Article Per Year (5 Year)
p-Index From 2021 - 2026
1.978
P-Index
This Author published in this journals
All Journal Jurnal Fitofarmaka Indonesia As-syifaa Jurnal Farmasi Jurnal Mandala Pharmacon Indonesia Jurnal Mandala Pengabdian Masyarakat KOPEMAS
Fitriana Fitriana
Fakultas Farmasi Universitas Muslim Indonesia
Biochemistry, Genetics & Molecular Biology Chemistry Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Social Sciences

Published : 22 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 22 Documents
Search

 1   2   3 
PENENTUAN WAKTU OPTIMUM PRODUKSI METABOLIT SEKUNDER ISOLAT BAKTERI ACTINOMYCETES DARI TANAH RHIZOSFER AKAR TANAMAN JARAK PAGAR (Jatropha curcas. L) TERHADAP BAKTERI PATOGEN Fitriana Fitriana; Rusli Rusli
As-Syifaa Jurnal Farmasi Vol 10, No 1 (2018): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (295.803 KB) | DOI: 10.33096/jifa.v10i1.331

Abstract

The study of optimum time determination of secondary metabolite production of Actinomycetes bacteria isolate from Jatropha curcas L root of the soil (Jatropha curcas (L) of pathogenic bacteria has been done with the aim to determine pathogen bacteria that can be inhibited by Actinomycetes bacteria and determine the optimum time in producing secondary metabolite to pathogenic bacteria. The first phase of this study is to isolate Actinomycetes purification IBPT 01. Then performed a screening test of activity against pathogenic bacteria. Furthermore, the timing of production of antibiotics or secondary metabolites with bacterial fermentation Actinomycetes IBPT 01 begins on the 1st day until the 28th day and carried out the activity of antibiotics for 28 days. The results obtained in the screening test Actinomycetes bacteria activity IBPT code 01 provides antibacterial activity with category which has a diameter of 20 mm 11- barriers against 8 bacteria while one bacterium with diameter> 20 mm including strong category. Optimization results showed that the isolated bacteria Actinomycetes capable of producing secondary metabolites on 9 day, 8 day, 7 day, 4 day and 26 day. From this research can be concluded that the bacterial isolates of Actinomycetes IBPT 01 can provide the optimum time to produce different secondary metabolites.
PROFIL BIOAUTOGRAM EKSTRAK FERMENTAT ISOLAT FUNGI ENDOFIT DARI DAUN GALING-GALING (Cayratia trifolia L) SEBAGAI ANTIBAKTERI Fitriana Fitriana; As Adi Abdullah; Annisa Almagfirah Achmar
As-Syifaa Jurnal Farmasi Vol 11, No 1 (2019): AS-SYIFAA Jurnal Farmasi
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (109.159 KB) | DOI: 10.33096/jifa.v11i1.494

Abstract

The research bioautogram profile of fermentate extract endophytic fungi from galing-galing (Cayratia trifolia L) leaf as an antibacterial has been to find the activity of the extract fermentat endophytic fungi isolates against bacterial test using TLC Bioautography. This research begins with the isolation of leaves galing-galing using Potato Dextrose Agar Chloramfenicol (PDAC) media, isolates do purification and macroscopic test. Subsquently isolates were followed by screening endophytic fungi isolates against test bacteria. Isolates that give the most excellent activity followed by fermentation with Maltose Yeast Broth (MYB) media using a shaker speed of 200 rpm at room temperature for 21 days. After the fermented liquid is separated to obtain fermentat and  mycelia. The fermented liquid was then extracted using a liquid-liquid extraction method using ethyl acetate solvents after which it was evaporated with a rotary evaporator until a thick extract was obtained. Extracts obtained followed by TLC Bioautography method using ethyl acetate : n-hexane (4: 1) eluent.  Endophytic fungi were obtained as many as 6 isolates and the best activity was endophytic fungi with IDGG-03 code against test bacteria. The results from the TLC Bioautography profile 2 Bioautography provide active spot with Rf values of 0.09 and 0.54 against the bacteria B. subtilis, V. cholerae and P. aeruginosa.
PENENTUAN AKTIVITAS ANTIBAKTERI EKSTRAK ISOLAT FUNGI ENDOFIT DARI DAUN GALING-GALING (Cayratia trifolia L) Ayyub Harly Nurung; Fitriana Fitriana; Herwin Herwin
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.785

