Result shows that percentage of root and shoot have 100% in liquid and solid MS + 2 ppm IBA. Fresh and dry biomass of root and shoot in solid MS + 2 ppm IBA higher than the others. This research found callus in liquid and solid MS + 2 ppm IBA. Morphology of root in liquid MS has thin and friable, but thick in solid MS. Shoot in solid and liquid MS has thin, short and sturdy.

VETIVER ROOT PLANTING FOR PREVENTION AND MITIGATION OF LANDSLIDES IN DISASTER-PRONE AREAS, NGANJUK, EAST JAVA Arie Utariani; Soni Sunarso Sulistiawan; Hamzah Hamzah; Christrijogo Soemartono Waloedjo; Kun Arifi Abbas; Belindo Wirabuana; Teuku Aswin Husain; Maulana Hanif Ibrahim; Alivery Raihanda Armando
Jurnal Layanan Masyarakat (Journal of Public Services) Vol. 6 No. 1 (2022): JURNAL LAYANAN MASYARAKAT
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jlm.v6i1.2022.77-86

Landslide is the transfer of slope-forming material in the form of rocks, debris, soil moving down or out of the slope. Geolologically, landslides are a geological phenomenon with a movement of land such as falling rocks or large lumps of land (Nandi, 2007). The majority of Nganjuk Regency, East Java, is at high risk of landslides. Reporting from Tirto.id news on February 19, 2021, there was a landslide in Ngetos Subdistrict, Nganjuk which claimed many victims. Nineteen people died, 20 were injured and 10 houses were severely damaged. Ngetos village is the largest village with the most populous population in Nganjuk. Unit of Natural Disease Support from Faculty of Medicine, Community Service Team of the Department of Anesthesiology and Reanimation Faculty of Medicine Universitas Airlangga in collaboration with the Center of Environmental Health Engineering and Disease Control (BBTKLPP) Surabaya in efforts to overcome landslide disasters that occurred in Nganjuk. Assistance provided includes medical assistance and environmental development as one of the disaster mitigation efforts. One of the mitigation measures carried out through this activity is reforestation by planting vetiver roots. Vetiver Roots are known as landslide prevention plants because their roots can reach depths soil of down to 5 meters. One of the causes of landslides is the lack of vegetation on the ground so it is prone to movement, especially if it rains heavily because there is no anchoring. Therefore, this activity is considered important to prevent repeated landslides.

Hubungan Antara Tingkat Stres dan Kadar Kortisol Saliva dan Faktor Penyebab Stres Residen Anestesiologi dan Terapi Intensif pada Era Pandemi Covid-19 Andre Kurniawan; Arie Utariani; Hamzah; Nalini
Jurnal Syntax Transformation Vol 2 No 02 (2021): Jurnal Syntax Transformation
Publisher : CV. Syntax Corporation Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/jst.v2i2.229

Pandemi COVID-19 berdampak pada proses pendidikan residen anestesi yang merupakan salah satu garda depan pelayanan medis. Situasi seperti ini akan menambah stres dan beban mental yang berpotensi menurunkan imunitas tubuh dan kualitas pelayanan. Kortisol saliva merupakan biomarker stres yang reliabel dalam mengukur tingkat stres karena bersirkulasi akut dalam tubuh. Penelitian ini bertujuan menganalisis hubungan antara kadar kortisol saliva dengan tingkat stres residen anestesiologi dan terapi intensif di era pandemi COVID-19 yang diukur menggunakan perceived stress scale (PSS-10). Metode penelitian adalah observasional analitik dilakukan pada 40 residen anestesiologi usia 28-39 tahun dan dalam masa putaran stase ruang isolasi khusus (RIK) dan ruang resusitasi (RES) yang menangani pasien terpapar COVID-19 di RSUD Dr. Soetomo Surabaya pada bulan Agustus-September 2020. Hasil perhitungan statistik dengan Uji Spearman, hubungan antara PSS-10 dan kadar kortisol, tingkat stres ringan (25% vs 67,5%) dan stres sedang (75% vs 37,5%) secara statistik bermakna (p=0,005; r=0,388) Simpulan: Tingkat stres residen anestesiologi berdasarkan PSS-10 berkorelasi linear terhadap kadar kortisol saliva di era pandemi COVID-19. Faktor stres paling dominan yakni perasaan kesal akibat sesuatu terjadi secara mendadak dan gugup jika terjadi hal diluar kendali. PSS-10 layak dipertimbangkan sebagai modalitas alat ukur dalam menilai tingkat stres residen anestesi di era pandemi COVID-19.

