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All Journal Jurnal Fitofarmaka Indonesia Journal of Pharmaceutical and Medicinal Sciences Jurnal Mandala Pharmacon Indonesia ad-Dawaa : Journal of Pharmaceutical Sciences Jurnal Pengabdian Kefarmasian Jurnal Abdi Masyarakat Kita
Sitti Rahimah
Sekolah Tinggi Ilmu Farmasi Makassar
Humanities Biochemistry, Genetics & Molecular Biology Chemistry Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Public Health

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Journal : ad-Dawaa : Journal of Pharmaceutical Sciences

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Analgesic and Antipyretic Effects of Jamblang (Syzygium cumini (l). Skeel) Leaves Ethanol Extract Suwahyuni Mus; Sitti Rahimah; Fadhilla Maryam
Ad-Dawaa: Journal of Pharmaceutical Sciences Vol 5 No 1 (2022)
Publisher : Universitas Islam Negeri Alauddin Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/djps.v5i1.31579

Abstract

Analgesic-antipyretic is a compound used to reduce pain and fever. This study aims to determine whether the ethanol extract of Syzygiumium cumini leaves has analgesic and antipyretic activity in mice (Mus musculus) induced by acetic acid and peptone. The method used was the Writhing method with acetic acid induction fanalgesiasic and the rectal temperature measurement method for antipyretic testing. This research was started by extracting Syzygium cumini (L.) Skeels leaves with 70% ethanol solvent by maceration. Syzygium cumini (L.) Skeels leaves extract was then tested in 5 groups the s, positive control growth as up given paracetamol for antipyretic testing and mefenamic acid for analgesic testing, negative control group ( Na.CMC suspension), a dose of 6 mg/Kg, 9 mg/Kg and 12 mg/Kg of body weight. The results indicate that the ethanol extract Syzygiumium cumini leaves has analgesic and antipyretic activity at all treatment doses and the most effectivect is at a dose of 6 kg BW KEYWORD : Syzygium cumini (L) Skeels, Mice, Analgesic, Antipyretic
Co-Authors Burhanuddin Taebe Dwi Anggara Putri Usman Fadhilla Maryam Fitriyanti Jumaetri Sami Gusri Nonde Harlyanti Muthma'innah Mashar Ismail Ismail Maria Ulfa Marwati Marwati Michrun Michrun Michrun Nisa Muh. Azwar Muhammad Azwar Musrifah Musrifah Nurfahmi Ruslan Radhia Riski Sukriani Kursia Suwahyuni Mus Tuti Handayani