Abstract

Utilization of wild plants around us needs to be done to expand the chances of wild plants being used as traditional medicine. These plants have the main content of the active compounds in the form of steroids, terpenoids, flavonoids, tannins and is reported to have antibacterial activity. This research aims to determine the concentration of endophytic fungi isolates IDGG 02, IDGG 03 and IDGG 06 from the leaves of galing-galing (Cayratia trifolia L). The first stage purification isolates of endophytic fungi in order to obtain single isolates. Then fermented using a shaker for 21 days at room temperature. Fermented extracted with ethyl acetate solvent using a liquid-liquid extraction methods to obtain a dry extract. Testing the minimum inhibitory concentration (MIC) with concentrations of 2048, 1024, 512, 256, 128, 64, 32, 16, 8 and 4 µg / mL and testing for antibacterial activity using agar diffusion methods against bacteria Staphylococcus aureus, Staphlococcus epidermidis, Escherichia coli and Vibrio cholerae.The results obtained MIC 2048 MIC ug / mL to extract isolates IDGG 02 and IDGG 06, while the extract obtained 03 isolates IDGG 1024 MIC ug / ml against all bacteria. Results of testing the antibacterial activity of endophytic fungi isolated extract IDGG 02, 03 IDGG produce diameter zone of inhibition at a concentration of 2048 mg / mL against Staphylococcus aureus, Staphlococcus epidermidis, Escherichia coli and Vibrio cholerae.
AKTIVITAS ANTIMIKROBA EKSTRAK ETANOL BATANG WOLE WOE ASAL HALMAHERA TENGAH TERHADAP BAKTERI GRAM POSITIF Staphylococcus epidermidis DAN Staphylococcus aureus Fitriana Fitriana; Sitti Amirah; Safriani Rahman
As-Syifaa Jurnal Farmasi Vol 14, No 1 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i1.793

Abstract

The wole woe plant is one of the plants empirically used by the Weda community in Central Halmahera district as a traditional medicine to treat various diseases such as breast cancer, cysts, vaginal discharge, diabetes mellitus, wounds, dysentery, cholesterol, and gout. Therefore, a study was conducted on the antimicrobial activity of the ethanolic extract of wole woe stems against gram-positive bacteria S. epidermidis and S. aureus with the aim of determining the concentration that provides antimicrobial activity of the ethanolic extract of wole woe stems by using the agar diffusion method. The results obtained in the screening test gave activity at a concentration of 0.1% and the results of the minimum inhibitory concentration test (MIC) and the minimum killing concentration test (MBC) obtained a MIC value of 1.6% for S. epidermidis bacteria and 0.8% for S. aureus bacteria, while the MBC value is 1.6% for both bacteria. The results of statistical tests on the diameter of the inhibition zone from the antimicrobial activity test against S. epidermidis and S. aureus, showed that there was a difference in the ability to inhibit bacterial growth between the positive control and the test concentration group of 2.5%, 5% and 10%. In the ratio of the inhibitory ability of bacteria at a spesific concentration, the test results showed that S. epidermidis bacteria had different bacterial growth inhibition abilities with S. aureus bacteria. Based on the results obtained, the ethanol extract of wole woe stems has potential as an antimicrobial.
POTENSI ANTIBAKTERI EKSTRAK ETANOL BATANG WOLE WOE ASAL HALMAHERAH TENGAH TERHADAP BAKTERI Pseudomonas aeruginosa dan Bacillus subtilis MENGGUNAKAN METODE DIFUSI AGAR Fitriana Fitriana; Sitti Amirah; Safriani Rahman; Bayu Putra
As-Syifaa Jurnal Farmasi Vol 14, No 2 (2022): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v14i2.904