Adherence Level Of Medical Personnel In Implementing 2019 Postoperative Pain Management Guidelines Nasrulloh Nasrulloh; Hamzah Hamzah; Arie Utariani; Dedi Susila
Jurnal Ilmiah Kesehatan Vol 14 No 02 (2021): Jurnal Ilmiah Kesehatan (Journal of Health Sciences)
Publisher : Universitas Nahdlatul Ulama Surabaya

Introduction: Inadequate pain management may increase the risk of complications and postoperative chronic pain. Postoperative Pain Management Guidelines of The Anesthesiology and Reanimation Department, Faculty of Medicine Universitas Airlangga/ Dr. Soetomo Hospital Surabaya were arranged in 2019. Purposes: This study aim is to analyze the medical personnel’s adherence in implementing postoperative pain management guidelines. Methods: This is descriptive observational study with retrospective design. Total sampling was carried out on the medical records of patients who underwent elective surgery and received postoperative acute pain management during March-May 2020. Results: A total of 349 patients, most of the pain intensity was moderate (62.8%). The medical personnel adherence with postoperative pain management guidelines was 88.0%. The overall use of multimodal analgesia was 61.0%. Adherence to guidelines on pain category was mostly good adherence: 99.1% in mild pain, 82.6% in moderate pain, and 81.2% in severe pain. The use of multimodal analgesia was found in 12.3% mild pain; 83.6% moderate pain, and 100% severe pain patients. Conclusion: Most of the medical personnel have adhered to the postoperative pain management guideline, and widely-used multimodal analgesia. Systematic evaluation of guidelines implementation, patient satisfaction, and outcomes are needed.

Penanganan Anestesi pada Pasien Pediatri dengan Cedera Otak Traumatik Sedang, Fraktur Impresi dan Edem Serebri Dhania A Santosa; Prihatma Kriswidyantomo; Pesta Parulian Maurid Edwar; Hamzah Hamzah
Jurnal Neuroanestesi Indonesia Vol 6, No 1 (2017)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Cedera otak traumatik merupakan penyebab terbanyak kecacatan dan kematian pada anak dan orang dewasa. Di Amerika Serikat, terjadi lebih dari 510.000 kasus cedera otak traumatik per tahun pada anak-anak usia 0-14 tahun;1 dengan 2.000–3.000 di antaranya meninggal setiap tahunnya. Tujuan dari penanganan cedera otak traumatik selain menangani cedera primernya, juga untuk mencegah terjadinya cedera sekunder. Seorang anak laki-laki usia 12 tahun mengalami kecelakaan lalu lintas dan didiagnosis dengan cedera otak traumatik sedang, fraktur impresi regio temporo parietal kanan dan edema serebri dengan komorbiditas anemia, rencana akan dilakukan pembedahan darurat untuk debridement, eksplorasi duramater dan rekonstruksi tulang. Pembedahan dilakukan dengan anestesi umum intubasi endotrakeal dan berjalan selama tujuh jam. Kondisi pasien selama pembedahan relatif stabil dan setelahnya dirawat di Ruang Observasi Intensif dengan bantuan ventilator. Setelah memastikan kondisi ekstrakranial normal, pasien kemudian disapih dari ventilator dan diekstubasi keesokan harinya. Pasien dipulangkan pada hari kedelapan setelah kejadian.Anesthesia Management in Pediatric Patient with Moderate Traumatic Brain Injury, Impression Fracture and Cerebral OedemaTraumatic brain injury is the leading cause of morbidity and mortality in pediatric and adult patients. In United States, 510,000 cases of traumatic brain injury occur each year in children aged 0-14 years;1 with 2.000-3.000 pass away each year. Cure the primary insult and prevent secondary injury are the important thing in traumatic brain injury. A 12-year-old boy had a motor vehicle accident and was diagnosed with moderate traumatic brain injury, impression fracture at the right temporo parietal region and cerebral edema, with anemia, planned for emergency surgery of debridement, duramater exploration and bone reconstruction. Surgery was done under general anesthesia using endotracheal intubation and lasted for seven hours. Patient’s condition remained relatively stable during surgery and was observed with ventilator supported in Intensive Observation Ward afterward. Once extracranial factors considered normal, patient was weaned and extubated the next day. Patient was sent home on the eight day after incident. Cedera otak traumatik merupakan penyebab terbanyak kecacatan dan kematian pada anak dan orang dewasa. Di Amerika Serikat, terjadi lebih dari 510.000 kasus cedera otak traumatik per tahun pada anak-anak usia 0-14 tahun;1 dengan 2.000–3.000 di antaranya meninggal setiap tahunnya. Tujuan dari penanganan cedera otak traumatik selain menangani cedera primernya, juga untuk mencegah terjadinya cedera sekunder. Seorang anak laki-laki usia 12 tahun mengalami kecelakaan lalu lintas dan didiagnosis dengan cedera otak traumatik sedang, fraktur impresi regio temporo parietal kanan dan edema serebri dengan komorbiditas anemia, rencana akan dilakukan pembedahan darurat untuk debridement, eksplorasi duramater dan rekonstruksi tulang. Pembedahan dilakukan dengan anestesi umum intubasi endotrakeal dan berjalan selama tujuh jam. Kondisi pasien selama pembedahan relatif stabil dan setelahnya dirawat di Ruang Observasi Intensif dengan bantuan ventilator. Setelah memastikan kondisi ekstrakranial normal, pasien kemudian disapih dari ventilator dan diekstubasi keesokan harinya. Pasien dipulangkan pada hari kedelapan setelah kejadian.