Abstract

The wole woe plant empirically in the community in Central Halmaherah district is used to treat various diseases, such as breast anticancer, cysts, vaginal discharge, diabetes mellitus, wounds, dysentery, cholesterol, and uric acid, which is thought to have bioactive compounds, that is antibacterial compounds. Therefore, a study was conducted to determine the antibacterial potential of the ethanol extract of wole woe stems against Pseudomonas aeruginosa and Bacillus subtilis bacteria using the agar diffusion method. The results of the screening test showed activity at a concentration of 0.1% and the results of the minimum inhibitory concentration test (MIC) and the minimum killing concentration test (MBC) obtained 1.6% for Pseudomonas aeruginosa bacteria. For Bacillus subtilis bacteria, the MIC value is 0.2% and the MBC value is 3.2%. The statistical test results of the inhibition zone diameter data from the antibacterial activity test against Pseudomonas aeruginosa and Bacillus subtilis bacteria showed that there was a difference in the ability to inhibit bacterial growth between the positive control and the test concentration group of 2.5%, 5% and 10%. The results obtained from the ethanol extract of wole woe stems have potential as antibacterial.
AKTIVITAS ANTIMIKROBA EKSTRAK ETANOL BATANG WOLE WOE TERHADAP MIKROBA PATOGEN MENGGUNAKAN DIFUSI AGAR Fitriana Fitriana; Sitti Amirah; Safriani Rahman; Sukmawati Sukmawati
As-Syifaa Jurnal Farmasi Vol 15, No 1 (2023): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v15i1.967

Abstract

Infectious diseases can be caused by the entry of microorganisms such as bacteria, fungi, parasites, and viruses that can cause diseases in humans. One of the plants used empirically by the Weda community in Central Halmahera is the stem part of the wole woe plant. The aim of this study was to determine the antimicrobial activity of the ethanol extract of wole woe stems against pathogenic microbes such as Propionibacterium acnes, Escherichia coli, Salmonella thypi, Shigella dysentriae, Vibrio cholerae, and Candida albicans. This study used the agar diffusion method with various concentrations of 2.5%, 5%, and 10%, and positive controls for bacteria with chloramphenicol, positive controls for fungi with nystatin, and DMSO as a negative control. Based on the average diameter of the inhibition zone obtained, the test microbes were classified into the medium-strong category because they had an inhibition zone diameter ranging from 9 mm to 13 mm. The positive control for chloramphenicol for bacteria was classified into the very strong category because it had an inhibition zone diameter of >20 mm, while the positive control for nystatin for fungi was classified into the strong category because it had an inhibition zone diameter of >10 mm. Based on these tests, it can be concluded that the ethanol extract of wole woe stems has antimicrobial activity
AKTIVITAS ANTIINFLAMASII EKSTRAK ETANOL BATANG WOLE WOE PADA TIKUS DENGAN METODE RAT HIND PAW EDEMA Safriani Rahman; Sitti Amirah; Fitriana Fitriana; Bayu Putra
As-Syifaa Jurnal Farmasi Vol 15, No 1 (2023): AS-SYIFAA JURNAL FARMASI
Publisher : Fakultas Farmasi UMI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56711/jifa.v15i1.961

Abstract

Inflammation is the natural protective response of the body to tissue damage brought on by toxic chemicals, microbiological organisms, or physical trauma. The purpose of this investigation is to find out how active the ethanol extract of Wole woe stem is and how much of it is needed to get results. This anti-inflammatory study was conducted on 15 rats using the rat hind paw edema method. The rats were divided into 5 groups: group I served as a negative control (Na.CMC), group II served as a positive control (diclofenac sodium 0.9 mg/kgBW), groups III, IV, V received doses of Wole woe stem ethanol extract ranging from 100 mg/kgBW to 400 mg/kgBW, respectively. Oral administration was used for all the test materials, and after an hour, each test animal received a subplantar injection of 0.1 milliliters of 1% carrageenan solution. A plethysmometer was used to take readings every hour for a period of eight hours to get an accurate reading of the volume of the rat’s foot. The collected test results were subjected to statistical analysis, in which a one-way ANOVA and a post hoc LSD test were used. According to the findings of the research that was carried out, it was discovered that an ethanol extract of Wole woe stems possessed anti-inflammatory action, and the most effective dose was found to be 400 milligrams per kilogram of body weight (mg/kgBW).
PEMBUATAN COOKIES SEHAT UNTUK PENDERITA KOLESTEROL DI DESA PADDINGING KECAMATAN SANROBONE KABUPATEN TAKALAR Fitriana Fitriana; Safriani Rahman; Sitti Amirah; Ayyub Harly Nurung
Jurnal Mandala Pengabdian Masyarakat Vol. 4 No. 1 (2023): Jurnal Mandala Pengabdian Masyarakat
Publisher : Progran Studi Farmasi STIKES Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpm.v4i1.150