THE EFFECT OF TRANEXAMIC ACID INJECTION ON HEMOGLOBIN LEVEL, ALBUMIN LEVEL, AND PAIN ON PATIENT RECEIVING TOTAL KNEE REPLACEMENT Dwikora Novembri Utomo; Teddy Heri Wardhana; Ahmad Hannan Amrullah; Hamzah Hamzah
Journal Orthopaedi and Traumatology Surabaya Vol. 8 No. 1 (2019): April 2019
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/joints.v8i1.2019.1-11

Background: The high number of knee osteoarthritis cases could lead arthroplasty more frequent. Total Knee Replacement (TKR) surgery procedure is at risk of massive bleeding. Bleeding can affect albumin levels and the onset of intra-compartment pressure on the nerves. The use of tranexamic acid could be done to reduce bleeding.Objective: Proving the effect of intravenous tranexamic acid administration on patients who will undergo TKR surgery.Methods: The experiment was conducted experimentally using primary laboratory data obtained before and after surgery in patient which will be performed TKR operation starting from April 2017.Result: There are 64 patients who had undergone total knee replacement surgery. The mean preoperative hemoglobin in the tranexamic acid group and without tranexamic acid was 13.06±1.46g/dl and 12.44±0.87g/dl. The mean hemoglobin after surgery was 10.29 ±1.14 g/dl and 9.16±0.97 g/dl. In the group receiving tranexamic acid, 32 (100%) reported low postoperative VAS scores, did not require blood transfusions and did not require albumin transfusion. Groups not receiving tranexamic acid, 32 (100%) moderate postoperative VAS scores, 4 people (12.5%) required the blood transfusion, and 3 (9.4%) required transfusion of albumin.Conclusion: The results of this study showed that the group given tranexamic acid had higher hemoglobin levels after surgery than the untreated group of tranexamic acid; there was no difference in albumin levels after surgery in both groups; the administration of tranexamic acid will decrease the amount of blood loss, decrease the degree of pain, and decrease the need for blood transfusions after total knee replacement surgery.

Tatalaksana Kraniektomi Dekompresif pada Pasien Cedera Otak Traumatik Berat yang Disertai Peningkatan Tekanan Tinggi Intrakranial Menetap Fitri Sepviyanti Sumardi; Hamzah Hamzah; Sri Rahardjo; Tatang Bisri
Jurnal Neuroanestesi Indonesia Vol 7, No 3 (2018)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Tekanan tinggi intrakranial menetap adalah penyebab kematian terbesar pada pasien dengan cedera kepala traumatik berat. Pada cedera kepala berat, tatalaksana secara konservatif dan operatif dilakukan untuk meminimalisir terjadinya cedera otak sekunder. Peningkatan tekanan intrakranial biasanya disebabkan karena edema otak, hal ini sangat penting dan menentukan hasil luaran pasien/Glasgow outcomes scale (GOS) atau Extended GOS (GOSE). Data klinis menunjukkan bahwa kraniektomi dekompresif menurunkan angka kematian, meningkatkan fungsi pemulihan, menurunkan durasi perawatan di ICU dan meningkatkan hasil luaran berdasarkan Barthel Index Score. Kraniektomi dekompresif sering dilakukan sebagai penyelamatan empiris untuk melindungi kerusakan otak lebih lanjut akibat efek edema dan hipertensi intrakranial menetap. Konsep utama tatalaksana pasien dengan tekanan tinggi intrakanial yang menetap adalah menjaga aliran darah otak dan tekanan perfusi otak.Decompressive Craniectomy Management in Patients with Severe Traumatic Brain Injuries Accompanied by Refractory Intracranial HypertensionRefractory intracranial hypertension is the biggest cause of death in patients with severe traumatic head injury. In severe head injuries, conservative management and surgery are performed to minimize the occurrence of secondary brain injury. The increase in intracranial pressure is usually caused by brain edema, this is very important and determines the outcomes of the Glasgow outcomes scale (GOS) or extended GOS (GOSE). Clinical data show that decompressive craniectomy reduces mortality, improves recovery function, decreases duration of ICU treatment and increases outcome outcomes based on the Barthel Index Score. Decompressive craniectomy is often performed as an empirical salvage to protect further brain damage due to the effects of edema and refractory intracranial hypertension. The main concept of managing patients with refractory intracranial hypertension is to maintain cerebral blood flow and cerebral perfusion pressure.

Comparison General Anesthesia And Combined Scalp Block With Ropivacaine 0.5% On Mean Arterial Pressure, Heartrate And Fentanyl Consumption During Craniotomy. Rudi Iskandar Suryadani; Hamzah Hamzah; Nancy Margarita Rehatta; Arie Utariani
JURNAL WIDYA MEDIKA Vol. 6 No. 1 (2020): April
Publisher : FAKULTAS KEDOKTERAN UNIVERSITAS KATOLIK WIDYA MANDALA SURABAYA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jwm.v6i1.2499

Surgical craniotomy such as skin incisions, head pinning, periosteal-dural contact, dura closure, bones and skin can cause of nociceptive stimulation. These actions are stimuli to the nerves that can stimulate stress response. The stress response to surgery is characterized by increased secretion of the pituitary hormone and activation of the sympathetic nervous system. Hypothalamic activation of the sympathetic autonomic nervous system results in increased secretion of catecholamines from the adrenal medulla and the release of norepinephrine from the presynaptic nerve terminal. Objectives: This study is a single blind experimental, 14 patients with ages 18-60 years physical status ASA (American Society of Anesthesiologists) 1-3, with elective craniotomy surgery. This study was divided into two groups of subjects, group A with seven craniotomy subjects with general anesthesia and group B with seven craniotomy subjects combined with scalp block using ropivacaine 0.5%. Data collected then analyzed with SPSS. We found a decrease in MAP (Mean Arterial Pressure) and heart rate in the scalp block group during scalp incision (MAP p=0.002; HR p=0.029), periosteal contact (MAP p=0.025; HR p=0.039) significantly, as well as the use of fentanyl during surgery was significantly decreased (p=0.0001). General anesthesia with scalp block is more effective in reducing the increase in MAP, heart rate and fentanyl consumption during craniotomy.

Co-Authors Ahmad Hannan Amrullah Alivery Raihanda Armando Andre Kurniawan Anna Surgean Veterini Annis Catur Adi Belindo Wirabuana Christijogo Sumartono Christrijogo Soemartono Waloejo Dedi Susila Dhania A Santosa Dwikora Novembri Utomo Edwar, Pesta Parulian Maurid Fitri Sepviyanti Sumardi HENI RACHMAWATI Kun Arifi Abbas Maulana Hanif Ibrahim Nalini Nasrulloh Nasrulloh Prihatma Kriswidyantomo Rehatta, Nancy Margarita Rudi Iskandar Suryadani S.Pd. M Kes I Ketut Sudiana . Sarmanu, Sarmanu Sri Rahardjo Subijanto Marto Soedarmo Sulistiawan, Soni Sunarso Tatang Bisri Teuku Aswin Husain Utariani, Arie Wardhana, Teddy Heri Widijiati Widijiati Widodo Jatim Pudjirahardjo Wilesing Gumelar Y. S. Wulan Manuhara

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