Abstract

Cookies merupakan makanan ringan yang rasanya enak dan renyah sehingga banyak dijadikan cemilan dan digemari masyarakat termasuk anak-anak, remaja, dan orang dewasa. Cookies sering dijadikan kudapan atau teman minum teh oleh masyarakat. Kandungan gula dan lemak yang tinggi menyebabkan cookies ini memiliki kalori yang tinggi. Selain itu, kandungan lemak dan gula tinggi dapat memicu obesitas jika sering di konsumsi. Tidak bisa dipungkiri bahwa kebiasaan makan camilan dengan kandungan kalori yang tinggi menjadi salah satu pemicu obesitas. Salah satu bahan yang berpotensi dan dapat digunakan sebagai bahan baku cookies adalah oat. Oat adalah biji-bijian yang bebas gluten dan merupakan sumber vitamin, mineral, serat, dan antioksidan. Kandungan antioksidannya dapat meningkatkan kolesterol baik di dalam tubuh dan dapat membantu menurunkan kolesterol total di dalam tubuh. Pada kegiatan pengabdian ini yang menjadi mitra adalah tim PKK di desa Paddinging, Kecamatan Sanrobone, Kabupaten Takalar. Desa ini merupakan salah satu desa mitra binaan Universitas Muslim Indonesia (UMI). Kegiatan pengabdian yang dilakukan untuk meningkatkan pengetahuan dan ketrampilan tentang pembuatan cookies sehat untuk penderita kolesterol dengan cara menjelaskan tentang cookies sehat dan pembuatan cookies yang menggunakan bahan utama yaitu oat. Hasil yang diperoleh dari kegiatan ini adalah meningkatnya pengetahuan dan ketrampilan dari tim PKK dapat dilihat dari pembuatan cookies yang dilakukan secara mandiri berdasarkan informasi yang diperoleh dari kegiatan pengbadian. Berdasarkan hal tersebut,  masyarakat di desa Paddinging, khususnya tim PKK telah mengetahui cara pembuatan cookies yang sehat untuk penderita kolesterol sebagai cemilan sehat.
Isolasi dan Uji Aktivitas Bakteri Asam Laktat dari Produk Fermentasi Kombucha Teh Dalam Menghambat Bakteri Escherichia coli, Staphylococcus aureus, dan Salmonella thypi Ismail Ismail; Fhahri Mubarak; Restu Islamia Rasyak; Rusli Rusli; Fitriana Fitriana; Harlyanti Muthma'innah Mashar
Jurnal Mandala Pharmacon Indonesia Vol. 9 No. 2 (2023): Jurnal Mandala Pharmacon Indonesia
Publisher : Program Studi Farmasi Universitas Mandala Waluya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35311/jmpi.v9i2.386

Abstract

Bakteri asam laktat atau juga disebut mikroorganisme probiotik merupakan bakteri yang memiliki kemampuan menghasilkan asam organik. Bakteri asam laktat yang terkandung pada kombucha teh diketahui mempunyai kemampuan dalam menghambat bakteri patogen seperti Eschericia coli, Staphylococcus aureus, dan Salmonella thypi. Tujuan dari penelitian ini yaitu untuk mengetahui bagaimana bakteri asam laktat yang dihasilkan dari fermentasi kombucha teh dalam menghambat akivitas bakteri Eschericia coli, Staphylococcus aureus, dan Salmonella thypi dengan metode in vitro. Prosedur penelitian ini dilakukan dalam beberapa tahapan yaitu preparasi teh kombucha, isolasi dan seleksi bakteri asam laktat, identifikasi bakteri asam laktat dengan metode pewarnaan Gram, uji biokimia dengan metode uji katalase dan uji motilitas, dan uji aktivitas antibakteri menggunakan kertas cakram. Dari hasil penelitian dengan karakteristik mikrosopik pewarnaan Gram menunjukkan hasil Gram positif,dan karekteristik makroskopik pada uji katalase negatif, uji motilitas negatif, dan daya hambat isolat 5 dan 6 memiliki kemampuan dalam menghambat bakteri uji. Diameter penghambatan yang didapatkan yaitu pada Staphylococcus aureus diameter penghambatan yaitu 7,1±0,52 mm dan 7,65±0,38 mm, pada Escherichia coli diameter penghambatan yaitu 7,86±0,08 mm dan 6,36±0,29 mm dan pada Salmonella thypi diameter penghambatan yaitu 6,43±0,06 mm dan 7,13±0,08 mm. Isolat yang didapatkan dari kombucha teh yaitu sebanyak 6 isolat, dan merupakan bakteri Gram positif, bentuk sel bulat, berwarna putih tulang, dengan tepi entire dan elevasi flat, yang diketahui memiliki potensi dalam menghambat bakteri Eschericia coli, Staphylococcus aureus, dan Salmonella thypi.
PEMBUATAN HAND SANITIZER DAN PENYULUHAN CUCI TANGAN YANG BENAR DI BEBERAPA SEKOLAH KOTA MAKASSAR Rizqi Nur Azizah; Hendra Herman; Fitriana Fitriana
Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024 Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) 2020
Publisher : Konferensi Nasional Pengabdian Masyarakat (KOPEMAS) #5 2024

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Salah satu upaya untuk memutus rantai penyebaran COVID-19 adalah dengan menerapkan kebiasaan mencuci tangan. Kegiatan pengabdian ini bertujuan untuk memperkenalkan kepada siswa, orang tua, dan guru di beberapa Sekolah Dasar di Kota Makassar  mengenai pembuatan hand sanitizer dari bahan sederhana dan penyuluhan tentang cara cuci tangan yang benar berdasarkan rekomendasi dari WHO. Lembaga mitra pada kegiatan pengabdian ini adalah SDIT Wihdatul Umma (SDIT-WU) dan Nur Miyazaki Islamic Character School (NICS). Metode yang dilakukan untuk mencapai target dalam kegiatan pengabdian ini meliputi sosialisasi kegiatan pengabdian kepada pihak NICS dan SDIT Wihdatul Ummah, penyuluhan cara cuci tangan yang benar dengan metode ceramah dan diskusi, lalu dilanjutkan  dengan pelatihan pembuatan hand sanitizer, serta evaluasi kegiatan pengabdian. Kegiatan pengabdian masyarakat dilakukan secara Virtual melalui Aplikasi Zoom Meeting. Kegiatan pengabdian ini dirangkaikan dengan Pertemuan Orang Tua Siswa dalam rangka memasuki awal semester tahun ajaran 2020-2021 di kedua mitra. Partisipan di SDIT Wihdatul Ummah adalah 493 orang dan di NICS sebanyak 35 orang yang merupakan siswa, guru, dan orang tua siswa. Sangat penting untuk menerapkan kebiasaan mencuci tangan dan peningkatan kemampuan/keterampilan membuat hand sanitizer bagi siswa, orang tua, dan guru dalam upaya mencegah  penyebaran penularan COVID-19
Co-Authors A. Rini Pratiwi Adinda S. Gaffar Amirullah Amirullah Andi Adelah Resmilasari Annisa Almagfirah Achmar As Adi Abdullah Audia Triani Olii Ayu Wulandari Ayyub Harly Nurung Bayu Putra Bayu Putra Dyah Nur Pratiwi Eka Nurshitya Fadelita Huath Fhahri Mubarak Harlyanti Muthma'innah Mashar Hendra Herman Herwin Herwin Herwin Herwin Ismail Ismail Magfirah Abdullah Maryana Maryana Mirawati Mirawati Nabila Adelina HM Naura Amalia Saliha Nur Sukma Dwi Priyanti Nurul Hasanah Nurul Ilmy Nurul Khatimah Naim Nurung, Ayyub Harly Putri Lestari Rachmat Kosman Rasma Maret Halina Restu Islamia Rasyak Reza Ariyadi Deponda Rizqi Nur Azizah Rusli Rusli Rusli Rusli Safriani Rahman Siska Nuryanti Sitti Amirah St. Maryam Tadjuddin Naid Tadjuddin Naid